Search clinical trials for: Immune Defects

Total 60451 results

Shenzhen Geno-Immune Medical Institute
The No.2 Clinical Hospital of the Ministry of Health

Recruiting

Frontline Combination CAR-T Cell Therapy for Multiple Myeloma or Plasmacytoma

Multiple Myeloma | Plasmacytoma

China, Russian Federation
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Characterization of Autoreactive Regulatory and Conventional CD4 T Cells in Recent Onset Type 1 Diabetes and Control Individuals (CARegT1D)

Type 1 Diabetes

France
University Hospital, Clermont-Ferrand

Not yet recruiting

The Role of Cytokines and Regulatory T Lymphocytes in Migraine Pathophysiology. (SIIM)

Pain | Multiple Sclerosis | Autoimmune Diseases | Rheumatoid Arthritis | Migraine Disorders | Endometriosis | Crohn Disease | Lupus Erythematosus

France
Xiao-Ming Mao
National Natural Science Foundation of China

Not yet recruiting

Graves' Disease Induced by Epstein-Barr Virus Lytic Reactivation

Graves Disease | Epstein-Barr Virus | Graves' Disease in Remission

China
Dr R Viswa Chandra

Recruiting

Efficacy of Insulin Like Growth Factor-1(IGF-1) on Bone Regeneration in Intrabony Defects : A Clinico-radiograph Study

Intrabony Periodontal Defect

India
Janssen Research & Development, LLC

Not yet recruiting

A Study Comparing Pre- and Post-Change Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma (MajesTEC-10)

Relapsed or Refractory Multiple Myeloma
Riphah International University

Recruiting

Effects of Liuzijue Exercise Versus Tai Chi Chuan Exercise in Asthma

Asthma

Pakistan
Tamar Nijsten

Recruiting

Effect of EMD Protocol for Urge on Dermatology-specific Quality of Life (EMD-U vs CAU)

Atopic Dermatitis | Prurigo Nodularis

Netherlands
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Phase II Study of Post-Transplant Low-Dose Inotuzumab Ozogamicin to Prevent Relapse of Acute Lymphoblastic Leukemia

Acute Lymphoid Leukemia

China
Henan Cancer Hospital

Not yet recruiting

This is a Phase II, Open-label, Multicentre Study of Zanubrutinib-containing Regimens in Patients With Newly Diagnosed Mantle Cell Lymphoma

Lymphoma, Non-Hodgkin | Lymphoma, Mantle-Cell
Lei-Miao Yin
Xiangya Hospital of Central South University; Shanghai 6th People's Hospital; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine and other collaborators

Not yet recruiting

Expressions of Ezrin and Pip5k1α Proteins in Airway Smooth Muscle of Asthmatic Patients

Asthma | Protein
Celgene

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma (GOLSEEK-2)

Lymphoma, Follicular

United States, Australia, Brazil, Canada, Chile, France, Germany, Italy, Korea, Republic of, Poland, Spain, Taiwan, United Kingdom
Colorado State University

Recruiting

Effects of a Microalgae Extract Dietary Supplement on Gut Health, Anxiety, and Immune Function (Tetrasol)

Stress | Anxiety | Gastrointestinal Symptoms | Gastrointestinal Problem

United States
Universitair Ziekenhuis Brussel
Vrije Universiteit Brussel

Not yet recruiting

The Potential Added Value of Impulse Oscillometry in Asthma Monitoring (AM-IOS)

Asthma
University Hospital, Ghent
University Ghent

Not yet recruiting

24-hour Movement Behaviors in Adults With Type 1 Diabetes (24h-MBs_T1D)

Diabetes Mellitus, Type 1

Belgium
Stanford University
American Heart Association

Not yet recruiting

Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries (MVP-ANOCA)

Angina Pectoris | Microvascular Angina | Vasospastic Angina | Myocardial Bridge of Coronary Artery

United States
Belgian Research on AIDS and HIV Consortium

Not yet recruiting

Use of Long-Acting Injectable Cabotegravir/Rilpivirine for the Treatment of HIV in Belgium

Human Immunodeficiency Virus
Sijia Gu

Not yet recruiting

Prospective Clinical Trial for Children With TCRαβ Depleted vs Traditional Haplo Identicle HSCT

Child, Only | Hematopoietic Stem Cell Transplantation | Graft-Versus-Host Disease | Haploidentical Hematopoietic Stem Cell Transplantation

China
National University Hospital, Singapore

Not yet recruiting

A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers (VALUE-CHECK)

Carcinoma, Hepatocellular | Gastric Adenocarcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Oesophageal Cancer | GastroEsophageal Cancer

Singapore
Fondazione Italiana Linfomi - ETS
Pierre Fabre Pharma AG

Not yet recruiting

PTLD: Multicentric Retrospective Study (FIL_PTLD)

PTLD

Italy
National Cancer Institute (NCI)

Not yet recruiting

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Undifferentiated Pleomorphic Sarcoma | Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
AstraZeneca

Recruiting

A Study To Evaluate The Treatment Pattern Of Moderate-to-Severe Asthma Patients In China (PRESENT)

Moderate-to-Severe Asthma

China
AstraZeneca
Premier HealthCare Solutions Inc.

Recruiting

Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on Health Outcomes in Routine Care (ANCHOR)

Asthma

United States
Radboud University Medical Center

Not yet recruiting

The Role of the Adrenergic System in Hypoglycaemia Induced Inflammatory Response in People With Type 1 Diabetes and People Without Type 1 Diabetes-RAID-II (RAID-II)

Inflammation | Diabetes Mellitus, Type 1
AbbVie

Not yet recruiting

An Observational Study to Assess Real-World Use of Upadacitinib Tablets in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis in China (REACH-AD)

Atopic Dermatitis
McGill University

Recruiting

Accuracy of a Continuous Ketone Monitoring (CKM) System in Individuals With Type 1 Diabetes on Insulin Pump Therapy. (CKM 1)

type1diabetes

Canada
Odense University Hospital

Recruiting

Long Term Effect of AIT in Children

Allergy in Children

Denmark
St. Jude Children's Research Hospital

Not yet recruiting

Cardiopulmonary Function and Cerebral Blood Flow in Hodgkin Lymphoma Survivors

Hodgkin Lymphoma, Adult

United States
Merck Sharp & Dohme LLC

Not yet recruiting

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

NSCLC | Non-small Cell Lung Cancer
Bristol-Myers Squibb

Not yet recruiting

Observational Study of Muscle Invasive Urothelial Carcinoma Participants Treated With Adjuvant Nivolumab in France (URADJ)

Urothelial Carcinoma

France
Oregon Health and Science University

Not yet recruiting

Two Way Crossover Closed Loop Study Insulin vs Insulin and Pramlintide

Type 1 Diabetes
Peking Union Medical College Hospital

Recruiting

Establishing Prospective Mediastinal Tumor Database of PUMCH (MTDPUMCH)

Lymphoma | Thymic Epithelial Tumor | Teratoma | Schwannoma | Germ Cell Tumor | Thymic Cyst | Retrosternal Goitre

China
National and Kapodistrian University of Athens
Recordati Rare Diseases

Recruiting

The Mechanism of Action of Chlormethine (CL) Gel in the Treatment of MF-CTCL Adult Patients (GR-CTCL_CL)

Mycosis Fungoides

Greece
Peking University Cancer Hospital & Institute

Recruiting

RC48 Treatment for Platinum Sensitive Recurrent Ovarian Cancer With HER2 Expression

Fallopian Tube Carcinoma | Ovarian Carcinoma | Primary Peritoneal Carcinoma

China
Ontario Clinical Oncology Group (OCOG)
Pfizer

Not yet recruiting

Outpatient and Intermittent Dosing of Elranatamab in Relapsed/Refractory Multiple Myeloma (EMBRACE)

Refractory Multiple Myeloma

Canada
Bristol-Myers Squibb

Recruiting

Observational Study in Japanese Patients With Peripheral T-Cell Lymphoma Who Received Second-Line Therapy

Peripheral T-cell Lymphoma

Japan
UGECAM Rhône-Alpes

Recruiting

Efficiency of Spatially Distributed Sequential Stimulation (Sdss) for Functional Electrical Stimulation (FES) of Upper Motor Neuron Syndrome (UMR) Patients (SDSS_UMS)

Upper Motor Neuron Disease

France
AstraZeneca

Not yet recruiting

A Non-interventional, Prospective Study With Benralizumab (AIR POWER)

Asthma, Bronchial
Aydin Adnan Menderes University

Recruiting

The Effect of Virtual Reality (VR) on Skin Prick Test Related Pain and Fear in Children

Pain | Allergy | Fear | Child, Only | Fear of Pain

Turkey
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Descriptive Analysis of Changes in Hepatitis B Markers in People Living With HIV on Injectable Therapy.

Hepatitis B | Hiv Infection

France
Case Comprehensive Cancer Center

Not yet recruiting

Brain MRF in Children, Adolescents and Young Adults With Acute Leukemia

Acute Leukemia | Acute Lymphoblastic Leukemia, Pediatric | Myeloproliferative Neoplasm | Acute Myeloid Leukemia in Children

United States
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Anti-CD19 CAR-NK Cells in Refractory/Relapsed Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

China
Yanyan Liu

Recruiting

Linperlisib Combined With Chidamide in Patients With PTCL

Peripheral T-cell Lymphoma

China
University of Pittsburgh
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

School Partnered Collaborative Care (SPACE) Intervention for Children With Type 1 Diabetes (SPACE)

Type 1 Diabetes

United States
Jinghui Wang

Recruiting

A Prospective, Single-arm, Phase II Clinical Trial to Evaluate the Efficacy and Safety of Tafolecimab and Sintilimab Combined With Chemotherapy in Patients With Advanced or Metastatic Driver Gene-negative Non-small Cell Lung Cancer After Failure of First-line Immunotherapy.

Lung Cancer

China
Istituto Clinico Humanitas
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Recruiting

Role of the Maternal Microbiota on the Immune Response and Metabolism During Hypertensive Disorders (MATER)

Preeclampsia

Italy
Essen Biotech

Not yet recruiting

Sequential CAR-T Cells Therapy for CD5/CD7 Positive T-cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma Using CD5/CD7-Specific CAR-T Cells (BAH246)

T Cell Lymphoma | T Cell Prolymphocytic Leukemia | T-cell Acute Lymphoblastic Leukemia | T Cell Leukemia | T-Cell Lymphoma of CNS | T Cell Childhood ALL

China
Istanbul University - Cerrahpasa (IUC)

Not yet recruiting

The Effect of Therapeutic Play on Anxiety and Fear Levels in Children With Diabetes

Type1diabetes | Anxiety State | Therapeutic Play | Fear State
Children's Hospital of Fudan University

Not yet recruiting

Development and Polit Study of Get Ready With my Heart Program

Congenital Heart Disease | Transition to Adult Care

China
Vittoria Biotherapeutics
University of Pennsylvania

Not yet recruiting

CD5-deleted Chimeric Antigen Receptor Cells (Senza5 CART5) for T Cell Non-Hodgkin Lymphoma (NHL) (VIPER101)

T Cell Non-Hodgkin Lymphoma

United States

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