Search clinical trials for: Anti-PCSK9

Total 96955 results

Hospices Civils de Lyon

Completed

Impact of a Procedure for the Information and Active Participation of the Patient in the Primary Care Prescription of Antihypertensives (InPAct)

Patients on Anti-hypertensive Medication

France
Massachusetts General Hospital
GlaxoSmithKline

Terminated

Significance of Antibodies to Heparin/Platelet Factor 4 Complex in Vein Graft Patency and Potential Role of Argatroban for Prevention of Vein Graft Occlusion

Coronary Artery Bypass Graft Surgery | Presence of Heparin/Platelet Factor 4 Antibody

United States
Baxalta now part of Shire

Completed

Phase 1 Study of Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody in Solid Tumors

Malignant Solid Tumors | Metastatic Adenocarcinoma of the Colon or Rectum

Germany, United States
Chang Gung Memorial Hospital
Chang Gung University

Recruiting

Trial of PCSK9 Inhibition in Patients With Acute Stroke and Symptomatic Intracranial Atherosclerosis (TOPICAL-MRI)

Acute Ischemic Stroke | Intracranial Atherosclerosis | ICAS - Intracranial Atherosclerosis

Taiwan
Collegium Medicum w Bydgoszczy

Completed

Impact of PCSK9 Inhibition on Clinical Outcome in Patients During the Inflammatory Stage of the COVID-19 (IMPACT-SIRIO 5)

Sars-CoV-2 Infection

Poland
Third Military Medical University

Recruiting

Risk of NSAIDs on Anastomotic Leak for Rectal Surgery

Anastomotic Leak | Anti-Inflammatory Agents, Non-Steroidal

China
Sun Yat-sen University

Completed

The Molecular Mechanism of RAS Wild-type mCRC Resistance to Anti-EGFR-antibody

Colorectal Cancer

China
Academisch Medisch Centrum - Universiteit van Amsterdam...

Unknown

Mechanism of Action of Ustekinumab in Psoriatic Arthritis (MoA anti-p40)

Arthritis, Psoriatic

Netherlands
King Chulalongkorn Memorial Hospital

Completed

Cytoprotective Agent and Peptic Ulcer in Dual Antiplatelet :RCT

Gastric Ulcer Induced by Anti-platelet Agent | Duodenal Ulcer Induced by Anti-platelet Agent

Thailand
Augenabteilung Allgemeines Krankenhaus Linz

Completed

Effect Aflibercept on Ocular Perfusion

Macular Degeneration | Anti Vascular Endothelial Growth Factor

Austria
Akeso
AD Pharmaceuticals Co., Ltd.

Completed

A Study of PCSK9 Inhibitor AK102 in Patients With Hypercholesterolemia

Hypercholesterolemia

China
Nantes University Hospital
Centre de Recherche en Nutrition Humaine Ouest (CRNH)

Completed

Kinetic Study of Lp(a) and PCSK9 in Humans (HuLaUP)

Cholesterol; Metabolic Disorder | Lipoproteinemia

France
Alliancells-PuRui Biocience Co., Ltd.
Zhongyuan Union Stem Cell Bio-engineering Corporation

Unknown

Safety Study of Cord Blood-derived Cytokine-induced Killer Cells in Patients With Solid Tumor After Radical Resection

Renal Cell Carcinoma | Hepatocellular Carcinoma | Lung Cancer

China
Osaka University

Completed

Randomized Trial for Pharmacogenomics-based Tuberculosis Therapy (RT-PGTT)

Pulmonary Tuberculosis

Japan
Amgen
TIMI Study Group

Completed

LAPLACE-TIMI 57: Low-density Lipoprotein Cholesterol (LDL-C) Assessment With PCSK9 monoclonaL Antibody Inhibition Combined With Statin thErapy (LAPLACE)

Hyperlipidemia

United States, Canada, Denmark, Czechia, Hungary
Fudan University
Chinese Anti-Cancer Association

Completed

Minus Anthracycline or Short-Term Versus Epirubicin and Cyclophosphamide Followed by Paclitaxel Regimen for Adjuvant Breast Cancer Therapy

Primary Breast Cancer

China
Lund University
Anti-Diabetic Food Centre

Completed

Effects on Cognitive Functions and Mood of Food Products Rich in Polyphenols

Mood | Cognitive Performance | Cardiometabolic Risk Markers

Sweden
Lund University
Anti-Diabetic Food Centre

Completed

Effects on Metabolism and Cognitive Functions of a Commonly Used Commercial Food Supplement

Postprandial Blood Glucose Regulation

Sweden
Lund University
Anti-Diabetic Food Centre

Completed

Effect of a Synergistic Food Basket on Metabolic Syndrome Risk

Metabolic Syndrome | Insulin Resistance

Sweden
Lund University
Anti-Diabetic Food Centre

Completed

Effects of Berries and Vegetables on Cardiometabolic Risk Markers and Cognitive Functions

Inflammation | Metabolic Syndrome | Aging | Fermentation

Sweden
Fudan University
Chinese Anti-Cancer Association

Available

Efficacy and Safety Study of Neoadjuvant Chemotherapy for Local Advanced Triple Negative Breast Cancer Patients

Triple Negative Local Advanced Breast Cancer
VA Office of Research and Development
University of Wisconsin, Madison

Completed

Impact of Probiotics for Reducing Infections in Veterans: The IMPROVE Study

Anti-biotic Resistance

United States
Amgen

Completed

Durable Effect of PCSK9 Antibody CompARed wiTh placEbo Study (DESCARTES)

Hypercholesterolemia

United States, Denmark, Belgium, Czechia, Austria, Australia, Canada, Hungary, South Africa
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-C203: Phase II Randomized (Patients Are Assigned Different Treatments Based on Chance), Placebo Controlled Dose Escalating Trial of TMC125 in HIV-1 Infected Patients

HIV-1 | Anti-Retroviral Agents
Haisco Pharmaceutical Group Co., Ltd.
The First Affiliated Hospital of Soochow University

Completed

Pharmacokinetics, Mass Balance, and Metabolism of [14C]HSK21542 in Healthy Adult Male Volunteers.

Peripheral Analgesic and Anti-itch

China
Robert Rosenson
University of Michigan; University of Toronto; Amgen

Completed

The Effects of Evolocumab in Patients With Diabetes and Atherosclerotic Vascular Disease

Type2 Diabetes | Microvascular Dysfunction | Atherosclerotic Vascular Disease

United States, Canada
Assistance Publique - Hôpitaux de Paris

Recruiting

Register of Patients With Anti-Phospholipids Syndrome (APS) and/or Systemic Lupus Erythematosus (SLE) (SAPL-LUPUS)

Anti-Phospholipids Syndrome (APS) | Systemic Lupus Erythematosus (SLE)

France
Dacima Consulting
Ligue Tunisienne Anti Rhumatismale

Completed

Biologic National Registry (BINAR)

Arthritis, Rheumatoid | Spondylitis

Tunisia
Fudan University
Chinese Anti-Cancer Association

Completed

Adjuvant Platinum and Taxane in Triple-negative Breast Cancer (PATTERN)

Triple Negative Breast Cancer
Lund University
Anti-Diabetic Food Centre

Completed

Effect of Herbs and Spices on Metabolic Regulation and Appetite in Healthy Subjects (AFC-SPICES)

Healthy

Sweden
Lund University
Anti-Diabetic Food Centre

Completed

Postprandial Effects of Mixed Herbs and Spices on Pathways Associated With Glucose Homeostasis and Inflammation on PBMCs of Healthy Subjects

Healthy

Sweden
Lund University
Anti-Diabetic Food Centre

Completed

On the Impact of Common Sweetening Agents on Glucose Regulation, Cognitive Functioning and Gut Microbiota

Healthy Subjects

Sweden
Lund University
Anti-Diabetic Food Centre

Completed

Effects of Legumes on Glucose Regulation

Dietary Prevention

Sweden
Peking Union Medical College Hospital

Recruiting

Telitacicept in Primary APS Patients

Anti Phospholipid Syndrome

China
Boston University
Bill and Melinda Gates Foundation; University of Witwatersrand, South Africa; Clinton Health Access Initiative Inc...

Active, not recruiting

Survey of Procedures and Resources for Initiating Treatment of HIV in Africa-Malawi (SPRINT-Malawi)

HIV | Antiretroviral Therapy

Malawi, South Africa
Dallas VA Medical Center

Completed

Safety of Continuing Anti-platelet Agents During Colonoscopic Polypectomy: A Prospective Study

Colonoscopy | Post-polypectomy Bleeding | Anti-platelet Therapy

United States
Mount Sinai Hospital, Canada
The Physicians' Services Incorporated Foundation

Unknown

Efficacy Study Comparing 2% Chlorhexidine in 70% Isopropyl Alcohol Versus 2% Aqueous Chlorhexidine

Anti-infecting Agents, Local

Canada
The University of Hong Kong

Terminated

Effect of Second-look Endoscopy on Peptic Ulcer Rebleeding in Patients With Early Resumption of Antiplatelet Agents

Gastric Ulcer Induced by Anti-platelet Agent | Duodenal Ulcer Induced by Anti-platelet Agent | OGD

China, Hong Kong
Boston University
Bill and Melinda Gates Foundation; University of Witwatersrand, South Africa

Active, not recruiting

Survey of Procedures and Resources for Initiating Treatment of HIV in Africa-South Africa (SPRINT-SA)

HIV | Antiretroviral Therapy

South Africa
Instituto Valenciano de Infertilidad, IVI VALENCIA

Completed

Impact of Gonadotrophin REceptor Polimorphisms on the Relationship Between Serum AMH and Ovarian Response (GREPAMOR)

antimüllerian Hormone and Gonadotrophin Receptor Polymorphism as Predictors of Ovarian Response

Spain
TCI Co., Ltd.

Completed

Investigation of the Efficacies of Multi Berries Juice on Anti Oxidant Effect and Improvement of Skin Conditions

Skin Condition | Anti Oxidative Stress

Taiwan
Medicalps
Icadom; AG2R La Mondiale; AVALUN; ORIADE NOVIALE; SIL-LAB INNOVATIONS; TASDA

Completed

INR at Home Measurement by the LabPad® Point-of-care in Patients on Vitamin K Antagonist Drugs (VKA) (INRADOM)

Vitamine K Antagonist (VKA) Treatment | International Normalized Ratio (INR) Measure at Home | Thromboembolic Pathology

France
Medical University of Graz

Completed

The Effect of Antihypertensive Drugs on Severity of Anaphylaxis and Side-effects During Venom Immunotherapy (EADOAS)

Hymenoptera Venom Allergy | Antihypertensive Treatment

Austria
Haitian Group for the Study of Kaposi's Sarcoma...
Harvard Medical School (HMS and HSDM); Brigham and Women's Hospital; Weill Medical... and other collaborators

Unknown

Continuation of Protease-Inhibitor Based Second-Line Therapy vs. Switch to B/F/TAF in Virologically Suppressed Adults

Antiretroviral Therapy | HIV-1-infection

Haiti
Kanuni Sultan Suleyman Training and Research Hospital

Completed

Ovarian Reserve in Patients With Psoriasis

Psoriasis | Ovarian Reserve | Anti Mullerian Hormone

Turkey
Amgen

Completed

A Study in Healthy Volunteers to Evaluate the Pharmacokinetic Food Effect and Cardiac Safety of CCX168

Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis

United States
Stony Brook University
The Plastic Surgery Foundation

Completed

Postoperative Antibiotic Requirements Following Immediate Breast Reconstruction

Breast Implantation | Bacterial Infection | Anti-infective Agents

United States
Gloria Vega
Regeneron Pharmaceuticals; Aventis Pharmaceuticals

Terminated

Effect of PCSK9-Antibody (Alirocumab) on Dyslipidemia Secondary to Nephrotic Syndrome

Nephrotic Syndrome

United States
Yi Feng, MD

Unknown

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Intravenous Ibuprofen 400 and 800 mg Every 6 Hours in the Management of Postoperative Pain.

Pain | Ibuprofen | Nonsteroidal Anti-inflammatory Drug | Intravenous | Injectable | Analgesic

China
Fundació Institut Germans Trias i Pujol

Completed

Influence of the Vitreomacular Interface on the Progression of the Diabetic Macular Edema After Anti-VEGF Injection

Diabetic Macular Edema | Vitreomacular Interface | Anti-VEGF Treatment

Search clinical trials for: Anti-PCSK9

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