Search clinical trials for: Metered-dose inhaler (MDI)

Total 1631 results

University of Calgary
Canadian Institutes of Health Research (CIHR); The Arthritis Society, Canada; Smith and Nephew (formerly Oratec Interventions)

Completed

Electrothermal Arthroscopic Capsulorrhaphy (ETAC) and Open Inferior Capsular Shift in Patients With Shoulder Instability

Shoulder Dislocation

Canada
AstraZeneca

Completed

A Study to Compare the Pharmacokinetics of Budesonide Delivered by PT027 Compared With Pulmicort Flexhaler (ELBRUS)

Relative Bioavailability

United States
Research in Real-Life Ltd
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Device Mixing in Asthma, a General Practice Research Database Study (EBsalbutamol)

Asthma

United Kingdom
Bond Avillion 2 Development LP

Completed

A Study to Assess the Efficacy and Safety of Budesonide/Albuterol Metered-dose Inhaler (BDA MDI/PT027) in Adults and Children 4 Years of Age or Older With Asthma (MANDALA)

Asthma

United States, Canada, Germany, Spain, South Africa, United Kingdom, Slovakia, Argentina, Ukraine, Serbia, Czechia
Pearl Therapeutics, Inc.

Withdrawn

Efficacy and Safety of Two Doses of Formoterol Fumarate MDI (PT005) in Patients With Stable Chronic Obstructive Pulmonary Disease (COPD), Compared to Foradil® Aerolizer® as an Active Control

COPD

United States
GlaxoSmithKline

Not yet recruiting

A Study to Compare the Relative Potency of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152a to HFA-134a in Mild Asthmatics Aged 18 to 65 Inclusive

Asthma | Mild Asthma
Sanofi

Completed

Insulin Glargine Plus Insulin Glulisine Multiple Daily Injections (MDI) Versus Premix Insulin Treatment in Subjects With Diabetes Mellitus (Type 1 or Type 2)

Diabetes Mellitus

United States
Boehringer Ingelheim

Completed

Comparison of Safety and Efficacy of Berodual® Administered Via the Respimat® Device With That Administered Via the Metered Dose Inhaler (MDI) in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive
University of Virginia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); DexCom... and other collaborators

Recruiting

Artificial Pancreas - Adolescent Physiology & Psychology Longitudinal Evaluation (AP APPLE)

Type 1 Diabetes

United States
University of Virginia
National Library of Medicine (NLM)

Completed

CloudConnect: Predictive And Retrospective Clinical Decision Support For Chronic Disease Management

Type 1 Diabetes Mellitus

United States
University of Virginia
DexCom, Inc.; Tandem Diabetes Care, Inc.; Jaeb Center for Health Research

Completed

A Study of t:Slim X2 With Control-IQ Technology (DCLP5)

Type 1 Diabetes Mellitus

United States
GlaxoSmithKline

Not yet recruiting

A Study to Compare the Pharmacokinetics (PK) of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152A (Test) or HFA-134A (Reference) in Healthy Participants Aged 18 to 55 Inclusive

Asthma | Healthy Participants

Netherlands
University of North Carolina, Chapel Hill
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Budesonide Versus Fluticasone for Treatment of Eosinophilic Esophagitis

Eosinophilic Esophagitis

United States
DexCom, Inc.

Completed

Efficacy of Continuous Glucose Monitoring in Subjects With Type 1 Diabetes Mellitus on Multiple Daily Injections (MDI) or Continuous Subcutaneous Insulin Infusion (CSII) Therapy

Type 1 Diabetes Mellitus

United States
Centre national de recherche et de formation sur...
Programme national de lutte contre le paludisme (PNLP), Burkina Faso; Unité... and other collaborators

Unknown

Evaluation of Three Artemisinin-based Combinations for the Treatment of Uncomplicated Malaria in Childreen in Burkina Faso (CHIMIO2) (CHIMIO2)

Malaria | Burkina Faso

Burkina Faso
Medical University of Warsaw

Completed

Optimal Type of Inhaler in Cough Variant- or Cough Predominant Asthma

Asthma | Cough Variant Asthma

Poland
Organon and Co
Novartis

Completed

A Patient Handling Study of Mometasone Furoate/Formortoral Fumarate (MF/F) Metered Dose Inhaler (MDI) With an Integrated Dose Counter in Adolescent and Adult Subjects With Asthma or Chronic Obstructive Pulmonary Disease (Study P04703AM1)

Asthma | COPD
Chiesi Farmaceutici S.p.A.

Completed

Evaluation of Possible Effects on the QTc Interval of CHF 4226 pMDI in Healthy Volunteers (CT14)

Chronic Obstructive Pulmonary Disease

United States
Nemours Children's Clinic

Completed

Insulin Pump Therapy in Adolescents With Newly Diagnosed Type 1 Diabetes (T1D)

Diabetes Mellitus, Insulin-Dependent

United States
Boehringer Ingelheim

Completed

Serial Lung Function Measurements in Healthy and Mild Asthmatic Adults After Oral Inhalation of Ethanolic Solutions Containing Two Concentrations of the Excipient Butylated Hydroxytoluene (BHT) Administered With the Respimat® B (RMT-B)

Asthma
Hoffmann-La Roche

Completed

ACCU-CHEK® Aviva Expert Study: Does Use of a Bolus Advisor Improve Glycemic Control in Patients Not Achieving Optimal Control Using Multiple Daily Injections (MDI)? (ABACUS)

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1

Germany, United Kingdom
Bond Avillion 2 Development LP

Completed

To Compare the Pharmacokinetics of Budesonide Delivered by BDA MDI to Budesonide Delivered by Pulmicort Respules in Children With Asthma Aged 4 to 8 Years. (BLANC)

Asthma

United States
Rabin Medical Center
Harvard University; DreaMed

Terminated

Determination of Automated Multiple Insulin Dose Injections Settings Using the MDI/SMBG Advisor for Patients With Type 1 Diabetes -Data Collection, Observational & Proof of Concept Study

Type 1 Diabetes | Multiple Daily Injections

Israel
Concentrx Pharmaceuticals, Inc.
PharPoint Research, Inc.; Kramer Consulting, LLC

Completed

Safety and Efficacy of Albuterol Administered by the Halix™ Dry Powder Inhaler in Subjects With Asthma

Asthma

United States
Boehringer Ingelheim

Completed

Respimat® Combivent Trial in Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

United States, Argentina, France, Greece, Korea, Republic of, New Zealand, Poland, Russian Federation, South Africa, Taiwan, Turkey, Ukraine, United Kingdom
Chiesi Farmaceutici S.p.A.

Completed

An 8-week Dose Ranging Study of CHF 718 pMDI in Asthmatic Subjects (BEAM)

Asthma

United States
Yonsei University

Terminated

Adenosine-induced Stress Dynamic Myocardial Perfusion Imaging With Dual-source CT

Coronary Artery Disease

Korea, Republic of
Boehringer Ingelheim
Pfizer

Completed

Evaluation of Tiotropium 2.5 and 5 mcg Once Daily Delivered Via the Respimat® Inhaler Compared to Placebo and Salmeterol HydroFluoroAlkane (HFA) Metered Dose Inhaler (MDI) (50 mcg Twice Daily) in Patient With Moderate Persistent Asthma II

Asthma

United States, Brazil, China, Colombia, Germany, India, Japan, Mexico, Peru, Poland, Romania
Boehringer Ingelheim
Pfizer

Completed

Evaluation of Tiotropium 2.5 and 5 mcg Once Daily Delivered Via the Respimat® Inhaler Compared to Placebo and Salmeterol HydroFluoroAlkane (HFA) Metered Dose Inhaler (MDI) (50 mcg Twice Daily) in Patient With Moderate Persistent Asthma I

Asthma

United States, Brazil, China, Guatemala, India, Japan, Latvia, Mexico, Peru, Poland, Russian Federation
Suez Canal University

Completed

Salbutamol Administration by Nebulizer Versus Metered Dose Inhaler With Spacer in Asthma in Children

Bronchial Asthma

Egypt
Amphastar Pharmaceuticals, Inc.

Completed

Evaluation of Efficacy and Safety for Single Dose of E004 in Children With Asthma

Asthma

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Comparison of Two Bronchodilator Inhalers in Adolescents and Adults With Exercise-Induced Asthma

Exercise-induced Bronchospasm

United States
NorthShore University HealthSystem

Completed

The Use of the Propeller Health Platform to Improve Inhaled Corticosteroid (ICS) Use Among Adults With Uncontrolled Persistent Asthma

Asthma

United States
University of Virginia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Feasibility of a Decision Support System to Reduce Glucose Variability in Subject With T1DM

Type 1 Diabetes Mellitus

United States
Hoffmann-La Roche

Completed

Participant-Reported Outcomes With the Accu-Chek® Solo Micropump System (PRO Solo)

Diabetes Mellitus, Type 1

Austria, Germany, Poland, United Kingdom
Kilimanjaro Clinical Research Institute
London School of Hygiene and Tropical Medicine; Ifakara Health Institute

Unknown

The Optimal Timing Of Primaquine To Prevent Malaria Transmission After Artemisinin-Combination Therapy

Malaria Transmission

Tanzania
Research in Real-Life Ltd
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Real-life Effectiveness and Cost-effectiveness of Qvar Versus FP and BDP in the Management of COPD (QvarCOPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
Nemours Children's Clinic

Completed

Dose-response of Albuterol in Asthmatics

Asthma

United States
GlaxoSmithKline

Completed

A Study to Evaluate the Effect of Umeclidinium (UMEC) as Combination Therapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany, Netherlands, Greece, Czechia
Steen Andersen
Medtronic

Completed

Effect of CSII and CGM on Progression of Late Diabetic Complications

Type 1 Diabetes Mellitus

Denmark
Science Consulting in Diabetes
DexCom, Inc. a Delaware corporation, USA; Institut für Diabetes-Technologie...

Completed

Real-Time Continuous Glucose Monitoring (RT-CGM) in Patients With Type 1 Diabetes at High Risk for Low Glucose Values Using Multiple Daily Injections (MDI) in Germany (HYPODE-STUDY)

Diabetes

Germany
Boehringer Ingelheim

Completed

Flow Rate Effect Respimat Inhaler Versus a Metered Dose Inhaler Using Berodual in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive | Asthma

Germany
Boehringer Ingelheim

Completed

A Six-week Study Comparing the Efficacy and Safety of Tiotropium Plus Formoterol to Salmeterol Plus Fluticasone in Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany, Netherlands, Denmark, France, South Africa, Austria, Belgium, Sweden
Organon and Co

Completed

Study of Mometasone Furoate/Formoterol Combination and Fluticasone/Salmeterol in Persistent Asthmatics Previously Treated With Inhaled Glucocorticosteroids (P04139)

Asthma
AstraZeneca

Completed

A Study to Assess the Pulmonary Distribution of Budesonide, Glycopyrronium and Formoterol Fumarate

Pulmonary Disease, Chronic Obstructive

United Kingdom
University of Virginia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Active, not recruiting

Adapting Diabetes Treatment Expert Systems to Patient in Type 1 Diabetes (DSS-2)

Diabetes Mellitus, Type 1

United States
Hoffmann-La Roche

Completed

European, Open-label, Prospective, Multinational, Multicenter Study in Adult Subjects With Type 1 or Type 2 Diabetes Previously on MDI or CSII Therapy. Subjects Home Setting is Considered Routine Practice.

Type 2 Diabetes, Type 1 Diabetes

Austria, United Kingdom
Sunovion

Completed

Dose Response Study of Levalbuterol in the Prevention of Exercise Induced Bronchoconstriction Compared to Racemic Albuterol

Asthma | Bronchoconstriction

United States
Boehringer Ingelheim

Completed

Free Combinations of Tiotropium Inhalation Powder Capsule + Salmeterol Metered Dose Inhaler, Tiotropium Inhalation Powder Capsule and Salmeterol Metered Dose Inhaler in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline

Completed

A Phase III Parallel Group Study, Comparing the Efficacy, Safety and Tolerability of the Fixed Dose Combination (FDC) of Fluticasone Furoate+Umeclidinium Bromide+Vilanterol (FF/UMEC/VI) With the FDC of FF/VI in Subjects With Inadequately Controlled Asthma

Asthma

Australia, United States, Argentina, Canada, Germany, Japan, Korea, Republic of, Romania, Russian Federation, Spain, South Africa, Netherlands, Poland, Italy, United Kingdom

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