Clinical Trials Sponsored by Sorin Group Canada

Total 366 results

NCIC Clinical Trials Group
National Cancer Institute (NCI)

Completed

Sorafenib in Treating Patients With Metastatic or Recurrent Prostate Cancer

Prostate Cancer

Canada
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; Canadian Cancer Trials Group; Southwest Oncology... and other collaborators

Completed

Doxorubicin Hydrochloride, Cyclophosphamide, and Pacltaxel With or Without Trastuzumab in Treating Women With HER2-Positive Node-Positive or High-Risk Node-Negative Breast Cancer

HER2 Positive Breast Carcinoma | Stage IA Breast Cancer AJCC v7 | Stage IB Breast Cancer AJCC v7 | Stage IIA Breast Cancer AJCC v6 and v7 | Stage IIB Breast Cancer AJCC v6 and v7 | Stage IIIA Breast Cancer AJCC v7 | Breast Adenocarcinoma

United States, Canada, Peru, South Africa
NCIC Clinical Trials Group
National Cancer Institute (NCI); Southwest Oncology Group; North Central Cancer...

Completed

Bone Mineral Density in Postmenopausal Women With Primary Breast Cancer Who Are Receiving Treatment on Clinical Trial

Breast Cancer | Osteoporosis

Canada
NCIC Clinical Trials Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; Southwest... and other collaborators

Completed

Vinorelbine + Cisplatin or No Further Therapy in Non-small Cell Lung Cancer That Has Been Surgically Removed

Lung Cancer

United States, Canada
National Cancer Institute (NCI)
Canadian Cancer Trials Group

Active, not recruiting

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

United States, Canada, Israel, Puerto Rico
Ottawa Hospital Research Institute
Canadian Cancer Trials Group

Completed

Exercise in Men Receiving Radiation Therapy for Prostate Cancer.

Prostatic Neoplasms

Canada
Canadian Medical and Surgical Knowledge Translation...

Not yet recruiting

Pro-vascular Regenerative Cell Exhaustion in Women With Polycystic Ovarian Syndrome (PCOS-RCE)

Polycystic Ovary Syndrome

Canada
National Cancer Institute (NCI)
Canadian Cancer Trials Group

Active, not recruiting

Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer

Anal Canal Cloacogenic Carcinoma | Stage III Anal Cancer AJCC v8 | Anal Margin Squamous Cell Carcinoma | Stage IIB Anal Cancer AJCC v8 | Anal Basaloid Squamous Cell Carcinoma

United States, Canada
National Cancer Institute (NCI)
Canadian Cancer Trials Group

Active, not recruiting

Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy (PROSPER)

Metastatic Renal Cell Carcinoma | Sarcomatoid Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v7 | Unclassified Renal Cell Carcinoma | Stage II Renal Cell Cancer AJCC v7

United States, Canada, Israel
Canadian Myeloma Research Group
Merck Sharp & Dohme LLC

Withdrawn

A Study of Pembrolizumab Added to the Standard First-Line Therapy of Cyclophosphamide, Bortezomib, and Dexamethasone (CyBorD) for NDMM NTE

Multiple Myeloma

Canada
Canadian Cancer Trials Group
Merck Sharp & Dohme LLC

Terminated

Response to Pembrolizumab in Metastatic Melanoma: Computed Tomography Texture Analysis as a Predictive Biomarker

Metastatic Melanoma

Canada
University of British Columbia
Canadian Urologic Oncology Group

Completed

Lymph Node Processing Protocol for Radical Cystectomy and Pelvic Lymph Node Dissection in Bladder Cancer

Transitional Cell Carcinoma | Bladder Cancer

Canada
Oregon Health and Science University
Huntington Study Group; Huntington Society of Canada

Unknown

Ursodiol in Huntington's Disease (UDCA-HD)

Huntington Disease

United States
Gynecologic Oncology Group
National Cancer Institute (NCI); Canadian Cancer Trials Group

Completed

Radiation Therapy and Cisplatin With or Without Epoetin Alfa in Treating Patients With Cervical Cancer and Anemia

Anemia | Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Radiation Toxicity | Cervical Squamous Cell Carcinoma | Drug Toxicity | Stage IIB Cervical Cancer | Stage III Cervical Cancer | Stage IVA Cervical Cancer

United States
Canadian Cancer Trials Group
Canadian Cancer Clinical Trials Network; BC Cancer Foundation

Active, not recruiting

Prostate Cancer Biomarker Enrichment and Treatment Selection

Prostate Cancer

Canada
McMaster University
Canadian National Transplant Research Program; Canadian Critical Care Trials...

Completed

DONATE-Pilot Study on ICU Management of Deceased Organ Donors (DONATE-Pilot)

Critical Care | Deceased Organ Donors

Canada
National Cancer Institute (NCI)
Canadian Cancer Trials Group

Active, not recruiting

Atezolizumab in Treating Patients With Recurrent BCG-Unresponsive Non-muscle Invasive Bladder Cancer

Recurrent Bladder Urothelial Carcinoma | Stage 0a Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage 0is Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage I Bladder Urothelial Carcinoma AJCC v6 and v7

United States, Canada
National Cancer Institute (NCI)
Canadian Cancer Trials Group

Active, not recruiting

Testing Cabozantinib, Crizotinib, Savolitinib and Sunitinib in Kidney Cancer Which Has Progressed

Unresectable Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v7 | Stage IV Renal Cell Cancer AJCC v7 | Type 1 Papillary Renal Cell Carcinoma | Type 2 Papillary Renal Cell Carcinoma | Metastatic Papillary Renal Cell Carcinoma | Locally Advanced Papillary Renal Cell Carcinoma

United States, Canada
Canadian Cancer Trials Group
Ottawa Hospital Research Institute

Active, not recruiting

MG1 Maraba/MAGE-A3, With and Without Adenovirus Vaccine With Transgenic MAGE-A3 Insertion in Incurable MAGE-A3-Expressing Solid Tumours

Advanced/Metastatic Solid Tumours

Canada
University Health Network, Toronto
NCIC Clinical Trials Group; Princess Margaret Hospital, Canada

Completed

Celebrex - Cervix: Celecoxib in the Treatment of Patients With Locally Advanced Carcinoma of the Cervix

Cervix Neoplasms

Canada
Canadian Cancer Trials Group
Canadian Cancer Society (CCS); ATGen Canada Inc; Ontario Institute for Cancer... and other collaborators

Active, not recruiting

Immunization With IMM-101 vs Observation for Prevention of Respiratory and Severe COVID-19 Related Infections in Cancer Patients at Increased Risk of Exposure (COV-IMMUNO)

Covid-19 | Cancer

Canada
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI); Canadian Cancer Trials Group (CCTG)

Recruiting

Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer

Breast Screening

United States, Canada, Puerto Rico, Argentina, Korea, Republic of
NCIC Clinical Trials Group
National Cancer Institute (NCI); Medical Research Council; Eastern Cooperative... and other collaborators

Completed

Hormone Therapy With or Without Surgery or Radiation Therapy in Treating Patients With Prostate Cancer

Prostate Cancer

Canada
McMaster University
Canadian Institutes of Health Research (CIHR); Canadian Critical Care Trials...

Recruiting

REVIVe: Frailty, Rehabilitation, and Outcomes in Critically Ill Adult and Pediatric Survivors of COVID-19 or ARI (REVIVe)

COVID-19 | Respiratory Disease | Viral Infection

Canada
University Health Network, Toronto
Canadian Cancer Trials Group; Canadian Breast Cancer Research Alliance

Completed

RCT of a Group Intervention for Women With a Family History of Breast Cancer

Breast Neoplasms

Canada
Ontario Clinical Oncology Group (OCOG)
University Health Network, Toronto; Princess Margaret Hospital, Canada

Completed

A Pragmatic Trial of Ambulatory Toxicity Management in Patients Receiving Adjuvant or Neo-adjuvant Chemotherapy for Early Stage Breast Cancer (AToM)

Early Stage Breast Cancer

Canada
Canadian Medical and Surgical Knowledge Translation...
Amgen

Recruiting

A Study of Evolocumab on Carotid Artery Atherosclerotic Plaque Morphology Prior to Carotid EndArterectomy (SLICE-CEA)

Carotid Artery Stenosis | Asymptomatic Carotid Artery Stenosis

Canada
Ontario Clinical Oncology Group (OCOG)
Canadian Cancer Society (CCS)

Completed

Stereotactic Body Radiotherapy Versus Conventional Radiotherapy in Medically-Inoperable Non-Small Lung Cancer Patients (LUSTRE)

Non-small Cell Lung Cancer

Canada
OSI Pharmaceuticals
Canadian Cancer Trials Group

Completed

OSI-774 (Tarceva) in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

Carcinoma, Non-small-cell Lung

Canada, United States, Australia, Singapore, Israel, China, Argentina, Germany, Sweden, Brazil, Chile, Greece, Mexico, New Zealand, Romania, South Africa, Thailand
OSI Pharmaceuticals
Canadian Cancer Trials Group

Completed

OSI-774 (Tarceva) Plus Gemcitabine in Patients With Locally Advanced, Unresectable or Metastatic Pancreatic Cancer.

Pancreatic Cancer

United States, Canada, Australia, Israel, Singapore, United Kingdom, Germany, Belgium, Romania, Poland, Argentina, Brazil, Chile, Greece, Italy, Mexico, New Zealand
Ontario Clinical Oncology Group (OCOG)
Canadian Breast Cancer Initiative

Completed

Randomized Trial of Follow-up Strategies in Breast Cancer

Breast Cancer

Canada
Ontario Clinical Oncology Group (OCOG)
Canadian Cancer Society (CCS)

Completed

A Trial to Evaluate the Improvement in Lung Cancer Patients Receiving Radiation With or Without Brachytherapy (BRACHY)

Non-small Cell Lung Cancer

Canada
Novartis Pharmaceuticals
National Cancer Institute (NCI); Canadian Cancer Trials Group; North Central... and other collaborators

Completed

ALTTO (Adjuvant Lapatinib And/Or Trastuzumab Treatment Optimisation) Study; BIG 2-06/N063D (ALTTO)

Neoplasms, Breast

United States, Belgium, France, Spain, United Kingdom, Croatia, Estonia, India, Italy, Canada, Netherlands, Argentina, Australia, Austria, Czechia, Denmark, Germany, Israel, Japan, Norway, Poland, Russian Federation, Switzerland, Taiwan, Korea, Republic... and more
Ontario Clinical Oncology Group (OCOG)
Canadian Breast Cancer Foundation

Completed

Trial of Radiation Fractionation Schedules for Once-a-Day Accelerated Partial Breast Irradiation (OPAR)

Breast Cancer | DCIS

Canada
Canadian Cancer Trials Group
University Health Network, Toronto; AstraZeneca

Active, not recruiting

CFI-400945 and Durvalumab in Patients With Advanced Triple Negative Breast Cancer

Breast Cancer

Canada
CHU de Quebec-Universite Laval
Canadian Institutes of Health Research (CIHR); Canadian Critical Care Trials... and other collaborators

Completed

HEMOglobin Transfusion Threshold in Traumatic Brain Injury OptimizatioN: The HEMOTION Trial (HEMOTION)

Traumatic Brain Injury | Transfusion

Canada, United Kingdom, Brazil, France
Vastra Gotaland Region
Australasian Leukaemia and Lymphoma Group; The Canadian Blood and Marrow Transplant...

Completed

Reduced Intensity Conditioning Transplantation Versus Standard of Care in Acute Myeloid Leukemia

Acute Myeloid Leukemia

Finland, Australia, Canada, New Zealand, Sweden, Estonia, Germany, Greece, Norway
Canadian Cancer Trials Group
Celgene; Australian and New Zealand Urogenital and Prostate Cancer Trials Group

Completed

Nab-Paclitaxel to Paclitaxel in Advanced Urothelial Cancer Progressing on or After Platinum Containing Regimen.

Urothelial Cancer

Canada, Australia
Mount Sinai Hospital, Canada
Canadian Institutes of Health Research (CIHR); University of Toronto; The Art... and other collaborators

Completed

Meditation Versus Education for Improving Depression in Chronic Pain, a Randomized Controlled Trial

Depression | Chronic Pain

Canada
Canadian Cancer Trials Group
Melanoma and Skin Cancer Trials Limited

Recruiting

Duration of Anti-PD-1 Therapy in Metastatic Melanoma (STOP-GAP)

Unresectable/Metastatic Melanoma

Canada, Australia
National Cancer Institute (NCI)
NRG Oncology; Canadian Cancer Trials Group

Active, not recruiting

Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer

Endometrial Clear Cell Adenocarcinoma | Endometrial Dedifferentiated Carcinoma | Endometrial Endometrioid Adenocarcinoma | Endometrial Mixed Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Undifferentiated Carcinoma | Recurrent Endometrial Adenocarcinoma | Recurrent Endometrial... and other conditions

United States, Korea, Republic of, Canada, Puerto Rico, Japan
Maisonneuve-Rosemont Hospital
The Canadian Blood and Marrow Transplant Group

Terminated

Steroids, Azithromycin, Montelukast, and Symbicort (SAMS) for Viral Respiratory Tract Infection Post Allotransplant

Respiratory Tract Infections | Lung Diseases, Interstitial | Bronchiolitis Obliterans | Cryptogenic Organizing Pneumonia

Canada
University of Calgary
The Canadian Blood and Marrow Transplant Group

Completed

Use of Haploidentical Related Donors for Patients Without Matched Sibling, Unrelated Donor or Cord Blood Units

Hematologic Neoplasms

Canada
Laval University
National Cancer Institute (NCI); Canadian Cancer Trials Group

Completed

Beta-carotene and Alpha-tocopherol Chemoprevention of Second Primary Malignancies in Head and Neck Cancer Patients

Neoplasms

Canada
Ontario Clinical Oncology Group (OCOG)
Canadian Breast Cancer Research Alliance

Completed

Accelerated Radiotherapy Outcomes in Women

Breast Cancer

Canada
Ontario Clinical Oncology Group (OCOG)
Canadian Breast Cancer Research Alliance

Completed

Trial of Decongestive Lymphatic Therapy for Lymphedema in Women With Breast Cancer "DELTA STUDY"

Breast Cancer | Lymphedema

Canada
Lawson Health Research Institute
QLT Inc.; Canadian Retinal Trials Group

Completed

Combination Therapy for Age-Related Macular Degeneration.

Age Related Macular Degeneration

Canada
Canadian Cancer Trials Group
Merck Sharp & Dohme LLC; Seagen Inc.

Recruiting

Pembrolizumab and Brentuximab Vedotin vs GDP and Stem Cell Transplant for Relapsed/Refractory Hodgkin Lymphoma

Hodgkin Lymphoma

Canada
Canadian Cancer Trials Group
AbbVie; Roche Pharma AG; Incyte Corporation

Recruiting

Phase I Master Protocol of Novel Combination Therapy for Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma

Lymphoma, B-Cell

Canada
National Cancer Institute (NCI)
NRG Oncology; Canadian Cancer Trials Group

Active, not recruiting

Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage... and other conditions

United States, Canada

Clinical Trials Sponsored by Sorin Group Canada

Sponsors and Collaborators

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CROs in Malaysia

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