Clinical Trials Sponsored by Merck Europe B.V.

Total 247 results

Maatschap Cardiologie Zwolle
Terumo Europe N.V.

Completed

Complex Large-bore Radial Percutaneous Coronary Intervention (PCI) Trial (Color)

Complex Coronary Lesions

Netherlands, Belgium, Germany, Switzerland, United Kingdom
Terumo Europe N.V.
Terumo Medical Corporation

Recruiting

Post-market Clinical Investigation of the Angio-Seal™ VIP VCD (ANGIO-SEAL CLOSE)

Peripheral Vascular Disease | Hemostasis | Vascular Closure | Femoral Artery | Endovascular Procedure

France, Germany, Netherlands
Astellas Pharma Europe B.V.
Cubist Pharmaceuticals LLC

Completed

A Study to Assess the Effects of Multiple Doses of Fidaxomicin on a Single Dose of Rosuvastatin in Healthy Male Subjects

Healthy Subjects | Drug-Drug Interaction (DDI) | Intestinal Absorption | Pharmacokinetics of Rosuvastatin | Pharmacokinetics of Fidaxomicin

Germany
Astellas Pharma Europe B.V.
Veeda Clinical Research

Completed

Observational, Non-interventional, Non Comparative Real Life Data Collection of Depo-Eligard® 7.5 mg, 22.5 mg and 45 mg in Male Prostate Cancer Patients (TREMODI)

Prostate Cancer

Belgium
Royal Free Hospital NHS Foundation Trust
KCI Europe Holding B.V.

Terminated

Negative Pressure Wound Therapy With Instillation for Treatment of Hidradenitis Suppurativa (HIDRA)

Hidradenitis Suppurativa

United Kingdom
Merck KGaA, Darmstadt, Germany
Merck N.V.-S.A., Belgium

Terminated

An Observational Study to Compare the Dose of Gonal-fTM FbM Prescribed by the Doctor With the Recommendation of the Dose Calculator Consort and to Evaluate the Ease of Use of Pre-filled Pen of Gonal-fTM FbM Pen

Multifollicular Stimulation

Belgium
Astellas Pharma Europe B.V.
Veeda Clinical Research

Completed

Treatment of Symptoms in Male Patients With Lower Urinary Tract Symptoms (LUTS) Predominant Storage Symptoms (Overactive Bladder Syndrome) (VENICE)

Lower Urinary Tract Predominant Storage Symptoms

Belgium
Technische Universität Dresden
Kaneka Pharma Europe N.V.

Recruiting

Effect of Lipoprotein(a) Elimination by Lipoprotein Apheresis on Cardiovascular Outcomes (MultiSELECt)

Lipoprotein Types--Lp System Lp(A) Hyperlipoproteinemia

Germany
Merck KGaA, Darmstadt, Germany
Merck S.A. de C.V., Mexico

Completed

Neuropathic Pain Management (M-F0434)

Diabetic Neuropathies | Polyneuropathies

Mexico
Aplagon Oy
TRACER Europe BV

Recruiting

Safety, Tolerability, and Biodistribution of [89Zr]Zr-DFO-APAC in Subjects With PAOD/CLI and Healthy Volunteers (Acronyms: 89Zr = Zirconium-89, DFO = Desferrioxamine, APAC = AntiPlatelet AntiCoagulant, PET/CT = Positron Emission Tomography/Computed Tomography) (CHASE)

Peripheral Arterial Occlusive Disease | Critical Limb Ischemia

Netherlands
ECRI bv
University of Bern; European Cardiovascular Research Center; Terumo Medical Corporation and other collaborators

Completed

Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation With an Abbreviated Versus Prolonged DAPT Regimen (MASTER DAPT)

Coronary Artery Disease | PCI | High Bleeding Risk

Netherlands, France, United Kingdom, Australia, Singapore, Japan, Italy, Poland, Spain, Switzerland, Israel, Argentina, Austria, Bahrain, Bangladesh, Belgium, Bulgaria, Czechia, Denmark, Estonia, Germany, Hungary, India, Korea, Republic... and more
Merck KGaA, Darmstadt, Germany
Merck S.A. de C.V., Mexico

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in Mexico (ECOS MEX)

Growth Disorders

Mexico
Merck KGaA, Darmstadt, Germany
Merck S.A. de C.V., Mexico

Completed

Efficacy and Safety of Gabapentin/B-complex Versus Pregabalin in Diabetic Peripheral Neuropathy Pain Management

Diabetic Peripheral Neuropathic Pain

Mexico
Athena Institute, Netherlands
Yakult Europe BV

Unknown

Improving Bowel Habits of Elderly With Probiotics and Non-probiotics

Constipation | Diarrhea
AvenCell Europe GmbH
Allucent (NL) BV

Recruiting

Dose-escalating Trial With Allo-RevCAR01-T Cells in Combination With CD123 Target Module (R-TM123) for Participants With Selected Hematologic Malignancies Positive for CD123

Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory

Germany, Netherlands
Astellas Pharma Europe B.V.
World Health Information Science Consultants, LLC

Completed

Short and Long-term Safety of Micafungin and Other Parenteral Antifungal Agents (MYCOS)

Systemic Fungal Infections

United States
National Centre of Ophthalmology named after academician...
Aeon Astron Europe B.V.

Completed

Trabeculectomy With Ologen Collagen Implant vs Trabeculectomy With Provisc in Steroid Induced Glaucoma

Steroid Induced Glaucoma

Azerbaijan
National Centre of Ophthalmology named after academician...
Aeon Astron Europe B.V.

Unknown

Combined Trab+Trab Versus Combined Trab+Trab With Subconjunctival Implantation of Ologen for Primary Congenital Glaucoma

Congenital Glaucoma

Azerbaijan
Aarhus University Hospital Skejby
Terumo Europe N.V.; Johnson & Johnson

Completed

SORT-OUT V - Randomised Clinical Comparative Study of the Nobori and the Cypher Stent. (SORT-OUT V)

Coronary Artery Disease | Angina Pectoris

Denmark
Hannover Medical School
Terumo Europe N.V.; Städtisches Klinikum Braunschweig

Unknown

Incidence of Acute Cerebrovascular Events Using Either Minimized or Standard Cardiopulmonary Bypass Circuit (ROCsafeTM)

Coronary Artery Disease | Embolism, Air | Intracranial Embolism | Acute Cerebrovascular Accident

Germany
Princess Maxima Center for Pediatric Oncology
University of Milano Bicocca; Amgen Europe B.V

Recruiting

Interfant-21 Treatment Protocol for Infants Under 1 Year With KMT2A-rearranged ALL or Mixed Phenotype Acute Leukemia (Interfant-21)

Acute Lymphoblastic Leukemia | Mixed Phenotype Acute Leukemia

Norway, Finland, Denmark, Netherlands, Hungary, Argentina, Australia, Austria, Belgium, Czechia, France, Germany, Ireland, Italy, Japan, Portugal, Saudi Arabia, Sweden
ExThera Medical Europe BV
University Hospital, Essen

Not yet recruiting

Reduction of BK Viremia in Kidney Transplant Patients (CP026)

Kidney Diseases | Kidney Transplant Infection | Kidney Transplant; Complications

Germany
MCM Vaccines B.V.
Merck Sharp & Dohme LLC; Sanofi Pasteur, a Sanofi Company

Completed

Long-term Persistence of Hepatitis B and Pertussis Antibody Responses in Healthy 4 to 5 Year Old Children Previously Vaccinated With Vaxelis® or INFANRIX® Hexa (V419-012)

Hepatitis B | Pertussis
MCM Vaccines B.V.
Merck Sharp & Dohme LLC; Sanofi Pasteur, a Sanofi Company

Completed

Spanish Mixed HEXA/PENTA/HEXA Schedule (V419-010)

Virus Diseases | Bacterial Infections | Neisseria Meningitidis
Aeon Astron Europe B.V.
The New York Eye & Ear Infirmary; Robert Ritch, MD, LLC.

Completed

Comparative Study of Ologen Collagen Matrix Versus Mitomycin-C in Glaucoma Filtering Surgery (MCToCM)

Glaucoma

United States
Bayer
Novartis Pharmaceuticals; Biogen; EPID Research; Merck Serono Europe Ltd

Completed

EPID Multiple Sclerosis Pregnancy Study

Multiple Sclerosis

Finland
Merck KGaA, Darmstadt, Germany
Merck Serono GmbH, Germany; Merck B.V., Netherlands; Merck A.E., Greece; Merck... and other collaborators

Completed

PERgoveriS In Stratified Treatment for Assisted Reproductive Technique (PERSIST)

Assisted Reproductive Techniques | Reproductive Technology, Assisted

Italy, Russian Federation, United Kingdom, Germany, Poland, Finland, Slovakia, Netherlands, Denmark, France, Greece
European Society of Cutaneous Lupus Erythematosus...

Unknown

European Society of Cutaneous Lupus Erythematosus (EUSCLE)

Lupus Erythematosus, Systemic | Lupus Erythematosus, Cutaneous

Germany
European Society of Cutaneous Lupus Erythematosus...

Completed

Interdisciplinary Study Group of Lupus Erythematosus (ISGLE)

Cutaneous Lupus Erythematosus

Germany
Astellas Pharma Europe Ltd.
Merck Sharp & Dohme LLC

Completed

A Phase IIIB/IV Study to Compare the Efficacy of Vancomycin Therapy to Extended Duration of Fidaxomicin Therapy in the Clinical Cure of Clostridium Difficile Infection (CDI) in an Older Population (EXTEND)

Clostridium Difficile

Greece, Spain, Russian Federation, Denmark, Austria, Belgium, Croatia, Czechia, Finland, France, Germany, Hungary, Ireland, Italy, Poland, Portugal, Romania, Slovenia, Sweden, Switzerland, Turkey, United Kingdom
Acerta Pharma BV
Merck Sharp & Dohme LLC

Completed

Study of the Combination of Acalabrutinib (ACP-196) and Pembrolizumab in Advanced Head and Neck Squamous Cell Carcinoma (KEYNOTE147)

Squamous Cell Carcinoma of the Head and Neck

United States
Acerta Pharma BV
Merck Sharp & Dohme LLC

Completed

Study of the Combination of ACP-196 and Pembrolizumab in Subjects With Platinum Resistant Urothelial Bladder Cancer (KEYNOTE143)

Metastatic Urothelial Carcinoma

United States
Comenius University
Sanatórium of Dr. Guhr, n.o.; Kaneka Pharma Europe N.V.

Completed

Spa Rehabilitation, Antioxidant and Bioenergetic Supportive Treatment of Patients With Post-Covid-19 Syndrome (SpaCOVID)

COVID-19 Respiratory Infection

Slovakia
Acerta Pharma BV
Merck Sharp & Dohme LLC

Completed

ACP-196 Alone and in Combination With Pembrolizumab in Subjects With Advanced or Metastatic Pancreatic Cancer (KEYNOTE144)

Metastatic Pancreatic Cancer

United States
Acerta Pharma BV
Merck Sharp & Dohme LLC

Completed

Acalabrutinib (ACP-196) Alone and in Combination With Pembrolizumab in Ovarian Cancer (KEYNOTE191)

Ovarian Cancer

United States
Acerta Pharma BV
Merck Sharp & Dohme LLC

Active, not recruiting

ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies (KEYNOTE145)

Multiple Myeloma | Hodgkin Lymphoma | Waldenström Macroglobulinemia | Burkitt Lymphoma | Small Lymphocytic Lymphoma (SLL) | Hairy Cell Leukemia | CLL | Mantle Cell Lymphoma (MCL) | Follicular Lymphoma (FL) | Richter's Syndrome | Indolent Non Hodgkin Lymphoma | Marginal Zone Lymphomas | Mediastinal Large B Cell...

United States
Acerta Pharma BV
Merck Sharp & Dohme LLC

Completed

Pembrolizumab Alone and In Combination With Acalabrutinib (ACP-196) in Subjects With Advanced Non-small Cell Lung Cancer (KEYNOTE166)

Carcinoma, Non-Small-Cell Lung

United States
European Institute of Oncology
Merck Sharp & Dohme LLC

Recruiting

ECT-Pembrolizumab in Patients With Unresectable Melanoma With Superficial or Superficial and Visceral Metastases

Malignant Melanoma

Italy
G.V. (Sonny) Montgomery VA Medical Center
Merck Sharp & Dohme LLC

Completed

VBMI to Increase Treatment Completion With MK-MK-5172/MK-8742 Among Veterans With Active Substance Use Disorders Genotype 1 Chronic Hepatitis C (VBMI SUD/HCV)

Patient Adherence, Chronic Hepatitis C, Alcohol-related Disorders

United States
Terumo Europe N.V.
Universitaire Ziekenhuizen KU Leuven; Federation Francophone de Cancerologie...

Completed

LifePearl-Iri Pharmacokinetic Study

Metastatic Colorectal Cancer | mCRC

Belgium, Germany
University Medical Center Groningen
PRA Health Sciences; TRACER Europe BV

Recruiting

Anti-COVID19 VaccinaTion AKS-452 BOOSTER (ACT-BOOSTER Study) (ACT-BOOSTER)

COVID-19

Netherlands
ExThera Medical Europe BV
ExThera Medical Corporation; Vivantes Clinic Neukölln

Recruiting

Reduction of Pathogen Load From the Blood in Septic Patients With Suspected, Life-threatening Bloodstream Infection

Bloodstream Infection

France, Germany, Netherlands, Austria, Belgium, Italy, Poland, Spain, United Kingdom
ExThera Medical Europe BV
ExThera Medical Corporation; Vivantes Clinic Neukölln

Recruiting

Safety & Effectiveness Evaluation of Seraph 100 in Treatment of Pts With COVID-19 (CP022)

COVID-19

Spain, Germany
Skane University Hospital
The Swedish Research Council; Uppsala University Hospital; Falu Hospital; Gävle... and other collaborators

Completed

Vacuum Assisted Wound Closure (VAWC) and Mesh Mediated Fascial Traction

Fascial Closure | Open Abdomen

Sweden
University of Zurich
Stryker European Operations BV

Completed

Covers to Improve Esthetic Outcome After Surgery for Chronic Subdural Hematoma (CORRECT-SCAR)

Hematoma, Subdural, Chronic | Hematoma, Subdural, Intracranial | Haematoma;Subdural;Traumatic

Switzerland
University College, London
Stryker European Operations BV

Recruiting

Mako Functionally Aligned Total Knee Arthroplasty vs Mako Mechanically Aligned Total Knee Arthroplasty

Osteoarthritis | Osteo Arthritis Knee | Surgery

United Kingdom
University of Giessen
Deutsche Krebshilfe e.V., Bonn (Germany); Euronet Worldwide

Active, not recruiting

Second International Inter-Group Study for Classical Hodgkin Lymphoma in Children and Adolescents

Classical Hodgkin Lymphoma

United Kingdom, Australia, Austria, Belgium, Czechia, Denmark, France, Germany, Ireland, Israel, Italy, Netherlands, New Zealand, Norway, Poland, Slovakia, Spain, Sweden, Switzerland
Wageningen University and Research
Amsterdam UMC, location VUmc; Fonterra (Europe) Cooperatie U.A.; Carezzo B.V.; Hogeschool...

Completed

Increase Protein Intake in Elderly

Markedly Reduced Food Intake

Netherlands
Maastricht University Medical Center
Stryker European Operations BV

Unknown

RSA Study Using Two Types of Uncemented Acetabular Components and the Uncemented HA Coated Symax Stem (RSA)

Osteoarthritis

Netherlands
Terumo Europe N.V.
Federation Francophone de Cancerologie Digestive; Fundacion Clinic per a la...

Completed

LifePearl-Doxo Pharmacokinetic (PK) Study

HCC | Hepatocellular Carcinoma

Switzerland, Spain, Greece

Clinical Trials Sponsored by Merck Europe B.V.

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in France

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations