Clinical Trials Sponsored by Gordon and Betty Moore Foundation

Total 475 results

Queen Mary University of London
Guy's and St Thomas' NHS Foundation Trust; Barts & The London NHS Trust; Royal... and other collaborators

Active, not recruiting

Implementing Long-Acting Novel Antiretrovirals (ILANA)

Human Immunodeficiency Viruses

United Kingdom
Royal United Hospitals Bath NHS Foundation Trust
Sheffield Teaching Hospitals NHS Foundation Trust; Royal Free Hospital NHS... and other collaborators

Recruiting

Improving Pulmonary Hypertension Screening by Echocardiography (IMPULSE)

Pulmonary Hypertension

United Kingdom
The Lifebox Foundation
Johns Hopkins University; University College, London; Bill and Melinda Gates... and other collaborators

Completed

Development of a Robust and Reliable Pulse Oximeter for Children With Pneumonia in Low-income Countries

Pneumonia in Children | Measurement of Peripheral Oxygen Saturation

United Kingdom, Bangladesh, Malawi
Lightpoint Medical Limited
King's College London; Guy's and St Thomas' NHS Foundation Trust

Unknown

The Breast Surgery EnLight and LightPath Imaging System Study

Breast Neoplasms

United Kingdom
King's College London
Guy's and St Thomas' NHS Foundation Trust; Action Medical Research

Recruiting

Developing Advanced Neuroimaging for Clinical Evaluation of Autoimmune Encephalitis (DANCE-AE)

Autoimmune Encephalitis | Anti-N-Methyl-D-Aspartate Receptor Encephalitis

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; Massachusetts General Hospital

Recruiting

Personalised Responses to Dietary Composition Trial (PREDICT)

Heart Diseases | Healthy | Obesity | Diabetes | Diet Modification | Microbial Colonization | Diet Habit | Metabolism

United Kingdom
Sangath
London School of Hygiene and Tropical Medicine; Public Health Foundation of...

Completed

Extended Evaluation of School-based Health Promotion Programmes in Bihar, India (SEHER+)

Health Promotion

India
King's College London
Cancer Research UK; Guy's and St Thomas' NHS Foundation Trust

Unknown

Assay Development for Cancer Biomarkers

Tumors

United Kingdom
Lightpoint Medical Limited
King's College London; Guy's and St Thomas' NHS Foundation Trust

Completed

LightPathTM Imaging System for Ex-vivo Assessment of Margin and Lymph Node Status in Breast Cancer Surgical Specimens

Breast Cancer

United Kingdom
Imperial College London
Medical Research Council; University of Oxford; Guy's and St Thomas' NHS Foundation... and other collaborators

Completed

Research In Viral Eradication of HIV Reservoirs (RIVER)

HIV

United Kingdom
King's College London
South London and Maudsley NHS Foundation Trust; South West London and St George... and other collaborators

Unknown

Social Information Processing in Adolescents With Eating Disorders

Eating Disorders in Adolescence

United Kingdom
Imperial College London
Bill and Melinda Gates Foundation; University of Oxford; Rockefeller University

Recruiting

A Randomised Placebo Controlled Trial of ART Plus Dual Long-acting HIV-specific Broadly Neutralising Antibodies (bNAbs). (RIO)

HIV/AIDS and Infections

Denmark, United Kingdom
University of Surrey
Uppsala University; Central and North West London NHS Foundation Trust

Terminated

Reducing Intrusive Memories in Refugees and Asylum Seekers With PTSD

Stress Disorders, Traumatic | Stress Disorders, Post-Traumatic | Trauma and Stressor Related Disorders | Post Traumatic Stress Disorder | Mental Disorder | Trauma, Psychological

United Kingdom
Sangath
London School of Hygiene and Tropical Medicine; Public Health Foundation of...

Completed

Evaluation of School-based Health Promotion Programmes in Bihar, India (SEHER)

Health Promotion

India
University of Surrey
Uppsala University; Central and North West London NHS Foundation Trust

Terminated

Reducing Intrusive Memories in Refugees and Asylum Seekers With PTSD: A Pilot Study

Stress Disorders, Traumatic | Stress Disorders, Post-Traumatic | Trauma and Stressor Related Disorders | Mental Disorder

United Kingdom
King's College London
Guy's and St Thomas' NHS Foundation Trust; Integra LifeSciences Corporation

Unknown

Evaluating Outcomes of Immediate Breast Reconstruction (POBRAD-M) (POBRAD-M)

Breast Neoplasms | Breast Diseases

United Kingdom
Royal College of Music
Imperial College London; Chelsea and Westminster NHS Foundation Trust

Completed

The Impact of Creative Interventions on Symptoms of Postnatal Depression

Depression, Postpartum

United Kingdom
University of Liverpool
University of Leeds; Liverpool John Moores University; Liverpool Heart and Chest... and other collaborators

Terminated

The Effects of Renal Function and Atrial Fibrillation on Lipoproteins and Clot Structure/Function (RALiC)

Atrial Fibrillation | Chronic Kidney Disease

United Kingdom
King's College London
Imperial College London; Medical Research Council; Guy's and St Thomas' NHS Foundation... and other collaborators

Unknown

Treg Immunotherapy in Crohn's Disease (TRIBUTE)

Crohn Disease
University College, London
Norfolk and Norwich University Hospitals NHS Foundation Trust; The Christie... and other collaborators

Recruiting

VideoEndoscopic Radical Inguinal Lymphadenectomy for Penile Cancer (VELRAD)

Melanoma | Penile Cancer | Inguinal Lymphadenopathy

United Kingdom
King's College London
Guy's and St Thomas' NHS Foundation Trust; Brighton and Sussex University Hospitals...

Recruiting

A Study to Measure the Expression of the HER2-HER3 Dimer in Tumour and Blood (Exosomes) Samples From Patients With HER2 Positive Breast Cancer Receiving HER2 Targeted Therapies (HERdi PREDICT)

HER2-positive Breast Cancer

United Kingdom
King's College Hospital NHS Trust
Barts and the London School of Medicine and Dentistry; Fetal Medicine Foundation

Unknown

The BEET-BP Trial - Investigating the Effect of Dietary Nitrates on Hypertension in Pregnancy

Pre-Eclampsia | Hypertension in Pregnancy | Gestational Hypertension | Pregnancy Induced Hypertension

United Kingdom
King's College London
Royal Free Hospital NHS Foundation Trust; Chelsea and Westminster NHS Foundation... and other collaborators

Recruiting

Muscle Connective Tissue in Limb Development and Disease

Radial Dysplasia

United Kingdom
Origin Sciences
Queen Mary University of London; Royal Devon and Exeter NHS Foundation Trust

Recruiting

Feasibility Study to Investigate Rectal Mucus in Aero-Digestive Tract Cancer. (ORI-EGI-03)

Pancreatic Cancer | Gastric Adenocarcinoma | Non Small Cell Lung Cancer | Bladder Cancer | Gall Bladder Cancer

United Kingdom
NanoMab Technology (UK) Limited
King's College London; Guy's and St Thomas' NHS Foundation Trust

Recruiting

PD-L1 Expression in Lung Cancer (PELICAN)

Non-Small Cell Lung Cancer

United Kingdom
Lawson Health Research Institute
London Health Sciences Foundation; Ontario Ministry of Colleges and Universities

Recruiting

Annexin A5 in Patients With Severe COVID-19 Disease (AX-COVID)

Coronavirus Infection | Sepsis

Canada
University of Sheffield
Sheffield Health and Social Care NHS Foundation Trust; Howard Morton Trust

Completed

Reducing Stasis Outcomes for Depression in Group Behavioural Activation Therapy

Depression

United Kingdom
Public Health Foundation of India
London School of Hygiene and Tropical Medicine; Wellcome Trust

Completed

mWELLCARE:An Integrated mHealth System for the Prevention and Care of Chronic Disease (mWELLCARE)

Depression | Hypertension | Diabetes | Alcohol Use Disorder

India
Royal Holloway University
Barts & The London NHS Trust; Chelsea and Westminster NHS Foundation Trust

Not yet recruiting

Exploring a Digital HIV Onward Disclosure Intervention, in People Living With HIV of Sub-Saharan African Ethnicity.

Hiv
Guy's and St Thomas' NHS Foundation Trust
King's College London; Sir Halley Stewart Trust

Completed

Thinking Outside the Box

Medication Adherence | Medication Compliance | Attitude | Caregivers

United Kingdom
London School of Hygiene and Tropical Medicine
Sangath; University College, London; University of Liverpool; Human Development...

Unknown

SPRING Cluster Randomised Controlled Trial (SPRING)

Death | Depression, Postpartum | Child Development | Growth; Stunting, Nutritional

India, Pakistan
Royal Devon and Exeter NHS Foundation Trust
King's College London; Leiden University Medical Center

Completed

Type 1 Diabetes, Immunology, Genetics & Endogenous Insulin Production (TIGI)

Type 1 Diabetes Mellitus

Netherlands, United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; The Dunhill Medical Trust

Unknown

Motivating Structured Walking Activity in Intermittent Claudication (MOSAIC)

Peripheral Arterial Disease | Intermittent Claudication | Peripheral Vascular Disease

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
City, University of London; University of Exeter

Completed

PRediction of Outcome With ED Intervention for Colles Type Wrist Fractures [PREDICT] (PREDICT)

Colles' Fracture | Colles' Fracture of Unspecified Radius, Sequela

United Kingdom
King's College London
University of Sheffield; University of Edinburgh; South London and Maudsley NHS... and other collaborators

Completed

Comparing Different Treatments in Reducing Dissociative Seizure Occurrence (CODES)

Conversion Disorder | Dissociative Disorder | Convulsion, Nonepileptic

United Kingdom
London School of Hygiene and Tropical Medicine
Barts & The London NHS Trust; St George's University Hospitals NHS Foundation... and other collaborators

Completed

The Trauma INtramuscular Tranexamic Acid Clinical Trial (TraumaINTACT)

Traumatic Haemorrhage

United Kingdom
Imperial College London
Chelsea and Westminster NHS Foundation Trust; Royal Brompton & Harefield NHS... and other collaborators

Recruiting

PROSAIC-19 - Prospective Longitudinal Assessment in a COVID-19 Infected Cohort (PROSAIC-19)

COVID-19 | SARS-CoV 2 | ARDS, Human | Immune System Disorder

United Kingdom
University College, London
King's College London; Imperial College London; National Institute for Health... and other collaborators

Unknown

Dementia Early Recognition and Response in Primary Care (EVIDEM-ED)

Dementia

United Kingdom
University of Bath
South London and Maudsley NHS Foundation Trust; Avon and Wiltshire Mental Health...

Unknown

Examining the Feasibility and Acceptability of Good Quality Intensive CBT for OCD and Good Quality Weekly CBT for OCD

Obsessive Compulsive Disorder (OCD)

United Kingdom
London School of Hygiene and Tropical Medicine
Bill and Melinda Gates Foundation; Population Council; International Planned...

Completed

Benefits and Costs of Integrating Sexual-Reproductive Health and HIV Services in Kenya and Swaziland (Integra)

Pregnancy | HIV

Kenya, Swaziland
London School of Hygiene and Tropical Medicine
Bill and Melinda Gates Foundation; Centers for Disease Control and Prevention; Ifakara Health Institute

Unknown

IMPACT2: Monitoring Interventions to Improve Artemisinin-based Combination Therapy (ACT) Access and Targeting (IMPACT2)

Malaria | Anaemia

Tanzania
Guy's and St Thomas' NHS Foundation Trust
London School of Hygiene and Tropical Medicine; King's College London; King's... and other collaborators

Completed

A Randomised Trial of Expedited Transfer to a Cardiac Arrest Centre for Non-ST Elevation Out-of-hospital Cardiac Arrest (ARREST)

Out-Of-Hospital Cardiac Arrest

United Kingdom
King's College London
Imperial College London; Guy's and St Thomas' NHS Foundation Trust; University... and other collaborators

Not yet recruiting

Enhancing Sensorimotor Processing in Children With Dystonia

Dystonia | Dystonia; Idiopathic | Dystonia, Primary | Dystonia, Secondary | Dystonic Cerebral Palsy
Cambridge University Hospitals NHS Foundation Trust
The Gurdon Institute; Ann McLaren Laboratory of Regenerative Medicine

Unknown

In Vitro Models of Liver and Pancreatic Cancer

Hepatocellular Carcinoma | Cholangiocarcinoma | Pancreatic Neoplasm

United Kingdom
Imperial College London
Royal Free Hospital NHS Foundation Trust; Mid and South Essex NHS Foundation... and other collaborators

Recruiting

Finding the Invasive Haemodynamic Threshold for Symptom Relief in Stable Angina (ORBITA-FIRE)

Stable Angina

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; Imperial College London; National Institute for Health...

Completed

The Grown Up Peanut Immunotherapy Study (GUPI)

Peanut Allergy

United Kingdom
Imperial College London
Guy's and St Thomas' NHS Foundation Trust; Imperial College Healthcare NHS...

Recruiting

Assessment, Monitoring and Optimisation of Prehabilitation Patients Using Wearable Fitness Trackers

Cancer

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; King's College Hospital NHS Trust

Recruiting

Predicting the Risk of Non-culprit Coronary Artery Disease After a Heart Attack (OCT-RISK)

Coronary Artery Disease | ST Elevation Myocardial Infarction | Ischemic Heart Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; Newcastle University; University of Cambridge

Completed

XPAND Trial: Enhancing XP Photoprotection Activities - New Directions (XPAND)

Xeroderma Pigmentosum

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; Cardiff University; University of Surrey

Completed

Proof of Concept Study for a Dressing Glove

Epidermolysis Bullosa Dystrophica

United Kingdom

Clinical Trials Sponsored by Gordon and Betty Moore Foundation

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