Clinical Trials Sponsored by Tourmaline Bio, Inc.

Total 364 results

BioQ Pharma, Inc.
Health Decisions

Completed

Ropivacaine 0.2% Pre-Filled Dispenser for the Treatment of Postsurgical Pain in Patients Undergoing Cesarean Delivery

Pain, Postoperative

United States
Tempero Bio, Inc.
National Institute on Drug Abuse (NIDA)

Completed

Multiple Ascending Dose Study of TMP-301 in Healthy Subjects

Healthy Volunteers | Substance Use Disorders | Cocaine Use Disorder

United States
University of Utah
Bristol-Myers Squibb; Takara Bio Inc.

Terminated

Neoadjuvant Trial of Nivolumab in Combination With HF10 Oncolytic Viral Therapy in Resectable Stage IIIB, IIIC, IVM1a Melanoma

Melanoma

United States
Bio-K Plus International Inc.
Sprim Advanced Life Sciences

Completed

Effect of BIO-K+ on Symptoms of Irritable Bowel Syndrome

Irritable Bowel Syndrome

United States
Bio-K Plus International Inc.
Sprim Advanced Life Sciences

Completed

Efficacy and Safety Study in the Prevention of Antibiotic-Associated Diarrhea (AAD) and Clostridium Difficile-Associated Diarrhea (CDAD) in Hospitalized Adult Patients Exposed to Nosocomial Infection

Clostridium Difficile-Associated Diarrhea | Antibiotic-Associated Diarrhea
University of Illinois at Urbana-Champaign
BIO-CAT, Inc.

Completed

Effect of Microbial Protease Supplementation on Postprandial Amino Acid Levels

Protein Metabolism

United States
Scripps Translational Science Institute
Scripps Health; Lexent Bio, Inc.

Unknown

Recurrence Monitoring in NSCLC Using Circulating Tumor DNA

Non Small Cell Lung Cancer

United States
St. Renatus, LLC
Rho, Inc.; Triligent International; Analytical Bio-Chemistry Laboratories, Inc.

Completed

Safety and Pharmacokinetics of Kovacaine Nasal Spray in Pediatric Subjects

Anesthesia

United States
Glenn J. Hanna
Secura Bio, Inc.

Active, not recruiting

Duvelisib Plus Docetaxel In Recurrent/Metastatic HNSCC

Metastatic Head and Neck Cancer | Advanced Head and Neck Squamous Cell Carcinoma | Recurrent Squamous Cell Carcinoma of the Head and Neck | Squamous Cell Carcinoma of the Head and Neck (SCCHN) | Advanced Head and Neck Cancer

United States
Shanghai JMT-Bio Inc.
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Unknown

Efficacy and Safety of JMT101 Combined With Afatinib (or Osimertinib) in Patients With Non-Small Cell Lung Cancer

Locally Advanced or Metastatic Non-Small Cell Lung Cancer

China
Bird Rock Bio, Inc.
Techtrials Pesquisa e Tecnologia Ltda; Pharmagenix

Withdrawn

Study Evaluating Gerilimzumab´s Safety/Efficacy for Patients MTX or TNFα Antagonist Failed in Rheumatoid Arthritis

Rheumatoid Arthritis
Brain Neurotherapy Bio, Inc.
California Institute for Regenerative Medicine (CIRM); Asklepios Biopharmaceutical...

Active, not recruiting

GDNF Gene Therapy for Parkinson's Disease

Parkinson's Disease

United States
Shanghai JMT-Bio Inc.
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Not yet recruiting

Efficacy and Safety of JMT101 Combined With Osimertinib in Patients With Non-Small Cell Lung Cancer

Locally Advanced or Metastatic Non-Small Cell Lung Cancer | EGFR Exon20 Insertion Mutations
Emory University
National Cancer Institute (NCI); Novartis; Secura Bio, Inc.

Recruiting

Duvelisib Exposure to Enhance Immune Profiles of T Cells in Patients With Recurrent or Refractory Diffuse Large B-Cell Lymphoma, DEEP T CELLS Study

Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma

United States
Shanghai JMT-Bio Inc.
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Unknown

Efficacy and Safety of JMT101 in Patients With Advanced Solid Tumor

Advanced Solid Tumor

China
Shanghai JMT-Bio Inc.
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Unknown

A Clinical Trial to Assess the Efficacy and Safety of JMT103 in Patients With Refractory HCM

Hypercalcemia of Malignancy
Shanghai JMT-Bio Inc.
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Not yet recruiting

Real-World Effectiveness of Osimertinib for Patients With Non-Small Cell Lung Cancer

Locally Advanced or Metastatic Non-Small Cell Lung Cancer | EGFR Exon20 Insertion Mutations

China
Bio-K Plus International Inc.
Centre Hospitalier Pierre-Le Gardeur

Withdrawn

Evaluation of the Efficacy of Bio-K+ Cl-1285® In the Nasal Decolonization of Methicillin Resistant Staphylococcus Aureus (MRSA) Carrier Patients (MRSA)

MRSA Colonization

Canada
University of Oxford
Big Health Inc.

Recruiting

Improving Sleep and Learning in Rehabilitation After Stroke, Part 2 (INSPIRES-2)

Stroke

United Kingdom
KBio Inc
Eastern Virginia Medical School

Completed

An Exploratory Study of ZB-06 as a Vaginal Contraceptive Film

Contraception

United States
BIO-CAT Microbials, LLC
Ohio State University; Biofortis Clinical Research, Inc.

Completed

The Effects of a Novel Probiotic on Gastrointestinal Health in Generally Healthy Adults

Immune Health | Gastrointestinal Health | Digestive Health

United States
Shanghai Bio-heart Biological Technology Co., Ltd.
CCRF Inc., Beijing, China

Active, not recruiting

Bioheart Rapamycin Drug-Eluting Bioresorbable Coronary Stent System Clinical Study

Coronary Artery Disease | Antineoplastic Agents

China
Treadwell Therapeutics, Inc
TIO Discovery Engine

Recruiting

Safety and Efficacy Study of CFI-402411 in Subjects With Advanced Solid Malignancies

Advanced Solid Malignancies

United States, Hong Kong, Canada
University of Oxford
Big Health Inc.

Active, not recruiting

Improving Sleep in Rehabilitation After Stroke (INSPIRES)

Stroke

United Kingdom
John Kirkwood
Bristol-Myers Squibb; Secura Bio, Inc.

Recruiting

Duvelisib in Combination With Nivolumab in Patients With Advanced Unresectable Melanoma

Unresectable Melanoma

United States
Shanghai Bio-heart Biological Technology Co., Ltd.
CCRF Inc., Beijing, China

Not yet recruiting

A Registry Trial of The Bioheart Rapamycin Drug-Eluting Bioresorbable Coronary Stent System

Coronary Artery Disease

China
AmeriSciences LP
Bio-Medical Consultants, Inc.; Vantage Data Solutions Inc.; Esoterix, Inc.; Dr....

Terminated

Toxicity and Safety Evaluation of an Omega-3 Fatty Acid and a Multivitamin and Antioxidant Nutritional Preparation

Healthy

United States
National Institute of Allergy and Infectious Diseases...
Gritstone bio, Inc.

Completed

Chimpanzee Adenovirus and Self-Amplifying mRNA Prime-Boost Prophylactic Vaccines Against SARS-CoV-2 in Healthy Adults

COVID-19

United States
H. Lee Moffitt Cancer Center and Research Institute
Secura Bio, Inc.

Active, not recruiting

Duvelisib in Combination With BMS-986345 in Lymphoid Malignancy

Hodgkin Lymphoma | Non Hodgkin Lymphoma | Myeloma | Lymphocytic Leukemia

United States
Kanyos Bio, Inc., a wholly-owned subsidiary of...

Completed

Assessment of KAN-101 in Celiac Disease (ACeD)

Celiac Disease

United States
Bio-K Plus International Inc.
Centre hospitalier de l'Université de Montréal (CHUM)

Terminated

Study of Bio-K+® in the Reduction of the Risk of Clostridium Difficile Infection and Antibiotic Associated Diarrhea

Clostridium Difficile Infection | Antibiotic Associated Diarrhea

Canada
Mie University
Fiverings Co., Ltd.; Shionogi; Takara Bio Inc.; Statcom Co. Ltd.

Completed

Investigator Initiated Phase 1 Study of TBI-1201

Solid Tumors

Japan
Jichi Medical University
Takara Bio Inc.; Gene Therapy Research Institution,Co.,Ltd.

Terminated

AADC Gene Therapy for Parkinson's Disease

Parkinson Disease

Japan
Mie University
Fiverings Co., Ltd.; Shionogi; Takara Bio Inc.; Statcom Co. Ltd.

Unknown

Investigator Initiated Phase 1 Study of TBI-1301

Solid Tumors

Japan
Xequel Bio, Inc.
Medical University of South Carolina; Spartanburg Regional Healthcare System

Completed

Safety Study to Examine the Systemic Exposure of Granexin® Gel After Topical Application to Diabetic Foot Ulcers

Diabetic Foot Ulcers

United States
City of Hope Medical Center
National Cancer Institute (NCI); Mustang Bio, Inc.

Active, not recruiting

Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm

Acute Myeloid Leukemia | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in Remission | Refractory Acute Myeloid Leukemia | Blastic Plasmacytoid Dendritic Cell Neoplasm | Minimal Residual Disease | Acute... and other conditions

United States
Xequel Bio, Inc.
Medical University of South Carolina; Spartanburg Regional Healthcare System

Completed

Safety Study to Examine the Systemic Exposure of Granexin® Gel After Topical Application to Venous Leg Ulcers

Venous Leg Ulcer

United States
Leigh Eck, MD
Bio-Tech Pharmacal, Inc.

Completed

Impact of Vitamin D Supplementation on Lactation Associated Bone Loss

Osteoporosis

United States
Kanyos Bio, Inc., a wholly-owned subsidiary of...
Pfizer

Recruiting

A Study of Efficacy, Safety, and Tolerability of KAN-101 in People With Celiac Disease (SynCeD)

Celiac Disease | Coeliac Disease

United States, Canada, Poland, Germany
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.; Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of GNC-038 Injection in Patients With Relapsed or Refractory NK/ T-cell Lymphoma, AITL, and Other NHL

Non-Hodgkin Lymphoma | NK/T Cell Lymphoma | Vascular Immunomother T Cell Lymphoma

China
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.; Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

Phase Ib/II Study of GNC-038 Injection in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Non-hodgkin's Lymphoma

China
Kanyos Bio, Inc., a wholly-owned subsidiary of...
Pfizer

Recruiting

A Study of Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of KAN-101 in Celiac Disease (ACeD-it)

Celiac Disease

United States, Australia, New Zealand
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.; Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of GNC-038, a Tetra-specific Antibody, in Patients With Central Nervous System Lymphoma (PCNSL) and Relapsed or Refractory Secondary Central Nervous System Lymphoma (SCNSL)

Primary Central Nervous System Lymphoma | Secondary Central Nervous System Lymphoma

China
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.; Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of BL-M07D1 in Patients With Locally Advanced or Metastatic HER2 Positive/Low Expression Breast Cancer and Other Solid Tumors

Breast Cancer | Locally Advanced or Metastatic Solid Tumor

China
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.; Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of BL-M02D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors or Other Solid Tumors

Solid Tumor | Locally Advanced or Metastatic Digestive Tract Tumors

China
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.; Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of BL-M02D1 in Patients With Locally Advanced or Metastatic Triple Negative Breast Cancer or Other Solid Tumors

Breast Cancer

China
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.; Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumor and Other Solid Tumor

Gastrointestinal Tumor

China
Hebrew SeniorLife
Beth Israel Deaconess Medical Center; Tufts University; MaineHealth; Solarea Bio...

Not yet recruiting

Synbiotic to Attenuate Resorption of the Skeleton (STARS)

Inflammation | Aging | Osteoporosis

United States
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.; Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

Phase I Clinical Study of BL-M07D1 in Locally Advanced or Metastatic Digestive Tract Tumors and Other Solid Tumors

Other Solid Tumors | Locally Advanced or Metastatic Digestive Tract Tumors

China
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.; Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of BL-B01D1 in Patients With Unresectable Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors

Breast Cancer | Solid Tumor

China

Clinical Trials Sponsored by Tourmaline Bio, Inc.

Sponsors and Collaborators

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CROs in Albania

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