Search clinical trials for: brimonidine

Total 179 results

Biogen

Withdrawn

Brimonidine Tartrate for the Treatment of Injection Related Erythema (BRITE)

Relapsing-Remitting Multiple Sclerosis (RRMS)
DSM Nutritional Products, Inc.
Abbott Nutrition

Completed

Effects of Lutein on Learning and Memory in Chronically Stressed Subjects and in an Acute Stressful Situation (TSST - Trier Social Stress Test): A Randomized, Double-blind, Placebo-controlled Trial) (MemLearn)

Healthy But Chronically Stressed

Germany
BCN Peptides

Completed

Trial to Assess the Efficacy of Neuroprotective Drugs Administered Topically to Prevent or Arrest Diabetic Retinopathy (EUROCONDOR)

Diabetic Retinopathy

Denmark, France, Germany, Italy, Portugal, Spain, United Kingdom
University of California, Los Angeles

Completed

Earlier Intraocular Pressure Control After Ahmed Glaucoma Valve Implantation for Glaucoma

Glaucoma

United States
Bayer

Completed

PK in Pts With HRPC & Skeletal Metastes

Prostatic Neoplasms

United Kingdom
Carmel Medical Center

Unknown

The Effect of Topical Treatment With Combigan Compared to Timolol and Brimonidine on Pupil Diameter

Healthy

Israel
Derm Research, PLLC
Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma

Completed

Finacea 15% and Brimonidine 0.33% Gel in the Treatment of Rosacea - A Pilot Study

Acne Rosacea

United States
Alcon Research

Completed

Assessing the Efficacy and Tolerability of AZARGA® (Brinzolamide 1%/Timolol 0.5% Fixed Combination) as Replacement Therapy in Patients on Brimonidine 0.2%/Timolol 0.5% Fixed Combination Therapy (COMBIGAN®) in Latin America

Glaucoma
Alcon Research

Completed

Effect of SIMBRINZA® Suspension as an Added Therapy to a Prostaglandin Analogue

Ocular Hypertension | Open Angle Glaucoma
Alcon Research

Completed

Effect of SIMBRINZA® Suspension as an Added Therapy to TRAVATAN Z®

Ocular Hypertension | Open Angle Glaucoma
Alcon Research

Completed

Evaluation of Intraocular Pressure Using Simbrinza™ in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma
Allergan

Completed

Safety Extension Study to Evaluate the Biodegradation of the Brimonidine Tartrate Posterior Segment Drug Delivery System

Patients Who Participated in an Intravitreal Brimo PS DDS® Study

France, United Kingdom, Korea, Republic of, Czech Republic, Australia, Israel, India, Portugal, Germany, United States, Italy, Philippines
Allergan

Completed

A Safety and Efficacy Study of Fixed-Combination Bimatoprost and Brimonidine in Chronic Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma

United States
Medical University of Vienna

Withdrawn

Relation Between Intraocular Pressure Lowering Effects of Topical Brimonidine and Alpha 2 Receptor Polymorphism

Intraocular Pressure | Ocular Physiology

Austria
Medical University of Vienna

Withdrawn

Effects of Common Topical Glaucoma Therapy on Optic Nerve Head Blood Flow Autoregulation During Increased Arterial Blood Pressure and Artificially Elevated Intraocular Pressure in Healthy Humans

Glaucoma

Austria
Medical University of Vienna

Completed

Effect of Xalacom® (Latanoprost/Timolol) and Combigan® (Brimonidine/Timolol) Fixed Combination on Intraocular Pressure and Ocular Blood Flow in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Ocular Physiology | Retina

Austria
Allergan

Completed

Safety and Efficacy of Triple Combination Therapy in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma, Open-Angle

Mexico, Colombia
Eye Therapies, LLC

Completed

Study Evaluating the Safety and Efficacy of Brimonidine Tartrate Ophthalmic Solution in Adult and Geriatric Subjects

Ocular Redness

United States
Allergan

Completed

A Study of 0.15% Brimonidine Tartrate in Patients With Primary Open Angle Glaucoma and Ocular Hypertension (APOTUS)

Ocular Hypertension | Glaucoma, Open-Angle

China
Mashhad University of Medical Sciences

Completed

Effect of Antiglaucoma Agents on Short Term Intraocular Pressure Fluctuations After Intravitreal Bevacizumab Injection

Intraocular Pressure Change in Intravitreal Injection

Iran, Islamic Republic of
Aristotle University Of Thessaloniki

Completed

24-hr Intraocular Pressure Control With Dorzolamide/Timolol vs the Brimonidine/Timolol Fixed Combination

Glaucoma

Greece
Alcon Research

Completed

Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID Plus Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma
Allergan

Completed

Safety and Efficacy of Combigan® Ophthalmic Solution in Korea

Ocular Hypertension | Glaucoma, Open-Angle

Korea, Republic of
Alcon Research

Completed

Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID and Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma
University Hospital, Basel, Switzerland

Completed

Effect of Alphagan and Xalatan Eye Drops on Corneal Temperature

Primary Vascular Dysregulation

Switzerland
Allergan

Completed

A Safety and Efficacy Study of ALPHAGAN® P and LUMIGAN® in Subjects Previously Treated With Latanoprost for Glaucoma and Ocular Hypertension

Ocular Hypertension | Glaucoma

United States
Alcon Research

Terminated

Assessing the Efficacy and Tolerability of AZARGA® (Brinzolamide 1%/Timolol 0.5% Fixed Combination) as Replacement Therapy in Patients on COMBIGAN® (Brimonidine 0.2%/Timolol 0.5% Fixed Combination) Therapy in Brazil

Glaucoma

Brazil
Allergan

Completed

Safety and Efficacy of Triple Combination Therapy in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma

India
Allergan

Completed

Pharmacokinetics of the Brimonidine Tartrate Posterior Segment Delivery System in Patients Undergoing Pars Plana Vitrectomy

Vitrectomy

United States, Czech Republic
Allergan

Withdrawn

Safety and Efficacy of Triple Combination Therapy With Dorzolamide Hydrochloride / Brimonidine Tartrate / Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma
Alcon Research

Completed

A Comfort Study of Brinzolamide 1% / Brimonidine 0.2% Fixed Combination, Brinzolamide 1% and Brimonidine 0.2%

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Terminated

Safety and Efficacy of Brinzolamide/Brimonidine Fixed Combination

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Completed

Three Month Efficacy/Safety Study With a 3-Month Safety Extension of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% or Brimonidine 0.2%

Ocular Hypertension | Open-Angle Glaucoma
University of Sao Paulo General Hospital

Completed

Transconjunctival Needling Revision Versus Medical Treatment

Primary Open Angle Glaucoma

Brazil
Alcon Research

Completed

Efficacy and Safety Study of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% and Brimonidine 0.2%

Ocular Hypertension | Open-Angle Glaucoma
National Cancer Institute (NCI)

Completed

Hormone Therapy in Preventing Endometrial Cancer in Patients With a Genetic Risk For Hereditary Nonpolyposis Colon Cancer

Endometrial Cancer

United States
Allergan

Completed

Safety and Effects of Brimonidine Intravitreal Implant in Patients With Glaucomatous Optic Neuropathy

Glaucoma, Open-Angle

Israel, United States
Allergan

Completed

Safety and Efficacy of Brimonidine Tartrate Posterior Segment Drug Delivery System in Improving Visual Function

Rhegmatogenous Macula-off Retinal Detachment

United Kingdom, Korea, Republic of, Israel, India, United States, Philippines
Allergan

Completed

An Exploratory Study to Evaluate the Safety of Brimonidine Intravitreal Implant in Patients With Retinitis Pigmentosa

Retinitis Pigmentosa

France, United States, Germany, Portugal
Alcon Research

Completed

Circadian Ocular Perfusion Pressure and Ocular Blood Flow

Glaucoma

United States
Allergan

Terminated

Study of Brimonidine and Timolol Ophthalmic Solution With Latanoprost Compared With Latanoprost in Glaucoma Patients

Glaucoma, Angle-Closure

Thailand
Eye Therapies, LLC

Completed

Study Evaluating the Safety and Intraocular Pressure (IOP) Lowering Response of Brimonidine Tartrate Ophthalmic Solution in Subjects With Open Angle Glaucoma or Ocular Hypertension

Glaucoma and Ocular Hypertension

United States
Allergan

Completed

Safety and Efficacy of Brimonidine Tartrate/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma

China
University Hospital "Sestre Milosrdnice"

Completed

The Influence of Silicone Oil on Nerve Fiber Layer Thickness After Pars Plana Vitrectomy

Rhegmatogenous Retinal Detachment | Toxic Effect of Silicone | Glaucoma Due to Silicon Oil

Croatia
Eye Therapies, LLC
ORA, Inc.

Completed

A Single-Center, Randomized, Double-Masked, Placebo and Active Controlled, Dose-Ranging Evaluation of the Duration of Action of Brimonidine Tartrate Ophthalmic Solution in the Control of Ocular Redness Induced by Conjunctival Allergen Challenge (CAC)

Allergic Conjunctivitis

United States
Allergan

Completed

24-hour IOP-lowering Effect of Brimonidine 0.1%

Ocular Hypertension | Open-angle Glaucoma

United States
Seoul National University Hospital

Unknown

Efficacy and Safety Study of Combigan and 0.5% Timoptic in Normal Tension Glaucoma

Normal Tension Glaucoma

Korea, Republic of
Allergan

Completed

An Evaluation of the Fixed Combination Brimonidine Tartrate 0.2%/ Timolol Maleate 0.5% to Latanoprost 0.005% in Glaucoma or Ocular Hypertension Subjects

Ocular Hypertension | Glaucoma

United States
Universidade Federal do Paraná

Unknown

Intraocular Pressure Control After Anterior Segment Laser - Comparison Between 2 Drugs

Glaucoma, Narrow Angle

Brazil
Allergan

Completed

Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension

United States

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