Search clinical trials for: Population pharmacodynamics

Total 6006 results

Central South University

Recruiting

Clinical Study of Individualized Vancomycin Dosing Based on Population PK Model

Severe Infection

China
University Hospitals Coventry and Warwickshire...

Recruiting

The Costs and Effectiveness of Cognitive Functional Therapy for People With Persistent Low Back Pain in Coventry.

Low Back Pain

United Kingdom
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

A Clinical Trial Evaluated the Safety and Tolerability, Pharmacokinetic and Pharmacodynamics Profile, and Immunogenicity of a Single Dose of JS010 Injection in Healthy Subjects

Migraine

China
University Hospital, Montpellier

Recruiting

Adapting Mindful Eating Program for French Overweight/Obese Population (MIND-EAT)

Overweight and Obesity

France
JMackem Co., Ltd
Seoul National University Hospital

Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Oral Administration of AJH-2947 in Healthy Korean and/or Caucasian Adult Male Subjects

Diabetic Neuropathies | Neuropathic Pain | Post Herpetic Neuralgia

Korea, Republic of
Wuhan Union Hospital, China

Not yet recruiting

Clinical Controlled Study on the Efficacy of Denosumab in Treating Osteoporosis in the Domestic Population and Its Impact on Sarcopenia-related Outcomes

Sarcopenia | Osteoporosis | Denosumab

China
Charles University, Czech Republic

Recruiting

PAMNEU - Memory in Neurology

Cognitive Impairment

Czechia
University of Saskatchewan

Not yet recruiting

Examining the Effects of a Remote Pulmonary Rehabilitation Program in the Severe Asthma Population. (STAPLE)

Asthma
Ionis Pharmaceuticals, Inc.

Recruiting

Orbit Study: A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Intrathecally Administered ION356 in Participants With Pelizaeus Merzbacher Disease (PMD)

Pelizaeus-Merzbacher Disease

France, Netherlands
Ministry of Health and Population, Egypt
Cairo University

Recruiting

Effect of Pilates Exercises and Diaphragm Manual Therapy Techniques in Rotator Cuff Tendinopathy

Shoulder Rotator Cuff Tendinopathy | Shoulder Tendinitis

Egypt
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Safety, Tolerability, Drug Levels, Food, Formulation, and pH Effects on Relative Absorption of BMS-986465 and Its Active Derivative BMS-986464 in Healthy Participants

Healthy Participants

United States
Gubra A/S
Quotient Sciences

Recruiting

A First-In-Human Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GUB014295

Overweight | Healthy Volunteers

United Kingdom
Population Health Research Institute

Not yet recruiting

Single Dose Flecainide for Early Sinus Rhythm Conversion of Perioperative Atrial Fibrillation After Noncardiac Surgery (FLIP-AF)

Atrial Fibrillation | Surgery
University of Minnesota

Recruiting

The HAPPINESS Trial: cHAnging the Perceived Pain INtensity in divErSe Populations With Spinal Cord Injury

Spinal Cord Injuries

United States
Koç University

Not yet recruiting

The Feasibility of Cognitive Process Therapy in Earthquake-affected Population With Mental Health Problems in Türkiye

Depressive Symptoms | Post Traumatic Stress Disorder | Anxiety Disorders and Symptoms | Well-Being, Psychological
Tianjin Third Central Hospital
BGI, China

Recruiting

A Prospective Study on the Application of Liquid Biopsy in the Surveillance of High-risk Population of HCC.

Hepatocellular Carcinoma

China
AstraZeneca

Recruiting

A Single and Multiple Ascending Dose Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD2389 in Healthy Participants

Healthy Participants

United States
ANRS, Emerging Infectious Diseases
Programme PAC-CI; Centre Population et Développement (CEPED/IRD)

Recruiting

Feasibility and Effectiveness of a Pilot Program of Physical Activity to Improve HIV Related Functional Limitations and Disability in Adults Aged 40 and Older From Côte d'Ivoire (VIRAGE+)

HIV Infections

Côte D'Ivoire
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Population Pharmacokinetics of Paracetamol in Overweight and Obese Children (PARAENFO)

Obesity | Overweight

France
AstraZeneca
Parexel

Recruiting

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD6234 After Repeat Dose Administration in Participants Who Are Overweight or Obese

Healthy Participants

United States, United Kingdom, Germany
University Hospital, Caen

Not yet recruiting

IRAF-ABLATION Study: a Multicenter International Retrospective Cohort of Patients With BTK Inhibitors-related AF Treated by Catheter Ablation

Hematologic Malignancy | BTKi-induced Atrial Fibrillation | Atrial Fibrillation Catheter Ablation

France
PATH
London School of Hygiene and Tropical Medicine; Monash University; University... and other collaborators

Not yet recruiting

Assessing the Acceptability, Feasibility, Effectiveness and Cost-effectiveness of LADB

Opioid Dependence
Sohag University

Recruiting

Prevalence and Pathological Features of C3 Dominant Glomerulonephritis Among Egyptian Population

C3 Nephropathy

Egypt
Peking University People's Hospital

Not yet recruiting

Endometrial Cancer Screening in High-risk Populations

Cancer Screening
Bristol-Myers Squibb

Recruiting

Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) (AURORA-HFpEF)

Heart Failure

United States, Spain, Canada, Italy, Poland
AstraZeneca
Parexel

Recruiting

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4144 Following Single and Multiple Ascending Doses Via Oral Administration to Healthy Participants

Healthy Participants

United States
Intercept Pharmaceuticals

Not yet recruiting

Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Obeticholic Acid (OCA) Compared to Placebo in Pediatric Participants With Biliary Atresia, Post-hepatoportoenterostomy

Biliary Atresia
Biocad

Recruiting

Study of the Safety, Pharmacodynamics and Efficacy of ANB-002 in Patients With Hemophilia B (SAFRAN)

Hemophilia B

Russian Federation
CanSino Biologics Inc.

Recruiting

A Clinical Trial to Evaluate the Safety and Immunogenicity of a Single Dose of Adsorbed Tetanus Vaccine in a Population Aged 18 Years and Over

Tetanus

China
Singapore Institute for Clinical Sciences
OBVIO HEALTH USA, Inc.

Recruiting

Novel Objective Digital Biomarkers for Assessing Sub-clinical Mood Disturbances in the Singaporean Population

Mood

Singapore
AstraZeneca

Recruiting

A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics of Subcutaneous AZD6912 in Healthy Participants

Rheumatoid Arthritis

United Kingdom, Canada
Duke University

Not yet recruiting

Nutrition and Obesity in Under-Represented Populations: Food Insecurity Research to Advance Science and Improve Health (NOURISH)

Pediatric Obesity | Food Insecurity | Nutrition Poor | Nutrition, Healthy
Ohio State University Comprehensive Cancer Center

Recruiting

Evaluation of an Education Program to Increase Knowledge and Participation in Clinical Trials Among Racial/Ethnic and Rural Populations

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm

United States
Direction Centrale du Service de Santé des Armées

Not yet recruiting

Evaluation of the Consequences of Poly Vaccination on Innate Immunity : Applications to a Military Population (VaxInnate)

Vaccine Breakthrough Infections
Columbia University

Not yet recruiting

Telehealth-Based Intervention to Detect and Manage Glaucoma Among High-Risk Populations (NYC-SIGHT-2)

Adherence to In-Office Glaucoma Evaluation Appointment
Centre Hospitalier St Anne

Recruiting

Use of tDCS Applied to the Orbitofrontal Cortex to Improve Risky Decision-making in a Clinical Population (tDCSDeMOStim)

Depression | Mood Disorders | Suicide

France
Beijing InnoCare Pharma Tech Co., Ltd.

Recruiting

Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of ICP-488 in Patients With Moderate to Severe Plaque Psoriasis

Moderate to Severe Plaque Psoriasis

China
Cedars-Sinai Medical Center
National Institute on Aging (NIA)

Not yet recruiting

Population Health Approach to Optimizing Medications in Older Adults (POP-MED)

Medication Adverse Effects
University Hospital, Strasbourg, France

Recruiting

Hematological Effects of Atypical Antipsychotics (AAPs) in a Geriatric Population: What is the Role of 5-HT2 Receptors (AAPs)

Neutropenia

France
Hoffmann-La Roche

Recruiting

A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamics Of Satralizumab In Participants With Thyroid Eye Disease (SatraGO-2) (SatraGO-2)

Thyroid Eye Disease

Korea, Republic of, United Kingdom, United States, Canada, China, Israel, France, Spain
COUR Pharmaceutical Development Company, Inc.

Recruiting

Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of CNP-106 in Subjects With Myasthenia Gravis

Myasthenia Gravis | Generalized Myasthenia | AChR Myasthenia Gravis | MuSK MG

United States
Bern University of Applied Sciences
Haute Ecole de Santé Vaud

Not yet recruiting

Back Beliefs Among the General Population

Low Back Pain
Connecticut Children's Medical Center
University of Connecticut

Recruiting

Application of Virtual Reality in Post-Operative Recovery of a Pediatric Scoliosis Patient Population

Adolescent Idiopathic Scoliosis

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Oriental Intervention for Enhanced Neurocognitive Health (Orient) Diet in Populations With High Risk of Stroke (ENDS)

High Risk of Stroke

China
China National Center for Cardiovascular Diseases
Innovent Biologics, Inc.

Not yet recruiting

Early Initiation of Tafolecimab for Patients With Acute Coronary Syndromeundergoing Percutaneous Coronary Intervention in Chinese Population

Acute Coronary Syndrome | Non ST Segment Elevation Acute Coronary Syndrome
Valenta Pharm JSC

Not yet recruiting

Comparative Pharmacodynamics and Pharmacodynamics Equivalence of Antareit 800 mg/10 ml Oral Suspension and Riopan 800 mg Chewable Tablets in Healthy Volunteers

Heartburn | Acid-dependent Diseases of the Gastrointestinal Tract | Symptomatic Treatment of Gastric and Duodenal Ulcers

Russian Federation
Shanghai First Maternity and Infant Hospital

Recruiting

Prediction of Placental Fetal Growth Restriction in High Risk Population (PoPFGR)

Fetal Growth Retardation

China
Royal College of Surgeons, Ireland

Not yet recruiting

Assessing the Feasibility of a Coach-led Digital Platform (Connect5)

Life Style, Healthy | Population

Ireland
G2GBio, Inc.

Recruiting

Dose-Escalation, Single Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GB-6002 Local Infiltration in Healthy Male Adults

Pain, Postoperative

Korea, Republic of
University of Pennsylvania

Recruiting

Improving Sleep in the Neurology In-Patient Population (I_SLEEP)

Sleep

United States

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