Search clinical trials for: Severe

Total 8596 results

Eli Lilly and Company

Recruiting

Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)

Type 2 Diabetes

United States, Argentina, United Kingdom, Puerto Rico
Shanghai Ming Ju Biotechnology Co., Ltd.

Not yet recruiting

Relma-cel for Moderate to Severe Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio

Not yet recruiting

Clinical-functional Effects of Bariatric Surgery on the Musculoskeletal System in Relation to Bone Turnover.

Bariatric Surgery Candidate
Merck Sharp & Dohme LLC

Not yet recruiting

A Study of MK-8527 in Participants With Moderate and Severe Renal Impairment (MK-8527-008)

Renal Impairment
Sana Biotechnology

Recruiting

Study Evaluating SC291 in Subjects With Severe r/r B-cell Mediated Autoimmune Diseases (GLEAM) (GLEAM)

Systemic Lupus Erythematosus | Microscopic Polyangiitis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Lupus Erythematosus | SLE (Systemic Lupus) | Granulomatous Polyangiitis

United States
Johns Hopkins University
University of Maryland, Baltimore; McMaster University; Orthopaedic Trauma Association and other collaborators

Not yet recruiting

Accelerated Flap Coverage in Severe Lower Extremity Trauma (FLAP ATTACK)

Open Tibia Fracture | Extremity Fracture Lower | Open Dislocation of Ankle | Extremity Injuries Lower

United States, Australia, Spain
Unity Health Toronto

Recruiting

Susceptibility for Entrainment: Role of Ventilator Settings on the Occurrence of Reverse Triggering and Its Physiological Consequences - the SEVeRe Study (SEVERE)

Respiration, Artificial | Reverse Triggering

Canada
Gilead Sciences

Recruiting

Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis (SWIFT)

Ulcerative Colitis

United States
Jiani Wu

Not yet recruiting

TaVNS Improves the Symptoms of Patients With Moderate to Severe CP/CPPS

Chronic Prostatitis

China
Aristotle University Of Thessaloniki
University Hospital of Crete; University Hospital of Patras; Pulmonary Clinic... and other collaborators

Recruiting

BenRalizumab Effect on Airway Remodeling in Severe asTHma (BREATH)

Airway Remodeling | Asthma; Eosinophilic

Greece
UNICEF - Venezuela

Recruiting

Treatment of Acute Malnutrition in Outpatient Care Services in Venezuela: a Prospective Cohort Research

Wasting | Acute Malnutrition in Childhood | Child Malnutrition

Venezuela
Capital Medical University

Recruiting

Diagnosis and Treatment Strategy Optimization of Severe Pneumonia Based on Multi-omics Data Integration

Severe Community-acquired Pneumonia

China
Massachusetts General Hospital

Not yet recruiting

CPAP in Patients With Severe Obesity After Anesthesia

Anesthesia Morbidity | Obesity, Abdominal | Ventilator Lung | Apnea, Obstructive Sleep | Atelectases, Postoperative Pulmonary
Centre Hospitalier Universitaire de Nīmes

Not yet recruiting

Experience of Parents/Carers of Children With Severe Motor Disabilities Suffering From Spinal Pain? (Vé-Quo-Pa-H-R)

Low Back Pain
Gerbera Therapeutics, Inc.

Not yet recruiting

A Study to Assess the Efficacy, Safety, and Tolerability of Oral NORA520 in Adults With Severe Postpartum Depression (NuMom)

Postpartum Depression | Depression, Postpartum | Postnatal Depression | Post-partum Depression | Post-Natal Depression

United States
Second Affiliated Hospital of Nanchang University
Changhai Hospital

Recruiting

Early Lumbar Drainage Combined With Intrathecal Urokinase Injection for Treatment of Severe Aneurysmal SAH (LD-ITUK)

Aneurysmal Subarachnoid Hemorrhage

China
University of Arizona
United States Department of Defense

Not yet recruiting

Safety and Efficacy of Angiotensin (1-7) in Persons With Moderate to Severe Traumatic Brain Injury (ANGel T)

Traumatic Brain Injury
AstraZeneca

Recruiting

PROPE Severe Asthma Study in Egypt

Severe Asthma

Egypt
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Improving Diagnosis and Prediction of Outcome in Patients With Severe Disorders of Consciousness (IMPROVE-DOC)

Stroke | Encephalitis | Traumatic Brain Injury | Meningitis | Intracranial Hemorrhages | Subarachnoid Hemorrhage

Netherlands
Innovaderm Research Inc.

Not yet recruiting

Efficacy, Safety, and Tolerability of Abrocitinib in Subjects With Moderate to Severe Chronic Hand Eczema Refractory to Corticosteroid Therapy

Chronic Hand Eczema

Canada
University Hospital, Rouen

Not yet recruiting

Nebulized Fentanyl in Healthy Volunteers (AEROfen)

Emergencies | Analgesia

France
Peking University People's Hospital

Not yet recruiting

Sirolimus+Abatacept+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to Calcineurin Inhibitors

Myelodysplastic Syndromes | Acute Leukemia | Severe Aplastic Anemia
Eli Lilly and Company

Recruiting

A Study of Lebrikizumab (LY3650150) With/Without Topical Corticosteroid Treatment in Participants With Moderate-to-Severe Atopic Dermatitis

Atopic Dermatitis

China, Korea, Republic of
Alireza Shamshirsaz

Not yet recruiting

Fetal Endotracheal Occlusion (FETO) in Fetuses With Severe Congenital Diaphragmatic Hernia

Congenital Diaphragmatic Hernia

United States
InventisBio Co., Ltd

Recruiting

Evaluate the Efficacy and Safety of D-2570 in Participants With Moderate-to-Severe Plaque Psoriasis

Plaque Psoriasis

China
China National Center for Cardiovascular Diseases

Recruiting

Cardiac Denervation Ablation Strategy for Severe Sinus Bradycardia

Sinus Bradycardia

China
Lynk Pharmaceuticals Co., Ltd

Recruiting

A Phase 3 Study of LNK01001 Capsule in Subjects With Moderate to Severe Atopic Dermatitis.

Atopic Dermatitis

China
Baylor College of Medicine
University of Texas

Recruiting

Telehealth Behavioral Activation for Teens

Depression | Depression Moderate | Depression Severe | Suicide and Self-harm | Depression in Adolescence | Depression Mild

United States
EMS

Not yet recruiting

Efficacy and Safety of DEP114 in the Treatment of Moderate to Severe Persistent Allergic Rhinitis in Children. (SIERRA)

Allergic Rhinitis
Zhejiang University
Beijing YouAn Hospital; Beijing Ditan Hospital; Huashan Hospital; Qilu Hospital...

Not yet recruiting

A Multicenter Prospective Clinical Cohort Study on the Pathogen Spectrum of Severe Hepatitis (Liver Failure) Complicated With Infection

Liver Failure
Nantes University Hospital

Not yet recruiting

Dexamethasone for Treating Severe Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype (HAP-DEX)

Hospital Acquired Pneumonia

France
Kodiak Sciences Inc

Recruiting

A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy (NPDR) (GLOW2)

Non-proliferative Diabetic Retinopathy

United States, Puerto Rico
Assiut University

Not yet recruiting

Value Of ACE Index (Albumin, CRP And Endoscopy) In Predicting Intra Venous Steroid Response In Acute Severe Ulcerative Colitis In Assiut University Hospitals

Early Detection of Complication of Ulcerative Colitis
Sohag University

Not yet recruiting

Comparative Study of Intravenous Labetalol Versus Intravenous Nitroglycerin Versus Sublingual Nifedipine

Severe Preeclampsia
Erasmus Medical Center

Not yet recruiting

Learning by Heart: The Effectiveness of an EF Training Program for Pre-schoolers With a Severe CHD (LbH)

Congenital Heart Disease | Executive Dysfunction | Attention Disorder

Netherlands
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Severe Erythema Multiforme - CORTICO (SEMCORTICO)

Erythema Multiforme
Advanced Bionics AG

Not yet recruiting

Hearing and Structure Preservation Via ECochG (PRESERVE)

Hearing Loss, Sensorineural | Severe-to-profound Hearing Loss

Belgium, United Kingdom, France, Germany, Italy, Poland
Association Clinique Thérapeutique Infantile du...
Centre National de Référence des staphylocoques; GFRUP (Groupe Francophone... and other collaborators

Recruiting

CommunautAry Pediatric bacteRial Infection in Intensive CarE Unit (CAPRICE)

Severe Infection | Hospitalized Children | Invasive Bacterial Infection

France
Janssen Research & Development, LLC

Recruiting

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis (QUASAR Jr)

Colitis, Ulcerative

Belgium, United States, China, Denmark, Spain, Japan, Italy, Turkey, Poland, France, Portugal
AstraZeneca

Recruiting

A Retrospective Chart Review to Investigate Clinical Remission in Patients With Severe Asthma Treated With Biologics in the United Kingdom National Health Service (REMISSION UK)

Asthma

United Kingdom
Tasly Pharmaceutical Group Co., Ltd

Recruiting

A Study of the Effectiveness and Safety of JS1-1-01 in Patients With Moderate to Severe Depression

Depression

China
Bristol-Myers Squibb

Not yet recruiting

Real-World Safety and Effectiveness of Sotyktu (Deucravacitinib) in Patients With Moderate-to-Severe Plaque Psoriasis in Korea

Moderate-to-severe Plaque Psoriasis

Korea, Republic of
Alimentiv Inc.
Takeda

Not yet recruiting

VECTORS - A Study to Evaluate Transmural Healing as a Treatment Target in Crohn's Disease (VECTORS)

Crohn Disease | Moderately to Severely Active Crohn's Disease | Disease Crohn
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Mepolizumab in the Treatment of Patients With Severe Uncontrolled CRSwNP: a Multicentric Real Life Observational Study (MEPOREAL)

Chronic Rhinosinusitis With Nasal Polyps

Italy
Tianjin Medical University Cancer Institute and...

Not yet recruiting

Stereotactic Body Radiation Therapy Followed by NALIRIFOX vs NALIRIFOX for Borderline Resectable Pancreatic Cancer

Pancreatic Cancer
Alexis FERRE

Recruiting

Patients With Severe Acute Exacerbation of COPD Ans Admitted in ICU Register. (COPDregister)

COPD Exacerbation

France
Ferran Morell

Not yet recruiting

Severe Prospective Observational COPD Catalonia (SPOCCAT)

Severe Chronic Obstructive Pulmonary Disease
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Trial of HHPG-19K Injection and Auto-HHPG-19K Injection in Prevention of Chemotherapy-related Moderate to Severe Neutropenia of Patients With Nonmyeloid Malignancies

Patients With Nonmyeloid Malignancies Receiving Antineoplastic Therapy Based on Chemotherapy Regimens at Moderate to High Febrile Neutropenia (FN) Risk

China
Century Therapeutics, Inc.

Not yet recruiting

A Study of CNTY-101 in Participants With Moderate to Severe Systemic Lupus Erythematosus (SLE) (CALiPSO-1)

Systemic Lupus Erythematosus
Institute of Hematology & Blood Diseases Hospital...

Recruiting

Rituximab for Serious Aplastic Anemia With Platelet Transfusion Refractoriness

Platelet Transfusion Refractoriness | Severe Aplastic Anemia

China

Search clinical trials for: Severe

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