Search clinical trials for: Anti-PDL1

Total 97529 results

AiCuris Anti-infective Cures AG

Completed

Thorough QT/QTc of Pritelivir in Healthy Subjects

HSV Infection

United Kingdom
University Hospital, Basel, Switzerland

Completed

Inhibition of Food Intake in Response to Oral GLP-1 and Peptide YY3-36

Anti Obesity Agent

Switzerland
University of Turin, Italy

Recruiting

UNITO-001- Study in HRR/PDL1 Positive MPM/NSCLC (UNITO-001)

Lung Cancer | Mesothelioma

Italy
Radboud University Medical Center
Leiden University Medical Center

Not yet recruiting

Multimodal Imaging in Rectal Cancer & Pancreatic Cancer (MIRCA & MIPAC)

Pancreatic Cancer | Rectal Cancer

Netherlands
iOMEDICO AG
Merck Sharp & Dohme LLC; Arbeitsgemeinschaft fur Internistische Onkologie; Arbeitskreis... and other collaborators

Completed

Epidemiological EMESIS-Registry (EMESIS)

Antiemetic Therapy

Germany
Merck Sharp & Dohme LLC

Recruiting

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Solid Tumors | Hematologic Malignancies

United States, Poland, Brazil, Ukraine, Argentina, Australia, Austria, Belgium, Canada, Chile, China, Colombia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Guatemala, Hong Kong, Hungary, Israel, Italy, Japan, Korea, Republic... and more
Merck Sharp & Dohme LLC

Completed

Study of Pemetrexed + Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With Tyrosine Kinase Inhibitor- (TKI)-Resistant Epidermal Growth Factor Receptor- (EGFR)-Mutated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-789/KEYNOTE-789)

Non-small Cell Lung Cancer

China, Taiwan, Japan, Korea, Republic of, United States, Australia, Brazil, Canada, France, Germany, Hong Kong, Israel, Italy, Mexico, Spain, Sweden, United Kingdom
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)

Breast Cancer

Japan, Poland, United States, Australia, Belgium, Brazil, Canada, China, Colombia, Costa Rica, France, Germany, Hungary, Ireland, Israel, Korea, Republic of, New Zealand, Portugal, Puerto Rico, Russian Federation, Spain, Taiwan, Ukr... and more
Merck Sharp & Dohme LLC

Completed

Study of Pembrolizumab (MK-3475) Versus Platinum-Based Chemotherapy for Participants With Programmed Cell Death-Ligand 1 (PD-L1)-Positive Advanced or Metastatic Non-Small Cell Lung Cancer (MK-3475-042/KEYNOTE-042)

Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC

Completed

A Study of Carboplatin-Paclitaxel/Nab-Paclitaxel Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With First Line Metastatic Squamous Non-small Cell Lung Cancer (MK-3475-407/KEYNOTE-407)

Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC

Terminated

Study of Lenalidomide and Dexamethasone With or Without Pembrolizumab (MK-3475) in Participants With Newly Diagnosed Treatment Naive Multiple Myeloma (MK-3475-185/KEYNOTE-185)

Multiple Myeloma
Merck Sharp & Dohme LLC

Completed

Study of Pembrolizumab (MK-3475) in Participants With Advanced Non-small Cell Lung Cancer (MK-3475-025/KEYNOTE-025)

Non-small Cell Lung Cancer
Nourhan M.Aly
Alexandria University

Completed

Sublingual Versus Intranasal Administration of Dexmedetomidine for Sedation of Children Undergoing Dental Treatment

Moderate Sedation | Anti-anxiety Agents

Egypt
Children's Mercy Hospital Kansas City
Patient-Centered Outcomes Research Institute; Washington University School... and other collaborators

Completed

Resetting the Default: Improving Provider-patient Communication to Reduce Antibiotic Misuse

Communication | Personal Satisfaction | Decision Making | Anti-Bacterial Agents

United States
Eli Lilly and Company

Active, not recruiting

A Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumors (PACT)

Pancreatic Cancer | Solid Tumor | Cutaneous Melanoma | Microsatellite Instability-High (MSI-H) Solid Tumors | Breast Cancer (HR+HER2-)

Belgium, Spain, Korea, Republic of, United States, Taiwan, France, Canada
Shanghai Jiao Tong University School of Medicine

Recruiting

Neoadjuvant Personalized Anti-PD-1 and Anti-VEGFR Therapy in OSCC Patients

Oral Squamous Cell Carcinoma | Anti-PD-1 | Neoadjvant Therapy | Anti-VEGFR

China
Noah Merin
Johns Hopkins University

Terminated

Convalescent Plasma in ICU Patients With COVID-19-induced Respiratory Failure

Covid-19 | Sars-CoV2

United States
Merck KGaA, Darmstadt, Germany

Completed

Multiple Ascending Dose Trial of MSB0010841 (Anti-IL17A/F Nanobody) in Psoriasis Subjects

Psoriasis

Germany
Nanjing University School of Medicine

Completed

MMF Versus CTX in the Induction Treatment of ANCA Associated Vasculitis

Vasculitis | Anti-Neutrophil Cytoplasmic Antibody

China
Hoffmann-La Roche

Completed

A Study of Atezolizumab Compared With Chemotherapy in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer [IMvigor211]

Bladder Cancer

United States, France, Belgium, Korea, Republic of, United Kingdom, Czechia, Austria, Canada, Denmark, Greece, Italy, Netherlands, Portugal, Slovenia, Spain, Sweden, Turkey, Poland, Hungary, Switzerland, Japan, Taiwan, Australia, Norway, Germa... and more
University of North Carolina, Greensboro

Recruiting

The Optimization and Evaluation of the Extremism and Intolerance Curriculum for the Kingdom of Bahrain.

Tolerance | Empathy | Literacy | Norm, Social | Resistance Skills | Beliefs About Consequences | Decision Making Skills | Open Mindedness | Active Citizenship | Anti-extremism

United States
Jiangsu Province Centers for Disease Control and...

Completed

Study on Dynamic Changes of the Maternal Anti-EV71 and Anti-CVA16 Antibody Levels in Infants and Young Children

Hand, Foot and Mouth Disease | Anti-EV71 | Anti-CVA16

China
National Cancer Institute (NCI)

Completed

Anti-CD19 White Blood Cells for Children and Young Adults With B Cell Leukemia or Lymphoma

Leukemia | B Cell Lymphoma | Non-Hodgkin Lymphoma | ALL | Large Cell Lymphoma

United States
UCB Pharma

Completed

Facial Thermography Study of Levocetirizine Versus Cetirizine

Anti-allergic Agents
Sandoz

Completed

Clinical Study for Comparative Assessment of Efficacy and Safety of Angal S, Topical Spray and ANTI-ANGIN® FORMULA, Topical Metered Spray in Treatment of Patients With Uncomplicated Acute Infectious and Inflammatory Diseases of the Pharynx, Accompanied by a Sore Throat

Sore Throat

Russian Federation
National Eye Institute (NEI)
The Emmes Company, LLC

Completed

Human Anti-Tac (Daclizumab) to Treat Juvenile Idiopathic Arthritis (JIA)-Associated Uveitis

Immunosuppression | Anterior Uveitis | Arthritis, Juvenile Idiopathic | Iritis

United States
Vitreous -Retina- Macula Consultants of New York

Completed

To Evaluate The Role of Intravitreal Aflibercept Injection (2.0 mg) in the Management of Previously Treated Patients With Exudative AMD

AMD (With Persistent or Recurrent Fluid Despite Monthly Intravitreal Anti-VEGF Therapy)

United States
University of Roma La Sapienza

Completed

REpetitive Assessement of SCOREs in Patients on Dual Antiplatelet Therapy (RE-SCORE)

Dual Anti-platelet Therapy

Italy
Deraya University

Completed

Studying of Natural Constituents' Treatment of Plantar Warts

Plantar Wart

Egypt
Kurume University

Unknown

Metabolic and Cardiovascular Effects of Dipeptidyl Peptidase-4 (DPP-4) or Sodium-glucose Co-transporter Type 2 (SGLT2) Inhibitors

Effects of the DPP-4 Inhibitors or SGLT2 Inhibitors on the Protective Actions for Diabetic Complications

Japan
Altitude Physiology Expeditions
University of Edinburgh

Completed

Anti-Oxidant Supplementation for the Prevention of Acute Mountain Sickness

Acute Mountain Sickness

United Kingdom
National Center for AIDS/STD Control and Prevention...
BMS company

Completed

Unboosted Atazanavir as Initial ART Therapy in China

Antiretroviral Therapy

China
Centre Leon Berard
AstraZeneca; Plexxikon

Completed

Evaluation of Safety and Activity of an Anti-PDL1 Antibody (DURVALUMAB) Combined With CSF-1R TKI (PEXIDARTINIB) in Patients With Metastatic/Advanced Pancreatic or Colorectal Cancers (MEDIPLEX)

Colorectal Cancer | Pancreatic Cancer | Metastatic Cancer | Advanced Cancer

France
CerbaXpert

Not yet recruiting

Study of the Transmission of Anti-interferon Type 1 Alpha Autoantibodies From Mother to Child Via the Placental Barrier (Pregiferon)

Woman Suffering From a Pathology Frequently Associated With the Presence of These Anti-autoantibodies Type-I Interferons
CONRAD
University of Washington; Centers for Disease Control and Prevention; Kenya Medical...

Unknown

Tenofovir/Levonorgestrel Intravaginal Ring and Tenofovir Intravaginal Ring

HIV | Contraception | Prevention | Anti-Retroviral Agent

Kenya
Hospices Civils de Lyon

Recruiting

Immunoglobulin M (IgM)-Anti-myelin-associated-glycoprotein(MAG) Peripheral Neuropathy Study

Immunoglobin M Anti-myelin-associated-glycoprotein Peripheral Neuropathy

France
Assiut University

Unknown

Diagnostic Value of Anti-MCV in Pts With RA

Anti-MCV in Rheamatoid Arthritis
St George's, University of London
London School of Hygiene and Tropical Medicine; University of Botswana

Completed

A Randomised Trial to Evaluate Toxicity and Efficacy of 1200mg and 1800mg Rifampicin for Pulmonary Tuberculosis (RIFASHORT)

Pulmonary Tuberculosis

Botswana, Guinea, Nepal, Pakistan, Peru, Uganda
Assiut University

Not yet recruiting

Vitamin D With Omega-3 or Metformin in Osteoarthritis

Osteoarthritis
Shanghai Changzheng Hospital

Unknown

Arsenic Trioxide for Structural p53 Mutations

Refractory Cancer | Arsenic Trioxide | p53 Mutations | Intractable Cancer

China
Alliancells-PuRui Biocience Co., Ltd.
Zhongyuan Union Stem Cell Bio-engineering Corporation

Unknown

Safety Study of Cord Blood-derived Cytokine-induced Killer Cells in Patients With Solid Tumor After Radical Resection

Renal Cell Carcinoma | Hepatocellular Carcinoma | Lung Cancer

China
Henan Cancer Hospital

Not yet recruiting

Clinical Study of Trop2 CAR-NK in the Treatment of Relapsed/Refractory Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer NSCLC
Thrasher Research Fund
Centers for Disease Control and Prevention

Completed

Use of OraQuick for Screening HIV in Children Less Than Eighteen Months Old

HIV Antibody Testing

Zambia
University of Zurich
Incyte Corporation

Not yet recruiting

Topical Ruxolitinib Evaluation in Immune-related Lichenoid Skin-Toxicities (TRUX-LST)

Exanthema | Lichenoid Skin Rashes Under Anti-PD1 Tumor Therapy
Central Hospital, Nancy, France
University Hospital, Strasbourg, France; CHU de Reims; Centre Hospitalier Universitaire... and other collaborators

Recruiting

Association Between Cancer and Anti-synthetase Syndrome

Antisynthetase Syndrome

France
University Medical Center Groningen
Fresenius Medical Care North America

Completed

Immunoadsorption in Anti-GBM Glomerulonephritis.

Anti-glomerular Basement Membrane Glomerulonephritis

Netherlands
Merck Sharp & Dohme LLC

Terminated

Study of Pomalidomide and Low Dose Dexamethasone With or Without Pembrolizumab (MK-3475) in Refractory or Relapsed and Refractory Multiple Myeloma (rrMM) (MK-3475-183/KEYNOTE-183)

Multiple Myeloma
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy Study of Pembrolizumab (MK-3475) in Chinese Participants With Locally Advanced or Metastatic Melanoma (MK-3475-151/KEYNOTE-151)

Melanoma
Merck Sharp & Dohme LLC

Active, not recruiting

Study of MK-4830 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-4830-001)

Neoplasms

Poland, United States, Australia, Canada, China, France, Greece, Israel, Japan, Korea, Republic of, South Africa, Spain
Merck Sharp & Dohme LLC

Completed

Study of Favezelimab (MK-4280) as Monotherapy and in Combination With Pembrolizumab (MK-3475) With or Without Chemotherapy or Lenvatinib (MK-7902) AND Favezelimab/Pembrolizumab (MK-4280A) as Monotherapy in Adults With Advanced Solid Tumors (MK-4280-001)

Neoplasms

Search clinical trials for: Anti-PDL1

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