Search clinical trials for: Cholangiocarcinoma Metastatic with an IDH-1 Mutation

Total 484566 results

Sunnybrook Health Sciences Centre

Recruiting

UNITy-BasED MR-Linac Adaptive Simultaneous Integrated Hypofractionated Boost Trial for High Grade Glioma in the Elderly (UNITED2)

Glioblastoma, IDH-mutant | Glioblastoma Multiforme, Adult

Canada
Haruhiko Fukuda
Ministry of Health, Labour and Welfare, Japan

Completed

Trial to Evaluate Radiotherapy Followed by Endocrine Therapy Vs Endocrine Therapy Alone for PSA Failure After Radical Prostatectomy

Prostate Cancer

Japan
Gazi University
Hacettepe University; Cukurova University; Marmara University; Istanbul University and other collaborators

Unknown

Evaluation of Status of Early Reached Target Enteral Nutrition and IFABP as Biomarker of Feeding Intolerance in Critically Ill Children (ERTENIFABPICU)

Enteral Nutrition | Feeding Intolerance | Intestinal Fatty Acid Binding Protein

Germany
Ningbo No. 1 Hospital

Recruiting

Association Between Cardiovascular Diseases and Mental Illness

Cardiovascular Diseases | Mental Disorder

China
Ningbo No. 1 Hospital

Completed

Development and Validation for Predicting Inadequate Bowel Preparation

Colonoscopy | Polyethylene Glycol | Cathartics

China
University of Oran 1

Completed

Factors Influencing Occurrence Of Hilar Biliary Stricture In Case of Bile Duct Injury

Bile Duct Injury

Algeria
Ningbo No. 1 Hospital

Completed

UEMR vs. CEMR for Diminutive Non-pedunculated Colorectal Polyps

Colonic Polyps

China
Ningbo No. 1 Hospital

Completed

Comparison of Using Regular or Rotary Polypectomy Snare for the Resection of Colorectal Polyps

Polypectomy Snare

China
University of Yaounde 1

Completed

A Trial of the Efficacy of Artesunate and Three Quinine Regimens in the Treatment of Severe Malaria in Children at the Ebolowa Regional Hospital - Cameroon

Malaria
University of Melbourne
Merck Sharp & Dohme LLC; The Alfred

Terminated

Combination Latency Reversal With High Dose Disulfiram Plus Vorinostat in HIV-infected Individuals on ART

HIV Infections

Australia
Institut de Recherches Internationales Servier

Recruiting

Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

Myelodysplastic Syndromes | Relapsed or Refractory Acute Myeloid Leukemia (AML) | Untreated AML | Other IDH1-mutated Positive Hematologic Malignancies

United States, France
Eli Lilly and Company

Active, not recruiting

A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Relapsed Solid Tumor | Refractory Solid Tumor

United States, France, Australia, Belgium, Germany, Japan, Spain, Italy
Eli Lilly and Company
Incyte Corporation

Active, not recruiting

A Study of Baricitinib (LY3009104) in Participants With Severe or Very Severe Alopecia Areata (BRAVE-AA1)

Alopecia Areata

United States, Japan, Puerto Rico, Mexico, Korea, Republic of
Eli Lilly and Company

Terminated

A Study of LY3844583 in Healthy Participants and Participants With Atopic Dermatitis

Healthy | Dermatitis, Atopic

Japan, United States
Eli Lilly and Company

Active, not recruiting

A Study to Evaluate Tirzepatide (LY3298176) in Pediatric and Adolescent Participants With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin or Basal Insulin or Both (SURPASS-PEDS)

Glucose Metabolism Disorders | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Endocrine System Diseases | Type2 Diabetes | Metabolic Disease | T2DM (Type 2 Diabetes Mellitus) | T2D

United States, India, Australia, United Kingdom, Mexico, Brazil, Israel, France, Italy
Eli Lilly and Company

Active, not recruiting

A Study of LY3437943 in Healthy Participants With a High Body Mass Index

Healthy

United States
Eli Lilly and Company

Active, not recruiting

A Study of Ixekizumab (LY2439821) in Children With Juvenile Idiopathic Arthritis Categories of Enthesitis-related Arthritis (Including Juvenile Onset Ankylosing Spondylitis) and Juvenile Psoriatic Arthritis

Juvenile Psoriatic Arthritis | Enthesitis Related Arthritis

Spain, Belgium, Germany, Italy, United Kingdom, Denmark, Mexico, Netherlands, Switzerland
Eli Lilly and Company

Completed

A Study of Insulin Efsitora Alfa (LY3209590) as a Weekly Basal Insulin Compared to Insulin Glargine in Adult Participants With Type 2 Diabetes on Multiple Daily Injections (QWINT-4)

Type 2 Diabetes | Type 2 Diabetes Treated With Insulin

United States, Germany, Mexico, Argentina, Puerto Rico, Italy, Spain, India
Eli Lilly and Company

Completed

A IMMA Master Protocol: A Study of LY3361237 in Participants With at Least Moderately Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States, Puerto Rico, Czechia, Taiwan, Argentina, France, Poland, Mexico
Eli Lilly and Company

Completed

A Study of LY3457263 Alone and in Combination With Dulaglutide (LY2189265) in Participants With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States
Eli Lilly and Company

Active, not recruiting

A Study of LY3484356 in Chinese Participants With Advanced Breast Cancer

Breast Neoplasms

China
Eli Lilly and Company

Completed

A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Diabetic Peripheral Neuropathic Pain (NP05)

Chronic Pain | Diabetic Peripheral Neuropathic Pain | Diabetic Peripheral Neuropathy

United States, Puerto Rico
AHS Cancer Control Alberta
Tom Baker Cancer Centre

Recruiting

Study of Niacin in Glioblastoma

Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype

Canada
Pfizer

Terminated

A Phase 2B Multicenter, Randomized, Comparative Trial Of UK-453,061 Versus Etravirine In Combination With Darunavir/Ritonavir And A Nucleos(t)Ide Reverse Transcriptase Inhibitor For The Treatment Of Antiretroviral Experienced HIV-1 Infected Subjects With Evidence Of NNRTI Resistant HIV-1

HIV-1

Spain, United Kingdom, Malaysia, United States, Portugal, Brazil, Germany, Italy, Poland, Puerto Rico, South Africa, Taiwan, Ukraine
ViiV Healthcare
Pfizer

Terminated

Comparative Trial Of Maraviroc Versus Emtricitabine/Tenofovir Both With Darunavir/Ritonavir In Antiretroviral-Naive Patients Infected With CCR5 Tropic HIV 1 (MODERN)

HIV-1

United States, Netherlands, Spain, Puerto Rico, Canada, Australia, Germany, Sweden, Poland, Portugal, Switzerland, France, Denmark, Italy, Belgium, United Kingdom, Hungary, Austria, Finland
Tibotec Pharmaceuticals, Ireland

Completed

The TMC125-C214 Study Provides Early Access to TMC125 for HIV-1 Infected Patients Who Have Failed Multiple Antiretroviral Regimens and Will Also Gather Information on the Long-term Safety and Tolerability of TMC125 Combined With Other Antiretroviral Drugs

HIV-1

United States, Belgium, Germany, Taiwan, Spain, Mexico, Turkey, Canada, Netherlands, Denmark, Greece, Sweden, Korea, Republic of, Russian Federation, Puerto Rico, Luxembourg
Juan A. Arnaiz

Completed

Metabolic Effects of Atazanavir/Ritonavir Versus Darunavir/Ritonavir in Combination With Tenofovir/Emtricitabine in naïve HIV-1 Infected Patients

HIV-1

Spain
GlaxoSmithKline

Terminated

Open Label Study of 908/RTV in Combination With Other PIs for the Treatment of Multi PI-Experienced HIV Subjects

HIV-1

Australia, Belgium, Canada, France, Germany, Greece, Italy, Spain, United Kingdom
University of Parma

Unknown

Integrated Strategies to Prevent Intradialytic Hypotension (The DialHypot Study) (DialHypot)

Hypotension During Dialysis | Dialysis Hypotension

Italy
B.P. Koirala Institute of Health Sciences

Unknown

A Comparative Study of Airtraq Versus Macintosh Laryngoscope for Endotracheal Intubation by First Year Resident

Intubation Complication | Intubation; Difficult or Failed

Nepal
Ono Pharmaceutical Co. Ltd

Completed

A Study of FOY-305 in Patients With SARS-Cov-2 Infection (COVID-19)

SARS-CoV-2 Infection (COVID-19)

Japan
Haruhiko Fukuda
Ministry of Health, Labour and Welfare, Japan

Completed

Trial of TP Versus TC Regimens for Stage IVb, Persistent, or Recurrent Cervical Cancer (JCOG0505, CC-TPTC-P3)

Uterine Cervical Neoplasms

Japan
Eli Lilly and Company

Recruiting

A Drug-Drug Interaction (DDI) Study of Orforglipron With Carbamazepine in Healthy Participants

Healthy

United States
Eli Lilly and Company

Recruiting

A Study of LY3938577 in Healthy Participants and Participants With Type 1 Diabetes Mellitus (T1DM)

Healthy | Type 1 Diabetes Mellitus

Germany
Eli Lilly and Company

Completed

A Study of LY3461767 in Participants With Chronic Heart Failure With Reduced Ejection Fraction

Chronic Heart Failure With Reduced Ejection Fraction

United States, Japan
Eli Lilly and Company

Active, not recruiting

A Study of (LY3650150) Lebrikizumab to Assess the Safety and Efficacy of Adult and Adolescent Participants With Moderate-to-Severe Atopic Dermatitis and Skin of Color (ADmirable)

Atopic Dermatitis

United States
Eli Lilly and Company

Completed

A Study of Imlunestrant (LY3484356) in Female Participants With Impaired Liver Function

Hepatic Insufficiency | Healthy

United States
Eli Lilly and Company

Completed

A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Chronic Low Back Pain

Chronic Low-back Pain

United States, Puerto Rico
Merck Sharp & Dohme LLC

Completed

Study of Pembrolizumab (MK-3475) Plus Docetaxel Versus Placebo Plus Docetaxel in Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-921/KEYNOTE-921)

Prostatic Neoplasms

United States, Argentina, Australia, Austria, Brazil, Canada, Chile, China, Colombia, France, Germany, Ireland, Israel, Italy, Japan, Korea, Republic of, Netherlands, Russian Federation, Spain, Taiwan, United Kingdom
Pfizer
Medivation, Inc.; Myriad Genetic Laboratories, Inc.

Terminated

A Phase 2, 2-Stage, 2-Cohort Study of Talazoparib (BMN 673), in Locally Advanced and/or Metastatic Breast Cancer Patients With BRCA Mutation (ABRAZO Study) (ABRAZO)

Breast Neoplasms | BRCA 1 Gene Mutation | BRCA 2 Gene Mutation

United States, Spain, United Kingdom, Germany, France
Haruhiko Fukuda
Ministry of Health, Labour and Welfare, Japan

Completed

A Phase II Study of Stereotactic Body Radiation Therapy in Patients With T1N0M0 Non-small Cell Lung Cancer (JCOG0403)

T1N0M0 Non-small Cell Lung Cancer

Japan
Abbott Diabetes Care

Recruiting

Effect on HbA1c of the Initiation of CGM in Adults With Type 2 Diabetes Treated With Basal Insulin in Finland

Type 2 Diabetes Treated With Insulin

Finland
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of LY3410738 in Healthy Adult Participants

Healthy

United States
Eli Lilly and Company

Completed

Phase 2 Study of Gemcitabine or Gemcitabine + Enzastaurin in Participants With Advanced or Metastatic Pancreatic Cancer

Pancreatic Neoplasm

United States
photonamic GmbH & Co. KG

Recruiting

PD L 506 for Stereotactic Interstitial Photodynamic Therapy of Newly Diagnosed Supratentorial IDH Wild-type Glioblastoma

Glioblastoma

Germany
National Cancer Institute (NCI)
NRG Oncology

Recruiting

Testing the Addition of the Immune Therapy Drugs, Tocilizumab and Atezolizumab, to Radiation Therapy for Recurrent Glioblastoma

Recurrent Glioblastoma | Diffuse Astrocytoma, IDH-Wildtype

United States
Haruhiko Fukuda
Ministry of Health, Labour and Welfare, Japan

Completed

Rituximab+Standard CHOP vs Rituximab+Bi-weekly CHOP for Untreated Stage III/IV Low-grade B-cell Lymphoma (JCOG0203)

Lymphoma, B-Cell

Japan
Ningbo No. 1 Hospital

Recruiting

Cold Snare Polypectomy Versus Hot Snare Polypectomy for Resection of Small Pedunculated Colorectal Polyps：a Randomized Controlled Trial

Haemorrhage | Pedunculated Colorectal Polyps

China
Ningbo No. 1 Hospital

Not yet recruiting

Position Changes in Cirrhosis Hemorrhagic Spot Detection

Emergency Hemostasis

China
Ningbo No. 1 Hospital

Recruiting

A New Ligation Using the Double-loop Clips Technique Versus Traditional Techniques in the Treatment of Large Wounds After Endoscopic Resection

Polyps | Closure; Delay

China

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