Clinical Trials Sponsored by World Heart Corporation

Total 268 results

Ottawa Heart Institute Research Corporation
AFP Innovation Fund

Recruiting

Effect of a Hybrid Rehabilitation Program on Walking, Quality of Life & Cardiovascular Risk in People With PAD (HY-PAD)

Peripheral Arterial Disease

Canada
Ottawa Heart Institute Research Corporation
University of Calgary

Recruiting

Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance (TITAN:SvS)

Ascending Aorta Aneurysm | Ascending Aortic Aneurysm Enlargement

United States, Canada
Ottawa Heart Institute Research Corporation
Toronto General Hospital

Active, not recruiting

Early Post Transplant Cardiac Allograft Vasculopathy (ECAV)

Cardiac Allograft Vasculopathy

Canada
Ottawa Heart Institute Research Corporation
Spartan Bioscience Inc.

Completed

ReAssessment of Anti-Platelet Therapy Using an InDividualized Strategy Based on GENetic Evaluation (RAPID GENE)

Acute Coronary Syndrome | Percutaneous Coronary Intervention | Stable Coronary Artery Disease

Canada
Ottawa Hospital Research Institute
Ottawa Heart Institute Research Corporation

Completed

Cardiac MRI for Metal on Metal Hip Resurfacing (CardiacMRI)

Cardiomyopathy

Canada
Lawson Health Research Institute
Ottawa Heart Institute Research Corporation

Terminated

Using IVR to Maintain ACS Patients on Best Practice Guidelines (IVR-ACS BPG)

Medication Adherence | Acute Coronary Syndrome

Canada
Ottawa Hospital Research Institute
Ottawa Heart Institute Research Corporation

Completed

Smoking Cessation With the Ottawa Model and SmartCard in Out-patient Respirology Clinic Setting (Quit&Win)

Smoking Cessation

Canada
Ottawa Heart Institute Research Corporation
Bristol-Myers Squibb; Sanofi

Completed

Trial of Clopidogrel After Surgery for Coronary Artery Disease (CASCADE Trial) (CASCADE)

Atherosclerosis

Canada
Ottawa Heart Institute Research Corporation
Roche Diagnostics; Genome Canada

Active, not recruiting

Biomarkers to Classify Heart Failure

Heart Failure

Canada
Ottawa Heart Institute Research Corporation
Ontario HIV Treatment Network

Completed

The Effects of Statin Therapy on Coronary Flow Reserve and Inflammatory Markers in HIV-Positive Patients

Human Immunodeficiency Virus (HIV) | Cardiovascular Disease (CVD)

Canada
Imperial College London
British Heart Foundation; Leducq Foundation; Celladon Corporation

Terminated

Investigation of the Safety and Feasibility of AAV1/SERCA2a Gene Transfer in Patients With Chronic Heart Failure (SERCA-LVAD)

Chronic Heart Failure | Patients That Have Received a Left Ventricular Assist Device

United Kingdom
University of Minnesota Physicians Heart at Fairview
Boston Scientific Corporation

Completed

Assessment of Appropriate ICD Implantation for Primary Prevention of Sudden Cardiac Death

Cardiomyopathies
Heart Rhythm Clinical and Research Solutions, LLC
Boston Scientific Corporation

Not yet recruiting

A Registry Based Collaborative to Measure Efficiency, Effectiveness, and Safety of Farapulse PFA Technology for AF (DISRUPT-AF)

Atrial Fibrillation

United States
University of British Columbia
Medtronic; Ottawa Heart Institute Research Corporation

Active, not recruiting

The Impact of "First-Line" Rhythm Therapy on AF Progression (PROGRESSIVE-AF)

Atrial Fibrillation

Canada
Boca Raton Regional Hospital
AstraZeneca; Ottawa Heart Institute Research Corporation

Completed

Ticagrelor Antiplatelet Therapy to Reduce Graft Events and Thrombosis (TARGET)

Saphenous Vein Graft Disease

United States, Canada
Midwest Heart Foundation
Boston Scientific Corporation; Medtronic; Abbott Medical Devices

Completed

Comparison of a MAGNET Protocol Versus "off-on" Protocol for Patients With Implantable Cardioverter Defibrillators (MAGNET)

Heart Failure | Arrhythmia | Sudden Cardiac Death

United States
Rigshospitalet, Denmark
Lundbeck Foundation; Danish Heart Foundation; Copenhagen Hospital Corporation

Unknown

Copenhagen Arterial Revascularization Randomized Patency and Outcome Trial (CARRPO)

Angina Pectoris | Ischemic Heart Disease | Coronary Arteriosclerosis

Denmark
Heart Rhythm Clinical and Research Solutions, LLC
Boston Scientific Corporation

Recruiting

Safety and Efficacy of Workflows of High Volume Single Operators in a LAAO Device Implant Procedural Day

Atrial Fibrillation

United States
Ottawa Heart Institute Research Corporation
Cardiac Arrhythmia Network of Canada

Terminated

Atrial Fibrillation Trial to Evade Recurrence: effectS of Hiit Before electrO-Cardioversion for 3-weeKs (AFTERSHOCK)

Persistent Atrial Fibrillation

Canada
University Hospital, Basel, Switzerland
Swiss Agency for Development and Cooperation (SDC); World Diabetes Foundation...

Recruiting

"Community-based, eHealth Supported Management of Cardiovascular Risk Factors by Lay Village Health Workers (ComBaCaL aHT TwiC 1 & ComBaCaL aHT TwiC 2)

Arterial Hypertension

Lesotho, Switzerland
Emory University
National Heart, Lung, and Blood Institute (NHLBI); Cerus Corporation

Recruiting

Red Blood Cell Survival in Sickle Cell Disease

Sickle Cell Disease

United States
Liverpool Heart and Chest Hospital NHS Foundation...
Boston Scientific Corporation

Recruiting

Left Atrial Arrhythmia Substrate Identification After Confirmed durABLE Pulmonary Vein Isolation (LAUDABLE)

Atrial Fibrillation | Persistent Atrial Fibrillation

United Kingdom
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

Resynchronization/Defibrillation for Ambulatory Heart Failure Trial in Patients With Permanent Atrial Fibrillation (RAFT-PermAF)

Atrial Fibrillation | Heart Disease | Congestive Heart Failure

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

Timing of Coronary Artery Bypass Surgery Among Patients With Acute Coronary Syndromes Initially on Ticagrelor (RAPID CABG)

Acute Coronary Syndrome

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

Rubidium-82 - An Alternative Radiopharmaceutical for Myocardial Imaging(Rb-ARMI) (Rb-ARMI)

Coronary Artery Disease

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

Canadian Study of Arterial Inflammation in Patients With Diabetes and Vascular Events: EvaluatioN of Colchicine (CADENCE)

Cardiovascular Diseases | Inflammation | Diabetes | Atherosclerosis

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

Rhythm Control - Catheter Ablation With or Without Anti-arrhythmic Drug Control of Maintaining Sinus Rhythm Versus Rate Control With Medical Therapy and/or Atrio-ventricular Junction Ablation and Pacemaker Treatment for Atrial Fibrillation (RAFT-AF)

Heart Failure | Atrial Fibrillation

Canada, Taiwan, Sweden, Brazil
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

A Pharmacodynamic Study of a Personalized Strategy for P2Y12 Inhibition Versus Ticagrelor in Reducing Ischemic and Bleeding Risk (RAPID MANAGE)

Acute Coronary Syndrome | Percutaneous Coronary Intervention

Canada
University Hospital, Basel, Switzerland
SolidarMed; Swiss Agency for Development and Cooperation (SDC); World Diabetes...

Recruiting

Community-based, eHealth Supported Type 2 Diabetes Care by Lay Village Health Workers in Rural Lesotho (ComBaCaL T2D)

Type 2 Diabetes Mellitus (T2D)

Lesotho, Switzerland
Ottawa Heart Institute Research Corporation
Bristol-Myers Squibb; Bayer; Boehringer Ingelheim; Heart and Stroke Foundation...

Completed

Strategy of Continued Versus Interrupted Novel Oral Anti-coagulant at Time of Device Surgery in Patients With Moderate to High Risk of Arterial Thromboembolic Events (BRUISECONTROL2)

Hematoma

Canada, Israel
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

MARINER Trial: Multiparametric Cardiac PET for CAV Surveillance After Heart Transplantation

Cardiac Allograft Vasculopathy

Canada
Ottawa Heart Institute Research Corporation
University of British Columbia; McGill University

Not yet recruiting

Patient Specific Ablation Strategy for Atrial Fibrillation (AWARE-2): A Randomized Clinical Trial (AWARE-2)

Atrial Fibrillation | Radiofrequency Catheter Ablation | Catheter Ablation

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

AERIAL Trial: Antiplatelet Therapy in Heart Transplantation

Cardiac Allograft Vasculopathy | Heart Transplant

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

Cardiac Sarcoidosis Randomized Trial (CHASM-CS-RCT)

Sarcoidosis | Cardiac Sarcoidosis

United States, Canada, United Kingdom, Japan
Peter Liu
Ottawa Heart Institute Research Corporation; Roche Diagnostics; Genome Canada

Recruiting

Biomarker Guided Discharge of Heart Failure Patients (RADAR)

Heart Failure; With Decompensation

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments (INITIATE)

Nicotine Dependence, Cigarettes | Nicotine Withdrawal

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Terminated

Ability of L-carnitine to Prevent Heart Damage in Breast Cancer Patients Receiving Anthracycline Chemotherapy

Heart Failure

Canada
Ottawa Heart Institute Research Corporation
The Ottawa Hospital; University of Ottawa

Terminated

Smoking Reduction: Testing a Novel Approach to Cessation in Primary Care Practice Settings

Smoking Cessation

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Terminated

Bridge or Continue Coumadin for Device Surgery Randomized Controlled Trial (BRUISECONTROL)

Hematoma

Canada, Brazil
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

A Study of 123I-CMICE-013 Radiopharmaceutical in Healthy Volunteers (CMICE)

Coronary Artery Disease

Canada
Laval University
Eli Lilly and Company; Cordis Corporation; Quebec Heart Institute

Completed

A Randomized Trial of Early Discharge After Trans-radial Stenting of Coronary Arteries in Acute MI (EASY-MI)

Myocardial Infarction | Ischemia

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Completed

PET and Recovery Following Revascularization (PARR 2)

Coronary Artery Disease | Ventricular Dysfunction, Left

Canada
University Hospital, Basel, Switzerland
SolidarMed; Swiss Agency for Development and Cooperation (SDC); World Diabetes...

Recruiting

Community-Based Chronic Disease Care in Rural Lesotho (ComBaCaL)

Non-communicable Diseases (NCDs)

Lesotho, Switzerland
Hamad Medical Corporation
Sidra Medical and Research Center; World Anti-Doping Agency; Anti-Doping Lab... and other collaborators

Unknown

Using DNA-Typing and Erythrocyte Microparticle Analysis to Detect Blood Doping (Transfusion)

Blood Disease | Blood Transfusion, Autologous | Blood Doping | Blood Transfusion, Homologous

Qatar
AusculSciences Canada Inc.
University of Calgary; Hamilton Health Sciences Corporation; Ottawa Heart Institute... and other collaborators

Suspended

Evaluation of the CAD-det System, a Novel Non-Invasive Acoustic Diagnostic for the Diagnosis of Coronary Artery Disease (CAD-det)

Coronary Artery Disease | Cardiovascular Disease

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR); Medtronic

Completed

Resynchronization/Defibrillation for Ambulatory Heart Failure Trial (RAFT)

Heart Failure, Congestive

Canada, Netherlands, Australia, Turkey, Denmark, Germany, Belgium
McMaster University
Hamilton Health Sciences Corporation; Heart and Stroke Foundation of Ontario

Completed

Hospital Versus Home Based Exercise in Patients With Chronic Stable Heart Failure (PEAK-HF)

Congestive Heart Failure

Canada
Hamilton Health Sciences Corporation
Heart and Stroke Foundation of Canada

Unknown

Evaluation of a Primary Care Based Heart Failure Management Program

Heart Failure

Canada
Hamilton Health Sciences Corporation
Heart and Stroke Foundation of Canada

Terminated

D-Dimer and IPG for Recurrent Thrombosis (DIRECT)

Deep Vein Thrombosis | Pulmonary Embolism

Canada, Italy
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI); Celgene Corporation

Completed

Vascular Inflammation in Psoriasis - Apremilast (VIP-A)

Cardiovascular Diseases | Psoriasis

United States

Clinical Trials Sponsored by World Heart Corporation

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CROs in Togo

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