Search clinical trials for: vector vaccine

Total 12064 results

International Vaccine Institute
Heidelberg University; International Centre for Diarrhoeal Disease Research... and other collaborators

Active, not recruiting

Mix and Match Heterologous Prime-Boost Study Using Approved COVID-19 Vaccines

Covid19

Madagascar, Mozambique
National Institute of Allergy and Infectious Diseases...

Completed

Trial to Evaluate CIS43LS in Healthy Adults

Malaria

United States
Seventh Medical Center of PLA General Hospital

Active, not recruiting

Evaluate the Safety and Immunogenicity of Ad5 COVID-19 Vaccines for Booster Use in Children Aged 6-17 Years.

COVID-19

China
Takeda

Completed

Study to Investigate the Safety and Immunogenicity of a Tetravalent Chimeric Dengue Vaccine in Healthy Volunteers Between the Ages of 1.5 - 45 Years

Healthy

Colombia, Singapore, Thailand, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

Phase I, Randomized, Double-blinded, Placebo-Controlled Dose De-escalation Study to Evaluate Safety and Immunogenicity of Alum Adjuvanted Zika Virus Purified Inactivated Vaccine (ZPIV) in Adults in a Flavivirus Endemic Area

Zika Virus Infection

Puerto Rico
Pfizer
Valneva Austria GmbH

Completed

Study Assessing the Safety, Immunogenicity and Dose Response of VLA15, A New Vaccine Candidate Against Lyme Borreliosis

Lyme Borreliosis, Nervous System

Belgium, United States
Radboud University Medical Center
The PATH Malaria Vaccine Initiative (MVI)

Completed

Safety, Tolerability, and Pharmacokinetics and Pharmacodynamics of TB31F (TB31F)

Malaria,Falciparum

Netherlands
National Institute of Allergy and Infectious Diseases...

Completed

Pfs230D1M-EPA/AS01 Vaccine, a Transmission Blocking Vaccine Against Plasmodium Falciparum, in an Age De-Escalation Trial of Children and a Family Compound Trial in Mali

Malaria

Mali
Ministry of Public Health, Argentina
Centers for Disease Control and Prevention; Pan American Health Organization

Enrolling by invitation

Immunogenicity of Yellow Fever Vaccine in a Pediatric Population Vaccinated at 12-23 Months of Age in Argentina

Yellow Fever

Argentina
Federal Budgetary Research Institution State Research...

Completed

Safety and Tolerability Study of the VAC∆6 Vaccine in Volunteers Aged 18-40 Years

Smallpox | Monkeypox | Cowpox | Vaccinia Virus Infection

Russian Federation
Vac4All

Active, not recruiting

MSP3-CRM-Vac4All/ Alhydrogel® Malaria Vaccine (MSP3CRMV4All)

Malaria,Falciparum

Mali
GlaxoSmithKline

Terminated

Safety, Tolerability and Pharmacokinetics (PKs) Investigation of GSK3186899 in Healthy Subjects

Leishmaniasis

United Kingdom
Valneva Austria GmbH

Active, not recruiting

Antibody Persistence And Long Term Safety Of A Chikungunya Virus Vaccine Candidate (VLA1553)

Chikungunya Virus Infection

United States
University of Oxford

Active, not recruiting

Safety and Immunogenicity of Pvs25-IMX313/Matrix-M1 Vaccine

Malaria, Vivax

United Kingdom
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity of a Tetravalent Dengue Vaccine in HIV-Positive Adults

Human Immunodeficiency Virus | Dengue Fever | Dengue Hemorrhagic Fever

Brazil
CanSino Biologics Inc.
Jiangsu Province Centers for Disease Control and Prevention; Beijing Institute...

Completed

Phase I/II Clinical Trial of Recombinant Novel Coronavirus (COVID-19) Vaccine (Adenovirus Type 5 Vector) for Inhalation

COVID-19

China
CanSino Biologics Inc.
Jiangsu Province Centers for Disease Control and Prevention

Completed

A Clinical Trial of Immunobridging and Lot-to-lot Consistency of COVID-19 Vaccine (Ad5-nCoV) in Different Age Groups.

COVID-19

China
University of Oxford
MRC/UVRI and LSHTM Uganda Research Unit

Completed

A Study to Assess the New Candidate Rift Valley Fever Virus Vaccine in Healthy Adults

Rift Valley Fever | RVF

Uganda
Biocad

Terminated

Clinical Study of the Safety and Immunogenicity of a Recombinant Viral Vector AAV5 (Adeno-Associated Virus Type 5 )-RBD (Receptor Binding Domain)-S Vaccine for the Prevention of Coronavirus Infection (COVID-19) (COVER)

COVID-19 | Coronavirus Infection

Russian Federation
GlaxoSmithKline
PATH; Iqvia Pty Ltd; AMP (Agence de Médecine Préventive) (in French); RAFT (Réseau... and other collaborators

Completed

A Surveillance Study of Diseases Specified as Adverse Events of Special Interest, of Other Adverse Events Leading to Hospitalisation or Death, and of Meningitis in Children in Africa Prior to Implementation of the RTS,S/AS01E Candidate Vaccine

Malaria | Malaria Vaccines

Ghana, Burkina Faso, Kenya
National Taiwan University Hospital
Centers for Disease Control, Taiwan

Completed

Clinical Trial of the Safety and Immunogenicity of a Tetravalent Dengue Virus Vaccine Admixture TV005 in the Elderly Aged 50-70 Years in Taiwan

Dengue

Taiwan
Pfizer

Completed

Immunogenicity and Safety Study of a Vaccine Against Lyme Borreliosis, in Healthy Adults Aged 18 to 65 Years. Randomized, Controlled, Observer-blind Phase 2 Study.

Lyme Borreliosis

United States, Germany, Belgium
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR); Samuel Lunenfeld Research Institute... and other collaborators

Active, not recruiting

SafeTy and Efficacy of Preventative CoVID Vaccines (STOPCoV)

Vaccine Response | COVID-19 Virus Infection

Canada
Sanofi Pasteur, a Sanofi Company

Active, not recruiting

Cohort Event Monitoring for Dengvaxia®, CYD-TDV Dengue Vaccine

Dengue Fever | Dengue Hemorrhagic Fever

Brazil, Mexico
Serge Thal

Completed

Effect of Different SARS-CoV-2 Vaccine Schedules and Vaccination Intervals on Reactogenicity and Humoral Immunogenicity

SARS-CoV2 Infection | Tolerance | Immunisation Reaction | Antibody Hypersensitivity

Germany
National Institute of Allergy and Infectious Diseases...
US Military HIV Research Program

Completed

Ebola Sudan Chimpanzee Adenovirus Vector Vaccine in Healthy Adults

Ebola Virus

Uganda
Emergex Vaccines Holding Ltd.
University of Lausanne Hospitals; Center for Primary Care and Public Health...

Completed

A Phase-I Study of a Nanoparticle-based Peptide Vaccine Against Dengue Virus

Dengue

Switzerland
Zhejiang Provincial Center for Disease Control...
Liaoning Chengda Biotechnology CO., LTD

Active, not recruiting

Seroprevalence of Neutralizing Antibodies Against Japanese Encephalitis Virus Among 6 Years Old Children With 5 Different Immunization Strategies in Zhejiang Province

Japanese Encephalitis | Vaccine Reaction | Vaccine Preventable Disease

China
CanSino Biologics Inc.
Jiangsu Province Centers for Disease Control and Prevention; Beijing Institute...

Completed

A Clinical Trial of A COVID-19 Vaccine Named Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector)

COVID-19

China
R-Pharm
AstraZeneca

Completed

Safety and Immunogenicity Study in Adults of AZD1222 and rAd26-S Administered as Heterologous Prime Boost Regimen for the Prevention of Coronavirus Disease 2019 (COVID-19)

COVID-19

United Arab Emirates
National Taiwan University Hospital
Taoyuan General Hospital, Ministry of Health and Welfare,Taoyuan,Taiwan

Completed

Efficacy and Safety of Heterologous and Homologous COVID-19 Vaccination

Healthy Adult Volunteers

Taiwan
Vaxart
Biomedical Advanced Research and Development Authority

Completed

A Phase 2 Influenza A Challenge Study Following Oral Administration of an H1N1 HA Ad-Vector Seasonal Flu Vaccine

Influenza

United States
University of York
Wellcome Trust; European and Developing Countries Clinical Trials Partnership... and other collaborators

Withdrawn

A Study to Assess Safety and Efficacy of a Leishmania Vaccine to Prevent Post Kala Azar Dermal Leishmaniasis (PKDL) (LEISH3)

Post-kala-azar Dermal Leishmaniasis
Vaxart

Completed

A Phase 1, Open-label, Safety and Immunogenicity Study of an Oral Multi-dose Administration Regimen With an Adenoviral-vector Based Tablet Norovirus Vaccine (VXA-G1.1-NN) Administered to Healthy Adult Volunteers ((VXA-G1-1-NN))

Norovirus Infections

United States
PATH
GlaxoSmithKline; Kenya Medical Research Institute; US Army Medical Research Directorate-Africa... and other collaborators

Completed

RTS,S/AS01E Hypo-immuno-responsiveness Study

Plasmodium Falciparum

Kenya
Themis Bioscience GmbH
Walter Reed Army Institute of Research (WRAIR)

Completed

Chikungunya Vaccine (V184) Study in Previously Exposed Adults (V184-006)

Chikungunya Virus Infection

Puerto Rico
Takeda

Completed

Immunogenicity and Safety of Tetravalent Dengue Vaccine (TDV) Co-administered With an Hepatitis A Virus Vaccine

Healthy Volunteers

United Kingdom
Themis Bioscience GmbH

Completed

Zika-Vaccine Dose Finding Study Regarding Safety, Immunogenicity and Tolerability (V186-001)

Zika Virus

Austria
Jiangsu Province Centers for Disease Control and...

Active, not recruiting

Heterologous Prime-boost Immunization With an Aerosolised Adenovirus Type-5 Vector-based COVID-19 Vaccine (Ad5-nCoV) After Priming With an Inactivated SARS-CoV-2 Vaccine

COVID-19

China
Jiangsu Province Centers for Disease Control and...
CanSino Biologics Inc.

Completed

Study on Sequential Immunization of Inactivated COVID-19 Vaccine and Recombinant COVID-19 Vaccine (Ad5 Vector) in Elderly Adults

COVID-19

China
Albert B. Sabin Vaccine Institute
ICON plc; Oklahoma Blood Institute

Completed

Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults

Ebola Virus Disease | Marburg Virus Disease

United States
Sanaria Inc.
Fred Hutchinson Cancer Center

Completed

Safety, Tolerability and Efficacy of PfSPZ Vaccine Against Heterologous CHMI in US Malaria naïve Adults

Malaria

United States
Janssen Vaccines & Prevention B.V.
London School of Hygiene and Tropical Medicine; Institut National de la Santé... and other collaborators

Completed

Staged Phase 3 Study to Assess the Safety and Immunogenicity of Ebola Candidate Vaccines Ad26.ZEBOV and MVA-BN-Filo (EBOVAC-Salone)

Ebola Virus Disease

Sierra Leone
National Institute of Allergy and Infectious Diseases...

Completed

Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcipa...

Malaria

Mali
Radboud University Medical Center
Novavax; Statens Serum Institut

Completed

Safety and Efficacy of R0.6C Vaccine (STOP-TRANS)

Malaria | Malaria,Falciparum

Netherlands
R-Pharm
AstraZeneca; Russian Direct Investment Fund; The Gamaleya National Center of...

Completed

Open-label, Non-randomized, Non-comparative, Phase II Study of Safety and Immunogenicity of Combination of AZD1222 and rAd26-S for COVID-19 Prevention

COVID-19

Azerbaijan
National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of the Safety and Immunogenicity of the Live Attenuated Zika Vaccine rZIKV/D4Δ30-713 in Flavivirus-naïve Adults

Zika Virus

United States
Jiangsu Province Centers for Disease Control and...
Hunan Provincial Center for Disease Control and Prevention; Yunnan Center for... and other collaborators

Active, not recruiting

Heterologous Boost Immunization With an Aerosolised Ad5-nCoV After Two-dose Priming With an Inactivated SARS-CoV-2 Vaccine

COVID-19

China
National Institute of Allergy and Infectious Diseases...
PepTcell Limited (t/a SEEK)

Completed

Evaluating the Safety and Immunogenicity of AGS-v PLUS, a Universal Mosquito-Borne Disease and Mosquito Control Vaccine

Mosquito-Borne Infectious Diseases

United States
Sanofi Pasteur, a Sanofi Company

Completed

Postmarketing Surveillance Study for IMOJEV® in Republic of Korea

Japanese Encephalitis

Korea, Republic of

Search clinical trials for: vector vaccine

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