Search clinical trials for: Latent reservoir

Total 719 results

University of Miami

Recruiting

Two Biologically and Clinically Distinct Entities: Progressive Versus Stable Multiple Myeloma (MM) Precursor Conditions (TRANSFORMM)

Multiple Myeloma | Monoclonal Gammopathy of Undetermined Significance | Smoldering Multiple Myeloma

United States
Baylor College of Medicine
London School of Hygiene and Tropical Medicine; Centers for Disease Control... and other collaborators

Recruiting

Closing -TB GAPs - for People Living With HIV: TB Guidance for Adaptable Patient-Centered Service (TB_GAPS)

Tuberculosis | HIV Coinfection | Tuberculosis Infection

Swaziland
Roswell Park Cancer Institute

Recruiting

Non-chemotherapeutic Interventions for the Improvement of Quality of Life and Immune Function in Patients With Multiple Myeloma

Plasma Cell Myeloma | Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma | Smoldering Plasma Cell Myeloma

United States
Hôpital Européen Marseille

Recruiting

Evolution of HIV Reservoir, Inflammation and Microbiota Footprint of PLWH Switching to Long-acting Injectable Treatment Compared to Patients on Oral Dual or Triple Anti-integrase-based Therapy (LAMIVIH)

HIV Infections

France
Peking University First Hospital

Recruiting

A Cohort Study of Plasma Cell Disorders (PCDs) in PKUFH

Multiple Myeloma | Amyloidosis | Smoldering Multiple Myeloma | Plasma Cell Leukemia | Cryoglobulinemia | Light Chain Deposition Disease | Castleman's Disease | Heavy Chain Deposition Disease | Polyneuropathy Organomegaly Endocrinopathy Monoclonal Gammopathy and Skin Changes | Monoclonal Gammopathy of Undetermined... and other conditions

China
Johns Hopkins University
National Heart, Lung, and Blood Institute (NHLBI); Walimu

Recruiting

Clinic-based Versus Hotspot-focused Active TB Case Finding (CHASE-TB)

Tuberculosis, Pulmonary | Mycobacterium Tuberculosis Infection

Uganda
Inje University
Ministry of Science and ICT

Recruiting

Multi-site Cohort Study for the Development of Personalized Pharmacotherapy in Patients With Tuberculosis (TB)

Latent Tuberculosis | Tuberculosis | Nontuberculous Mycobacterium Infection

Korea, Republic of, Indonesia
University of Namibia
European and Developing Countries Clinical Trials Partnership (EDCTP); Research... and other collaborators

Recruiting

Collision of Three Global Pandemics: the Effect of Tuberculosis and HIV on the Epidemiological, Clinical, Virological and Immunological Trajectory of COVID-19 in Botswana and Namibia (Core-NB)

COVID-19 | HIV Seropositivity | Tuberculosis, Pulmonary | Tuberculosis Infection

Namibia
Bahir Dar University

Recruiting

Effect of Integrating Traditional Tuberculosis Care With Modern Health Care on Case Detection

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis Infection

Ethiopia
ANRS, Emerging Infectious Diseases
Gilead Sciences

Not yet recruiting

A Study to Determine the Cartography of Virologic Reservoir Related to Antiretroviral Concentrations in HIV-1 Chronic Patients Treated by a First Line Treatment Containing bictégravir, Emtricitabine and ténofovir alafénamide

HIV-1-infection

France
Pomeranian Medical University Szczecin

Not yet recruiting

Early-initiated High Flow Oxygen Therapy vs Conventional Oxygen Therapy Among Patients With ARDS in the Course of SARS-CoV2 Pneumonia.

Oxygen Deficiency | Corona Virus Infection | ARDS Due to Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2

Poland
Cogent Biosciences, Inc.

Recruiting

(Summit) A Study to Evaluate the Efficacy and Safety of CGT9486 Versus Placebo in Patients With Indolent or Smoldering Systemic Mastocytosis

Mastocytosis | Mastocytosis, Systemic | SSM | Mastocytosis, Indolent

United States, Italy, Canada, Australia, Spain, Switzerland, Norway, United Kingdom, Belgium, Poland, Netherlands, Germany, France, Czechia, Greece, Ireland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Quality of Life in Patients With Asymptomatic Monoclonal Gammopathies

Monoclonal Gammopathy of Undetermined Significance | Smoldering Plasma Cell Myeloma

United States
The Aurum Institute NPC
Johns Hopkins University; Weill Medical College of Cornell University; University...

Recruiting

Safety and Tolerability of 1 Month Daily (1HP) and 3 Months Weekly (3HP) Isoniazid and Rifapentine With Pharmacokinetics of Dolutegravir (DTG) in Pregnant People With HIV (DOLPHIN Moms)

Pregnancy | HIV Seropositivity | Tuberculosis Infection

South Africa
Region Skane

Recruiting

Rifampicin Resistance in S. Aureus During and After Treatment for Latent Tuberculosis

Staphylococcus Aureus | Latent Tuberculosis

Sweden
Fundación FLS de Lucha Contra el Sida, las Enfermedades...

Recruiting

Alternative Antibiotics for Syphilis

Primary Syphilis | Secondary Syphilis | Early Latent Syphilis

Spain, United Kingdom
Brigham and Women's Hospital
University of Cape Town; APIN Public Health Initiatives

Recruiting

Dolutegravir Pharmacokinetics Among HIV/TB Coinfected Children Receiving Standard and High-dose Rifampicin

Tuberculosis Infection | Pediatric HIV Infection

Nigeria
University of Castilla-La Mancha

Not yet recruiting

Influence of Latent Miofascial Trigger Points in the Vertical Jump in Female Voleyball Players (LMTP_Volley)

Sports Physical Therapy

Spain
M.D. Anderson Cancer Center

Recruiting

A Phase 1 With Extension Cohort, Single Arm, Single Center, Open Label Trial of Belantamab Mafodotin for the Treatment of High-Risk Smoldering Multiple Myeloma

Myeloma

United States
University College, London
Cancer Research UK

Recruiting

Biology and Genetics of Smouldering Myeloma (COSMOS)

Multiple Myeloma | MGUS | Smouldering Myeloma

United Kingdom
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens Into the Human Lung

Healthy | Latent Tuberculosis Infection (LTBI)

United States
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Economic Incentives and vDOT for Latent Tuberculosis Infection

Latent Tuberculosis

United States
Novo Nordisk A/S

Recruiting

ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation (ZEUS)

Inflammation | Chronic Kidney Disease | Cardiovascular Risk

Korea, Republic of, Spain, China, Taiwan, Mexico, Netherlands, Latvia, Malaysia, United States, Thailand, Hungary, Australia, Poland, South Africa, India, Portugal, Romania, United Kingdom, Brazil, Sweden, Italy, Lithuania, Japan, Serbia and more
Miguel Santín
Institut d'Investigació Biomèdica de Bellvitge; Instituto de Salud Carlos III

Not yet recruiting

Short-course Rifamycin-based Regimens for Latent Tuberculosis in Patients With End-stage Kidney Disease

Latent Tuberculosis | Kidney Failure
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Leflunomide for the Treatment of High-Risk Smoldering Multiple Myeloma in African-American and European-American Patients

Smoldering Plasma Cell Myeloma

United States
National Taiwan University Hospital

Recruiting

Latent TGF-β-binding Proteins Affect the Fibrotic Process in Renal Impairment and Cardiac Dysfunction

Acute Coronary Syndrome | Acute Coronary Syndrome With Renal Dysfunction

Taiwan
UBP Greater China (Shanghai) Co., Ltd

Not yet recruiting

A Proof of Concept Study to Evaluate the Effect of UB-421 in Combination With Chidamide on HIV Viral Reservoir

HIV-1-infection
Kenya Medical Research Institute
European and Developing Countries Clinical Trials Partnership (EDCTP)

Recruiting

Latent HIV-1, Viral Suppress and Hope for HIV Cure

HIV-1-infection

Kenya
Zeynep Kamil Maternity and Pediatric Research and...

Recruiting

Isthmocele Development Due to Primary Cesarean Section at The Latent or Active Phase (Isthmocele)

Uterus; Scar

Turkey
University of Sao Paulo General Hospital
InCor Heart Institute

Recruiting

Angiotensin Receptor-Neprilysin Inhibition in Chagas Cardiomyopathy With Reduced Ejection Fraction: ANSWER-HF. (ANSWER-HF)

Chagas Cardiomyopathy

Brazil
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Recruiting

Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma

Monoclonal Gammopathy of Undetermined Significance | Smoldering Multiple Myeloma

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Surgical Resection of Latent Brain Tumors Prior to Recurrence

Brain Neoplasm

United States
Emory University
Bristol-Myers Squibb; National Cancer Institute (NCI)

Recruiting

Iberdomide Alone or in Combination With Dexamethasone for the Treatment of Intermediate- or High-Risk Smoldering Multiple Myeloma

Smoldering Plasma Cell Myeloma

United States
Omar Nadeem, MD
Janssen, LP

Recruiting

DARA RVD For High Risk SMM (PRISM)

Multiple Myeloma | High-risk Smoldering Multiple Myeloma

United States
University of Rochester

Recruiting

Curcumin and Piperine in Patients on Surveillance for Monoclonal Gammopathy, Smoldering Myeloma or Prostate Cancer

Multiple Myeloma | Prostate Cancer | Monoclonal Gammopathy of Undetermined Significance | Smoldering Multiple Myeloma (SMM)

United States
HealthTree Foundation
GlaxoSmithKline

Recruiting

MGUS, SMM, and MM Patient Experience With Coronavirus 19 (COVID-19) Survey

Multiple Myeloma | Monoclonal Gammopathy of Undetermined Significance | Smoldering Multiple Myeloma | Coronavirus

United States
ANRS, Emerging Infectious Diseases
University Hospital, Caen; Institut de Recherche pour le Developpement; Centre... and other collaborators

Not yet recruiting

Epidemiological Investigation of COVID-19 in Laos Using a One-Health Approach in Human and Animals (LACOVISS)

Covid19 | Influenza -Like Illness
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Ommaya Reservoir Placement for Brain Tumor Biomarker Access

Brain Tumor

United States
Thomayer University Hospital
Charles University, Czech Republic

Recruiting

Cytometric Immunodiagnostics of Latent Tuberculosis Infection (LTBI)

BCG Vaccination Reaction | LTBI | TB

Czechia
Steven Deeks
Caring Cross

Recruiting

CAR-T Cells for HIV Infection

HIV Infections

United States
Tuberculosis Research Centre, India
National Institutes of Health (NIH)

Recruiting

Comorbidities and Coinfections in Latent TB (COMBINE-TB)

Malnutrition | Latent Tuberculosis | Diabete Mellitus | Helminth Infection

India
Dr. Nyanda Elias Ntinginya
King's College London; Makerere University; Stichting Katholieke Universiteit-... and other collaborators

Recruiting

Preventive Treatment Of Latent Tuberculosis Infection In People With Diabetes Mellitus (PROTID)

Diabetes Mellitus | Tuberculosis

Uganda, Tanzania
Fundació Institut Germans Trias i Pujol
National Center for Tuberculosis and Lung Disease, Tbilisi, Georgia; Perinatal...

Recruiting

Adjunctive Acetylsalicylic Acid and Ibuprofen for Tuberculosis (SMA-TB)

Tuberculosis, Pulmonary | Tuberculosis Infection | Tuberculosis, MDR

South Africa, Georgia
Zhejiang University

Recruiting

A Study of CAR-T Cells Therapy for Patients With Relapsed and/or Refractory Central Nervous System Hematological Malignancies

Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia

China
Huashan Hospital

Not yet recruiting

MDR-TB Close Contacts Tracing in China (TCCT Study)

Multidrug Resistant Tuberculosis

China
National Cancer Center Hospital East
Alpha-A, Inc.

Recruiting

Initial Attack on Latent Metastasis Using TAS-102 for ct DNA Identified Colorectal Cancer Patients After Curative Resection (ALTAIR)

Colorectal Neoplasms | Circulating Tumor DNA | Trifluridine and Tipiracil

Japan, Taiwan
Henry M. Jackson Foundation for the Advancement...
United States Department of Defense; Uniformed Services University of the Health...

Recruiting

Immunization With BCG Vaccine to Prevent Tuberculosis Infection (TIPI)

Tuberculosis Infection

United States
University of California, San Francisco
Chan Zuckerberg Biohub

Recruiting

SCOPE Analytic Treatment Interruption Protocol (SCOPE-ATI)

HIV/AIDS

United States
AB Science

Recruiting

Masitinib in Severe Indolent or Smoldering Systemic Mastocytosis Unresponsive to Optimal Symptomatic Treatment

Indolent Systemic Mastocytosis

France, Netherlands, Germany, United Kingdom, Russian Federation, Poland, Romania, Ukraine
Hospices Civils de Lyon

Recruiting

Immunological Biomarkers in Tuberculosis Management (OPTI-4TB)

Tuberculosis | Tuberculosis Infection

France

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