Search clinical trials for: grade IV astrocytoma

Total 23075 results

M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain Tumors

Glioblastoma | WHO Grade III Glioma | WHO Grade II Glioma

United States
Sapience Therapeutics

Recruiting

A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors

Breast Cancer | Glioblastoma | Prostate Cancer | Brain Cancer | Glioblastoma Multiforme | GBM | Metastatic Breast Cancer | Recurrent Glioblastoma | Metastatic Melanoma | Metastatic Prostate Cancer | Prostate Cancer Metastatic | Newly Diagnosed Glioblastoma | Melanoma Stage IV | Melanoma Recurrent

United States, United Kingdom
Joseph Tuscano
National Cancer Institute (NCI); Genentech, Inc.; Pharmacyclics LLC.

Recruiting

Obinutuzumab, Ibrutinib, and Venetoclax for the Treatment of Previously Untreated Stage II-IV Follicular Lymphoma

Ann Arbor Stage II Follicular Lymphoma | Ann Arbor Stage III Follicular Lymphoma | Ann Arbor Stage IV Follicular Lymphoma | Grade 1 Follicular Lymphoma | Grade 2 Follicular Lymphoma | Grade 3a Follicular Lymphoma

United States
Fondazione Italiana Linfomi ONLUS
GRADE Onlus

Recruiting

Prephase Treatment With Prednisone +/- Vitamin D Supplementation Followed by Immunochemotherapy (FIL_PREVID)

Diffuse Large B-Cell Lymphoma | Elderly Patients

Italy
Nader Sanai
Eli Lilly and Company; Barrow Neurological Institute; Ivy Brain Tumor Center

Recruiting

LY3214996 Plus Abemaciclib in Recurrent Glioblastoma Patients

Glioma | Glioblastoma | GBM

United States
Vrije Universiteit Brussel
Universitair Ziekenhuis Brussel; AZ St.-Dimpna Geel

Recruiting

Exercise Therapy for Osteoarthritis Pain: How Does it Work? (KOA-PAIN)

Knee Osteoarthritis

Belgium
Sabine Mueller, MD, PhD
Pacific Pediatric Neuro-Oncology Consortium

Recruiting

Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults

Glioblastoma | Malignant Glioma | Recurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent Grade III Glioma | Grade III Glioma

United States, Australia, Israel, Switzerland
Erasmus Medical Center
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Leiden University... and other collaborators

Recruiting

Radiotherapy in IDH Mutated Glioma: Evaluation of Late Outcomes (RIGEL)

Oligodendroglioma | Astrocytoma, Grade III | Astrocytoma, Grade II | Oligodendroglioma, Anaplastic

Netherlands
Memorial Sloan Kettering Cancer Center
Agios Pharmaceuticals, Inc.

Recruiting

AG-120 in People With IDH1 Mutant Chondrosarcoma

Chondrosarcoma | IDH1 Gene Mutation | Chondrosarcoma, Grade 2 | Chondrosarcoma, Grade 3

United States
Beijing Sanbo Brain Hospital

Recruiting

Study of Recombinant Human Endostatin Combined With Temozolomide and Irinotecan in Recurrent Gliomas

Glioblastoma, Recurrent | Lower Grade Glioma, Recurrent

China
Pirogov Russian National Research Medical University

Recruiting

Elastic Compression Stockings and Varicose Veins Recurrence (ECOS-VVR)

Varicose Veins | Chronic Venous Insufficiency

Russian Federation
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MMP2+ Recurrent or Progressive Glioblastoma

Recurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent WHO Grade III Glioma | Recurrent WHO Grade II Glioma

United States
Geisinger Clinic

Recruiting

Neoadjuvant Chemoradiation for Resectable Glioblastoma (NeoGlio)

Glioblastoma | High Grade Glioma | Surgery

United States
National Cancer Institute (NCI)

Recruiting

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Low Grade Glioma | Low Grade Astrocytoma | Metastatic Low Grade Astrocytoma | Metastatic Low Grade Glioma

United States, Canada, Puerto Rico
Baylor College of Medicine
Center for Cell and Gene Therapy, Baylor College of Medicine; The Faris Foundation and other collaborators

Recruiting

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

High Grade Glioma | Diffuse Intrinsic Pontine Glioma | Embryonal Tumor | Ependymal Tumor

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Stage III Fallopian Tube Cancer AJCC v8 | Stage III Ovarian Cancer AJCC v8 | Stage III Primary Peritoneal Cancer AJCC v8 | Stage IV Fallopian Tube Cancer AJCC v8 | Stage IV Ovarian Cancer AJCC v8 | Stage IV Primary Peritoneal Cancer AJCC v8 | Stage II Fallopian Tube Cancer AJCC v8 | Stage II Ovarian... and other conditions

United States, Canada, Korea, Republic of, Puerto Rico, Ireland
St. Jude Children's Research Hospital

Recruiting

Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma

Glioma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Pilocytic Astrocytoma | Optic Pathway Glioma | Pilomyxoid Astrocytoma

United States
Shanghai Children's Medical Center
Chinese University of Hong Kong; Nanfang Hospital of Southern Medical University and other collaborators

Recruiting

TCDαβ/CD45RA Haploidentical Transplantation in Children With Leukemia

Relapsed Pediatric AML | Relapsed Pediatric ALL | Acute Graft-Versus-Host Disease (Gvhd) Grade IV (Diagnosis)

China
Novartis Pharmaceuticals

Recruiting

Pediatric Long-Term Follow-up and Rollover Study

Glioblastoma | Astrocytoma | Anaplastic Astrocytoma | Neurofibromatosis Type 1 | Anaplastic Ganglioglioma | Anaplastic Pleomorphic Xanthoastrocytoma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Gangliocytoma | Central Neurocytoma | Oligodendroglioma... and other conditions

United States, Belgium, Spain, Denmark, Germany, Czechia, Italy, Australia, Russian Federation, France, Brazil, Netherlands, Japan, Canada, Finland, Sweden, United Kingdom, Argentina, Israel
National Cancer Institute (NCI)

Recruiting

Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma

Glioblastoma | Malignant Glioma | Anaplastic Astrocytoma | Anaplastic Astrocytoma, Not Otherwise Specified | Anaplastic Ganglioglioma | Anaplastic Pleomorphic Xanthoastrocytoma | WHO Grade 3 Glioma

United States, Puerto Rico
M.D. Anderson Cancer Center
DNAtrix, Inc.

Recruiting

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

Recurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent Gliosarcoma | Recurrent Anaplastic Astrocytoma | IDH1 wt Allele

United States
Wuerzburg University Hospital

Recruiting

Autologous Dendritic Cells, Metronomic Cyclophosphamide and Checkpoint Blockade in Children With Relapsed HGG

Childhood Glioblastoma

Germany
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Recruiting

Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases

Glioma | Astrocytoma | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Oligodendroglioma | Recurrent Glioma | Invasive Breast Carcinoma | Breast Carcinoma Metastatic in the Brain

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI); Pinnacle Biologics Inc.; Simphotek Inc.

Recruiting

Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer

Small Cell Lung Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8 | Non-Small Cell Lung Carcinoma | Locally Advanced Lung Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotype

Glioma | Glioblastoma | Malignant Glioma | Low Grade Glioma | High Grage Glioma

United States
Haukeland University Hospital
University of Oslo; Oslo University Hospital; University Hospital of North Norway and other collaborators

Recruiting

Bortezomib and Temozolomide in Recurrent Grade-4 Glioma Unmethylated MGMT Promoter (BORTEM-17) (BORTEM-17)

Glioblastoma

Norway
David Baskin MD
Center for Cell and Gene Therapy, Baylor College of Medicine

Recruiting

HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM

Glioblastoma Multiforme | Astrocytoma, Grade III

United States
Catalysis SL

Recruiting

Evaluation Glizigen® and Ocoxin®-Viusid® in High-grade Cervical Intraepithelial Lesions

Neoplasms | Carcinoma | Neoplasia; Intraepithelial, Cervix | Glandular Neoplasms | Epithelial Neoplasm

Cuba
Novartis Pharmaceuticals

Recruiting

Dabrafenib and/or Trametinib Rollover Study

Melanoma | Solid Tumor | High Grade Glioma | Non Small Cell Lung Cancer | Rare Cancers

Spain, Germany, United States, Argentina, Austria, Denmark, France, Hungary, Netherlands, China, Japan, Thailand
Sidney Kimmel Cancer Center at Thomas Jefferson...
Genentech, Inc.; Pharmacyclics LLC.

Recruiting

Obinutuzumab and Ibrutinib as Front Line Therapy in Treating Patients With Indolent Non-Hodgkin's Lymphomas

Non-Hodgkin's Lymphoma | Indolent Non-hodgkin Lymphoma | Ann Arbor Stage II Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue | Ann Arbor Stage II Follicular Lymphoma | Ann Arbor Stage II Nodal Marginal Zone Lymphoma | Ann Abor Stage III B-Cell Non-Hodgkin Lymphoma | Ann Arbor... and other conditions

United States
Sun Yat-sen University

Recruiting

A Study on β-elemene as Maintain Treatment for Newly Diagnosed Malignant Gliomas (β-elemene)

Glioblastoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma

China
Ivan de Kouchkovsky, MD
National Cancer Institute (NCI); American Cancer Society, Inc.; National Institute...

Recruiting

Pilot Study of (MR) Imaging With Pyruvate (13C) to Detect High Grade Prostate Cancer (pyruvate)

Prostate Cancer

United States
Dana-Farber Cancer Institute
Merck Sharp & Dohme LLC; National Institutes of Health (NIH); Accelerate Brain... and other collaborators

Recruiting

Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM

Glioblastoma

United States
Julie Krystal
Janssen Pharmaceuticals

Recruiting

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

Glioblastoma Multiforme | Gliosarcoma | Anaplastic Astrocytoma | Pleomorphic Xanthoastrocytoma | Pilocytic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Low-grade Glioma | DIPG | Brainstem Glioma | Optic Nerve Glioma | Pilomyxoid Astrocytoma | Glioma, Astrocytic

United States
Sun Yat-sen University

Recruiting

Efficacy of Post-radiation Adjuvant Temozolomide Chemotherapy in Residue Low-grade Glioma

Astrocytoma | Oligodendroglioma | Oligodendroastrocytoma

China
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Nonmalignant Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Registry of Older Patients With Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Cognitive/Functional Effects | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Canadian Cancer Trials Group; European Organisation...

Recruiting

Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma

Brain and Central Nervous System Tumors

United States, Canada, France, Netherlands, Austria, Belgium
SWOG Cancer Research Network
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; Cancer and...

Active, not recruiting

S0016 Combination Chemotherapy With Monoclonal Antibody Therapy in Newly Diagnosed Non-Hodgkin's Lymphoma

Lymphoma

United States
M.D. Anderson Cancer Center
Bristol-Myers Squibb; National Cancer Institute (NCI); Iovance Biotherapeutics

Active, not recruiting

Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Colorectal Cancer, or Pancreatic Ductal Adenocarcinoma

Malignant Solid Neoplasm | Metastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Platinum-Resistant Ovarian Carcinoma | Metastatic Pancreatic Ductal Adenocarcinoma | Metastatic Ovarian Carcinoma and other conditions

United States
Nicholas Butowski
National Cancer Institute (NCI); Celldex Therapeutics

Terminated

A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG)

Glioma | Malignant Glioma | Oligodendroglioma | Astrocytoma, Grade II | Glioma, Astrocytic | Oligoastrocytoma, Mixed

United States
National Cancer Institute (NCI)

Suspended

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

Diffuse Glioma | Secondary Glioblastoma | Glioblastoma, IDH-Wildtype | Astrocytoma, IDH-Mutant, Grade 4

United States, Puerto Rico
Thomas Hope

Completed

Fluoroethyltyrosine for Evaluation of Intracranial Neoplasms (UC-GlioFET)

Recurrent Glioblastoma | Recurrent WHO Grade III Glioma | Low Grade Glioma | Intracranial Neoplasm | Recurrent World Health Organization (WHO) Grade II Glioma

United States
National Cancer Institute (NCI)

Active, not recruiting

Telaglenastat With Radiation Therapy and Temozolomide in Treating Patients With IDH-Mutated Diffuse Astrocytoma or Anaplastic Astrocytoma

Astrocytoma, IDH-Mutant, Grade 2 | Astrocytoma, IDH-Mutant, Grade 3

United States
UroGen Pharma Ltd.

Terminated

A Phase 3 Study of UGN-102 for Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer (ATLAS)

Bladder Cancer | Urothelial Carcinoma Bladder | Urothelial Carcinoma

United States, Israel, Russian Federation, Georgia, Bulgaria, Estonia, Latvia, Poland, Serbia, Ukraine
National Cancer Institute (NCI)

Active, not recruiting

Carboplatin, Gemcitabine Hydrochloride, and Berzosertib in Treating Patients With Recurrent and Metastatic Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Stage IV Fallopian Tube Cancer AJCC v6 and v7 | Stage IV Ovarian Cancer AJCC v6 and v7 | Stage IV Primary Peritoneal Cancer AJCC v7 | Ovarian High Grade Serous Adenocarcinoma | Platinum-Sensitive... and other conditions

United States
St. Jude Children's Research Hospital
Novartis Pharmaceuticals

Completed

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Glioma | Neoplasms | Glioblastoma | Neoplasms, Neuroepithelial | Central Nervous System Neoplasms | Brain Cancer | Brain Tumor | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Pineoblastoma | Recurrent Medulloblastoma | CNS Tumor | Pediatric... and other conditions

United States
Dana-Farber Cancer Institute
Astellas Pharma Inc; Regeneron Pharmaceuticals

Active, not recruiting

ASP8374 + Cemiplimab in Recurrent Glioma

Glioblastoma | Recurrent Glioblastoma

United States
National Cancer Institute (NCI)
Children's Oncology Group

Active, not recruiting

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Rhabdoid Tumor | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Ann Arbor Stage III Hodgkin Lymphoma | Ann Arbor Stage IV Hodgkin Lymphoma | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent... and other conditions

United States, Puerto Rico
National Cancer Institute (NCI)
Children's Oncology Group

Active, not recruiting

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

Refractory Malignant Solid Neoplasm | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Glioma | Recurrent Malignant Solid Neoplasm | Recurrent Medulloblastoma | Recurrent Neuroblastoma and other conditions

United States, Puerto Rico, Australia

Search clinical trials for: grade IV astrocytoma

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