Search clinical trials for: Light Chain Amyloidosis

Total 4226 results

National Cancer Institute (NCI)

Completed

4'-Iodo-4'-Deoxydoxorubicin in Treating Patients With Primary Systemic Amyloidosis

Multiple Myeloma and Plasma Cell Neoplasm

United States, Italy
University of Tennessee
Food and Drug Administration (FDA)

Completed

Radioimmunoimaging of AL Amyloidosis

AL Amyloidosis

United States
Millennium Pharmaceuticals, Inc.
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

Open-Label Phase 1/2 Study of VELCADE for Injection in Patients With Light-chain (AL)-Amyloidosis

Amyloidosis

United States
IRCCS Policlinico S. Matteo
Celgene Corporation

Completed

Cyclophosphamide, Lenalidomide and Dexamethasone (CLD) for Previously Treated Patients With AL Amyloidosis

Amyloidosis

Italy
Nantes University Hospital

Completed

Lenalidomide in Combination With Melphalan and Dexamethasone in Newly-diagnosed Light-chain (AL)-Amyloidosis

Amyloidosis

France
Mayo Clinic

Completed

Efficacy of CC-5013 (Revlimid or Lenalidomide) in Patients With Primary Systemic Amyloidosis

Amyloidosis

United States
Stanford University

Completed

Autologous Stem Cell Rescue for Primary Amyloidosis

Amyloidosis | Blood and Marrow Transplant (BMT)

United States
Herbert Irving Comprehensive Cancer Center

Completed

Study of High-Dose Melphalan and Autologous Stem Cell Transplantation in Patients With Primary Light Chain Amyloidosis

Amyloidosis

United States
University Hospital, Limoges
Ministry of Health, France

Completed

Intensive Versus Conventional Treatment in Patients With Primary Amyloidosis

Primary Systemic Amyloidosis (AL)

France
National Cancer Institute (NCI)

Not yet recruiting

Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer

Recurrent Ovarian High Grade Serous Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Fallopian Tube Undifferentiated Carcinoma | Recurrent Ovarian Clear Cell Adenocarcinoma | Recurrent Ovarian Undifferentiated Carcinoma and other conditions
Monash University
University of Melbourne; Wake Forest University; Invitae Corporation; Eastern Health and other collaborators

Recruiting

Neurofilament Light Chain And Voice Acoustic Analyses In Dementia Diagnosis (NAVAIDD)

Neurodegenerative Diseases | Dementia

Australia
National Cancer Institute (NCI)

Not yet recruiting

Anti-Lag-3 (Relatlinib) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Recurrent Glioblastoma
Heinrich-Heine University, Duesseldorf

Recruiting

The VANGAS-Trial. The Value of Neurofilament Light Chain and Glial Fibrillary Acid Protein in the Blood of Patients With Asymptomatic Carotid Artery Stenosis (VANGAS)

Carotid Artery Plaque | Carotid Artery Diseases | Carotid Artery Stenosis Asymptomatic | Carotid Artery Stenosis

Germany
Charite University, Berlin, Germany
Boris Canessa ALS Stiftung

Recruiting

Neurofilament Light Chain in Amyotrophic Lateral Sclerosis (NfL-ALS)

Motor Neuron Disease | Amyotrophic Lateral Sclerosis

Germany, Austria
Technische Universität Dresden

Recruiting

Biological and Cognitive Marker of Neurodegeneration in Obstructive Sleep Apnea Patients

Sleep Apnea, Obstructive

Germany
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Not yet recruiting

Retifanlimab With Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma

Recurrent Glioblastoma | Recurrent WHO Grade 4 Glioma

United States
University Hospital, Basel, Switzerland

Recruiting

MultiSCRIPT-Cycle 1: Personalized Medicine in Multiple Sclerosis - Pragmatic Platform Trial Embedded Within the SMSC

Multiple Sclerosis, Relapsing-Remitting

Switzerland
Assiut University

Not yet recruiting

NF-L Chain Measurement in Acute Ischemic Stroke

Acute Stroke
University Hospital Hradec Kralove

Recruiting

Role of Brain Specific Biomarkers in Hydrocephalus

Brain Damage | Hydrocephalus, Normal Pressure | Biochemical Lesions Head Region

Czechia
Assiut University

Not yet recruiting

Neurofilament Light Chain as a Potential Marker in Behcet's Disease

Behçet
National Cancer Institute (NCI)

Recruiting

Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer

Recurrent Nasopharyngeal Carcinoma | Stage IV Nasopharyngeal Carcinoma AJCC v8 | Metastatic Nasopharyngeal Carcinoma

United States, Hong Kong
National Cancer Institute (NCI)

Recruiting

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder for Bladder Cancer Treatment, MODERN Study

Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage IV Bladder Urothelial Carcinoma AJCC v7 | Stage II Bladder Urothelial Carcinoma AJCC v6 and v7 | Muscle Invasive Bladder Urothelial Carcinoma

United States
Brugmann University Hospital

Recruiting

Multimodal Exploration of Patients With Multiple Sclerosis for an Early Detection of Subtle Progression

Multiple Sclerosis

Belgium
University Hospital, Basel, Switzerland
University of Zurich

Recruiting

Novel Targetable BIOmarkers in ANorexia NervosA (BIOANNA)

Anorexia Nervosa | Anorexia Nervosa Restricting Type

Switzerland
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Metastatic Malignant Neoplasm in the Liver | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Unresectable Colorectal Carcinoma

United States
Ambulanzpartner Soziotechnologie APST GmbH
Charite University, Berlin, Germany

Recruiting

Clinical Characteristics, Natural History, Health Care Measures, and Genetic Screening in Patients With ALS (ID-ALS)

Motor Neuron Disease, Amyotrophic Lateral Sclerosis

Germany
Ambulanzpartner Soziotechnologie APST GmbH
Charite University, Berlin, Germany

Recruiting

Registry Study of Assistive Devices, Medicines and Healthcare Measures in ALS, SMA and Other Neurological Diseases.

Amyotrophic Lateral Sclerosis

Germany
I.R.C.C.S. Fondazione Santa Lucia

Recruiting

Effect of Transcranial Direct Current Stimulation (tDCS) on Post-stroke Patients on Neuromotor Recovery

Stroke

Italy
Odense University Hospital
Aarhus University Hospital; University of Southern Denmark; Sygehus Lillebaelt

Recruiting

Prediction of Getting Peripheral Neuropathy in Patients Treated With Bortezomib? (NFL-BIOPAIN)

Chemotherapy-induced Peripheral Neuropathy

Denmark
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colon Cancer AJCC v8 | Stage IV Colorectal Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8 | Metastatic Microsatellite Stable Colorectal Carcinoma

United States
Ain Shams University

Not yet recruiting

Effect of Ambroxol in Diabetic Peripheral Neuropathy

Diabetic Neuropathy Peripheral

Egypt
University of Oxford
Oxford University Hospitals NHS Trust

Recruiting

Biomarkers Associated With Postoperative Cognitive Dysfunction

Delirium | Cognitive Impairment | Postoperative Cognitive Dysfunction | Cognitive Decline

United Kingdom
Assiut University

Not yet recruiting

Neurofilament Light Chain ,Chitinase-3 Like-1 Proteins and Plasmacytoid Dendritic Cells in Multiple Sclerosis

Multiple Sclerosis
Queen Mary University of London
Biogen; Barts & The London NHS Trust; Moorfields Eye Hospital NHS Foundation... and other collaborators

Recruiting

Natalizumab for the Treatment of People With Inflammatory Demyelination Suggestive of Multiple Sclerosis, or Definite Multiple Sclerosis, at First Presentation (AttackMS) (AttackMS)

Multiple Sclerosis | Clinically Isolated Syndrome of Demyelination

United Kingdom
Light Chain Bioscience - Novimmune SA

Recruiting

A Study of NI-1801 in Patients With Mesothelin Expressing Solid Cancers

Triple Negative Breast Cancer | Epithelial Ovarian Cancer | Non-squamous Non-small-cell Lung Cancer

Italy, France
University Hospital Hradec Kralove

Recruiting

The Role of Neurofilament Light (NfL) in Patients With Hydrocephalus

Brain Damage | Hydrocephalus | General Anesthetics Toxicity

Czechia
University Hospital, Basel, Switzerland

Recruiting

Association of Intraoperative Blood Pressure Excursions Below Cerebral Autoregulatory Boundaries With Organ Injury Following Major Noncardiac Surgery (AR-NONCARDIAC)

Intraoperative Arterial Hypotension

Switzerland
Roswell Park Cancer Institute
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; Celldex Therapeutics

Recruiting

Pembrolizumab Combined With Bevacizumab With or Without Agonist Anti-CD40 CDX-1140 for the Treatment of Patients With Recurrent Ovarian Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Endometrial Serous Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Platinum-Sensitive Ovarian Carcinoma | Recurrent Fallopian... and other conditions

United States
First Affiliated Hospital of Fujian Medical University
Peking Union Medical College Hospital; Fujian Medical University Union Hospital

Recruiting

Antisense Oligonucleotide for Spinal Muscular Atrophy

Spinal Muscular Atrophy

China
Novartis Pharmaceuticals

Recruiting

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS) (REMODEL-2)

Relapsing Multiple Sclerosis

United States, Canada, China, Spain, Italy, France, Slovenia, Japan, Turkey, Argentina, Estonia, Greece, Mexico, Poland, Sweden, Croatia, South Africa, Brazil, Slovakia, Bulgaria, Romania, India, Portugal, United Kingdom, Puerto Rico
Novartis Pharmaceuticals

Recruiting

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS) (REMODEL-1)

Relapsing Multiple Sclerosis

China, Spain, Switzerland, Taiwan, United States, Italy, Austria, Belgium, Saudi Arabia, United Arab Emirates, Latvia, Poland, Argentina, India, Croatia, Bulgaria, Malaysia, Slovakia, Israel, Lebanon, Guatemala, Netherlands, Colombia, Chil... and more
Francis Corazza

Recruiting

Prognostic Value of Cerebrospinal Fluid Immunoglobulin Free Light Chains in Patients With Multiple Sclerosis

Multiple Sclerosis

Belgium
National Cancer Institute (NCI)

Recruiting

Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage IV Hypopharyngeal... and other conditions

United States
M.D. Anderson Cancer Center

Recruiting

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

Chondrosarcoma | Advanced Malignant Solid Neoplasm | Stage III Uterine Corpus Cancer AJCC v8 | Stage IV Uterine Corpus Cancer AJCC v8 | Stage IVA Uterine Corpus Cancer AJCC v8 | Stage IVB Uterine Corpus Cancer AJCC v8 | Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIB Cutaneous... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma

Peritoneal Malignant Mesothelioma

United States
National Cancer Institute (NCI)

Recruiting

Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer

Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Papillary Renal Cell Carcinoma | Hereditary Leiomyomatosis and Renal Cell Carcinoma | Sporadic Papillary Renal Cell Carcinoma

United States
Hôpital le Vinatier

Recruiting

Neurofilament Light Chains and Cognitive Impairment in Chronic Psychiatric Disease (Nfl_COG)

Schizophrenia | Alzheimer Disease | Bipolar Disorder | FTD

France
Second Affiliated Hospital, School of Medicine,...

Recruiting

Clinical Study for AL-CM

Immunoglobulin Light Amyloidosis Cardiomyopathy

China
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Recruiting

APL-2 and Pembrolizumab Versus APL-2, Pembrolizumab and Bevacizumab Versus Bevacizumab Alone for the Treatment of Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer and Malignant Effusion

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Fallopian Tube Clear Cell Adenocarcinoma | Fallopian Tube Endometrioid Adenocarcinoma | Fallopian Tube Serous Adenocarcinoma and other conditions

United States
University of Michigan

Recruiting

The Biomarkers in the Hyperbaric Oxygen Brain Injury Treatment Trial (BioHOBIT)

Traumatic Brain Injury

United States, Canada

Search clinical trials for: Light Chain Amyloidosis

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