Clinical Trials Sponsored by Hjartavernd, Iceland

Total 1337 results

Tibotec Pharmaceuticals, Ireland

Completed

TMC278-TiDP38-C145: A Bioavailability Study in Healthy Adult Volunteers to Evaluate 3 Pediatric Formulations of TMC278 (a Solution, a Suspension, and Granules) Compared to an Adult Tablet Formulation

Pharmacokinetics | Bioavailability | HIV-1
Tibotec Pharmaceuticals, Ireland

Completed

TMC278-TiDP6-C152: A Study to Assess the Effects of TMC278 and Efavirenz (EFV) on the QT/QTc Interval (Heart Conduction and Heart Rhythm) in Healthy Volunteers.

Human Volunteers
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-TiDP2-C197: A Phase I Trial to Investigate the Pharmacokinetic Interaction Between Lopinavir/Ritonavir and TMC125 Both at Steady-state in Healthy Volunteers.

HIV
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-TiDP3-C181: Study to Assess the Pharmacokinetics of Darunavir (DRV) With Different Doses of Ritonavir in Healthy Volunteers.

HIV | AIDS
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-TiDP2-C188: A Phase I, Open-label Trial to Investigate the Pharmacokinetic Effect of Multiple-dose TMC125 on Buprenorphine and Norbuprenorphine Administered in HIV-negative Patients on Stable Buprenorphine/Naloxone Maintenance Therapy.

HIV | Pharmacokinetics
Tibotec Pharmaceuticals, Ireland

Completed

TMC435350-TiDP16-C101 - A Study to Examine the Safety, Tolerability and Pharmacokinetics of Increasing Oral Doses of TMC435350 After Single and Repeated Dosing

Hepatitis C
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-C201: A Study to Determine the Antiviral Activity of TMC114 in Patients With Multiple Protease Inhibitor (PI) Resistant Human Immunodeficiency Virus (HIV) Strains

HIV Infections
Tibotec Pharmaceuticals, Ireland

Terminated

TMC278-TiDP15-C150: Trial to Examine Safety, Tolerability and Plasma Pharmacokinetics of Multiple Doses of TMC278LA.

HIV-1
Tibotec Pharmaceuticals, Ireland

Completed

TMC435-TiDP16-C121: A Study Comparing 2 Tablet Formulations of TMC435 to an Established Capsule Formulation and Evaluating the Effect of Food on Blood Levels of TMC435

Hepatitis C Virus
Tibotec Pharmaceuticals, Ireland

Completed

PEPI-TiDP23-C103: First-in-Human Study to Examine the Safety, Tolerability, and Plasma Pharmacokinetics of Increasing Single and Repeated Oral Doses of TMC558445 and of a Combined Single Day Dosing of Oral TMC558445 and Oral TMC310911 and Also Oral Darunavir

HIV-1
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-C203: Phase II Randomized (Patients Are Assigned Different Treatments Based on Chance), Placebo Controlled Dose Escalating Trial of TMC125 in HIV-1 Infected Patients

HIV-1 | Anti-Retroviral Agents
Tibotec Pharmaceuticals, Ireland

Completed

TMC278-TiDP6-C130: Pharmacokinetics, Safety and Tolerability of TMC278 in Subjects With Mildly or Moderately Impaired Hepatic Function.

HIV | Hepatic Impairment | AIDS
Tibotec Pharmaceuticals, Ireland

Completed

TMC435350-TiDP16-C109: A Safety Study for TMC435350 in an Oral Solution Containing Either 100, 200 or 400 mg Equivalent of TMC435350 or Placebo in Healthy Japanese Male Volunteers

HCV
Queen's University, Belfast
National University of Ireland, Galway, Ireland; Royal College of Surgeons,...

Unknown

Anticipatory Care Planning Intervention for Older Adults at Risk of Functional Decline: A Primary Care Feasibility Study

Aging

United Kingdom
St. James's Hospital, Ireland
Royal College of Surgeons, Ireland

Not yet recruiting

RADA16 for Reducing Drain Output Trajectory Following Neck Dissection (ROUND)

Head and Neck Cancer
Horizon Therapeutics, LLC

Completed

Study of Glycerol Phenylbutyrate & Sodium Phenylbutyrate in Phenylbutyrate Naïve Patients With Urea Cycle Disorders (UCDs)

Urea Cycle Disorder

United States, Spain, Italy, Switzerland
Horizon Pharma Ireland, Ltd., Dublin Ireland
Ucyclyd Pharma, Inc.

Completed

A Study of Glyceryl Tri-(4-phenylbutyrate) (GT4P)

Healthy

Ukraine
Royal College of Surgeons, Ireland
Health Research Board, Ireland

Unknown

Penicillin for the Emergency Department Outpatient Treatment of CELLulitis (PEDOCELL)

Abscess | Cellulitis | Wound Infection

Ireland
National University of Ireland, Galway, Ireland
Irish Research Council; Mid Western Regional Hospital, Ireland

Completed

Neuromuscular Electrical Stimulation Following Total Hip Arthroplasty

Deep Vein Thrombosis | Total Hip Arthroplasty

Ireland
Universita di Verona
National University of Ireland, Galway, Ireland

Recruiting

IVUS Analysis for Coronary Obstruction in TAVI (ICARO)

Coronary Artery Occlusion

Italy
National University of Ireland, Maynooth
Hermitage clinic, Lucan, Ireland

Completed

Tinnitus Alleviation Via Sensory Stimulation

Tinnitus
Horizon Therapeutics, LLC

Terminated

Observational Study That Will Collect Information on Patients With Urea Cycle Disorders (UCDs) (THRIVE)

Urea Cycle Disorder

United States
Horizon Therapeutics, LLC

Completed

A Study of the Safety, Efficacy and Pharmacokinetics of Glycerol Phenylbutyrate in Pediatric Subjects Under 2 Years of Age With Urea Cycle Disorders

Urea Cycle Disorder

United States, Canada
University of Pittsburgh
Horizon Pharma Ireland, Ltd., Dublin Ireland

Completed

Use of Ravicti™ in Patients With MCAD Deficiency With the 985A>G (K304E) Mutation

Medium-chain Acyl-CoA Dehydrogenase (MCAD) Deficiency

United States
Horizon Pharma Ireland, Ltd., Dublin Ireland
Ucyclyd Pharma, Inc.

Completed

A Study of Glyceryl Tri-(4-phenylbutyrate) Administered Orally as a Single Dose, and Twice Daily for Seven Consecutive Days to Subjects With Hepatic Impairment With Cirrhosis and to a Control Group

Hepatic Encephalopathy | Urea Cycle Disorders

Ukraine
National University of Ireland, Galway, Ireland
Irish Research Council

Completed

Neuromuscular Electrical Stimulation Versus Intermittent Pneumatic Compression for Blood Flow

Venous Thrombosis

Ireland
Beaumont Hospital
GlaxoSmithKline; Health Research Board, Ireland; Asthma Society Ireland; Irish... and other collaborators

Completed

A Study of Inhaler Use in the Community

Chronic Obstructive Pulmonary Disease | Asthma | Airways Disease

Ireland
Royal College of Surgeons, Ireland
St. James's Hospital, Ireland

Completed

Lower Limb Resistance Training in Older Inpatients

Muscle Weakness

Ireland
Singapore General Hospital
National University of Ireland, Galway, Ireland

Unknown

Compression Stockings Therapy Following Mechano-Chemical Ablation (Clarivein®) (COMMOCA)

Varicose Veins | Chronic Venous Insufficiency

Singapore, Ireland
Royal College of Surgeons, Ireland
Health Research Board, Ireland

Completed

Topical Glyceryl Trinitrate (GTN) and Eccentric Exercises in the Treatment of Midportion Achilles Tendinopathy (NEAT)

Tendinopathy | Achilles Tendon Pain

Ireland
Royal College of Surgeons, Ireland
Health Research Board, Ireland

Unknown

IRELAnD: Investigating the Role of Early Low-dose Aspirin in Diabetes (IRELAnD)

Pre-Gestational Diabetes
Horizon Therapeutics, LLC

Completed

To Evaluate the Safety of Long-term Use of HPN-100 in the Management of Urea Cycle Disorders (UCDs)

Urea Cycle Disorders

United States, Canada
National University of Ireland, Galway, Ireland
Irish Research Council

Unknown

Feasibility of a Physical Activity Programme for Older Adults in Nursing Homes

Old Age
National University of Ireland, Galway, Ireland
Irish Endocrine Society

Completed

Exogenous Glucose Oxidation Breath Test (EGOBT)

Diabetes Mellitus, Type 2

Ireland
University of Pennsylvania
University of Iceland

Recruiting

Metabolomics of Obstructive Sleep Apnea (MOSA)

Obstructive Sleep Apnea

United States, Iceland
University of Iceland
Landspitali University Hospital

Not yet recruiting

Meals, Microbiota & Mental Health of Children & Adolescents (MMM)

Mental Disorder
University of Iceland
Landspitali University Hospital

Active, not recruiting

Polypharmacy and Associated Risk Factors and Clinical Outcomes for Surgical Patients Discharged From Hospital

General Surgery | Polypharmacy

Iceland
University of Iceland
University of Aarhus

Completed

Mindfulness Based Cognitive Therapy (MBCT) for Primary Care Patients

Depression, Anxiety

Iceland
University of Pennsylvania
University of Iceland

Completed

The Effects of Treating Obese and Lean Patients With Sleep Apnea (PISA)

Obesity | Sleep Apnea

United States
Landspitali University Hospital
University of Iceland

Completed

Obstetric Perineal Trauma and Physiotherapy

Pregnancy Complications

Iceland
Landspitali University Hospital
University of Iceland

Completed

Being Awake, Upright and Moving as the Basis for Early ICU Physiotherapy

Critical Illness

Iceland
Rigshospitalet, Denmark
University of Iceland; Octapharma

Completed

Vasculopathic Injury and Plasma as Endothelial Rescue in Septic Shock (SHOCK) Trial (VIPER-SHOCK)

Septic Shock

Denmark
University of Iceland
Landspitali University Hospital

Completed

FAM-SOTC Intervention for Families of Children With Chronic Illnesses

Chronic Illnesses
University of Limerick
National University of Ireland, Galway, Ireland; University of Ulster; Ulster...

Completed

The Effect of Natural Food Flavourings on Gastrointestinal and Cardiovascular Physiological Responses. (CinnGastEmpt)

Diabetes Mellitus | Gastric Emptying

Ireland
Attune Health Research, Inc.
Horizon Pharma Ireland, Ltd., Dublin Ireland

Active, not recruiting

Assessing the Role of the NLRP3 Inflammasome in Intercritical Gout

Gout

United States
Shannon Hernon
Galway Clinic

Unknown

The Effect of Structured Exercise on Chronic Venous Insufficiency (CVI)

Chronic Venous Insufficiency

Ireland
Horizon Pharma Ireland, Ltd., Dublin Ireland
Friedreich's Ataxia Research Alliance

Completed

Long-Term Safety Extension Study of ACTIMMUNE® (Interferon γ-1b) in Children and Young Adults With Friedreich's Ataxia (STEADFAST)

Friedreich's Ataxia

United States
National University of Ireland, Galway, Ireland
University College Hospital Galway

Completed

Effects of Remote Ischemic Preconditioning on Moderate PVD Patients A Pilot Randomized Control Trial (RIPC-PVD)

Peripheral Arterial Diseases

Ireland
National University of Ireland, Galway, Ireland
GE Healthcare; HeartFlow, Inc.

Recruiting

Safety and Feasibility Evaluation of Planning and Execution of Surgical Revascularization Solely Based on Coronary CTA and FFRCT in Patients With Complex Coronary Artery Disease (FASTTRACK CABG)

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Vascular Diseases | Coronary Artery Disease | Coronary Disease | Arteriosclerosis | Arterial Occlusive Diseases

Italy, Belgium, Germany
National University of Ireland, Galway, Ireland
University Hospital of Limerick

Completed

Autologous Stem Cells for the Treatment of No Option Critical Limb Ischemia

Critical Limb Ischemia

Ireland

3

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