Clinical Trials Sponsored by BlackThorn Therapeutics, Inc.

Total 2989 results

Cardiol Therapeutics Inc.

Active, not recruiting

Impact of CardiolRxTM on Recurrent Pericarditis (MAvERIC-Pilot)

Recurrent Pericarditis

United States
Jounce Therapeutics, Inc.

Terminated

Study of PD-1 Inhibitor JTX-4014 Alone and in Combination With Vopratelimab in Biomarker-selected Subjects With Metastatic NSCLC After One Prior Platinum-containing Regimen (SELECT)

NSCLC

Latvia, Bosnia and Herzegovina, Russian Federation, Romania, Turkey, Belarus, Bulgaria, Croatia, Hungary, Serbia, Slovakia, Ukraine, Georgia, Moldova, Republic of
Galera Therapeutics, Inc.

Terminated

Phase 2b Study of GC4711 in Combination With SBRT for Nonmetastatic Pancreatic Cancer

Unresectable Pancreatic Cancer | Borderline Resectable Pancreatic Cancer | SBRT

United States, France, United Kingdom, Canada
Click Therapeutics, Inc.

Completed

An Exploratory Study to Evaluate Attention Biases in Adults With Multiple Sclerosis, Breast Cancer, and Lung Cancer

Multiple Sclerosis | Breast Cancer | Lung Cancer

United States
Zydus Therapeutics Inc.

Active, not recruiting

Saroglitazar Magnesium for Treatment of Primary Biliary Cholangitis (EPICS-III)

Primary Biliary Cholangitis

United States, Argentina, Iceland, Turkey
Stoke Therapeutics, Inc

Enrolling by invitation

An Open-Label Extension Study of STK-001 for Patients With Dravet Syndrome

Dravet Syndrome

United States
Cognito Therapeutics, Inc.

Enrolling by invitation

Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015)

Cognitive Impairment | Alzheimer Disease | Mild Cognitive Impairment | Dementia Alzheimers | Dementia of Alzheimer Type | AD | Dementia, Mild | Dementia Moderate

United States
Cara Therapeutics, Inc.

Terminated

A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
TG Therapeutics, Inc.

Terminated

Ublituximab + TGR-1202 Compared to Obinutuzumab + Chlorambucil in Participants With Untreated and Previously Treated Chronic Lymphocytic Leukemia (UNITY-CLL)

Chronic Lymphocytic Leukemia

United States, Israel, Italy, Poland, Russian Federation, Spain, United Kingdom
Nurix Therapeutics, Inc.

Terminated

A Study of DeTIL-0255 in Adults With Advanced Malignancies

Cervical Cancer | Endometrial Cancer | Platinum-resistant Ovarian Cancer

United States
TenNor Therapeutics Inc.

Completed

Phase 1, Single-Dose and Multiple-Dose Continuous Intravenous Infusions of TNP-2092 for Injection in Healthy Chinese Participants

Acute Bacterial Skin and Skin Structure Infection (ABSSSI) | Prosthetic Joints Infection (PJI)

China
Travere Therapeutics, Inc.

Active, not recruiting

Study of Sparsentan in Patients With Primary Focal Segmental Glomerulosclerosis (FSGS) (DUPLEX)

Focal Segmental Glomerulosclerosis

United States, Australia, Belgium, Croatia, Estonia, Germany, Hong Kong, Italy, Korea, Republic of, Poland, Portugal, Spain, Taiwan, United Kingdom, Argentina, Brazil, Canada, Czechia, Denmark, France, New Zealand, Sweden
Aclaris Therapeutics, Inc.

Terminated

Study of ATI-450 vs Placebo in Patients With Moderate to Severe Psoriatic Arthritis

Psoriatic Arthritis

United States, Poland
Eirion Therapeutics Inc.

Active, not recruiting

AI-09 In Subjects With Glabellar Lines, GL-101

Glabellar Frown Lines

United States
Atossa Therapeutics, Inc.

Active, not recruiting

Effect of Oral (Z)-Endoxifen in Premenopausal Women With Measurable Breast Density

Breast Density

Sweden
Aviceda Therapeutics, Inc.

Terminated

A Phase 2 Study of Intravitreal AVD-104 in Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema

United States
Mirati Therapeutics Inc.

Terminated

Phase 2 Study of Glesatinib, Sitravatinib or Mocetinostat in Combination With Nivolumab in Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States
Chinook Therapeutics, Inc.

Active, not recruiting

Safety and Tolerability of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy (IgAN)

IgA Nephropathy

Korea, Republic of, United States, United Kingdom
Poseida Therapeutics, Inc.

Active, not recruiting

P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)

Neoplasms | Neoplasms by Histologic Type | Urogenital Neoplasms | Neoplasms by Site | Genital Neoplasms, Male | Prostatic Neoplasms | Adenoid Cystic Carcinoma | Mucoepidermoid Carcinoma | Prostate Cancer | Prostatic Neoplasms, Castration-Resistant | Metastatic Castration-resistant Prostate Cancer | Neoplasms... and other conditions

United States
Sarepta Therapeutics, Inc.

Active, not recruiting

A Study to Compare Safety and Efficacy of a High Dose of Eteplirsen in Participants With Duchenne Muscular Dystrophy (DMD) (MIS51ON)

Muscular Dystrophy, Duchenne

United States, Korea, Republic of, India, Slovenia, Turkey, United Kingdom, Germany, Switzerland, Spain, Czechia, France, Serbia, Taiwan, Netherlands, Mexico, Colombia, Denmark, New Zealand, Norway, Greece, Hungary, Ireland, Italy, Jo... and more
Carisma Therapeutics Inc

Active, not recruiting

CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors

Adenocarcinoma | Stomach Neoplasms | Cancer | Breast Cancer | Head and Neck Cancer | Carcinoma, Hepatocellular | Colorectal Cancer | Pancreatic Cancer | Ovarian Neoplasms | Carcinoma, Ovarian Epithelial | Carcinoma, Transitional Cell | Breast Neoplasm | Prostate Cancer | Bile Duct Cancer | Bladder Cancer | Endometrial Cancer and other conditions

United States
ImmuneOncia Therapeutics Inc.

Active, not recruiting

A Study of IMC-001 in Subjects With Relapsed or Refractory Extranodal NK/T Cell Lymphoma, Nasal Type

Extranodal NK/T-cell Lymphoma, Nasal Type | Extranodal NK/T-cell Lymphoma

Korea, Republic of
Dermaliq Therapeutics, Inc.

Completed

Safety and Efficacy Study of Topical DLQ01 in the Treatment of Androgenetic Alopecia (AGA) in Men

Androgenetic Alopecia

Australia
TG Therapeutics, Inc.

Completed

Study of TG-1801 in Subjects With B-Cell Lymphoma

B-Cell Lymphoma

Australia
Candel Therapeutics, Inc.

Completed

Phase 2a Study of CAN-2409 With Standard Radiation Therapy for Malignant Glioma (BrTK02)

Glioblastoma Multiforme | High Grade Glioma | Malignant Glioma | Anaplastic Astrocytoma

United States
Axsome Therapeutics, Inc.

Enrolling by invitation

A Study to Assess the Long-term Safety and Efficacy of AXS-05 in Subjects With Alzheimer's Disease Agitation

Alzheimer Disease | Agitation in Patients With Dementia of the Alzheimer's Type | Agitation, Psychomotor

United States, Canada
Outlook Therapeutics, Inc.

Active, not recruiting

A 3-month Study to Compare the Safety of ONS-5010 in Vials Versus Pre-filled Syringe in Subjects With Visual Impairment Due to Retinal Disorders (NORSE SEVEN)

Age-Related Macular Degeneration | Diabetic Macular Edema | Wet Macular Degeneration | Neovascular Age-related Macular Degeneration | BRVO - Branch Retinal Vein Occlusion

United States
Electra Therapeutics Inc.

Completed

Evaluation of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ELA026 in Single and Multiple Doses in Healthy Volunteers

Healthy Volunteers

United States, Austria
Stemline Therapeutics, Inc.

Completed

Safety and Efficacy Study of SL-701, a Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblastoma Multiforme

Glioblastoma Multiforme | Adult Brain Glioblastoma

United States
Immunomic Therapeutics, Inc.

Active, not recruiting

Study to Evaluate the Safety, Tolerability, Immunogenicity and Preliminary Efficacy of ITI-1001 In Patients With Newly Diagnosed Glioblastoma (GBM)

Glioblastoma

United States
AsclepiX Therapeutics, Inc.

Terminated

Safety and Bioactivity of AXT107 in Subjects With Diabetic Macular Edema (CONGO)

Diabetic Macular Edema (DME)

United States
Kartos Therapeutics, Inc.

Terminated

An Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 When Administered Alone and in Combination With Low-Dose Cytarabine (LDAC) or Decitabine in Patients With Acute Myeloid Leukemia (AML)

Relapsed or Refractory Acute Myeloid Leukemia (AML) | Acute Myeloid Leukemia (AML), Secondary to Myeloproliferative Neoplasms (MPN)

United States, Spain, Korea, Republic of, Belgium, United Kingdom, Hungary, France, Germany, Israel, Australia, Italy, Poland
Cellphire Therapeutics, Inc.

No longer available

Thrombosomes for Expanded Access Use

Bleeding
AN2 Therapeutics, Inc

Completed

Phase 1 Study of Epetraborole Tablets

Healthy Volunteers

Australia
Mirati Therapeutics Inc.

Completed

A PK Study to Assess the Drug-drug Interaction of a Strong CYP2C8 Inhibitor on Adagrasib

Healthy Adults

United States
G1 Therapeutics, Inc.

Completed

Trilaciclib, a CDK4/6 Inhibitor, in Patients With Early-Stage Triple Negative Breast Cancer

Breast Cancer | Triple Negative Breast Cancer

United States
Actuate Therapeutics Inc.

Active, not recruiting

9-ING-41 in Patients With Advanced Cancers

Sarcoma | Cancer | Breast Neoplasms | Neoplasm Metastasis | Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Bone Cancer | Malignant Glioma | Bone Metastases | Pancreas Cancer | Renal Cancer | Refractory Non-Hodgkin Lymphoma | Bone Neoplasm | Neoplasm, Breast | Refractory Cancer | Refractory Neoplasm | Resistant... and other conditions

United States, Belgium, Canada, Spain, France, Netherlands, Portugal
Click Therapeutics, Inc.

Active, not recruiting

An Exploratory Study to Evaluate a Digital Intervention to Disrupt Scratching in Atopic Dermatitis and Psoriasis

Psoriasis | Atopic Dermatitis

United States
Osteal Therapeutics, Inc.

Active, not recruiting

A Second Trial of the Abbreviated Protocol Two-Stage Exchange (Apex-2)

Prosthetic-joint Infection

United States
Design Therapeutics, Inc.

Completed

Study to Evaluate Multiple Ascending Dose and Multi-Dose of DT-216 in Adult Patients With Friedreich Ataxia

Friedreich Ataxia

United States
Avalo Therapeutics, Inc.

Completed

Phase 1b Study of AEVI-007 in Subjects With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma

United States
RAPT Therapeutics, Inc.

Suspended

Phase 2 Study to Evaluate RPT193 in Adults With Moderate to Severe T2-high Asthma

Asthma

United States, Bulgaria, Czechia, Poland
Kirilys Therapeutics Inc.

Active, not recruiting

Study of ASN004 in Patients With Advanced Solid Tumors (ASN004)

Solid Tumor

United States
CuraSen Therapeutics, Inc.

Completed

A Study of CST-2032 and CST-107 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's or Alzheimer's Disease

Dementia | Mild Cognitive Impairment

United States, New Zealand
Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (KIND-1)

Pruritus | Atopic Dermatitis

United States
Atsena Therapeutics Inc.

Active, not recruiting

Study of Subretinally Injected ATSN-101 Administered in Patients With Leber Congenital Amaurosis Caused by Biallelic Mutations in GUCY2D

Leber Congenital Amaurosis | LCA | LCA1

United States
Pliant Therapeutics, Inc.

Completed

Imaging Evaluation of PLN-74809 in Participants With IPF (PLN-74809) (PLN-74809)

Idiopathic Pulmonary Fibrosis

United States
Neuraptive Therapeutics Inc.

Temporarily not available

NTX-001 to Repair Peripheral Nerve Transection(s)

Peripheral Nerve Transections, Acute or Planned in Upper Extremity and Facial Nerves

United States
Neuraptive Therapeutics Inc.

Active, not recruiting

Safety and Efficacy of NTX-001 Compared to SOC in Acute Single Peripheral Nerve Injuries

Peripheral Nerve Injuries

United States
Fortis Therapeutics, Inc.

Completed

A Phase 1 Study of FOR46 in Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Prostate Cancer Metastatic

United States

Clinical Trials Sponsored by BlackThorn Therapeutics, Inc.

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