Search clinical trials for: LPA1 antagonist

Total 33630 results

Western Michigan University School of Medicine
Bronson Methodist Hospital

Not yet recruiting

Haloperidol for Pain Control in Patients With Acute Musculoskeletal Back Pain in the Emergency Department

Back Pain | Chronic Pain
Chulalongkorn University

Not yet recruiting

"Quick-starting" of a New Combined Hormonal Contraceptive Pills, 15 mg Estetrol/3 mg Drospirenone VS 20 mcg Ethinylestradiol/75 mcg Gestodene Focusing on Ovulation Inhibition

Ultrasound Finding: Ovulation Inhibition, Ovarian Activities | Cervical Mucus | Serum Hormonal Profile
National Cancer Institute (NCI)

Not yet recruiting

Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer

Recurrent Ovarian High Grade Serous Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Fallopian Tube Undifferentiated Carcinoma | Recurrent Ovarian Clear Cell Adenocarcinoma | Recurrent Ovarian Undifferentiated Carcinoma and other conditions
Preeyaporn Jirakittidul

Not yet recruiting

The Effect of Dimenhydrinate on Postoperative Nausea and Vomiting After Abdominal Hysterectomy: Randomized-controlled Trial

Healthy Women | Gynecologic Neoplasm
Leiden University Medical Center
Karolinska Institutet; Children's Investment Fund Foundation; Women on Waves

Not yet recruiting

Efficacy, Safety, and Acceptability of Mifepristone 50 mg Once-weekly as a Contraceptive (WOMEN)

Female Contraception

Netherlands
Memorial Sloan Kettering Cancer Center
Verastem, Inc.

Recruiting

A Study of Avutometinib, Defactinib, and Letrozole in People With Low-Grade Serous Ovarian Cancer (CHAMELEON)

Low-Grade Serous Ovarian Cancer

United States
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

Immunosensitized Radiotherapy Combined With Evoximab (AK112) and Chemotherapy Neoadjuvant Therapy for Stage II-III Non-small Cell Lung Cancer

Stereotactic Radiotherapy; Evoximab (AK112); New Adjuvant Therapy for Non-small Cell Lung Cancer
Xiaojun Chen

Recruiting

GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Atypical Hyperplasia Patients

Obesity | Atypical Endometrial Hyperplasia | Progesterone Resistance

China
Beni-Suef University

Recruiting

Efficacy of Voriconazole Loaded Spanlastics Gel Versus Clotriamazole Cream on Treating Vulvovaginal Candidasis

Treatment of Vagnial Cabdudasis

Egypt
Affiliated Hospital of Jiaxing University

Recruiting

Comparison of Bupivacaine Liposomal vs Bupivacaine Combined With Dexamethasone for Postoperative Pain in VATS

Thoracic Surgery

China
Qian Qin
Janssen, LP; UT Southwestern Comprehensive Cancer Center

Not yet recruiting

Niraparib, Abiraterone Acetate and Prednisone for mHSPC With Deleterious Homologous Recombination Repair Alterations (HARMONY)

BRCA1 Gene Mutation | BRCA2 Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | CHEK2 Gene Mutation | FANCA Gene Mutation | RAD51B Gene Mutation | RAD54L Gene Mutation | Metastatic Hormone-sensitive Prostate Cancer (mHSPC) | Deleterious HRR Gene Mutation
St. Jude Children's Research Hospital
AbbVie

Not yet recruiting

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

T-cell Lymphoma | T-cell Acute Lymphoblastic Leukemia | Mixed Phenotype Acute Leukemia

United States
Robert Bok, MD, PhD
National Cancer Institute (NCI)

Not yet recruiting

Magnetic Resonance (MR) Imaging With Hyperpolarized 13C-Pyruvate +/- 13C,15N-Urea in Patients With Prostate Cancer

Prostate Cancer

United States
University of Miami

Recruiting

PSMA-Directed Para-Aortic Radiation Therapy for Oligorecurrent Prostate Cancer (OCEAN)

Prostate Cancer | Prostate Adenocarcinoma | Hormone Sensitive Prostate Cancer

United States
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1, Open-label Study Evaluating the Pharmacokinetics and Drug-drug Interaction of VX-993 in Healthy Adults

Pain

United Kingdom
Incyte Corporation

Not yet recruiting

A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease

Chronic Graft-versus-host-disease
Hospital Universiti Sains Malaysia

Not yet recruiting

Different Doses of Intravenous Administered Dexamethasone Effecting Brachial Plexus Supraclavicular Block

End Stage Renal Failure
Peking Union Medical College Hospital
Peking University; Shanghai Huilun Pharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety of Sivelestat Sodium and Dexamethasone in the Treatment of ARDS (STAR)

Acute Respiratory Distress Syndrome

China
Assiut University

Not yet recruiting

Intravenous Labetalol vs Phentolamine for the Management of Severe Preeclampsia.

Severe Pre-eclampsia
Tolmar Inc.
ICON plc

Recruiting

A Phase 4 Study to Evaluate Adrenal Function in Hypogonadal Men Treated With JATENZO® for 12 Months

Hypogonadism

United States
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Elderly/Unfit Ph- B-ALL

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Study of HRS-4642 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation

Advanced KRAS G12D Mutant Solid Tumors

China
Murdoch Childrens Research Institute

Not yet recruiting

A Study Investigating the Change in Metabolism Phenotype in Paediatric, Adolescent & Young Adults With Hodgkin or Non-Hodgkin Lymphoma. (PEGASUS)

Hodgkin Lymphoma | Non Hodgkin Lymphoma

Australia
Prisma Health-Upstate
National Institute on Drug Abuse (NIDA); Clemson University

Recruiting

Development, Refinement, and Validation of a Peer Support Specialist Checklist for Individuals With Opioid Use Disorder / STAMPS: South Carolina Buprenorphine Treatment Initiation, Adherence, and Retention Utilizing Mobile Health Units and Peer Support Specialists

Opioid Use Disorder

United States
Ivan de Kouchkovsky, MD

Not yet recruiting

Hyperpolarized (HP) 13C Pyruvate Magnetic Resonance Imaging (MRI) for Response Monitoring to Neoadjuvant Abiraterone

Prostate Cancer | High Risk Prostate Carcinoma

United States
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Recruiting

The Clinical Efficacy and Safety of Finerenone in the Treatment of Primary Aldosteronism

Primary Aldosteronism | Mineralocorticoid Receptor Antagonist | Finerenone

China
MedSIR
Stemline Therapeutics, Inc.

Not yet recruiting

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i. (ADELA)

Advanced Breast Cancer | ER-positive Breast Cancer | HER2-negative Breast Cancer | ESR1 Gene Mutation
Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study Comparing BL-B01D1 With Platinum Based Chemotherapy in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Bayesian Basket Trial (PALETTE)

Sepsis
BioMarin Pharmaceutical

Not yet recruiting

A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature

Idiopathic Short Stature
Montefiore Medical Center

Not yet recruiting

Antiemetic Fosaprepitant To Remedy Nausea and Vomiting (AFTR NV RCT)

Nausea | Vomiting | Nausea and Vomiting

United States
Wayne State University

Not yet recruiting

Warrior CARE: Cannabis Behavioral Health (CBH)

Suicide | Post Traumatic Stress Disorder | Cannabis Use | Veterans | Marijuana

United States
AstraZeneca

Not yet recruiting

Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer (EvoPAR-BR01)

Advanced Breast Cancer

Canada
Northwell Health

Recruiting

Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries

Pain, Postoperative | Postoperative Pain, Acute

United States
Isfahan University of Medical Sciences

Recruiting

Effectiveness of Intrauterine Growth Hormone Administration as an add-on Therapy to Conventional Hormone Therapy Compared to Placebo in Patients With Thin Endometrium Undergoing Frozen Thawed Embryo Transfer

Infertility | Thin Endometrium | Infertility Female

Iran, Islamic Republic of
Modern Biosciences Ltd

Recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
Johns Hopkins University
National Institutes of Health (NIH)

Not yet recruiting

Behavioral Pharmacology of Orally Administered THC and D-limonene

THC | Subjective Drug Effects | D-limonene

United States
Xiaojun Chen

Recruiting

GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Cancer Patients

Obesity | Atypical Endometrial Hyperplasia | Endometrial Neoplasms | Progesterone Resistance

China
Mayo Clinic

Recruiting

Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, DIVINE Trial (DIVINE)

Recurrent Prostate Cancer | Castration-resistant Prostate Cancer | Stage IVB Prostate Cancer AJCC v8 | Recurrent Castration-Sensitive Prostate Carcinoma

United States
Shanghai JMT-Bio Inc.

Not yet recruiting

JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Exon 20ins Mutations

Local Advanced or Metastatic NSCLC
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Rapid Outpatient Low-dose Initiation of Buprenorphine for OUD With Fentanyl Use (ROLDI)

Opioid Use Disorder
Novartis Pharmaceuticals

Not yet recruiting

NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.

Metastatic Neuroendocrine Prostate Cancer
University of Wisconsin, Madison

Not yet recruiting

Ketamine-assisted Psychotherapy for Adolescent PTSD (KAP)

Posttraumatic Stress Disorder

United States
Post Graduate Institute of Medical Education and...

Not yet recruiting

A RCT to Compare the Effectiveness of Nebulized Anticholinergics for Cough Suppression During Flexible Bronchoscopy (NAFCOF)

Subjects Undergoing Flexible Bronchoscopy

India
Mỹ Đức Hospital

Recruiting

PPOS vs GnRH Antagonist in Ovarian Stimulation (ProGanOS Study) (ProGanOS)

Progestins Primed Ovarian Stimulation

Vietnam
National Medical Research Center for Cardiology...

Recruiting

Study of Microvascular Dysfunction, CFR and Cardioprotective Effect of Early Administration of Esmolol in MI (ESMO-VASCMI)

Myocardial Infarction | Coronary Stenosis | Coronary Microvascular Dysfunction

Russian Federation
Beijing Tongren Hospital

Recruiting

Linperlisib Combined With Camrelizumab and Pegaspargase in Advanced or Relapsed/Refractory NK/T-cell Lymphoma

T-lymphoblastic Lymphoma | Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type

China
Yale University
Johns Hopkins University; University of Colorado, Denver; Northwestern University and other collaborators

Recruiting

Pre-IVF Treatment With a GnRH Antagonist in Women With endometriosis_temp (PREGnant)

Infertility | Endometriosis

United States
Ali Aminian

Not yet recruiting

Fibrosis Lessens After Metabolic Surgery (FLAMES)

Obesity | Liver Fibrosis | Non-Alcoholic Fatty Liver Disease | Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) | Metabolic Dysfunction-Associated Steatohepatitis (MASH)

United States, Sweden, Ireland, Finland, United Kingdom, Spain, Switzerland, Brazil, Canada, Italy, Kuwait, India, Mexico
The University of Texas Health Science Center,...

Recruiting

Study of Injectable Naltrexone and Oral Bupropion Among Cigarette Smokers With Schizophrenia

Smoking Cessation

United States

Search clinical trials for: LPA1 antagonist

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