Clinical Trials Sponsored by HumanOptics AG

Total 2350 results

Canadian Cancer Trials Group
Roche Pharma AG; Janssen, LP; Karyopharm Therapeutics Inc

Recruiting

Novel Combination Therapy in the Treatment of Relapsed and Refractory Aggressive B-Cell Lymphoma

Lymphoma

Canada
Centre Hospitalier Universitaire de Besancon
Roche Pharma AG; National Cancer Institute, France

Active, not recruiting

Combination of UCPVax Vaccine and Atezolizumab for the Treatment of Human Papillomavirus Positive Cancers (VolATIL) (VolATIL)

Cervical Cancer | Squamous Cell Carcinoma of the Head and Neck | Anal Canal Cancer

France
Alpinia Laudanum GmbH
BioTeSys GmbH

Completed

Evaluation of Acacia Gum on Microbiome and Bowel Function in Participants With Chronic Constipation

Constipation

Germany
Sonova AG
Gilles Courtois; Vincent Grimaldi; Eleftheria Georganti; Peter Derleth; David Sooprayen

Completed

Subjective Evaluation of a Sound Processing Method for Hearing Aids on Auditory Distance Perception (EXTEND)

Hearing Disorders | Hearing Loss, Sensorineural

Switzerland
Leonardo Marchini
Ivoclar Vivadent AG; Delta Dental of Iowa

Completed

Oral Hygiene Intervention Pilot Study

Gingivitis | Dental Caries

United States
Kyungpook National University Hospital
Roche Pharma AG; Fresenius Medical Care North America

Completed

Impact of Dialysis Modality on Hepcidin and Iron Metabolism (HERMES)

End-stage Renal Disease

Korea, Republic of
Association Pour La Recherche des Thérapeutiques...
Roche Pharma AG

Completed

Efficacy of Combination of Trastuzumab to Gemcitabine - Platinum Advanced or Metastatic Urothelial Carcinoma (CVH-CT02)

Recurrent Bladder Cancer | Stage IV Bladder Cancer | Transitional Cell Carcinoma of the Bladder

France, Belgium
Tony Bekaii-Saab
Roche Pharma AG

Completed

A Phase II Study of Capecitabine and Docetaxel in Previously Untreated Advanced Non-Small Cell Lung Cancer Patients

Lung Cancer | Non-Small-Cell Lung Carcinoma

United States
Centre Francois Baclesse
Roche Pharma AG; National Cancer Institute, France; Institut Curie

Completed

Safety Evaluation of a Combination of Brain Radiation Therapy and Bevacizumab (Avastin®) for Treatment of Brain Metastasis

Metastatic Malignant Neoplasm to Brain

France
Insel Gruppe AG, University Hospital Bern
University of Zurich; University Hospital, Geneva

Recruiting

Platelet Function After Cardiac Surgery. (PLFICS)

Platelet Dysfunction

Switzerland
Insel Gruppe AG, University Hospital Bern
Clinical Trials Unit University of Bern

Not yet recruiting

Closed Incision Negative Pressure Wound Therapy for the Prevention of Surgical Site Infections in Abdominal Surgery (CISSI)

Surgical Wound Infection

Switzerland
Seoul National University Bundang Hospital
Roche Pharma AG; Korean Cancer Study Group

Recruiting

KPMNG Study of MOlecular Profiling Guided Therapy Based on Genomic Alterations in Advanced Solid Tumors II (KOSMOSII)

Solid Tumor | Metastatic Cancer | Advanced Solid Tumor

Korea, Republic of
The Belgian Society of Medical Oncology
Roche Pharma AG; Foundation Medicine; Sciensano

Recruiting

A Study to Examine the Value of Broad Agnostic Next Generation Sequencing (NGS) Panel Testing Versus Reimbursed Organ-directed NGS: a Belgian Precision Study of the BSMO in Collaboration With the Cancer Center

Metastatic Cancer | Local Tumor Invasion

Belgium
Uppsala University
Roche Pharma AG; Perkin Elmer Inc.; Thermo Fisher Scientific, Inc

Completed

Study for Improving Maternal, Pregnancy and Child Outcomes (IMPACT)

Pre-Eclampsia

Sweden
Lia Bally
University Hospital, Basel, Switzerland

Completed

Fully Closed-Loop Insulin Delivery in Abdominal Surgery (CLAB) (CLAB)

Liver Diseases | Diabetes Mellitus, Type 2 | Gastric Disease | Colon Disease | Insulin Therapy | Pancreatic Disease | Perioperative Hyperglycaemia | Elective Surgery | Closed-Loop Glucose Control | Artificial Pancreas

Switzerland
Treatment and Diagnostic Center of Private Enterprise...
delta medical promotions ag

Active, not recruiting

"A Comparative Clinical Evaluation of the Efficacy of Topical Adapalene, Benzoyl Peroxide Gel, Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule, and Their Fixed Combination in Mild to Moderate Acne Vulgaris Patients."

Acne Vulgaris

Ukraine
Fraunhofer-Institute of Toxicology and Experimental...
M et P Pharma AG

Completed

Effect of the Nasal Gel "Nascum®-Plus" on Allergic Symptoms (NAPO)

Rhinitis, Allergic, Seasonal

Germany
German Breast Group
Roche Pharma AG; Amgen; Teva Pharmaceuticals USA; Vifor Pharma

Completed

A Phase III Trial Comparing Two Dose-dense, Dose-intensified Approaches (ETC and PM(Cb)) for Neoadjuvant Treatment of Patients With High-risk Early Breast Cancer (GeparOcto)

Inflammatory Breast Cancer | HER2 Positive Breast Cancer | Tubular Breast Cancer Stage II | Mucinous Breast Cancer Stage II | Breast Cancer Female NOS | Invasive Ductal Breast Cancer | Tubular Breast Cancer Stage III

Germany
Heart Centre Rotenburg
B. Braun Melsungen AG; Clinical Research Institute Rotenburg a.d.F.

Completed

Paclitaxel-Eluting Balloon Angioplasty and Coroflex™-Stents in the Treatment of Bifurcated Coronary Lesions (PEPCAD V)

Ischemia | Stenosis

Germany
Sponsor GmbH
GlaxoSmithKline; iOMEDICO AG; Arbeitsgemeinschaft fur Internistische Onkologie; Arbeitskreis Klinische Studien

Terminated

Dose Finding Study for Combination of Capecitabine, Lapatinib and Vinorelbine in Metastatic Breast Cancer (CELAVIE)

Metastatic Breast Cancer | HER2 Positive | First or Second Line Therapy | Failure or Contraindication of Trastuzumab Therapy

Germany
Dutch Colorectal Cancer Group
Sanofi; Roche Pharma AG; Koningin Wilhelmina Fonds; Immunicon

Completed

Cetuximab, Capecitabine, Oxaliplatin and Bevacizumab in Advanced Colorectal Cancer

Colorectal Cancer

Netherlands
University of Calgary
Canadian Institutes of Health Research (CIHR); Roche Pharma AG

Completed

Pegylated Interferon Plus Ribavirin in the Treatment of Active and Past Intravenous Drug Users Infected With Hepatitis C

Hepatitis c

Canada
University Hospital Southampton NHS Foundation...
Roche Pharma AG; Cancer Research UK

Recruiting

Atezolizumab Immunotherapy, in Immunotherapy Naive Patients With Urinary Tract Squamous Cell Carcinoma (UTSCC). (AURORA)

Squamous Cell Carcinoma | Urinary Tract Cancer

United Kingdom
Institut für Klinische Krebsforschung IKF GmbH...
Roche Pharma AG

Recruiting

PLATON - Platform for Analyzing Targetable Tumor Mutations (Pilot-study) (PLATON)

Stomach Cancer | Pancreatic Cancer | Cholangiocarcinoma | Gallbladder Cancer | Hepatocellular Cancer | Oesophageal Cancer

Germany
Pierre Fabre Pharma GmbH
Pierre Fabre Pharma Austria; Pierre Fabre Pharma AG

Recruiting

Binimetinib Plus Encorafenib Real Life Investigation of Next Generation Melanoma Treatment (BERING)

Melanoma Stage IV | Melanoma Stage III

Austria, Germany, Switzerland
Centre Hospitalier Intercommunal de Toulon La Seyne...
Hamilton Medical AG

Completed

Patient-ventilator Synchronisation Study for Intensive Care Unit Patients (SyncAutoVNI)

Acute Respiratory Failure

France
SOLTI Breast Cancer Research Group
Novartis; Roche Pharma AG; Guardant Health, Inc.

Active, not recruiting

Real World Study Using Comprehensive Genomic Data on the Next Treatment Decision Making in Metastatic Breast Cancer (HOPE)

Metastatic Breast Cancer

Spain
Charite University, Berlin, Germany
NeuroCure Clinical Research Center, Charite, Berlin; Brahms AG

Completed

Stroke Adverse Outcome is Associated With Nosocomial Infections: PCTus- Guided Antibacterial Therapy in Severe Ischemic Stroke Patients (STRAWINSKI) (STRAWINSKI)

Ischemic Stroke

Spain, Germany
ObsEva SA
Iqvia Pty Ltd; Cytel Inc.; Scope International AG; PhinC Development

Active, not recruiting

PoC Study of OBE022 in Threatened Preterm Labour (PROLONG)

Preterm Labor

Spain, Russian Federation, Vietnam, Czechia, Finland, Israel
A. Vogel AG
Cantonal Hospital of St. Gallen; Labormedizinisches Zentrum Dr. Risch

Completed

Superiority of Newly Developed Over Basic Echinacea Formulations for the Treatment of Respiratory Tract Infections

Respiratory Tract Infections

Switzerland
Advanced Osteotomy Tools (AOT) AG
Clinical Trial Unit, University Hospital Basel, Switzerland

Completed

First-In-Man Performance and Safety Evaluation of the CARLO® Device in Midface Osteotomies

Abnormalities, Jaw | Malocclusion, Angle Class III

Germany, Austria, Switzerland
Lindenhofgruppe AG
Lindenhofstiftung; Labormedizinisches Zentrum Dr. Risch; Clinical Trials Unit...

Completed

Preoperative Decolonization and Surgical Site Infections - a Prospective Randomized Trial (DECO-SSI)

Surgical Site Infection | Orthopedic Disorders

Switzerland
The Netherlands Cancer Institute
Merck Sharp & Dohme LLC; Roche Pharma AG; AstraZeneca

Unknown

Lung Cancer Early Molecular Assessment Trial (LEMA)

Carcinoma, Non-Small-Cell Lung

Netherlands
Seung-Jung Park
Roche Pharma AG; AstraZeneca; KBM pharm

Completed

Comparison of Low-Dose, Standard-Dose Ticagrelor and Clopidogrel for Inhibition of Platelet Reactivity in Patients With Acute Coronary Syndromes (OPTIMA)

Acute Coronary Syndrome

Korea, Republic of
University Hospital, Toulouse
Pfizer; Roche Pharma AG; Federation Francophone de Cancerologie Digestive

Completed

Metastatic Gastric Cancer FFCD 03-07

Stomach Cancer | Neoplasm Metastasis

France
University Hospital, Basel, Switzerland
Brahms AG; Basel Institute of Clinical Epidemiology (BICE)

Completed

Procalcitonin Guided Antibiotic Use in Acute Respiratory Tract Infections (PARTI)-Study

Respiratory Tract Infections

Switzerland
University of Bern
Kantonsspital Aarau; Kantonsspital Winterthur KSW; Kantonsspital Graubünden; Hospital... and other collaborators

Not yet recruiting

Stibium Metallicum Praeparatum 6x Versus Placebo in the Prevention of Paclitaxel-induced Peripheral Neurotoxicity (PROPEL NO TOX)

Chemotherapy Induced Peripheral Neuropathy (CIPN)
Universidade Federal de Goias
Institut Straumann AG; ITI International Team for Implantology, Switzerland

Not yet recruiting

Partially-guided Protocol for Maxillary Overdentures Retained by Ti-Zr One-piece Mini Implants (SMIS-Max)

Implant Complication | Edentulous Jaw
Insel Gruppe AG, University Hospital Bern
Swiss National Science Foundation; University of Bern

Recruiting

Magrolimab in Combination With Cytotoxic Chemotherapy in Advanced Urothelial Carcinoma (MACOCUC-01)

Advanced Urothelial Carcinoma

Switzerland
Medical University of Lodz
National Center for Research and Development, Poland; Senopi AG

Recruiting

VR for Improving Attention and Working Memory

Virtual Reality

Poland
Insel Gruppe AG, University Hospital Bern
Abbott; University Hospital, Zürich; Bangerter-Rhyner Stiftung

Recruiting

Implantable Cardiac Monitor to Detect Atrial Fibrillation in Patients With MINOCA (MINOCA)

Atrial Fibrillation | MINOCA

Switzerland
Nantes University Hospital
Roche Pharma AG; BioMérieux; ThermoFisher Scientific Brahms Biomarkers France; ...

Recruiting

Development of an Innovative Clinico-biological Score for the Early Detection of Acute Renal Failure Associated With Cardiac Surgery. (DETECT-AKI)

Acute Kidney Injury

France
Insel Gruppe AG, University Hospital Bern
Cystic Fibrosis Foundation; European Cystic Fibrosis Society

Recruiting

COVID-19 Antibody Responses In Cystic Fibrosis (CAR-CF)

Cystic Fibrosis

Switzerland
University Hospital, Geneva
Ospedale Regionale di Lugano; Insel Gruppe AG, University Hospital Bern

Recruiting

CT Scan Compared to CXR and LUS in Pneumonia in the Elderly (OCTOPLUS)

Pneumonia | Elderly Infection

Switzerland
crossklinik AG
University of Basel; Basel Academy for Quality and Research in Medicine

Completed

Return to Sports After ACLR (RTSACL)

Anterior Cruciate Ligament Injuries | Reconstruction

Switzerland
Insel Gruppe AG, University Hospital Bern
Swiss National Science Foundation; University of Bern

Completed

The PROAKTIV Study

Palliative Care

Switzerland
Queen Mary University of London
Roche Pharma AG; Barts & The London NHS Trust

Completed

Under and Over Rehabilitation Study

Multiple Sclerosis

United Kingdom
Rigshospitalet, Denmark
Merck Sharp & Dohme LLC; Roche Pharma AG; Beckett Foundation; Onkologisk Forskningsfond

Unknown

The Importance of Muscle Function in Patients With Disseminated Bladder Cancer

Urinary Bladder Neoplasm

Denmark
Spanish Cooperative Group for the Treatment of...
Roche Pharma AG

Completed

Influence of BRAF and PIK3K Status on the Efficacy of 5-Fluorouracil/Leucovorin/Oxaliplatin (FOLFIRI) Plus Bevacizumab or Cetuximab in Patients With RAS Wild-type Metastatic Colorectal Carcinoma and < 3 Circulating Tumor Cells (CTC) (VISNU-2)

Colorectal Cancer Metastatic

Spain
Association Aquitaine de Recherche Clinique en...
Roche Pharma AG; Chugai Pharma France

Completed

Characterization of the Effect of Tocilizumab in Vivo and in Vitro on T Follicular Helper Cells in Rheumatoid Arthritis Patients and Consequence on B Cells Maturation (Tocihelper)

Arthritis, Rheumatoid | Tocilizumab | T-Lymphocytes, Helper-Inducer

France

Clinical Trials Sponsored by HumanOptics AG

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