Search clinical trials for: Moderate to severe sensorimotor diabetic polyneuropathy

Total 477690 results

Sanofi Pasteur, a Sanofi Company

Recruiting

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

Acne

United States
Aqpha Medical B.V.

Not yet recruiting

Safety and Performance of PTMC Dermal Filler

Moderate to Severe Nasolabial Fold
Societa Italiana di Dermatologia Medica, Chirurgica...

Recruiting

National Register of Moderate and Severe Adult Atopic Dermatitis (ATOPYREG)

Atopic Dermatitis

Italy
Xiyuan Hospital of China Academy of Chinese Medical...

Recruiting

Study to Evaluate the Efficacy, Safety and Tolerability of Photodynamic Therapy(PDT) With Chlorin-e6 in Treating Moderate to Severe Acne

Acne | Photodynamic Therapy

China
LEO Pharma

Recruiting

A Trial to Evaluate the Efficacy and Safety of Tralokinumab in Combination With Topical Corticosteroids in Children and Infants With Moderate-to-severe Atopic Dermatitis (TRAPEDS 2)

Atopic Dermatitis

United States
Wuhan Union Hospital, China

Recruiting

Anti-CD19 CAR-T Cell Therapy in Participants With Moderate to Severe Active Systemic Lupus Erythematosus

Safety | Effective

China
Fate Therapeutics

Recruiting

FT819 in Moderate to Severe Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States
ImmuneMed, Inc.

Not yet recruiting

A Study to Assess the Efficacy and Safety of Burfiralimab (hzVSF-v13) and DMRD (Disease-modifying Antirheumatic Drug)

Moderate to Severe Rheumatoid Arthritis

Netherlands
Shanghai Eye Disease Prevention and Treatment Center
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Recruiting

Efficacy and Safety of Conbercept for Diabetic Macular Edema Combined With Severe Non-proliferative Diabetic Retinopathy

Diabetic Macular Edema

China
Florida Academic Centers Research and Education...

Not yet recruiting

Evaluate the Efficacy of TIRZEPATIDE for the Treatment of Moderate to Severe HS Hidradenitis Suppurativa

Hidradenitis Suppurativa
Eli Lilly and Company

Recruiting

Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)

Type 2 Diabetes

United States, Argentina, United Kingdom, Puerto Rico
Shanghai Ming Ju Biotechnology Co., Ltd.

Not yet recruiting

Relma-cel for Moderate to Severe Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Merck Sharp & Dohme LLC

Not yet recruiting

A Study of MK-8527 in Participants With Moderate and Severe Renal Impairment (MK-8527-008)

Renal Impairment
Gilead Sciences

Recruiting

Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis (SWIFT)

Ulcerative Colitis

United States
Jiani Wu

Not yet recruiting

TaVNS Improves the Symptoms of Patients With Moderate to Severe CP/CPPS

Chronic Prostatitis

China
UNICEF - Venezuela

Recruiting

Treatment of Acute Malnutrition in Outpatient Care Services in Venezuela: a Prospective Cohort Research

Wasting | Acute Malnutrition in Childhood | Child Malnutrition

Venezuela
University of Arizona
United States Department of Defense

Not yet recruiting

Safety and Efficacy of Angiotensin (1-7) in Persons With Moderate to Severe Traumatic Brain Injury (ANGel T)

Traumatic Brain Injury
Innovaderm Research Inc.

Not yet recruiting

Efficacy, Safety, and Tolerability of Abrocitinib in Subjects With Moderate to Severe Chronic Hand Eczema Refractory to Corticosteroid Therapy

Chronic Hand Eczema

Canada
Eli Lilly and Company

Recruiting

A Study of Lebrikizumab (LY3650150) With/Without Topical Corticosteroid Treatment in Participants With Moderate-to-Severe Atopic Dermatitis

Atopic Dermatitis

China, Korea, Republic of
InventisBio Co., Ltd

Recruiting

Evaluate the Efficacy and Safety of D-2570 in Participants With Moderate-to-Severe Plaque Psoriasis

Plaque Psoriasis

China
Lynk Pharmaceuticals Co., Ltd

Recruiting

A Phase 3 Study of LNK01001 Capsule in Subjects With Moderate to Severe Atopic Dermatitis.

Atopic Dermatitis

China
Baylor College of Medicine
University of Texas

Recruiting

Telehealth Behavioral Activation for Teens

Depression | Depression Moderate | Depression Severe | Suicide and Self-harm | Depression in Adolescence | Depression Mild

United States
EMS

Not yet recruiting

Efficacy and Safety of DEP114 in the Treatment of Moderate to Severe Persistent Allergic Rhinitis in Children. (SIERRA)

Allergic Rhinitis
Janssen Research & Development, LLC

Recruiting

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis (QUASAR Jr)

Colitis, Ulcerative

Belgium, United States, China, Denmark, Spain, Japan, Italy, Turkey, France, Australia, Poland, Portugal
Tasly Pharmaceutical Group Co., Ltd

Recruiting

A Study of the Effectiveness and Safety of JS1-1-01 in Patients With Moderate to Severe Depression

Depression

China
Bristol-Myers Squibb

Not yet recruiting

Real-World Safety and Effectiveness of Sotyktu (Deucravacitinib) in Patients With Moderate-to-Severe Plaque Psoriasis in Korea

Moderate-to-severe Plaque Psoriasis

Korea, Republic of
Alimentiv Inc.
Takeda

Not yet recruiting

VECTORS - A Study to Evaluate Transmural Healing as a Treatment Target in Crohn's Disease (VECTORS)

Crohn Disease | Moderately to Severely Active Crohn's Disease | Disease Crohn
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Trial of HHPG-19K Injection and Auto-HHPG-19K Injection in Prevention of Chemotherapy-related Moderate to Severe Neutropenia of Patients With Nonmyeloid Malignancies

Patients With Nonmyeloid Malignancies Receiving Antineoplastic Therapy Based on Chemotherapy Regimens at Moderate to High Febrile Neutropenia (FN) Risk

China
Century Therapeutics, Inc.

Not yet recruiting

A Study of CNTY-101 in Participants With Moderate to Severe Systemic Lupus Erythematosus (SLE) (CALiPSO-1)

Systemic Lupus Erythematosus
Takeda

Recruiting

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis

United States, France, Hungary, Korea, Republic of, Belgium, Japan, Germany, Canada, Italy, Poland, Czechia, Denmark, Greece, Norway, Romania, Slovakia, United Kingdom
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Recruiting

Comparative Study of Metformin Versus Doxycycline in Moderate to Severe Adult Acne Vulgaris Patients.

Acne Vulgaris

Bangladesh
Ascletis Pharmaceuticals Co., Ltd.

Not yet recruiting

A Study to Evaluate Safety of ASC40 Tablets in Patients With Moderate to Severe Acne Vulgaris

Acne
Amgen

Recruiting

A Trial to Investigate Teprotumumab Subcutaneous Administration Compared With Placebo in Male and Female Adult Participants With Moderate-to-severe Active Thyroid Eye Disease

Thyroid Eye Disease

United States
Jetema USA Inc.

Not yet recruiting

Clinical Trial to Evaluate the Safety and Efficacy of JTM201 to Treat Moderate or Severe Glabellar Lines

Glabellar Lines
Amgen

Recruiting

A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State

Sjögren's Syndrome (SS)

United States, Japan
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor (AQUA)

Dermatitis Atopic

Argentina, Chile, Germany, Japan, Spain, United Kingdom, Canada, United States, Brazil, France, Turkey, Israel, Korea, Republic of, China
Shanghai 6th People's Hospital

Not yet recruiting

Safety and Efficacy of Enhanced Recovery After Surgery in Neurocritical Care

Traumatic Brain Injury | Cerebrovascular Disease | Neurocritical Care | Moderate or Severe Coma

China
medac GmbH

Recruiting

Efficacy and Safety of Methotrexate Versus Placebo in Adults With Atopic Dermatitis.

Moderate to Severe Atopic Dermatitis

France, Poland, Italy, Czechia
EMS

Not yet recruiting

Efficacy and Safety of DIT112 in the Treatment of Moderate to Severe Pain After Dental Surgery for the Extraction of Impacted Third Molars (ALIV)

Moderate Pain | Severe Pain
Takeda

Recruiting

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease

United States, Australia, France, Taiwan, Hungary, Korea, Republic of, Spain, Switzerland, China, Japan, Belgium, Canada, Germany, Italy, Poland, Romania, United Kingdom, Czechia, Denmark, Greece, Norway, Slovakia, Netherlands
Morphic Therapeutic, Inc

Recruiting

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease (GARNET)

Inflammatory Bowel Diseases | Crohn's Disease

United States, Georgia
McMaster University
Center for Medicinal Cannabis Research

Not yet recruiting

Psilocybin in the Treatment of Cannabis Use Disorder: A-Proof-of-Concept Study (PSI_CUD)

Cannabis Use Disorder, Moderate | Cannabis Use Disorder, Severe
Amgen

Recruiting

A Study With Self-administered Rocatinlimab in Adolescent and Adult Participants With Moderate-to-severe AD (ROCKET-Outpost)

Atopic Dermatitis

United States, Canada
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis on Background Topical Corticosteroids (SHORE)

Dermatitis Atopic

Japan, Chile, Canada, Argentina, Brazil, France, United States, Turkey, China
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis (ICONIC-ADVANCE 2)

Plaque Psoriasis

United States, Korea, Republic of, Taiwan, Germany, Poland, Brazil, Spain, Hungary, Australia, Canada, Romania
Incyte Corporation

Recruiting

A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa (STOP-HS LTE)

Hidradenitis Suppurativa (HS)

United States, Austria, Belgium, Canada, Germany, Poland, Spain, Australia, Denmark, France, United Kingdom, Japan, Bulgaria, Netherlands, Czechia, Greece, Italy
Assistance Publique Hopitaux De Marseille

Not yet recruiting

Effects on Biotrauma of NMBAs and PP Association During ARDS (CURA-PRONE)

Moderate to Severe Acute Respiratory Distress Syndrome

France
Fidia Farmaceutici s.p.a.

Recruiting

Assessment of Efficacy and Safety of the Use of Two Eye Gel Products Containing 5% Dexpanthenol in Patients With Moderate to Severe Dry Eye Syndrome

Dry Eye Disease

Italy
JHM BioPharma (Tonghua) Co. , Ltd.

Recruiting

A Phase I/II, Randomized, Double-blind, Placebo, and Active Controlled Clinical Study to Evaluate the Safety, Tolerability, Immunogenicity, and Preliminary Efficacy of JHM03 in Subjects With Moderate to Severe Glabellar Lines

Moderate to Severe Glabellar Lines

China
Ascletis Pharmaceuticals Co., Ltd.

Recruiting

A Study to Evaluate the Safety and Efficacy of ASC40 (Denifanstat) Tablets in the Treatment of Patients With Moderate to Severe Acne Vulgaris

Acne

China

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