Search clinical trials for: Early Manifest

Total 47414 results

The University of Texas Health Science Center,...

Suspended

Relationship Between Delayed Cord Clamping at Birth and Neonatal Bilirubin Levels in Parturients With a Prior Child Requiring Therapy for Neonatal Jaundice

Hyperbilirubinemia, Neonatal | Jaundice, Neonatal

United States
Umraniye Education and Research Hospital

Active, not recruiting

The Effect of Sedoanalgesia and General Anaesthesia on Early Neurological Recovery in Acute Ischaemic Stroke Patients Undergoing Endovascular Thrombectomy

Ischemic Stroke | Anesthesia | Neurologic Symptoms

Turkey
Teachers College, Columbia University

Active, not recruiting

Promoting Physical Activity Engagement for People With Early-stage Cerebellar Ataxia (EngageAtaxia)

Cerebellar Ataxia

United States
RTI International
University of North Carolina, Chapel Hill

Enrolling by invitation

Parent and Infant Inter(X)Action Intervention (PIXI)

Tuberous Sclerosis | Down Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Rett Syndrome | Turner Syndrome | Williams Syndrome | Angelman Syndrome | Chromosome 22q11.2 Deletion Syndrome | Klinefelter Syndrome | Phelan-McDermid Syndrome | Dup15Q Syndrome | Smith Magenis Syndrome

United States
Women's Hospital HUS

Completed

Spinal Fentanyl or Epidural Analgesia in the Early First Phase of Induced Labor

Labor Pain | Induced; Birth

Finland
Merz Therapeutics GmbH

Completed

Validity and Inter-rater Reliability for Early Recognition of Spasticity Using the Decision Tree Tool (I-REFER)

Post-stroke Spasticity

Austria
Synchron Medical, Inc.

Active, not recruiting

COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis

Paralysis | Amyotrophic Lateral Sclerosis | Muscular Dystrophies | Spinal Cord Injuries | Neurologic Disorder | Spinal Muscular Atrophy | Cervical Spinal Cord Injury | Stroke, Lacunar | Paralysis; Stroke | Stroke Brainstem | Tetraplegic; Paralysis | Quadriplegia/Tetraplegia

United States
Kanecia Obie Zimmerman

Completed

Single Dose IV Methadone for Post-Op Pain (MTH02)

Pain, Postoperative

United States
Washington University School of Medicine

Enrolling by invitation

I-Tracking Neurodegeneration in Early Wolfram Syndrome (I-TRACK)

Wolfram Syndrome

United States
Cochlear
EVAMED

Completed

Factors Affecting Early Progress of Cochlear Implant Outcomes in Adults (PROGRESS)

Sensorineural Hearing Loss, Bilateral

France
Radboud University Medical Center

Completed

Early Postoperative Pain and 30-day Complications Following Major Abdominal Surgery: an Observational Study

Postoperative Complications | Postoperative Pain | Acute Pain | Surgery--Complications | Infectious Complications

Netherlands
RTI International
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Early Check: Expanded Screening in Newborns

Primary Hyperoxaluria Type 3 | Diabetes Mellitus | Hemophilia A | Hemophilia B | Hereditary Fructose Intolerance | Cystic Fibrosis | Factor VII Deficiency | Phenylketonurias | Sickle Cell Disease | Dravet Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Chronic Granulomatous Disease and other conditions

United States
Vanda Pharmaceuticals

Completed

Study of the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents

Autism Spectrum Disorder | Smith-Magenis Syndrome | Non-24 Hour Sleep-Wake Disorder | Circadian Rhythm Sleep Disorders

United States
Uskudar University

Completed

The Relationship Between Phonological Awareness Skills And Home Environment Literacy in Cochlear Implant Users

Cochlear Implants | Literacy | Child Language | Phonological (Speech) Disorder

Turkey
Johns Hopkins University
National Institute on Deafness and Other Communication Disorders (NIDCD); Labyrinth...

Active, not recruiting

Multichannel Vestibular Implant Early Feasibility Study

Labyrinth Diseases | Vestibular Diseases | Sensation Disorders | Other Disorders of Vestibular Function, Bilateral | Bilateral Vestibular Deficiency (BVD) | Gentamicin Ototoxicity

United States
NYU Langone Health

Completed

Study of the Duration and Efficacy of MYDAYIS on Adult ADHD Symptoms and Executive Function Throughout the Day Into the Early Evening (MYDAYIS)

Attention Deficit-Hyperactivity

United States
Damascus University

Completed

Reducing Early Urinary Disorders After Stress Incontinence Surgery: The Role of Vaginal Wall Tension.

Stress Urinary Incontinence

Syrian Arab Republic
Biohaven Pharmaceuticals, Inc.

Available

Expanded Access Protocol of Troriluzole in Patients With Spinocerebellar Ataxia (SCA)

Spinocerebellar Ataxias | SCA
Centre Hospitalier Universitaire de la Réunion

Active, not recruiting

Impact of Teacher Training and the Introduction of Early Adjustments on the Developmental Trajectory of Children at Risk of SLLD in Pre-school. (PRISME-TSLA)

Language Disorders in Children | Learning; Developmental Disorder

Réunion
Hospital del Mar Research Institute (IMIM)

Enrolling by invitation

The Clinical Impact of the Novel Alzheimer's Blood-based Biomarkers (PLASMAR)

Neurodegenerative Diseases | Cognitive Impairment | Dementia | Alzheimer Disease | Lewy Body Disease | Frontotemporal Dementia | Vascular Dementia

Spain
General Practitioners Research Institute
University Medical Center Groningen

Active, not recruiting

Screening for Albuminuria at the First Line for Early Identification of CKD (SALINE)

Chronic Kidney Diseases | Albuminuria

Netherlands
University Hospital, Strasbourg, France

Completed

Lyme Borreliosis and Early Cutaneous Diagnostic (DIABOLYC)

Erythema Migrans

France
Beni-Suef University

Completed

Early Detection of Children With Developmental Disabilities in Assiut Governorate

Autism Spectrum Disorder | Down Syndrome | Developmental Disability | Development Delay | Motor Delay

Egypt
Second Sight Medical Products
National Institute of Neurological Disorders and Stroke (NINDS)

Active, not recruiting

Early Feasibility Study of the Orion Visual Cortical Prosthesis System

Blindness, Acquired

United States
Aziende Chimiche Riunite Angelini Francesco S.p.A
Hippocrates Research

Completed

This is a Retrospective Study on the Use of CENOBAMATE as Adjunctive Treatment in Patients Suffering From Epilepsy in Early Access Program in Germany, France and UK (CENOR)

Epilepsy | Focal Onset Seizure

United Kingdom, France, Germany
Novartis Pharmaceuticals

Completed

A Dose Range Finding Study With Open-Label Extension to Evaluate the Safety of Oral LMI070/Branaplam in Early Manifest Huntington's Disease (VIBRANT-HD)

Early Manifest Huntington Disease

Canada, Germany, France, Spain, Hungary
Groupe Hospitalier du Havre

Completed

Ultrasound Measurement of Quadriceps Shortening During Neuromuscular Electrical Stimulation in Critically Ill Patients (DETECT)

ICU Acquired Weakness | Quadriceps Muscle Atrophy

France
Balikesir University

Completed

What Are the Determinant Factors of Ceasing Anti-seizure Medication in Infants With Neonatal Seizures?

Neonatal Seizure

Turkey
Karolinska Institutet
The Swedish Research Council

Active, not recruiting

Early Life Anemia and Children's Risk of Neurodevelopmental Disorders: National and Regional Register-based Studies

Anemia | Intellectual Disability | ADHD | Neurodevelopmental Disorders | Autism

Sweden
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

S1702 Isatuximab in Treating Patients With Relapsed or Refractory Primary Amyloidosis

Nausea | Constipation | Diarrhea | Purpura | Lymphadenopathy | Gastrointestinal Hemorrhage | Hepatomegaly | Primary Systemic Amyloidosis | Amorphous, Eosinophilic, and Acellular Deposit | Early Satiety | Macroglossia | Recurrent Primary Amyloidosis | Refractory Primary Amyloidosis

United States
Ohio State University

Completed

Penetrating the Classroom Social Network for Children With Language Impairment Via Peer Mediated Intervention (PEERS)

Peer Influence

United States
Cairo University

Completed

Effect of Early Coma Arousal Therapy on Conscious Level Recovery and Cognition in Traumatic Brain Injury

Traumatic Brain Injury With Loss of Consciousness

Egypt
Alexion Pharmaceuticals, Inc.

Available

Danicopan Early Access Program

Paroxysmal Nocturnal Hemoglobinuria | PNH | Extravascular Hemolysis
University of Calgary

Active, not recruiting

Home-based Early Intensive Hemiparesis Therapy: Engaging Nurture (HEIGHTEN)

Cerebral Palsy | Perinatal Stroke

Canada
Rigshospitalet, Denmark
Frederiksberg University Hospital; Defactum, Central Denmark Region

Active, not recruiting

The Effect of Graded Activity and Pain Education (GAPE) for Patients Early After Lumbar Spinal Fusion

Low Back Pain

Denmark
ZevraDenmark

Available

Early Access Program With Arimoclomol in US Patients With NPC

Niemann-Pick Disease, Type C

United States
Vanderbilt University Medical Center
National Institutes of Health (NIH); National Institute of General Medical...

Active, not recruiting

Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study (INSIGHT-ICU)

Delirium | Critical Illness | Cognitive Impairment | Trauma | Traumatic Brain Injury | ICU | Polytrauma | Alzheimer; Early Onset

United States
Medipol University

Completed

Effect of Non-nutritive Sucking on Transition to Oral Feeding in Infants With Asphyxia

Perinatal Asphyxia | Hypoxic-Ischemic Encephalopathy | Swallowing Disorder | Feeding; Difficult, Newborn | Speech Therapy | Feeding Disorder of Infancy or Early Childhood

Turkey
Lund University
Oslo University Hospital

Completed

Protective Role of Muscle Function for Early Features of Knee Osteoarthritis After Anterior Cruciate Ligament Injury (SHIELD)

Knee Osteoarthritis | Osteoarthritis, Knee | Muscle Weakness | Anterior Cruciate Ligament Injury

Sweden, Norway
IRCCS Eugenio Medea

Enrolling by invitation

Efficacy of an Early Rhythmic Intervention in Infancy

Language Development Disorders | Infant Development | Language Development | Intervention

Italy
BioXcel Therapeutics Inc
Cognitive Research Corporation

Completed

Sub-Lingual Dexmedetomidine in Agitation Associated With Dementia (TRANQUILITY)

Dementia | Agitation,Psychomotor

United States
University of Nebraska
Robert Wood Johnson Foundation

Completed

Awakening-Breathing Coordination, Delirium Monitoring/Management & Early Mobility (ABCDE) Protocol (ABCDE)

Immobility | ICU Delirium

United States
Erasmus Medical Center

Active, not recruiting

The Effect of Early Glasses on the Development of Amblyopia (EGS)

Refractive Errors | Amblyopia

Netherlands
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore
Tanta University

Completed

MRA and ABR as Early Predictors of Bilirubin-Induced Neurologic Dysfunction in Full-term Jaundiced Neonates

Neonatal Hyperbilirubinemia

Egypt
Ain Shams University

Completed

Dexmedetomidine Versus Gabapentin Premedication on the Emergence Agitation After Rhinoplasty

Anesthesia

Egypt
Sunnybrook Health Sciences Centre
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation... and other collaborators

Completed

Sleep Disorders Managed and Assessed Rapidly in Transient Ischemic Attack (TIA) and In Early Stroke (SMARTIES)

Stroke | Sleep Apnea Syndromes | Restless Legs Syndrome | Ischemic Attack, Transient | Sleep Disorders

Canada
Ohio State University
National Heart, Lung, and Blood Institute (NHLBI); Vanderbilt University Medical... and other collaborators

Withdrawn

Determinants of Implementation Success Coordinating Ventilator, Early Ambulation and Rehabilitation Efforts (DISCOVER-ICU)

Pain | Delirium | Mechanical Ventilation Complication | Implementation Science | Sedation Complication | Intensive Care Unit Acquired Weakness

United States
University of Utah
The Hospital for Sick Children; Boston Children's Hospital

Completed

Vascular Health and Risk Factors in Children With Down Syndrome

Atherosclerosis | Down Syndrome | Cardiovascular Risk Factor

United States
University of Washington
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Early Powered Mobility for Toddlers With Cerebral Palsy Using the Permobil® Explorer Mini and a Modified Ride-On Car

Cerebral Palsy

United States

Search clinical trials for: Early Manifest

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mauritius

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations