Search clinical trials for: Anti-Infective Agents, Local

Total 114545 results

Mayo Clinic

Recruiting

Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8

United States
Centre Hospitalier Universitaire Dijon

Not yet recruiting

Investigate the Efficacy of Chemotherapy in Patients With Positive ctDNA After Surgery and Adjuvant Chemotherapy for a Stage III Colorectal Cancer (CIRCULATE PAC)

Colon or Upper Rectum Adenocarcinoma

France
Ain Shams University

Recruiting

Effect of Chlorhexidine Versus Alcohol on Infections in Neonates

Neonatal Infection

Egypt
Nationwide Children's Hospital
Children's Hospital of Philadelphia; Boston Children's Hospital; Emory University and other collaborators

Recruiting

Improving Status Epilepticus Treatment Times (QuITT-SE)

Status Epilepticus

United States
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

A Real-world Study of Trifluridine/Tipiracil Containing Regimen for the Treatment of Patients With mCRC (REFLECT Study)

Metastatic Colorectal Cancer
Fudan University
Shanxi Province Cancer Hospital; Inner Mongolia Cancer Hospital Affiliated...

Recruiting

A Retrospective and Prospective Real-world Study of Molecular Typing in the Treatment of Advanced Thyroid Cancer

Advanced Thyroid Cancer Patients Who Received Target Therapy

China
University of Minnesota

Recruiting

Prophylactic Antibiotics in Cystectomy With Diversion

Muscle-Invasive Bladder Carcinoma | Radical Cystectomy | Ileal Conduit | Neobladder Diversion

United States
Zhongda Hospital

Recruiting

DEB-TACE With Visualable Microspheres Versus PVA Microspheres for HCC

Hepatocellular Carcinoma

China
University Hospital, Strasbourg, France

Recruiting

Interest of High-dose Gentamicin Cement Associated With Clindamycin in Changes of Hip and Knee Prostheses (HKP)

Hip or Knee Replacement

France
Universidade Federal do Para

Not yet recruiting

Pregabalin Gel in Reducing Post-operative Tooth Sensitivity Surgery Caused by Bleaching With 35% Hydrogen Peroxide

Tooth Bleaching | Sensitivity, Tooth

Brazil
University of Washington
Breast Cancer Research Foundation

Not yet recruiting

Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic HER2-Negative Breast Carcinoma | Metastatic Hormone Receptor-Positive Breast Carcinoma | Locally Advanced Unresectable HER2-Negative Breast Carcinoma | Locally Advanced Unresectable Hormone Receptor-Positive...

United States
Sun Yat-sen University

Not yet recruiting

The Effect of Sodium Fluoride Application on the Prevention of Radiation Caries in NPC Patients

Sodium Fluoride
University of Portsmouth

Not yet recruiting

The Effect of Chlorhexidine on the Oral Microbiome and Saliva in Dental Erosion

Dental Erosion

United Kingdom
National Cancer Institute (NCI)

Recruiting

Comparing the Combination of Selinexor-Daratumumab-Velcade-Dexamethasone (Dara-SVD) With the Usual Treatment (Dara-RVD) for High-Risk Newly Diagnosed Multiple Myeloma

Multiple Myeloma

United States
Xijing Hospital of Digestive Diseases

Recruiting

Standard or Short-course Vonoprazan Non-bismuth Triple Therapy or High-dose Dual Therapy Versus Rabeprazole-bismuth Quadruple Therapy for Primary Helicobacter Pylori Eradication

the Eradication Rates of Helicobacter Pylori

China
Yongquan Shi

Recruiting

Helicobacter Rescue Therapy With Vonorazon and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy

Gastritis Dyspepsia Helicobacter Pylori Infection Gastric Cancer Peptic Ulcer

China
David Clinkard
Queen's University

Recruiting

Genicular Artery Embolization vs Nerve Ablation Intervention (GENI) for Knee Osteoarthritis

Knee Osteoarthritis

Canada
Prof. Patrick Petignat
Dschang District Hospital

Recruiting

Home-based Cervical Cancer Screening Project (CASAHO)

Cervical Cancer

Cameroon
UNC Lineberger Comprehensive Cancer Center
Gilead Sciences

Recruiting

Artesunate Pessaries (Vaginal Inserts) for Cervical Precancer in Kenya

Precancerous Conditions | Cervix Cancer | Cervical Precancer | Cervix Neoplasm

Kenya
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Safety of Empliciti® (Elotuzumab) When Treating Patients With Multiple Myeloma in Taiwan

Relapsed or Refractory Multiple Myeloma

Taiwan
Chinese University of Hong Kong

Recruiting

Upfront EUS CGN/CPN vs Conventional Step up Approach for Inoperable Painful Pancreatic Cancer

Pancreatic Cancer Non-resectable | Pain Cancer | Tumor Pancreas

Hong Kong
Daiichi Sankyo
Merck Sharp & Dohme LLC

Recruiting

A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Solid Cancer

Japan, China, Taiwan
Tanta University

Recruiting

Evaluation of Possible Safety and Efficacy of Fenofibrate in the Prophylaxis of Doxorubicin Induced Cardiotoxicity in Breast Cancer Patients

Breast Cancer Stage 2 and 3

Egypt
Assiut University

Not yet recruiting

Recurrence in Patients With Differentiated Thyroid Cancer

Differentiated Thyroid Cancer
Centre Hospitalier Universitaire de Nīmes
Institut du Cancer de Montpellier - Val d'Aurelle

Not yet recruiting

Prognostic Role of Inhibitor of Apoptosis Protein Overexpression on Recurrence Rate in Cervical Cancer (EPIcol)

Cancer of Cervix | Apoptosis
Massachusetts General Hospital
Foundation Medicine

Recruiting

Use of Serial Plasma NGS as a New Efficacy Metric to Guide Immunotherapy Treatment Discontinuation

Melanoma | Non-small Cell Lung Cancer

United States
University of Washington
Novartis; Institute for Prostate Cancer Research (IPCR)

Not yet recruiting

Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Neoadjuvant Pyrotinib Versus Placebo Combined With Chemotherapy in HR-positive and HER2-low Early Breast Cancer

Early-stage Breast Cancer | Breast Cancer Invasive | HER2 Low Breast Carcinoma | Hormone-receptor-positive Breast Cancer

China
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Safety, Tolerability, Drug Levels, Food, Formulation, and pH Effects on Relative Absorption of BMS-986465 and Its Active Derivative BMS-986464 in Healthy Participants

Healthy Participants

United States
Lauren Whitehurst
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Ohio State University

Recruiting

The Effects of Sex Hormones and Alcohol on Sleep

Alcohol Use Disorder

United States
Xi'an Xintong Pharmaceutical Research Co.,Ltd.
The First Hospital of Jilin University

Recruiting

Treatment of MB07133 Plus Sintilimab in Patients With Hepatocellular Carcinoma (MB07133)

Efficacy | Safety Issues | MTD

China
Assiut University

Not yet recruiting

Differentiated Thyroid Cancer Patients Treated With Different Doses of Radioactive Iodine.

Thyroid Cancer
People's Hospital of Zhengzhou University

Recruiting

Factors on Therapeutic Drug Monitoring and Safety of Voriconazole in Critically Ill Elderly Patients

Invasive Fungal Infection

China
Merck Sharp & Dohme LLC
Orion Corporation, Orion Pharma

Recruiting

A Study of Opevesostat (MK-5684) in China Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC) (MK-5684-001)

Prostatic Neoplasms | Metastatic Castration-Resistant Prostate Cancer

China
Mongolian National University of Medical Sciences
Mongolian National Cancer Center

Recruiting

Interferon Alpha Therapy for Cervical CINI and HPV Infection

HPV Infection | Cervical Dysplasia

Mongolia
Universidad Simón Bolívar

Not yet recruiting

Intraoperative Autonomic Neural Blockade (ANB)

Pain, Postoperative | Analgesia | Opioid Use | Nausea, Postoperative | Vomiting, Postoperative
Tanta University

Recruiting

Sulfasalazine in Patients With Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

Egypt
Leciel Bono

Recruiting

Hand Sanitizer Use for Herpes Simplex Virus-1

HSV-1 | Herpes Simplex Labialis | Virus | Herpes Simplex 1

United States
Emory University
National Cancer Institute (NCI)

Not yet recruiting

Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial

Meningioma | Low Grade Glioma | Malignant Brain Neoplasm | Malignant Brain Glioma

United States
Zhejiang Cancer Hospital

Recruiting

Dalpiciclib Combination With Fulvestrant and Compound Gossyfol Acetate Tablets in Women With CDK4/6 Inhibitor-refractory HR-positive HER-2 Negtive Metastatic Breast Cancer: a Phase 2 Clinical Trial.

Advanced HR-positive and HER2-negative Breast Cancer; CDK4/6 Inhibitor Treatment Failed

China
Qassim University
Al-Azhar University

Recruiting

Different Modalities of Management of Odontogenic Keratocysts (OKCs)

Odontogenic Cysts

Saudi Arabia
Merck Sharp & Dohme LLC
GOG Foundation; European Network for Gynaecological Oncological Trial groups(ENGOT)

Recruiting

Sacituzumab Tirumotecan (MK-2870) in Post Platinum and Post Immunotherapy Endometrial Cancer (MK-2870-005)

Endometrial Cancer

Poland, Canada, Australia, Israel, Korea, Republic of, United States, Spain, Chile, France, Puerto Rico, Greece, Netherlands, Norway, Singapore, Switzerland, Argentina, Austria, Belgium, Czechia, Denmark, Finland, Malaysia, Sweden, Italy and more
AstraZeneca

Not yet recruiting

NIS Study Determining Prevalence of HER2-low in Metastatic Breast Cancer Patients (iRetroBC)

HER2-negative
Hamilton Health Sciences Corporation
McMaster University; Ontario Clinical Oncology Group (OCOG)

Recruiting

Infection Prophylaxis in Total Joint Replacement (PREVENT-iT)

Periprosthetic Joint Infection

Canada
National Cancer Institute (NCI)

Recruiting

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Malignant Female Reproductive System Neoplasm | Recurrent Malignant Female Reproductive System Neoplasm

United States
University of Iowa
Fabtech Systems

Not yet recruiting

The Effects of Heel Distraction Height on Foot Loading With Carbon Fiber Custom Dynamic Orthoses (CDODistract)

Traumatic Lower Limb Injury
University of Iowa

Recruiting

Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff (CuffForce)

Healthy

United States
Northeastern University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Recruiting

Multi-Component Breath Alcohol Intervention (BAMTECH)

Alcohol Drinking | Drinking Behavior | Alcohol Use

United States
Bristol-Myers Squibb

Recruiting

Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) (AURORA-HFpEF)

Heart Failure

United States, Spain, Canada, Italy, Poland
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Phase I Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes as Neoadjuvant Therapy for HER2-Negative Breast Cancer

Breast Neoplasms

China

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