Clinical Trials Sponsored by CHEST Foundation

Total 16249 results

Shanghai Chest Hospital
Changhai Hospital; Ruijin Hospital

Unknown

Chemotherapy Plus Gefitinib for Advanced Lung Adenocarcinoma and Sensitive EGFR Mutations: a Randomized Controlled Trial

Lung Adenocarcinoma
Liverpool John Moores University
Liverpool Heart and Chest Hospital NHS Foundation Trust; Wirral Community Health...

Not yet recruiting

Exercise-based Cardiac Rehabilitation for Atrial Fibrillation (ExCR-AF)

Atrial Fibrillation
Shanghai Chest Hospital
Merck Sharp & Dohme LLC

Recruiting

A Study to Evaluate Pembrolizumab Plus Lenvatinib in PD-L1 Positive TKI Resistant NSCLC Patients

NSCLC

China
Geneplus-Beijing Co. Ltd.
Shanghai Chest Hospital

Recruiting

Therapeutic ResistAnce and Clonal Evolution Assessed With Liquid Biopsy in ICIs Treated NSCLC Patients

Lung Neoplasms | Adenocarcinoma of Lung | Lung Cancer, Nonsmall Cell | Squamous Cell Lung Cancer

China
Hutchison Medipharma Limited
Shanghai Chest Hospital

Completed

A Clinical Trial of Fruquintinib in Patients With Advanced Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

China
Royal Brompton & Harefield NHS Foundation Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust; National Institute...

Unknown

Catheter Ablation Versus Thoracoscopic Surgical Ablation in Long Standing Persistent Atrial Fibrillation (CASA-AF) (CASA-AF)

Persistent Atrial Fibrillation

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Brighton and Sussex University Hospitals NHS Trust; Liverpool Heart and Chest...

Completed

Long-term Outcomes in Long Standing Persistent Atrial Fibrillation (LoTO_CASA_AF)

Long Standing Persistent Atrial Fibrillation

United Kingdom
Neuroscience Trials Australia
National Institute for Health Research, United Kingdom; Northern Ireland Chest... and other collaborators

Completed

A Very Early Rehabilitation Trial (AVERT)

Stroke

Australia
Washington University School of Medicine
The Foundation for Barnes-Jewish Hospital; American College of Chest Physicians

Completed

Early Warning System

Diabetes Mellitus | Cancer | Chronic Obstructive Pulmonary Disease | Obstructive Sleep Apnea | Congestive Heart Failure

United States
Liverpool Heart and Chest Hospital NHS Foundation...
National Institute for Health Research, United Kingdom; Biolife LLC; The Johnson...

Terminated

Assessment of Radial Artery Complications Whilst Achieving Rapid Haemostasis (ARCH)

Injury; Blood Vessel, Wrist, Radial Artery

United Kingdom
Jinghui Wang

Recruiting

A Prospective, Single-arm, Phase II Clinical Trial to Evaluate the Efficacy and Safety of Tafolecimab and Sintilimab Combined With Chemotherapy in Patients With Advanced or Metastatic Driver Gene-negative Non-small Cell Lung Cancer After Failure of First-line Immunotherapy.

Lung Cancer

China
Shanghai Simnova Biotechnology Co.,Ltd.
Shanghai Chest Hospital

Recruiting

SNC115 Injections in Patients With Recurrent/Refractory Small Cell Lung Cancer and Lung Large Cell Neuroendocrine Carcinoma

Recurrent/Refractory Small Cell Lung Cancer Lung Large Cell Neuroendocrine Carcinoma

China
University of Rochester
American College of Chest Physicians

Recruiting

Home Rehabilitation After Acute Pulmonary Embolism

Pulmonary Embolism

United States
Jiangsu HengRui Medicine Co., Ltd.
Shanghai Chest Hospital

Unknown

Phase II Study of SHR-1210(Anti-PD-1 Antibody) Combination With Apatinib Versus Pemetrexed and Carboplatin in Subjects With KRAS Mutant Stage IV Non-squamous Non-small Cell Lung Cancer

Chemotherapy Effect | KRAS Gene Mutation | NSCLC Stage IV | PD-1 Antibody
Beijing Chest Hospital
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Mesylate Apatinib Combined With Irinotecan in Treatment of Recurrent Small Cell Lung Cancer

Small Cell Lung Cancer
Tianjin Chest Hospital
LinkDoc Technology (Beijing) Co. Ltd.

Completed

A Study to Explore Clinical Characteristics and Prognoses of N2 Patients With Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

China
Chang Gung Memorial Hospital
Taiwan Chest Disease Association

Completed

Influence of Prior Chemotherapy on Clinical Benefit With Erlotinib in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer With or Without EGFR Gene Mutation

Advanced Non-Squamous Non-Small Cell Lung Cancer

Taiwan
Chest Hospital, Ministry of Health and Welfare,...

Completed

Respiratory Rehabilitation Exercises in Older Adults With Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD)

Taiwan
Shanghai Chest Hospital
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

The Effect of Toripalimab Plus Radiotherapy in Patients With Operable Stage II-IIIA (N+) Non Small Cell Lung Cancer

NSCLC

China
Beijing Chest Hospital
Beijing Municipal Science & Technology Commission

Unknown

The Optimal Duration of Preoperative Anti-tuberculosis Treatment of Spinal Tuberculosis

Tuberculosis, Spinal

China
Hangzhou Broncus Medical Co., Ltd.
Shanghai Chest Hospital

Recruiting

Transbronchial vs Transthoracic Ablation for Early-stage Peripheral Lung Cancer

Stage IA Lung Cancer

China
Lady Reading Hospital, Pakistan
Pakistan Chest Society, Pakistan

Recruiting

Clopidogrel for the Prevention of Exacerbations in Severe COPD (CLOPEX)

COPD | COPD Exacerbation Acute

Pakistan
Beijing Chest Hospital
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Real-World Study of Pyrotinib Maleate in the Treatment of Advanced/Metastatic Non-Small Cell Lung Cancer With Rare Mutations in HER2

HER2 Mutant Non-small Cell Lung Cancer
Shanghai Chest Hospital
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Not yet recruiting

Almonertinib Treats Advanced NSCLC Patients With EGFR Mutations Who Are Safety Intolerant After Osimertinib Treatment (ACTIVE)

Lung Cancer | EGFR Gene Mutation
Liverpool University Hospitals NHS Foundation Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust; Countess of Chester... and other collaborators

Completed

The Risk of Major Bleeding With Novel Anti-platelets: A Comparison of Ticagrelor With Clopidogrel in a Real World Population of 5000 Patients Treated for Acute Coronary Syndrome (ROBOT-ACS)

Bleeding | Acute Coronary Syndrome | Ticagrelor | Clopidogrel | Novel Anti-platelets

United Kingdom
University of Chicago
American College of Chest Physicians; The John A. Hartford Foundation; Association...

Completed

Transfer to Another Health Care Facility Following Critical Illness

Transfer to a Health Care Facility After Critical Illness

United States
Barts & The London NHS Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust; Aortic Dissection...

Recruiting

Living With Marfans and Your Aorta: Surgical Outcomes Study (LIMA II)

Marfan Syndrome | Marfan Syndrome Cardiovascular Manifestations

United Kingdom
Beijing Chest Hospital
National Medical Center for Infectious Diseases

Recruiting

Innovating Shorter, All- Oral, Precised, Individualized Treatment Regimen for Rifampicin Resistant Tuberculosis：Contezolid, Delamanid and Bedaquiline Cohort (INSPIRE-CODA)

Pulmonary Tuberculosis | Rifampicin-resistant Tuberculosis

China
University of Ulster
Northern Ireland Chest Heart and Stroke

Completed

Children- Sit Less, Move More (C-SLAMM): Increasing Physical Activity and Decreasing Sedentary Behaviour in Children

Physical Activity | Child Behavior | Sedentary Behavior | Health Behavior | Physical Inactivity

United Kingdom
Shanghai University of Traditional Chinese Medicine
Shanghai Chest Hospital

Unknown

Efficacy Study of Chinese Medicine Plus EGFR-TKI Versus EGFR-TKI in Advanced Pulmonary Adenocarcinoma

Cancer
Barts & The London NHS Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust; Aortic Dissection...

Not yet recruiting

Mortality and Morbidity Outcomes in Marfans

Marfan Syndrome | Marfan Syndrome Cardiovascular Manifestations
Barts & The London NHS Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust; Aortic Dissection...

Completed

Living With Marfan Syndrome and Your Aorta (LIMA I)

Marfan Syndrome | Marfan Syndrome Cardiovascular Manifestations

United Kingdom
University of Ulster
Northern Ireland Chest Heart and Stroke

Completed

Prep Plus: Upper Limb Stroke Rehabilitation in the Community

Stroke

United Kingdom
Queen's University, Belfast
Northern Ireland Chest Heart and Stroke

Completed

SHARE-D: a Decision Tool to Help Patients Make Informed Lifestyle Choices (SHARE-D)

Health Behavior
University of Liverpool
Liverpool University Hospitals NHS Foundation Trust; Liverpool Heart and Chest... and other collaborators

Recruiting

A Platform Study for solId orgaN CancERs (PINCER)

Cancer | Surgery

United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...
Newcastle-upon-Tyne Hospitals NHS Trust; Imperial College Healthcare NHS Trust

Not yet recruiting

The RIPPLE AT-PLUS Study

Atrial Tachycardia

United Kingdom
Liverpool John Moores University
Liverpool Heart and Chest Hospital NHS Foundation Trust; University Hospitals... and other collaborators

Recruiting

Mobile Health for Cardiac Rehabilitation (Motivate-CR+)

Cardiac Event

United Kingdom
Ahi Evren Chest and Cardiovascular Surgery Education...

Completed

Physical Activity Level in Patients With OSAS During Covid-19 Pandemic

Obstructive Sleep Apnea-hypopnea Syndrome

Turkey
Tianjin Medical University Cancer Institute and...
Tianjin Chest Hospital

Recruiting

Serum Exosomal miRNA Predicting the Therapeutic Efficiency in Lung Squamous Carcinoma

Squamous Cell Carcinoma | Lung Neoplasm | Exosomes

China
Shanghai Chest Hospital
First Affiliated Hospital of Suzhou Medical College

Unknown

KN046 in Patients With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Pulse Medical Imaging Technology (Shanghai) Co....
Shanghai Chest Hospital

Unknown

Functional Diagnostic Accuracy of Quantitative Flow Ratio in Tandem Lesions and Virtual Stenting (FORTRESS)

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Vascular Diseases | Coronary Artery Disease | Arteriosclerosis | Arterial Occlusive Diseases

China
Ahi Evren Chest and Cardiovascular Surgery Education...

Unknown

Low Dose Prolonged Infusion of Tissue Type Plasminogen Activator Therapy in Massive Pulmonary Embolism

Pulmonary Embolism

Turkey
Liverpool John Moores University
University of Liverpool; Liverpool Heart and Chest Hospital NHS Foundation... and other collaborators

Recruiting

High-intensity Interval Training in Patients With Atrial Fibrillation (HIIT-AF)

Atrial Fibrillation

United Kingdom
Shanghai Jiao Tong University School of Medicine
Shanghai Chest Hospital

Recruiting

Limonene for Pulmonary Nodule Chemoprevention

Pulmonary Nodules

China
Zhigang Li
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Trial Of Neoadjuvant Chemotherapy or Radiochemotherapy With Or Without SHR-1210 In Patients With Resectable ESCC.

Locally Advanced Resectable Esophageal Squamous Cell Carcinoma

China
Baohui Han
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

Aumolertinib Adjuvant Therapy of Resectable Stage I EGFRm+ NSCLC With High-grade Patterns (APPOINT)

Lung Cancer

China
Ahi Evren Chest and Cardiovascular Surgery Education...

Completed

Validity and Reliability of the Turkish Version of Performance Measure for Activities of Daily Living-8

Congestive Heart Failure

Turkey
Shanghai Chest Hospital
First Affiliated Hospital of Chongqing Medical University

Unknown

The Efficacy and Safety of TBCB vs TBFB in Diagnosis of GGO

Lung Ground-Glass Opacity

China
Ahi Evren Chest and Cardiovascular Surgery Education...

Completed

Oropharyngeal Exercises and Inspiratory Muscle Training in Obstructive Sleep Apnea

Obstructive Sleep Apnea

Turkey
Berry Genomics Co., Ltd.
Shanghai Chest Hospital; Baotou Cancer Hospital

Unknown

cSMART Liquid Biopsy and Dynamic Monitor of NSCLC Patients in Inner-Mongolia China

Adenocarcinoma | Nonsmall Cell Lung Cancer

China

Clinical Trials Sponsored by CHEST Foundation

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Ecuador

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Rare Diseases

Drug Interventions

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