Search clinical trials for: single port

Total 31295 results

Pontificia Universidade Católica do Rio Grande...
ITI International Team for Implantology, Switzerland

Completed

Short Implants Supporting Single Crowns in the Posterior Region

Quality of Life | Dental Implants | Dental Prosthesis

Brazil
Universidad El Bosque, Bogotá
King's College London; University of Leeds; University of Sheffield

Completed

Pandemic-adapted Caries Care Multicentre Single-group Interventional Study

Dental Caries in Children

Mexico, United Kingdom, Brazil, Peru, United States, Portugal, Argentina, Colombia, Dominican Republic, France, Netherlands, Russian Federation, Uruguay
Bayer

Terminated

Study of Copanlisib in Combination With Standard Immunochemotherapy in Relapsed Indolent Non-Hodgkin's Lymphoma (iNHL) (CHRONOS-4)

Lymphoma, Non-Hodgkin

United States, Hungary, China, Belgium, Korea, Republic of, France, Australia, Russian Federation, Taiwan, Denmark, Japan, United Kingdom, Spain, South Africa, Turkey, Romania, Singapore, Israel, Ireland, Canada, Poland, Greece, Cze... and more
Memorial Sloan Kettering Cancer Center
University of Pisa; University of California, San Francisco; The Champalimaud...

Active, not recruiting

Randomized Study Comparing Two Dosing Schedules for Hypofractionated Image-Guided Radiation Therapy

Melanoma | Sarcoma | Ovarian Cancer | Bone | Soft Tissue | Lymph Nodes | CNS-Spinal CD/MEMBR, NOS

United States, Italy, Portugal
European Organisation for Research and Treatment...

Active, not recruiting

Very Early PET-response Adapted Targeted Therapy for Advanced Hodgkin Lymphoma: a Single -Arm Phase II Study (COBRA)

Advanced Hodgkin Lymphoma

Belgium, Spain, Netherlands, Denmark, Poland, Portugal, Slovakia
EDDC (Experimental Drug Development Centre), A*STAR...
PPD

Active, not recruiting

A Study to Evaluate the Safety and Tolerability of ETC-1922159 as a Single Agent and in Combination With Pembrolizumab in Advanced Solid Tumours

Solid Tumors

United States, Singapore
Hoffmann-La Roche

Completed

A Study of Atezolizumab Compared With a Single-Agent Chemotherapy in Treatment Naïve Participants With Locally Advanced or Recurrent or Metastatic Non-Small Cell Lung Cancer Who Are Deemed Unsuitable For Platinum-Doublet Chemotherapy (IPSOS)

Non-Small Cell Lung Cancer

Canada, Belgium, Brazil, China, Denmark, Portugal, Spain, United Kingdom, Argentina, Bulgaria, Colombia, Germany, India, Ireland, Italy, Luxembourg, Mexico, Poland, Romania, Slovakia, Switzerland, Vietnam, Kazakhstan, Czechia
Coopervision, Inc.
Visioncare Research Ltd.

Completed

Dual Focus Soft Contact Lens Wear Cessation Study

Myopia

Canada, Portugal, Singapore, United Kingdom
Chang Gung Memorial Hospital

Active, not recruiting

Single Port Robotic Lung Anatomical Resection

Robotic Surgical Procedure

Taiwan
Regeneron Pharmaceuticals

Active, not recruiting

CemiplimAb Survivorship Epidemiology (CASE)

Basal Cell Carcinoma | Cutaneous Squamous Cell Carcinoma

United States, Puerto Rico
Restor3D

Completed

A Single Time-Point Study to Evaluate the ConforMIS iTotal® (CR) Knee Versus Off-the-Shelf (STEPS)

Osteoarthritis

United States, Germany
Abbott Medical Devices

Active, not recruiting

HALO: A Single Arm Prospective Investigation of the SJM™ Masters HP™ 15mm Rotatable Mechanical Heart Valve

Mitral Valve Disease | Damaged Mitral Valve | Malfunctioning Mitral Heart Valve | Mitral Valve Replacement

United States
Achieve Life Sciences

Completed

Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics of a Single 3 mg Cytisinicline Dose

Renal Impairment

Spain, Portugal
Achieve Life Sciences

Completed

Study to Evaluate Effect of Food on Bioavailability of Single 3 mg Tablet and Pharmacokinetics (PK) of Multiple 3 mg Doses in Healthy Adult Smokers

Smoking Cessation

Portugal
Tesaro, Inc.

Completed

Effects of Single Agent Niraparib and Niraparib Plus Programmed Cell Death-1 (PD-1) Inhibitors in Non-Small Cell Lung Cancer Participants

Neoplasms

United States
Stanford University

Terminated

Concurrent Use Lymphoseek & Indocyanine Green in Sentinel Lymph Node Detection in Endometrial Cancer

Endometrial Cancer

United States
Penn State University
Jenny Craig, Inc.

Completed

Combined Effects of Sequential Variety and Portion Size on Meal Intake of Women

Eating Behavior

United States
Takeda

Completed

A Study of Oral Ixazomib Maintenance Therapy in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Not Treated With Stem Cell Transplantation (SCT)

Multiple Myeloma

France, Spain, United States, Taiwan, Korea, Republic of, Israel, Australia, Czechia, Hungary, Canada, Japan, Portugal, Singapore, United Kingdom, Italy, Sweden, Poland, Germany, China, Denmark, Greece, Thailand, Serbia, Turkey, Colombia, Russian Federation and more
ppharmaand GmbH
Bristol-Myers Squibb; Gynecologic Oncology Group; European Network of Gynaecological... and other collaborators

Active, not recruiting

A Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy (ATHENA)

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal | Newly Diagnosed | FIGO Stage III-IV | Partial Response | Complete Response

United States, United Kingdom, Korea, Republic of, Russian Federation, Canada, Denmark, Taiwan, New Zealand, Ireland, Japan, Spain, Australia, Israel, Italy, Greece, Sweden, Czechia, Finland, Poland, Belgium, Germany, Romania, Singa... and more
Canadian Cancer Trials Group
National Cancer Institute (NCI); ETOP IBCSG Partners Foundation; ICR-CTSU

Completed

A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer

Breast Cancer

United States, Canada, Switzerland, United Kingdom
Takeda

Active, not recruiting

A Study of Oral Ixazomib Citrate (MLN9708) Maintenance Therapy in Participants With Multiple Myeloma Following Autologous Stem Cell Transplant

Multiple Myeloma | Autologous Stem Cell Transplant

United States, Spain, Australia, Czechia, Hungary, Taiwan, Italy, Denmark, Portugal, Singapore, Israel, Canada, France, Belgium, United Kingdom, Germany, Japan, Austria, Netherlands, Korea, Republic of, Poland, Greece, Colombia, Sweden, South Africa and more
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Active, not recruiting

Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease

Metastatic Malignant Neoplasm in the Brain

United States, Canada
AstraZeneca

Completed

A Study to Investigate the Safety, Tolerability and Effects of AZD8630 in Healthy Subjects and Subjects With Asthma on Inhaled Corticosteroids and Long-acting Beta-agonists

Asthma

United States, Germany, United Kingdom
Portola Pharmaceuticals

Completed

An Open-Label, Single-Dose, Mass-Balance Study to Assess the Disposition of 14C-Labeled PRT054021 in Healthy Male Subjects

Health Volunteers
Portola Pharmaceuticals

Completed

Single Ascending Dose Study of PRT064445, a Factor Xa (fXa) Inhibitor Antidote

Healthy

United States
Hoffmann-La Roche

Terminated

A Study of Atezolizumab as Adjuvant Therapy in Participants With Renal Cell Carcinoma (RCC) at High Risk of Developing Metastasis Following Nephrectomy (IMmotion010)

Renal Cell Carcinoma

Korea, Republic of, United States, Canada, United Kingdom, Argentina, Australia, Belgium, Brazil, China, Denmark, Ireland, Spain, Japan, Netherlands, Chile, Czechia, Italy, France, Israel, Turkey, Germany, Austria, Taiwan, Serbia, Poland, Thailan... and more
Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health...

Active, not recruiting

Randomization of Single vs Multiple Arterial Grafts (ROMA)

Heart Diseases | Coronary Artery Disease

United States, Brazil, Canada, Singapore, Italy, Germany, China, Croatia, Serbia, Portugal, Austria, Czechia, Japan, Korea, Republic of, Netherlands, Poland, Spain
Eisai Inc.

Completed

A Study of Single-Agent Eribulin Mesylate as First-Line Therapy for Locally Recurrent or Metastatic Human Epidermal Growth Factor Receptor Two (HER2) Negative Breast Cancer

Locally Recurrent | Metastatic Breast Cancer ( HER2 Negative)

United States
Celgene

Completed

Safety and Efficacy of Pomalidomide, Bortezomib and Low-dose Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma (OPTIMISMM)

Multiple Myeloma

United States, Spain, United Kingdom, Italy, Israel, Portugal, Germany, Turkey, Greece, Ireland, Austria, Norway, Netherlands, Denmark, Poland, France, Russian Federation, Canada, Finland, Japan, Puerto Rico, Sweden
Salubris Biotherapeutics Inc

Withdrawn

Single-Ascending Dose Study of JK07 in Subjects With HFpEF

Heart Failure With Preserved Ejection Fraction

United States
University of Zurich
ITI Foundation

Active, not recruiting

Monolithic Zirconia Crowns for Single Implants in the Molar Region: a Multicenter Clinical Trial (MonoZrO2crown)

Implant-supported Single Crowns

Switzerland
Second Affiliated Hospital of Wenzhou Medical University

Completed

Application of Spaghetti Knotting Technology in Single-hole Laparoscopic Suturing Instructional Program on the Basis of Multidirectional Stitching Technology.

Knotting Methods | Single-port Laparoscopic Surgery

China
Astellas Pharma Global Development, Inc.
Merck Sharp & Dohme LLC

Completed

A Multiple-dose Study of ASP8374, an Immune Checkpoint Inhibitor, as a Single Agent and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

Advanced Solid Tumors

United States, Korea, Republic of, Taiwan, Portugal, Spain, United Kingdom, Italy, Canada, Japan
Chang Gung Memorial Hospital
Intuitive Surgical

Active, not recruiting

Pilot Study of Single-port Robot-assisted Nipple-sparing Mastectomy

Breast Cancer | BRCA1 Mutation | BRCA2 Mutation | Nipple-sparing Mastectomy | Prophylactic Mastectomy

Taiwan
Medical Research Council

Active, not recruiting

Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy (STAMPEDE)

Prostate Cancer

United Kingdom, Switzerland
Gate Neurosciences, Inc

Completed

Multiple Ascending Dose and Electroencephalography Trial of GATE-202 in Healthy Volunteers

Major Depressive Disorder

United States
Oxford University Hospitals NHS Trust
University Hospital Southampton NHS Foundation Trust; University Hospital Birmingham

Completed

Diagnostic Accuracy of WEARable TECHnology Single-lead ECG in Detecting Cardiac Arrhythmias (WEAR-TECH ECG)

Atrial Fibrillation | Cardiac Arrhythmia

United Kingdom
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Bayer; United States Department of Defense; Canadian...

Terminated

Aspirin in Preventing Recurrence of Cancer in Patients With HER2 Negative Stage II-III Breast Cancer After Chemotherapy, Surgery, and/or Radiation Therapy

Node Positive HER2 Negative Breast Cancer

United States, Canada, Puerto Rico, Guam
Nektar Therapeutics
Bristol-Myers Squibb

Completed

A Single-Arm Study of Bempegaldesleukin (NKTR-214) Plus Nivolumab in Cisplatin Ineligible Patients Who Have Locally Advanced or Metastatic Urothelial Cancer (PIVOT-10)

Neoplasm Metastasis | Urinary Bladder Neoplasm

United States, Spain, United Kingdom, Belgium, Canada, Australia, France, Italy, Greece, Germany, Portugal, Argentina, Israel, Russian Federation, Turkey, Mexico, Finland, Netherlands
Terumo Europe N.V.

Completed

Prospective Single Arm CAS - ROADSAVER Study (ROADSAVER)

Carotid Artery Stenosis

Belgium, Spain, Czechia, France, Serbia, Netherlands, Germany, Hungary, North Macedonia, Latvia, Poland, Portugal, Slovakia
Alessandro Pasqualotto
Hospital de Clinicas de Porto Alegre; Irmandade Santa Casa de Misericórdia... and other collaborators

Completed

Randomized Trial of Liposomal Amphotericin B for Histoplasmosis in AIDS Patients

AIDS | Histoplasmosis

Brazil
REGENXBIO Inc.

Active, not recruiting

A Long-term Follow-up Study to Evaluate the Safety and Efficacy of RGX-501

Homozygous Familial Hypercholesterolemia (HoFH)

United States, Canada, Netherlands
Millennium Pharmaceuticals, Inc.

Completed

A Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of TAK-079 Administered Subcutaneously as a Single Agent in Participants With Relapsed/Refractory (r/r) Multiple Myeloma (MM)

Multiple Myeloma | Relapsed/Refractory

United States
Hoffmann-La Roche

Completed

A Study of Atezolizumab in Combination With Bevacizumab Versus Sunitinib in Participants With Untreated Advanced Renal Cell Carcinoma (RCC) (IMmotion151)

Renal Cell Carcinoma

Korea, Republic of, United States, France, Italy, United Kingdom, Canada, Australia, Brazil, Denmark, Spain, Turkey, Japan, Czechia, Singapore, Thailand, Taiwan, Russian Federation, Germany, Bosnia and Herzegovina, Poland, Mexico
Norwegian Institute of Public Health
University of Oslo; Oslo University Hospital; Oslo Municipality

Active, not recruiting

Does the New Fall- and Fracture Prevention Initiative in Oslo Have Effect?

Hip Fractures | Fall Injury
Mayo Clinic

Completed

Performance and Accuracy of an AI Enhanced Smart Watch Single Lead ECG (PROCESS)

Healthy

United States
Universidade do Porto

Completed

Differences Between Two Type Implants in Post-extraction Alveolus

Dental Implants, Single-Tooth

Portugal
Revance Therapeutics, Inc.
Syneos Health

Completed

Single Treatment of DaxibotulinumtoxinA for Injection in Adults With Isolated Cervical Dystonia (ASPEN-1) (ASPEN-1)

Cervical Dystonia

United States, Spain, Germany, Austria, Poland, France, Canada, Czechia, United Kingdom
Editas Medicine, Inc.

Active, not recruiting

Single Ascending Dose Study in Participants With LCA10

Retinal Degeneration | Eye Diseases, Hereditary | Vision Disorders | Leber Congenital Amaurosis 10 | Inherited Retinal Dystrophies | Retinal Disease | Eye Disorders Congenital

United States
Asan Medical Center

Completed

Feasibility Study of Laparoendoscopic Single Site Surgical Staging for Endometrial Cancer (LESS-E)

Endometrial Cancer

Korea, Republic of

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