Search clinical trials for: Cognitive Aging

Total 16614 results

Columbia University
National Institute on Aging (NIA)

Recruiting

Discovery and Validation of Genetic Variants Affecting Microglial Activation in Alzheimer's Disease

Alzheimer Disease

United States
Bryan Denny
National Institute on Aging (NIA)

Recruiting

Neural Mechanisms of Enhancing Emotion Regulation in Bereaved Spouses

Depressive Symptoms | Emotions | Grief | Bereavement | Affect

United States
University of Michigan
National Institute on Aging (NIA)

Recruiting

Stimulation of Cingulo-opercular Alertness Network (SCAN)

Lewy Body Dementia With Behavioral Disturbance | Lewy Body Disease | Lewy Body Variant of Alzheimer Disease

United States
Neurobehavioral Systems, Inc.
National Institutes of Health (NIH)

Recruiting

Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease

Alzheimer Disease | Aging | Cognitive Decline

United States
Tulane University
National Institute on Aging (NIA); Wake Forest University

Recruiting

Implementation of Multifaceted Patient-Centered Treatment Strategies for Intensive Blood Pressure Control in Minimize Cognitive Decline (IMPACTS-MIND)

Hypertension | Cognitive Decline

United States
Benjamin Rose Institute on Aging

Recruiting

LifeBio Memory Digital Reminiscence Platform

Cognitive Impairment | Dementia

United States
Vanderbilt University Medical Center

Recruiting

Cholinergic Mechanisms of Attention in Aging

Subjective Cognitive Decline

United States
Vanderbilt University Medical Center
National Institute on Aging (NIA)

Recruiting

Early Cognitive Intervention in Delirium (ECID)

Delirium | Dementia | Cognitive Decline

United States
Bright Cloud International Corp
National Institute on Aging (NIA); Rutgers, The State University of New Jersey

Recruiting

Telerehabilitation Alzheimer's Disease Feasibility (TADF) (TADF)

Alzheimer Disease | Healthy Aging

United States
Chang Gung Memorial Hospital

Recruiting

The Effectiveness of Lifestyle Redesign Training in Elderly With Cognitive Decline

Aging

Taiwan
University of Miami
Columbia University; National Institute on Aging (NIA); Case Western Reserve... and other collaborators

Recruiting

Genetic Studies in Familial Dementia

Dementia | Mild Cognitive Impairment | Alzheimer Disease, Early Onset | Alzheimer Disease, Late Onset | Dementia of Alzheimer Type

United States
Louis Bherer

Recruiting

The Cognitive and spOrt Virtual EPIC Training Study (COVEPIC)

Aging

Canada
Tammie L. S. Benzinger, MD, PhD

Recruiting

Neuroimaging in Healthy Aging and Senile Dementia (HASD_IND) (HASD_PIB_IND)

Alzheimer Disease

United States
National Cheng Kung University
Ministry of Science and Technology, Taiwan

Recruiting

Brain-Health Lifestyle Restructuring Intervention

Aging | Cognitive Decline | Lifestyle

Taiwan
Patrick Lao
National Institute on Aging (NIA)

Recruiting

Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease (ADVISe)

Alzheimer Disease

United States
University of California, Los Angeles
National Institute on Aging (NIA)

Recruiting

Network-targeted Theta-burst Stimulation for Episodic Memory Improvement in Mild Cognitive Impairment

Cognitive Dysfunction | Memory Disorders in Old Age

United States
Duke University
National Institute on Aging (NIA)

Recruiting

Network-guided TMS in Early Alzheimer's Disease (NetTMS)

Mild Cognitive Impairment

United States
University of Rochester
National Institute of Nursing Research (NINR); Stanford University

Recruiting

Breathing, Relaxation, Attention Training, & Health in Older Adults (BREATHE)

Healthy Aging | Mild Cognitive Impairment

United States
The Opole University of Technology

Recruiting

Prevalence, Determinants and Natural History of Frailty and Pre-frailty in Elderly People (FRAILPOL)

Frail Elderly Syndrome | Frailty | Aging | Frailty Syndrome | Aging Problems | Fragility | Aging Well | Aging Disorder

Poland
Butler Hospital
Brown University; The Miriam Hospital; Alzheimer's Association

Recruiting

Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD (LINE-AD)

Mild Cognitive Impairment | Alzheimer Disease, Early Onset | Moderate Dementia

United States
Beijing Tiantan Hospital
Beijing Stroke Association

Recruiting

Ginkgo Leaf Extract and Armillariella Mellea Powder Oral Solution for the Treatment of Motoric Cognitive Risk Syndrome

Aging | Mild Cognitive Impairment | Motoric Cognitive Risk Syndrome | Locomotive Syndrome

China
Eisai Inc.
National Institute on Aging (NIA); Biogen; Alzheimer's Clinical Trials Consortium

Recruiting

AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With Lecanemab in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid

Preclinical Alzheimer's Disease | Early Preclinical Alzheimer's Disease

United States, Singapore, Canada, Spain, Australia, Japan, United Kingdom, Sweden, Netherlands
University of Washington
National Institute on Aging (NIA); Ellison Foundation

Not yet recruiting

University of Washington Alzheimer's Disease Research Center (UW ADRC) Imaging & Biomarker Core

Alzheimer Disease
Mclean Hospital
National Institute on Aging (NIA)

Recruiting

Effects of Nicotinamide Riboside on Bioenergetics and Oxidative Stress in Mild Cognitive Impairment/Alzheimer's Dementia

Mild Cognitive Impairment | Mild Alzheimer Disease

United States
National Institute on Aging (NIA)

Recruiting

Ketone Ester Effects on Biomarkers of Brain Metabolism and Cognitive Performance in Cognitively Intact Adults 55 Years Old or Older

Metabolic Syndrome | Normal Cognition

United States
University of Calgary
The Brenda Strafford Foundation

Not yet recruiting

Sleep Quality in Assisted-Living Residents

Sleep Disturbance | Aging
University Hospital, Caen

Recruiting

Anxiety/Depression, Sleep and Alcohol in Elderly Anxiety/Depression, Sleep Disturbances and Alcohol Use Disorder in Elderly With Cognitive Complaints (MEM-ASA)

Dementia | Sleep Disturbance | Aging | Anxiety State | Alcohol Abuse

France
Rush University Medical Center
University of Chicago; National Institute on Aging (NIA); Advocate Hospital System

Recruiting

Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in Stroke Patients Patients

Stroke | Dementia | Alzheimer Disease | Dementia, Vascular | Cognitive Decline

United States
University of Illinois at Urbana-Champaign
Wayne State University

Recruiting

Yoga, Aerobic and Stretching Exercise Effects on Neurocognition

Aging | Cognitive Decline

United States
Massachusetts General Hospital

Recruiting

TMS in Preclinical and Prodromal AD: Modulation of Brain Networks and Memory

Alzheimer Disease | Aging | Mild Cognitive Impairment

United States
University of Florida
University of Arizona

Recruiting

Non-invasive Nerve Stimulation and Cognitive Training to Improve Cognitive Performance in Healthy Older Adults

Aging

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI); National Institute on Aging... and other collaborators

Recruiting

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults (PREVENTABLE)

Cardiovascular Diseases | Dementia | Cognitive Impairment, Mild

United States, Puerto Rico
Air Force Military Medical University, China

Recruiting

Postoperative Cognitive Function and EEG (POEM)

Postoperative Cognitive Dysfunction | Aging | EEG With Periodic Abnormalities

China
University of Maryland, Baltimore
Baltimore VA Medical Center; University of Maryland, Baltimore County

Recruiting

Glucose Variability and Cognition in Prediabetes

Depression | PreDiabetes | Aging | Cognitive Decline | Functional Status | Glucose Metabolism Disorders (Including Diabetes Mellitus)

United States
Case Comprehensive Cancer Center

Recruiting

Transplant Wellness Clinic for Elderly or High Risk Patients Undergoing BMT

Lymphoma | Myeloma | Stem Cell Transplant Complications | Allogeneic and Autologous Stem Cell Transplant

United States
University of South Florida
National Institute on Aging (NIA); University of Florida; University of California... and other collaborators

Recruiting

The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia

Dementia | Mild Cognitive Impairment | Age-related Cognitive Decline

United States
University of Southern California
National Institute on Aging (NIA); Alzheimer's Therapeutic Research Institute; Alzheimer's Clinical Trials Consortium

Recruiting

Trial-Ready Cohort-Down Syndrome (TRC-DS) (TRC-DS)

Dementia | Alzheimer Disease | Down Syndrome

United States, Spain, United Kingdom
Gregory Jicha, MD, PhD
National Institute on Aging (NIA)

Recruiting

Safety and Modulation of ABCC9 Pathways by Nicorandil for the Treatment of Hippocampal Sclerosis of Aging (SMArT-HS)

Dementia | Mild Cognitive Impairment

United States
University of Maryland, Baltimore
National Institute on Aging (NIA)

Recruiting

Exercise Plus Duloxetine for Knee Osteoarthritis

Depression | Knee Osteoarthritis

United States
VA Office of Research and Development

Recruiting

GOALS Cognitive Training Delivered to Aging Veterans in Person or Via Telehealth (TeleGOALS)

Brain Injuries, Traumatic | Executive Dysfunction

United States
University of Calgary
Canadian Institutes of Health Research (CIHR); Canadian Consortium on Neurodegeneration...

Recruiting

Trial of Remote Ischemic Pre-conditioning in Vascular Cognitive Impairment (TRIC-VCI)

Cerebral Small Vessel Diseases | Vascular Dementia | Vascular Cognitive Impairment | Cerebral Small Vessel Ischaemic Disease

Canada
University of Southern California
National Institute on Aging (NIA)

Recruiting

Advancing Postmenopausal Preventive Therapy (APPT)

Atherosclerosis | Cognitive Decline

United States
Columbia University
Boston University; Johns Hopkins University; University of California, Berkeley; University of Miami and other collaborators

Recruiting

Metformin in Alzheimer's Dementia Prevention (MAP)

Mild Cognitive Impairment

United States
Icahn School of Medicine at Mount Sinai
National Institute on Aging (NIA); Rutgers University

Recruiting

The Long-term Impact of a Light Intervention on Sleep and Cognition in Mild Cognitive Impairment

Mild Cognitive Impairment | Alzheimer's Disease

United States
St. Joseph's Hospital and Medical Center, Phoenix
The Cleveland Clinic; National Institute on Aging (NIA)

Recruiting

MCLENA-1: A Clinical Trial for the Assessment of Lenalidomide in Amnestic MCI Patients (MCLENA-1)

Cognitive Dysfunction | Neurodegeneration | Cognitive Impairment, Mild | Amyloid Plaque | Inflammation, Brain

United States
University of Florida
National Institute on Aging (NIA); University of Arizona

Recruiting

The Revitalize Study in Older Adults at Risk for Alzheimer's Disease

Cognitive Aging | Alzheimer Disease, Protection Against

United States
Universita di Verona

Recruiting

Successful Aging and Frailty (SAFe)

Cognitive Impairment | Sarcopenia | Frailty Syndrome

Italy
University of Arizona
National Institute on Aging (NIA)

Recruiting

Enhancement of Hippocampal Plasticity Using Repetitive Transcranial Magnetic Stimulation

Mild Cognitive Impairment

United States
Natalie Denburg

Recruiting

Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging

Healthy Aging | Mild Cognitive Impairment | Cognitive Decline

United States
Vivoryon Therapeutics N.V.
National Institute on Aging (NIA); Alzheimer's Disease Cooperative Study (ADCS)

Recruiting

A Trial to Evaluate the Efficacy and Safety of PQ912 in Patients With Early AD (VIVA-MIND)

Alzheimer Disease

United States

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