Clinical Trials Sponsored by Baker Heart Research Institute

Total 755 results

Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

The Efficacy and Cost-Effectiveness of Behavioral Counseling for Exercise in Men and Women Following Acute Myocardial Infarction (AMI) and Percutaneous Coronary Intervention (PCI)

Myocardial Infarction | Coronary Arteriosclerosis

Canada
Mario Negri Institute for Pharmacological Research
Bayer

Completed

Peripheral Artery Disease in Patients With Stable Coronary Artery Disease in General Practice: Prevalence, Management and Clinical Outcomes. (PAD&CAD)

Peripheral Artery Disease

Italy
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

Efficacy and Cost-Effectiveness of Cost-free Pharmacotherapy for Smoking Cessation for High-risk Smokers With Cerebrovascular Disease

Cerebrovascular Disorders | Smoking Cessation

Canada
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Canada

Completed

Family Heart Health Program: Randomized, Controlled Trial (FHHP-RCT)

Coronary Heart Disease

Canada
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

CPAP Therapy in Patients With Heart Failure and Obstructive Sleep Apnea. (PET-OSA)

Heart Failure | Obstructive Sleep Apnea

Canada
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

Varenicline Versus Transdermal Nicotine Patch for Smoking Cessation in Patients With Coronary Heart Disease

Coronary Heart Disease

Canada
Karolinska Institutet
Bayer; The Swedish Research Council

Completed

Exercise and Acarbose in Type 2 Diabetes

Diabetes Mellitus Type 2

Sweden
St. John's Research Institute
National Heart and Lung Institute

Completed

Secondary Prevention of coRonary Events After Discharge From Hospital (SPREAD) (SPREAD)

Acute Coronary Syndrome

India
University of Leicester
University Hospitals, Leicester; Loughborough University; Baker Heart and Diabetes...

Completed

The Effects of Reducing Prolonged Sitting Bouts in Individuals at High Risk of or With Type 2 Diabetes (UP FOR 5)

Type 2 Diabetes Mellitus

United Kingdom
Bayside Health
Monash University; Baker Heart and Diabetes Institute; Ambulance Victoria; FALCK...

Unknown

Air Verses Oxygen In myocarDial Infarction Study (AVOID)

Coronary Artery Disease | Acute Myocardial Infarction

Australia
Baker Heart and Diabetes Institute
The Alfred; Monash Medical Centre; Ballarat Health Services

Completed

Major Depressive Disorder - Understanding The Link Between The Brain And The Heart (MDD)

Major Depressive Disorder

Australia
Baker Heart and Diabetes Institute
The Alfred; Monash Medical Centre; Ballarat Health Services

Withdrawn

Alleviating the Metabolic Side Effects of Antipsychotic Medications

Schizophrenia

Australia
Montreal Heart Institute
Canadian Institutes of Health Research (CIHR); The Montreal Health Innovations... and other collaborators

Terminated

Blinded Randomized Trial of Anticoagulation to Prevent Ischemic Stroke and Neurocognitive Impairment in AF (BRAIN-AF)

ATRIAL FIBRILLATION

Canada
Carelon Research
National Heart, Lung, and Blood Institute (NHLBI); Jarvik Heart, Inc.

Active, not recruiting

Pumps for Kids, Infants, and Neonates (PumpKIN)

Pediatric Heart Failure

United States
Northern California Melanoma Center
Bayer; Melanoma Research Institute

Completed

GM-CSF as Adjuvant Therapy of Melanoma

Malignant Melanoma

United States
AusculSciences Canada Inc.
Ottawa Heart Institute Research Corporation

Unknown

Evaluating Auscul-X, a Touch Free Digital Stethoscope

COVID-19

Canada
AusculSciences Canada Inc.
Ottawa Heart Institute Research Corporation

Unknown

A Novel Non-Invasive Acoustic Diagnostic for the Diagnosis of Coronary Artery Disease The CAD-det Validation Study

Cardiovascular Diseases | Coronary Artery Disease | Atherosclerosis | Coronary Occlusion

Canada
Ottawa Heart Institute Research Corporation
Jubilant DraxImage Inc.

Completed

Rubidium Elution System Performance Testing (REST-PET)

Coronary Artery Disease

Canada
Ottawa Heart Institute Research Corporation
University of Toronto

Withdrawn

Left Internal Thoracic Artery Bypass Versus Percutaneous Revascularization in Diabetics (LIBERTI)

Coronary Artery Disease | Diabetes Mellitus
Ottawa Heart Institute Research Corporation
The Ottawa Hospital

Terminated

Relation of Carotid Artery Plaque Inflammation, Covert Stroke and White Matter Disease

Stroke | Carotid Artery Stenosis | TIA

Canada
Ottawa Heart Institute Research Corporation
Spartan Bioscience Inc.

Completed

Pharmacogenetic Approach to Anti-platelet Therapy for the Treatment of ST-segment Elevation Myocardial Infarction (STEMI) (RAPID STEMI)

STEMI

Canada
Aspirus Heart and Vascular Institute-Research and...

Completed

Effect of Ranolazine on Arrhythmias and Microvolt T- Wave Alternans (MVTWA) Patients With LV Dysfunction

Sudden Cardiac Death | Ventricular Arrythmias

United States
Ottawa Heart Institute Research Corporation
The Change Foundation

Completed

Using Automated Calls To Improve Compliance With Acute Coronary Syndrome Best Practice Guidelines

Medication Adherence | Acute Coronary Syndrome

Canada
Ottawa Heart Institute Research Corporation
Novartis; AstraZeneca; Servier

Recruiting

Improving Goal Directed Medical Therapy for Device Clinic Patients With Reduced EF at UOHI: a QI Initiative (VIGILANT) (VIGILANT)

Heart Failure

Canada
Ottawa Heart Institute Research Corporation
Jubilant DraxImage Inc.

Active, not recruiting

Dose Optimization for Rubidium PET Imaging in Patients With Known or Suspected Ischemic Heart Disease (RUBY-DOSE)

Ischemic Heart Disease

Canada
Ottawa Heart Institute Research Corporation
PAL Technologies Ltd.

Completed

Sedentary Intervention Trial in Cardiac Rehabilitation (SIT-CR)

Coronary Artery Disease

Canada
Ottawa Heart Institute Research Corporation
Schering-Plough; Medtronic

Completed

Safety and Efficacy Study of Eptifibatide in Primary Percutaneous Coronary Intervention (PCI)

Myocardial Infarction

Canada
National Heart Centre Singapore
Singapore Eye Research Institute

Not yet recruiting

JARVISDHL Screening Tools

Coronary Artery Disease

Singapore
Thiel, Alexander, M.D.
Ottawa Heart Institute Research Corporation

Recruiting

Contralesional Inhibitory rTMS for Recovery of Arm Function After Stroke (ConTRAstroke)

Feasibility Study

Canada
Ottawa Heart Institute Research Corporation
AFP Innovation Fund

Recruiting

Effect of a Hybrid Rehabilitation Program on Walking, Quality of Life & Cardiovascular Risk in People With PAD (HY-PAD)

Peripheral Arterial Disease

Canada
Ottawa Heart Institute Research Corporation
University of Calgary

Recruiting

Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance (TITAN:SvS)

Ascending Aorta Aneurysm | Ascending Aortic Aneurysm Enlargement

United States, Canada
Ottawa Heart Institute Research Corporation
Toronto General Hospital

Active, not recruiting

Early Post Transplant Cardiac Allograft Vasculopathy (ECAV)

Cardiac Allograft Vasculopathy

Canada
American Heart Association
Sanofi; Duke Clinical Research Institute

Active, not recruiting

Early Dronedarone Versus Usual Care to Improve Outcomes in Persons With Newly Diagnosed Atrial Fibrillation (CHANGE-AFIB)

Atrial Fibrillation

United States
Sakakibara Heart Institute
Japanese Foundation for Cancer Research

Completed

Pathogenic Mechanisms of Cancer and Cardiovascular Diseases

Cardiovascular Diseases | Cancer | Pathogenesis

Japan
Ottawa Heart Institute Research Corporation
Spartan Bioscience Inc.

Completed

ReAssessment of Anti-Platelet Therapy Using an InDividualized Strategy Based on GENetic Evaluation (RAPID GENE)

Acute Coronary Syndrome | Percutaneous Coronary Intervention | Stable Coronary Artery Disease

Canada
National Heart and Lung Institute
Nutricia Research Fundation

Completed

Enteral Nutrition in Congestive Heart Failure and Cardiac Cachexia

Chronic Heart Failure | Cardiac Cachexia

Poland, Germany
Mayo Clinic
National Cancer Institute (NCI); Miami Heart Research Institute

Recruiting

TrAstuzumab Cardiomyopathy Therapeutic Intervention With Carvedilol (TACTIC)

Breast Cancer

United States
Oregon Research Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Worksite Issues in Organizational Health Promotion (Take Heart)

Heart Diseases | Cardiovascular Diseases
Oregon Research Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Lifestyle Management for Women With CHD and NIDDM

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Diabetes Mellitus | Diabetes Mellitus, Non-insulin Dependent | Postmenopause
Oregon Research Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Enhancing Support for Women at Risk for Heart Disease

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Diabetes Mellitus, Non-insulin Dependent | Coronary Heart Disease Risk Reduction
Oregon Research Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Lifestyle Modification Program to Reduce Risk of Coronary Heart Disease in Latina Women With Diabetes

Heart Diseases | Cardiovascular Diseases | Diabetes Mellitus, Type 2

United States
Baylor Research Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Impact of Medical and Surgical Therapy on Functional Mitral Regurgitation

Heart Diseases | Cardiovascular Diseases | Coronary Disease

United States
Oregon Research Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Enhancing Support for Women With Type 2 Diabetes: Follow-Up

Type 2 Diabetes Mellitus

United States
Baker Heart and Diabetes Institute
Queen's University, Belfast; University of Melbourne; Heartwest; Western Health

Recruiting

Risk-guided Disease Management in Coronary Artery Disease (Risk-CAD)

Coronary Artery Disease | Chronic Disease | Nurse's Role

Australia
Montreal Heart Institute
Canadian Institutes of Health Research (CIHR); Abbott Medical Devices

Completed

Evaluation of Resynchronization Therapy for Heart Failure (EARTH) (EARTH)

Heart Failure

Canada
Montreal Heart Institute
Canadian Institutes of Health Research (CIHR); Abbott Medical Devices

Terminated

Evaluation of Resynchronization Therapy for Heart Failure (EARTH)

Heart Failure

Canada
Montreal Heart Institute
Canadian Institutes of Health Research (CIHR); Université de Montréal

Recruiting

ImproviNg rEnal Outcomes Following Coronary angiograPhy and/or percuTaneoUs coroNary intErventions (NEPTUNE)

Contrast-Induced Acute Kidney Injury

Canada
Population Health Research Institute
Bayer; University of Cape Town

Completed

INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, Non-Inferiority (INVICTUS-VKA)

Rheumatic Heart Disease

Botswana, Philippines, Zimbabwe, India, China, Egypt, Ethiopia, Uganda, Brazil, South Africa, Cameroon, Tanzania, Kenya, Zambia, Kazakhstan, Kyrgyzstan, Malawi, Mexico, Mozambique, Nepal, Nigeria, Pakistan, Paraguay, Rwanda, Sudan
H. Lee Moffitt Cancer Center and Research Institute
Bayer

Completed

Single Agent Regorafenib in Refractory Advanced Biliary Cancers

Cancer of the Bile Duct

United States
H. Lee Moffitt Cancer Center and Research Institute
Bayer

Completed

Copanlisib (BAY 80-6946) in Combination With Gemcitabine and Cisplatin in Advanced Cholangiocarcinoma

Cholangiocarcinoma | Gastrointestinal Tumor | Gall Bladder Carcinoma | Biliary Carcinoma

United States

Clinical Trials Sponsored by Baker Heart Research Institute

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