Search clinical trials for: Immune cell metabolism

Total 111792 results

University of Chicago

Active, not recruiting

Allogenic Islet Cell Transplantation

Diabetes Mellitus, Type 1

United States
Medtronic Diabetes

Active, not recruiting

Evaluation of the MiniMed 780 System in Paediatric Subjects (LENNY)

Diabetes type1 | Children, Only

Italy, United Kingdom, Finland, Slovenia
Rodolfo Alejandro
University of Miami; National Institutes of Health (NIH); Health Resources and... and other collaborators

Active, not recruiting

Islet Cell Transplantation Alone in Patients With Type 1 Diabetes Mellitus: Steroid-Free Immunosuppression

Diabetes Mellitus, Type I

United States
Rodolfo Alejandro
Juvenile Diabetes Research Foundation; Diabetes Research Institute Foundation

Active, not recruiting

Allogeneic Islet Cells Transplanted Onto the Omentum

Hypoglycemia | Type 1 Diabetes Mellitus | Hypoglycemia Unawareness

United States
Duke University
National Institute of Nursing Research (NINR); National Institutes of Health...

Active, not recruiting

Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions (PiCASO)

Chronic Kidney Diseases | Diabetes Mellitus, Type 1 | Systemic Lupus Erythematosus | Inflammatory Bowel Diseases | Cystic Fibrosis | Sickle Cell Disease | Stem Cell Transplant | Childhood Cancer | Organ Transplant

United States
Prokidney

Active, not recruiting

Study of Renal Autologous Cell Therapy (REACT) in Subjects With Type 1 or 2 Diabetes and Chronic Kidney Disease (REGEN-007)

Chronic Kidney Diseases | Type 2 Diabetes Mellitus | Type 1 Diabetes Mellitus

United States
City of Hope Medical Center
National Institutes of Health (NIH)

Active, not recruiting

Islet Transplantation Alone (ITA) in Patients With Difficult to Control Type I Diabetes Mellitus Using a Glucocorticoid-free Immunosuppressive Regimen

Diabetes Mellitus

United States
Radboud University Medical Center

Active, not recruiting

Beta Cell Imaging During and Shortly After the Honeymoon Phase of T1D (Honeymoon)

Type 1 Diabetes Mellitus

Netherlands
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

Obesity | Psoriasis | Dyslipidemia | Atherosclerotic Cardiovascular Disease | Cardiometabolic Diseases

United States
Dompé Farmaceutici S.p.A

Terminated

A Study to Assess Efficacy/Safety of Ladarixin in Type 1 Diabetes Patients With Preserved ß-cell Function at Baseline.

New-onset Type 1 Diabetes

United States, Belgium, Georgia, Germany, Italy, Serbia
Dompé Farmaceutici S.p.A

Withdrawn

Ladarixin as Adjunctive Therapy to Improve Insulin Sensitivity and Glucometabolic Outcomes in Type 1 Diabetes

Type I Diabetes

United States
Jaeb Center for Health Research
Juvenile Diabetes Research Foundation; University of Minnesota

Active, not recruiting

Hybrid Closed Loop Therapy and Verapamil for Beta Cell Preservation in New Onset Type 1 Diabetes (CLVer): Extension Study (CLVerEx)

Type1 Diabetes

United States
University of Nebraska

Active, not recruiting

Healthy Bones, Healthy Life: Habitual Physical Activity on Bone & Metabolic Health in Pediatric Cancer Survivors (HBHL)

Lymphoma | Leukemia | Metabolic Syndrome | Osteoporosis | Bone Loss | Pediatric ALL | Acute Lymphoblastic Leukemia, Pediatric | Osteoporosis Risk | Pediatric | Lymphoid Leukemia | Pediatric Lymphoma | Habitual Physical Activity | Precursor Cell Lymphoblastic Leukemia

United States
Yang Tao

Completed

Immune Intervention With Rituximab to Preserve Beta Cell Function in Early Onset Type 1 Diabetes

Type 1 Diabetes

China
University of Colorado, Denver
National Center for Advancing Translational Sciences (NCATS)

Completed

Analysis of B Cells From Autoimmune Individuals

Rheumatoid Arthritis | Type 1 Diabetes | Lupus Erythematosus

United States
Provident Clinical Research
BioFortis; Dairy Research Institute

Completed

Clinical Trial to Assess the Effects of Dairy on Insulin Sensitivity and β-Cell Function

Diabetes

United States
LaTonya J. Hickson

Active, not recruiting

Stem Cell Therapy for Chronic Kidney Disease

Diabetes Mellitus, Type 2 | Diabetes Mellitus | Chronic Kidney Diseases | Diabetes Mellitus, Type 1 | Diabetic Nephropathies

United States
Centre Hospitalier Universitaire de Nīmes
Caisse Primaire d'Assurance Maladie du Gard

Completed

Link Between the Peripheral Mononuclear Cells' Capacity to Induce Insulin Resistance and Hyperinsulinemia (IRACTIV)

Insulin Resistance | Hyperinsulinism | Immune System

France
ViaCyte
California Institute for Regenerative Medicine (CIRM); Horizon 2020 - European...

Completed

A Safety, Tolerability, and Efficacy Study of VC-02™ Combination Product in Subjects With Type 1 Diabetes Mellitus and Hypoglycemia Unawareness

Type 1 Diabetes Mellitus With Hypoglycemia

United States, Canada, Belgium
medac GmbH
Syneos Health; Celerion; Venn Life Sciences

Completed

Treosulfan-based Versus Busulfan-based Conditioning in Paediatric Patients With Non-malignant Diseases

Bone Marrow Failure Syndromes | Inborn Errors of Metabolism | Primary Immunodeficiencies | Haemoglobinopathies

Poland, Czechia, Germany, Italy
University of Colorado, Denver
Children's Hospital Colorado; National Institutes of Health (NIH)

Completed

Microbiome Insulin Sensitivity Study (MISS)

Obesity | Insulin Resistance | Type2 Diabetes

United States
University of California, San Francisco

Completed

Study of Thiotepa and TEPA Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients

Sickle Cell Disease | Hemoglobinopathies | Fanconi Anemia | Thalassemia | Hematologic Malignancies | Immune Deficiency | Nonmalignant Diseases | Genetic Inborn Errors of Metabolism

United States
University of Florida
Live Like Bella Pediatric Cancer Research

Completed

Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation

Common Variable Immunodeficiency | Severe Combined Immunodeficiency | Sickle Cell Disease | Hurler Syndrome | Chronic Granulomatous Disease | Thalassemia | Wiskott-Aldrich Syndrome | Adrenoleukodystrophy | X-linked Lymphoproliferative Disease | Diamond Blackfan Anemia | Bone Marrow Failure Syndrome | Hemophagocytic... and other conditions

United States
University of Alberta
Juvenile Diabetes Research Foundation; Diabetes Research Institute Foundation; Alberta Diabetes Institute and other collaborators

Active, not recruiting

PolyTreg Immunotherapy in Islet Transplantation

Diabetes | Diabetes Mellitus, Type 1

Canada
CellTrans Inc.

Active, not recruiting

Islet Transplantation in Type 1 Diabetic Patients Using the University of Illinois at Chicago (UIC) Protocol

Type 1 Diabetes Mellitus

United States
University of Pennsylvania
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Active, not recruiting

Adrenergic System in Islet Transplantation

Hypoglycemia | Type1diabetes | Islet Cell Transplantation | Hypoglycemia Unawareness

United States
CellTrans Inc.

Approved for marketing

Islet Transplantation in Type I Diabetic Patients Using the University of Illinois at Chicago (UIC) Protocol

Type 1 Diabetes Mellitus

United States
Children's Hospital Los Angeles

Completed

Time Limited Eating in Type 1 Diabetes (TLET1D)

Type 1 Diabetes

United States
Andrew Posselt

Active, not recruiting

Treatment of Type I Diabetes by Islet Transplantation Into the Gastric Submucosa Study Protocol

Diabetes Mellitus, Type 1

United States
Assistance Publique - Hôpitaux de Paris
Iltoo Pharma

Completed

Low-dose rhIL-2 in Patients With Recently-diagnosed Type 1 Diabetes (DIABIL-2)

Type 1 Diabetes

Belgium, France, Germany, Netherlands, Sweden, Switzerland
MacroGenics
Eli Lilly and Company

Terminated

Protege Extension Trial - Long Term Follow Up Trial for Subjects Who Completed the Protege Study (CP-MGA031-01)

Type 1 Diabetes Mellitus

United States
Leiden University Medical Center

Completed

COVID-19 Glycemic Control Study

Type 1 Diabetes | Type 2 Diabetes

Netherlands
University of Alberta
Alberta Innovates Health Solutions

Active, not recruiting

Stem Cell Mobilization (Plerixafor) and Immunologic Reset in Type 1 Diabetes (T1DM)

Diabetes Mellitus, Type 1

Canada
The University of Texas Health Science Center at...
AstraZeneca

Completed

Effect of Chronic Exenatide Therapy on Beta Cell Function and Insulin Sensitivity in T2DM

Diabetes Mellitus, Type 2

United States
Indiana University
National Center for Advancing Translational Sciences (NCATS)

Completed

Effect of Prebiotics on the Gut Microbiome Profile and Beta Cell Function

Type 1 Diabetes

United States
Physicians Committee for Responsible Medicine
Yale University

Completed

Diet, Insulin Sensitivity, and Postprandial Metabolism (TEF)

Obesity | Overweight | Insulin Resistance

United States
Nemours Children's Clinic

Completed

Insulin Pump Therapy in Adolescents With Newly Diagnosed Type 1 Diabetes (T1D)

Diabetes Mellitus, Insulin-Dependent

United States
CRISPR Therapeutics AG
ViaCyte

Completed

An Open-Label, FIH Study Evaluating the Safety and Tolerability of VCTX210A Combination Product in Subjects With T1D

Glucose Metabolism Disorders | Immune System Diseases | Autoimmune Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Mellitus, Type 1 | Metabolic Disease

Canada
Brigham and Women's Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Active, not recruiting

Study of Vitamin D and Omega-3 Supplementation for Preventing Diabetes

Type 2 Diabetes

United States
Queen Mary University of London
AstraZeneca

Active, not recruiting

AZD1656 in Transplantation With Diabetes tO PromoTe Immune TOleraNce (ADOPTION)

Diabetes Mellitus, Type 2 | End Stage Renal Disease | Type 2 Diabetes | Renal Transplant | Kidney Transplant; Complications

United Kingdom
General and Teaching Hospital Celje

Completed

Novel Therapeutics and Endothelial Dysfunction in T1DM Patients (ENDIS)

Diabetes Mellitus, Type 1 | Biomarkers | Endothelial Dysfunction | Arterial Stiffness | FMD | Incretins | Endothelial Progenitor Cells | SGLT 2 Inhibitors | Glucose Excursions | FPF

Slovenia
Benaroya Research Institute

Completed

Targeting Beta Cell Dysfunction With Verapamil in Longstanding T1D

Type 1 Diabetes

United States
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

PET Imaging to Delineate Macrophage Activation in Diabetic Gastroparesis

Diabetes | Gastroparesis With Diabetes Mellitus

United States
University of British Columbia

Completed

Examining the Effect of Exogenous Ketone Supplementation on Glucose Control in Type 2 Diabetes

Diabetes Mellitus, Type 2

Canada
Mayo Clinic
Regenerative Medicine Minnesota

Terminated

Patient-Derived Stem Cell Therapy for Diabetic Kidney Disease

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Diabetic Kidney Disease | Diabetic Nephropathies | Chronic Kidney Disease | Kidney Failure | Diabetic Nephropathy Type 2 | Kidney Insufficiency

United States
NextCell Pharma Ab

Active, not recruiting

Wharton´s Jelly Derived Mesenchymal Stromal Cell Repeated Treatment of Adult Patients Diagnosed With Type I Diabetes

Type1diabetes

Sweden
NextCell Pharma Ab

Completed

Wharton´s Jelly Derived Mesenchymal Stromal Cell Treatment of Adult Patients Diagnosed With Type I Diabetes

Type1 Diabetes Mellitus

Sweden
New York Stem Cell Foundation Research Institute
Laser and Skin Surgery Center of New York

Active, not recruiting

Biological Sample Collection for Research and Biobanking

Macular Degeneration | Cancer | Diabetes Mellitus, Type 1 | Parkinson Disease | Alzheimer Disease | ALS | Huntington Disease

United States
Calithera Biosciences, Inc

Terminated

Study CB-839 in Combination With Nivolumab in Patients With Melanoma, Clear Cell Renal Cell Carcinoma (ccRCC) and Non-Small Cell Lung Cancer (NSCLC)

Melanoma | Non-small Cell Lung Cancer (NSCLC) | Clear Cell Renal Cell Carcinoma (ccRCC)

United States
Indiana University
Juvenile Diabetes Research Foundation

Completed

Identification of β Cell Dysfunction in Relatives of Individuals With Type 1 Diabetes Mellitus

Type 1 Diabetes

United States

Search clinical trials for: Immune cell metabolism

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