Search clinical trials for: understudied diseases

Total 376844 results

MSD Italia S.r.l.

Not yet recruiting

A Study to Describe the Diagnostic and Therapeutic Path of Patients with NSCLC in Early Stage and Locally Advanced (Key-Early)

NSCLC | Non-small Cell Lung Cancer | NSCLC, Stage III | NSCLC, Stage I
King's College Hospital NHS Trust
King's College London

Not yet recruiting

ESCALATion of Medical Therapy Following Multimodality Plaque Evaluation in High-risk Chronic Coronary Syndromes (ESCALATE)

Coronary Artery Disease
National Aeronautics and Space Administration (NASA)

Recruiting

Effect of Sex on Orthostatic Intolerance and Cardiovascular Response During Lunar Descent and Ascent (Lunar OI)

Healthy

United States
Sun Yat-sen University

Not yet recruiting

Neoadjuvant HAIC and PD-1 Plus Adjuvant PD-1 for High-risk Recurrent HCC

Hepatocellular Carcinoma | Beyond Milan Criteria
Tampere University Hospital
University of Turku; Kuopio University Hospital; Tampere University; University... and other collaborators

Not yet recruiting

Study on Female Patients' Mammographic Texture Features (COMPRESS)

Breast Cancer | Artificial Intelligence | Mammography
Shanghai Simnova Biotechnology Co.,Ltd.

Not yet recruiting

F01 in the Treatment of Moderate-to-severe Refractory Systemic Lupus Erythematosus

Lupus Erythematosis

China
Photofuse Pty Ltd
United States Department of Defense

Not yet recruiting

Acute Retinal Detachment Repair With the iSeelr™ Retinal Detachment Repair System

Rhegmatogenous Retinal Detachment - Macula Off

Australia
Assuta Ashdod Hospital

Not yet recruiting

Oxytocin Effectiveness in First Trimester Dilatation and Curettage - a Double Blind Placebo Controlled Randomized Trial

Missed Abortion
Changhai Hospital
Rui Therapeutics

Not yet recruiting

An Exploratory Clinical Study of Anti-CD19 CAR NK Cell (KN5501) in the Treatment of Relapsed/Refractory Immune Nephropathy

Nephropathy
Clinica Especializada en el Manejo de la Diabetes...

Recruiting

Multidisciplinary Care for Lifestyle Change for Metabolic Control and Quality of Life in Prediabetes (PreCPro) (PreCPro)

PreDiabetes

Mexico
Ain Shams University

Recruiting

Does Non-Steroidal Anti-inflammatory Drugs Decrease the Quality of Pleurodesis After Mechanical Pleural Abrasion/Pleurectomy for Treatment of Pneumothorax?

Primary and Secondary Spontaneous Pneumothorax

Egypt
Istanbul University

Not yet recruiting

Comparison of the Effectiveness of Stretching and Strengthening Exercises in Patients With Frozen Shoulder

Frozen Shoulder

Turkey
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian Cancers

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma

United States
First Affiliated Hospital of Xinjiang Medical University

Not yet recruiting

Efficacy of Local Antibiotic Injection Via a Catheter for Treating Acute Periprosthetic Infections After Knee DAIR Surgery (YES)

Local Antibiotic Injection Catheter Acute Periprosthetic Infections Knee DAIR Randomized Controlled Trial
GT Metabolic Solutions, Inc.

Recruiting

MagDI Canada Study

Obesity | Type 2 Diabetes

Canada
University of California, Davis
Knownwell

Recruiting

CRAVE Study: Comparing Craving Responses and Diet Quality of GLP1 Receptor Agonist Users

Obesity

United States
The First Affiliated Hospital with Nanjing Medical...

Recruiting

NALIRIFOX as Induction Therapy in LAPC

Pancreatic Ductal Adenocarcinoma

China
Cairo University

Recruiting

Efficacy of Cervical Stabilization Exercises on Hand Grip Strength in Chronic Myofascial Neck Pain

Chronic Neck Pain

Egypt
Sykehuset i Vestfold HF

Recruiting

Glucose Monitoring in Treatment of Postprandial Hypoglycemia After Bariatric Surgery (HypoBar)

Postprandial Hypoglycaemia After Bariatric Surgery

Norway
Universidade Federal Fluminense

Not yet recruiting

Evaluation of Chlorhexidine Gel Associated With Photodynamic Therapy in the Treatment in Diabetic Participants

Diabetes Mellitus, Type 2 | Periodontitis | Periodontitis, Adult

Brazil
United States Army Research Institute of Environmental...

Not yet recruiting

The Effects of Semaglutide on Body Composition and Performance in Military Personnel

Obesity
Peter Timoney
Inflammasome Therapeutics

Not yet recruiting

Evaluation of K9 in Subjects With Thyroid Eye Disease (TED)

Thyroid Eye Disease

United States
Fundación Pública Andaluza para la gestión de la...
Hospital Universitario Reina Sofia de Cordoba; Hospitales Universitarios Virgen...

Recruiting

Blood Biomarkers to Predict the Prognosis of a Stroke Patient Undergoing Mechanical Thrombectomy (TROMBOPOCT)

Acute Ischemic Stroke

Spain
Casa di Cura Dott. Pederzoli
University of Padova

Recruiting

First-day Versus Early Drain Removal Following PD: a Randomized Controlled Trial (FIDEL)

Pancreas Fistula Abdominal Drains

Italy
Peking University People's Hospital

Not yet recruiting

Fertility Sparing Therapy for Patients With Stage IA G2 Endometrial Cancer

Carcinoma, Endometrioid | Fertility Preservation
Azienda Ospedaliero Universitaria Maggiore della...

Not yet recruiting

Artificial Intelligence-based Platform, Integrating Pathologic, Imaging and Molecular Profiles of Prostate Cancer (PRISM-AI)

Prostate Cancer
University of Washington
National Institute of Allergy and Infectious Diseases (NIAID); Aurum Institute and other collaborators

Not yet recruiting

Periodic Presumptive Treatment vs. doxyPEP for STI Control in Kenyan MSM

Gonorrhea Male | Chlamydia (Male) | Syphilis Male
Region Skane
Horselvarden Region Ostergotland

Recruiting

Follow Up of an Online Hearing Support for First-time Hearing Aid Users

Hearing Loss | Hearing Disorders | Hearing Impairment

Sweden
Luye Pharma Group Ltd.

Recruiting

Phase II Clinical Trial to Evaluate the Efficacy and Safety of LPM3480392 Injection for Moderate to Severe Pain After Orthopedic Surgery

Pain, Postoperative

China
Guangdong Hengrui Pharmaceutical Co., Ltd

Not yet recruiting

Efficacy and Safety Study of SHR-1819 Injection in Adult Patients With Severe Atopic Dermatitis

Moderate to Severe Atopic Dermatitis

China
Dana-Farber Cancer Institute
National Cancer Institute (NCI); American Society of Clinical Oncology

Not yet recruiting

Driving Inclusivity, Validity, and Equity in Research Through Strategic Engagement (DIVERSE) (DIVERSE)

Leukemia | Blood Cancer

United States
University of Alcala

Recruiting

Radiofrequency and Myofascial Pain Syndrome in Postpartum Pelvic Pain (RASDOP)

To be Approved by the Ethics Committee

Spain
University of Minnesota

Recruiting

Identification of Prodromal Neurodegeneration in Serotonergic-Induced REM Sleep Behavior Disorder

Parkinson Disease | REM Sleep Behavior Disorder | Dementia With Lewy Bodies

United States
Steno Diabetes Center Copenhagen
Aarhus University Hospital

Recruiting

Automated Insulin Delivery for Type 1 Diabetes - Beyond Glucose Metrics (AID-BEYOND)

Diabetes Mellitus, Type 1

Denmark
Ruijin Hospital

Recruiting

A Trial on the Recurrence Free Survival Rate of Type I AIP With High-risk of Recurrence

Type 1 AIP

China
Duke University

Not yet recruiting

A Phase 1 Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of JCXH-211 (SElf-Replicating RNA IL-12) Intratumoral Injection in Patients With Recurrent or Progressive High-Grade Glioma (SERIL)

Recurrent or Progressive High-grade Glioma
Anhui Provincial Cancer Hospital

Recruiting

An Exploratory Clinical Study of Statins for Improving Chemotherapy and Maintenance in Patients With Ovarian Cancer

Ovarian Cancer

China
Ascidian Therapeutics, Inc

Recruiting

Study to Evaluate ACDN-01 in ABCA4-related Retinopathy (STELLAR) (STELLAR)

Stargardt Disease | Stargardt Disease 1 | Juvenile Macular Degeneration | Cone Rod Dystrophy

United States
Shanghai Zhongshan Hospital

Not yet recruiting

Appendicoliths in Acute Complicated Appendicitis Patients With Abscess

Acute Complicated Appendicitis With Abscess
Hacettepe University

Recruiting

Acute Effects of Three Different Types Single Leg Exercise in Copd (COPD)

Exercise

Turkey
Brigham and Women's Hospital
National Institute of General Medical Sciences (NIGMS)

Not yet recruiting

Understanding the Acute Pain Phenotype in Patients Undergoing Surgery

Acute Pain | Opioid Use | Chronic Post Operative Pain

United States
Ahram Canadian University

Recruiting

Inspiratory Muscle Training in Children With Beta Thalasemia

Beta Thalassemia Major

Egypt
University of Aarhus

Recruiting

Strategy for Withdrawal of Pharmacological Treatment for Urinary Incontinence in Children (StayDry)

Urinary Incontinence in Children

Denmark
Second Affiliated Hospital, School of Medicine,...
Huashan Hospital; The Affiliated Nanjing Drum Tower Hospital of Nanjing University... and other collaborators

Not yet recruiting

Tract-based Artificial Intelligence (AI) Robot Guiding System in Basal Ganglion Hemorrhage Evacuation

Basal Ganglia Hemorrhage

China
Radboud University Medical Center

Not yet recruiting

Methylphenidate in KBG Syndrome: N-of-1 Series (KBGS_N_of_1)

ADHD - Combined Type | Kbg Syndrome
Örebro University, Sweden
Region Örebro County

Not yet recruiting

Motion-based Interactive Technology for Improved Quality of Life in Individuals With Cognitive Impairment (WakeIT)

Cognitive Impairment | Dementia
Xuanwu Hospital, Beijing

Not yet recruiting

Correlation Analysis of POD and pNCD in Elderly Patients With Gastrointestinal Neoplasms Based on Rs-fMRI

Postoperative Delirium | Gastrointestinal Surgery | Postoperative Neurocognitive Disorder
AstraZeneca
ICON plc

Not yet recruiting

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis (MaesTTRo)

Transthyretin Amyloidosis | ATTR-CM | ATTRv-PN | ATTR | ATTR-Mixed | hATTR
Hospital of South West Jutland

Not yet recruiting

Non-pharmacological Treatment of Patients at Risk of Developing Persistent Posttraumatic Headache

Posttraumatic Headache
Shanghai Bovax Biotechnology Co., Ltd.

Not yet recruiting

A Phase III Study to Evaluate the Efficacy, Immunogenicity and Safety of the 9-valent HPV Vaccine in Chinese Males

Anal Cancer | HPV-Related Carcinoma | Penile Cancer | Genital Wart | AIN3 | AIN2 | PIN-1 | AIN1 | PIN2 | PIN3

China

Search clinical trials for: understudied diseases

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