Clinical Trials Sponsored by Chesterfield Royal NHS Foundation Trust

Total 3534 results

Royal Brompton & Harefield NHS Foundation Trust

Unknown

Left Atrial Appendage Electrical Isolation and Occlusion to Treat Persistent Atrial Fibrillation: A Safety and Feasibility Study (LEIO-AF)

Persistent Atrial Fibrillation

United Kingdom
Royal Marsden NHS Foundation Trust
AstraZeneca

Unknown

Proof-of-Concept Study of AZD4547 in Patients With FGFR1 or FGFR2 Amplified Tumours (FGFR)

Breast Cancer | Gastric Cancer | Squamous Cell Carcinoma of the Lung | Oesophageal Cancer

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Withdrawn

Dysfunctional Breathing in Difficult Asthma.

Asthma

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Fibre Specific Signalling in the Locomotor Myopathy of Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Catheter Versus Thoracoscopic Surgical Ablation Strategy in Persistent Atrial Fibrillation (CASA-AF)

Persistent Atrial Fibrillation

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Early Percutaneous Coronary Intervention (PCI) After Fibrinolysis Versus Standard Therapy in ST Segment Elevation Myocardial Infarction (STEMI) Patients

Myocardial Infarction

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

Should Any One Airway Clearance Technique be Recommended for People With Cystic Fibrosis? (ACT)

Cystic Fibrosis
Royal Brompton & Harefield NHS Foundation Trust

Completed

Do Musculoskeletal Techniques Improve Forced Expiratory Volume in One Second in Adults With Cystic Fibrosis?

Cystic Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

The Diagnosis of Oral Allergy Syndrome Through the Use of a Structured Questionnaire

Food Allergy

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

Airway Clearance Using High Frequency Chest Wall Oscillation

Cystic Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
NHS Highlands

Completed

The Sunrise OSA Trial (SOSAT)

Obstructive Sleep Apnea

United Kingdom
Royal Marsden NHS Foundation Trust
Imperial College Healthcare NHS Trust

Completed

Primary Radiotherapy And DIEP flAp Reconstruction Trial (PRADA)

Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
Pelican Cancer Foundation

Unknown

Molecular, Pathologic and MRI Investigation of the Prognostic and Redictive Importance of Extramural Venous Invasion in Rectal Cancer (MARVEL) Trial (MARVEL)

Digestive System Diseases | Gastrointestinal Diseases | Neoplasms | Neoplasms by Histologic Type | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Gastrointestinal Neoplasms | Digestive System Neoplasms | Intestinal Diseases | Colorectal Neoplasms | Intestinal Neoplasms | Rectal... and other conditions

United Kingdom
Royal Marsden NHS Foundation Trust
Pelican Cancer Foundation

Unknown

Mri IN STaging REctal Polyp Planes (MINSTREL)

Rectal Cancer | Rectal Neoplasms | Colonic Polyps

United Kingdom
Royal Marsden NHS Foundation Trust
Pelican Cancer Foundation

Not yet recruiting

Pre-therapeutic MRI Assessment of Early Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery: A New Approach to the Management of Early Stage Rectal Cancer. (PRESERVE)

Rectal Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
Pelican Cancer Foundation

Unknown

Low Rectal Cancer Study (MERCURY II) (MERCURY II)

Digestive System Diseases | Gastrointestinal Diseases | Neoplasms | Neoplasms by Histologic Type | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Gastrointestinal Neoplasms | Digestive System Neoplasms | Intestinal Diseases | Colorectal Neoplasms | Intestinal Neoplasms | Rectal... and other conditions

United Kingdom, Germany, Serbia
Royal Marsden NHS Foundation Trust
Pelican Cancer Foundation

Completed

Surgical Anatomy and 'Waisting' of the sIgmoid SpEcimen (WISE)

Sigmoid, Sigmoid Colon, Neoplasm, Cancer

United Kingdom
Imperial College London
Royal Free Hospital NHS Foundation Trust; Royal Surrey County Hospital NHS...

Completed

MicroRNAs as Bile-based Biomarkers in Pancreaticobiliary Cancers (MIRABILE)

Pancreatic Cancer | Cholangiocarcinoma | Biliary Stricture | Gallstone Disease | Ampullary Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
Cambridge University Hospitals NHS Foundation Trust; University Hospital Plymouth...

Unknown

Tissue Collection for Biomarkers Determining Resistance to Ibrutinib (CLARITY)

Mantle Cell Lymphoma | Chronic Lymphocytic Leukaemia

United Kingdom
Royal Marsden NHS Foundation Trust
Janssen, LP

Recruiting

Impact of Apalutamide in Metastatic Hormone Sensitive Prostate Cancer Patients (ADAPT-P)

Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

United Kingdom
Royal Devon and Exeter NHS Foundation Trust

Not yet recruiting

Pulmonary Fibrosis Lung Sounds Study

Healthy | Pulmonary Fibrosis
Royal Surrey County Hospital NHS Foundation Trust

Not yet recruiting

Design and Evaluation of a Novel Methodology for SABR for Lung Cancer

Lung Cancer
Royal Surrey County Hospital NHS Foundation Trust

Recruiting

CIRcular and Non-coding RNAs as Clinically USeful Biomarkers in Pancreaticobiliary Cancers (CIRCUS)

Pancreatic Cancer | Biliary Tract Cancer

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust

Recruiting

Laparoscopic Surgery for Severe Recto-vaginal Endometriosis

Endometriosis Rectovaginal Septum

United Kingdom
Royal Devon and Exeter NHS Foundation Trust

Completed

Effect of Food Composition on Postprandial Insulin Secretion in Neonatal Diabetes (FoND)

Neonatal Diabetes

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust

Completed

PeRioperative Omega Three and the Effect on ImmuNity (PROTEIN)

Colorectal Cancer | Sarcopenia | Surgery | Surgery--Complications | Surgical Site Infection | Nutritional Deficiency | Complication, Postoperative | Infected Wound | Phagocytic Dysfunction

United Kingdom
Royal Free Hospital NHS Foundation Trust
Interreg

Completed

Virtual Rehabilitation Innovations for Motivation (VR4REHAB-MOT)

Brain Injuries | Children | Young Adult | CP (Cerebral Palsy) | Virtual Rehabilitation

United Kingdom
Royal Devon and Exeter NHS Foundation Trust

Completed

Timed Interval Measurement of Eotaxin in Stroke Study (TIMES)

Stroke, Acute

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust

Completed

Acute Kidney Injury - Biomarkers in Major Abdominal Surgery (AKI-BioMAS)

Acute Kidney Injury

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust

Unknown

Minimally Invasive Robotic Surgery, Role in Optimal Debulking Ovarian Cancer, Recovery & Survival (MIRRORS)

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer | Ovarian Neoplasm | Ovarian Neoplasm Epithelial

United Kingdom
Royal Berkshire NHS Foundation Trust
DePuy International

Suspended

Serum Metal Ion Levels in Patients Who Underwent Cathcart/Corail Hemiarthroplasty for Fractured Neck of Femur

Fractured Neck of Femur

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust

Terminated

Study to Evaluate the Role of PlasmaJet in Patients Undergoing Groin Node Dissection for Vulval Cancer

Vulvar Cancer | Groin Node

United Kingdom
Royal Marsden NHS Foundation Trust
Janssen, LP

Unknown

Proof-of-concept Study of Ibrutinib in c-MYC and HER2 Amplified Oesophagogastric Carcinoma (iMYC)

Gastrooesophageal Cancer

United Kingdom
Royal Devon and Exeter NHS Foundation Trust

Terminated

StartRIGHT: A Pilot Research Study About Diabetes Diagnosis & Treatment (StartRIGHT)

Diabetes
Royal Surrey County Hospital NHS Foundation Trust

Completed

3D Versus 4K Laparoscopic Cholecystectomy

Cholecystitis | Gallstones
Royal Surrey County Hospital NHS Foundation Trust

Unknown

Pain Associated With Interproximal Enamel Reduction in Orthodontics: a RCT (IER)

Orthodontic, Interproximal Enamel Reduction

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust

Unknown

Does Prehabilitation Improve Exercise Performance and Insulin Resistance After Surgery for Oesophago-gastric Cancer?

Cancer

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust

Completed

Investigating Three-Dimensional Versus Two-Dimensional Imaging in Laparoscopic Cholecystectomies

Gall Bladder Disease

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust

Unknown

Does Dietary Nitrate Supplementation Improve Aerobic Performance

Colorectal Cancer
Royal Brompton & Harefield NHS Foundation Trust
GlaxoSmithKline

Completed

IPF Drug Deposition Study (TOPICAL-IPF)

Idiopathic Pulmonary Fibrosis

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust

Unknown

Reducing Respiratory Side Effects of Interscalene Brachial Plexus Block

Adverse Reaction to Peripheral Nerve- and Plexus-blocking Anesthetics

United Kingdom
Royal Devon and Exeter NHS Foundation Trust

Completed

Singing Exercises to Improve Symptoms of Snoring and Sleep Apnea

Snoring | Obstructive Sleep Apnea | Upper Airway Resistance Syndrome

United Kingdom
ResMed
Royal Brompton & Harefield NHS Foundation Trust

Completed

AutoVPAP Versus VPAP; Assessment of Sleep and Ventilation

Neuromuscular Disease | Chest Wall Disorder

United Kingdom
Royal Marsden NHS Foundation Trust
Gilead Sciences

Not yet recruiting

Peri-operative Zimberelimab (Anti-PD-1) vs Zimberelimab in Combination With Domvanalimab (Anti-TIGIT) in Resectable Mismatch Repair Deficient/Micro-satellite Unstable Gastric and Gastro-oesophageal Junctional Adenocarcinoma (ZODIAC) (ZODIAC)

Metastatic Gastric Cancer | Metastatic Esophageal Cancer
Royal Marsden NHS Foundation Trust
European Commission

Recruiting

Investigating National Solutions for Personalised Iodine-131 Radiation Exposure (INSPIRE)

Differentiated Thyroid Cancer

United Kingdom
Royal Devon and Exeter NHS Foundation Trust

Active, not recruiting

Defining the Decline in Endogenous Insulin Secretion in Type 1 Diabetes Diagnosed After 30 Years of Age. (DROPLeT)

Diabetes Mellitus, Type 1 | Progression

United Kingdom
Royal Devon and Exeter NHS Foundation Trust

Completed

Timing of Suture Removal to Reduce Scarring in Skin Surgery

Suture Related Complication

United Kingdom
Royal Marsden NHS Foundation Trust
Innovate UK

Active, not recruiting

Evaluating a Digital Tool for Supporting Breast Cancer Patients (ADAPT)

Breast Cancer

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust

Completed

Oral Assessment of Symptoms in Advanced Cancer (OASis)

Cancer | Oral Complication

United Kingdom
Royal Marsden NHS Foundation Trust
Celgene Corporation

Active, not recruiting

Phase II Study Comparing LR-GEM to R-GEM-P in Second-line Treatment of Diffuse Large B-cell Lymphoma (LEGEND) (LEGEND)

Diffuse Large B-Cell Lymphoma

United Kingdom

Clinical Trials Sponsored by Chesterfield Royal NHS Foundation Trust

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