Search clinical trials for: Antiretroviral Therapy

Total 54680 results

Kirby Institute
National Health and Medical Research Council, Australia; National Institute... and other collaborators

Active, not recruiting

Dolutegravir and Darunavir Evaluation in Adults Failing Therapy (D²EFT)

HIV Infections

Mexico, Thailand, Malaysia, Argentina, Brazil, India, Nigeria, South Africa, Chile, Colombia, Guinea, Indonesia, Mali, Zimbabwe
Elizabeth Glaser Pediatric AIDS Foundation
Janssen, LP

Active, not recruiting

Characteristics and Outcomes of Patients Who Received Etravirine and/or Darunavir (NewHorizon)

HIV/AIDS

Cameroon, Kenya, Lesotho, Swaziland, Uganda
Eiger BioPharmaceuticals

Completed

Study of the Efficacy and Safety of Lonafarnib / Ritonavir With and Without Pegylated Interferon -Alfa-2a (D-LIVR)

Hepatitis Delta Virus

United States, Belgium, Spain, Greece, Canada, Italy, Romania, Germany, Israel, Bulgaria, Taiwan, Turkey, Pakistan, Sweden, Ukraine, New Zealand, Russian Federation, United Kingdom, Moldova, Republic of, France, Mongolia, Switzerland
ViiV Healthcare

Completed

Study to Identify and Determine Best Implementation Practices for Injectable Cabotegravir+Rilpivirine in the United States (US)

HIV Infections

United States
ViiV Healthcare
Janssen, LP

Completed

Phase 2b, Open-label, Multicenter, Rollover Study to Assess Antiviral Activity and Safety of Long-acting (LA) Cabotegravir (CAB) Plus LA Rilpivirine (RPV), Administered Every 2 Months (Q2M), in Human Immunodeficiency Virus (HIV)-Positive Participants From the LATTE Study

HIV Infections

United States, Canada
American Gene Technologies International Inc.

Completed

Study to Evaluate the Safety of a Gene and Cell Therapy Product in Participants With HIV That is Well-Controlled on Antiretroviral Therapy

HIV

United States
E-DA Hospital

Active, not recruiting

Finite Versus Continuous Nucleos(t)Ide Analogues for Chronic Hepatitis B

Chronic Hepatitis b

Taiwan
Moritz Oberndorfer
Merck Gesellschaft mbH, Austria

Completed

Lipid Profile and Diabetes Mellitus in People With HIV

HIV Infections | Diabetes Mellitus | Dyslipidemias | Cardiovascular Risk Factor

Austria
PENTA Foundation

Active, not recruiting

Early Anti-Retroviral Treatment in HIV- Infected Children

HIV Infections

South Africa, Mali, Mozambique
Makerere University

Completed

Safety and Efficacy of High Dose Rifampicin in Tuberculosis (TB)-HIV Co-infected Patients on Efavirenz- or Dolutegravir-based Antiretroviral Therapy (SAEFRIF)

Tuberculosis

Uganda
Massachusetts General Hospital
National Institute of Allergy and Infectious Diseases (NIAID); Emory University and other collaborators

Completed

Resistance Testing to Improve Management of Virologic Failure in Sub-Saharan Africa (REVAMP)

HIV | AIDS

Uganda, South Africa
Catherine Anne Chappell
University of Nebraska; Infectious Disease Institute, Kampala, Uganda

Completed

Pharmacologic Strategies for the Etonogestrel Implant in HIV-Infected Women

HIV/AIDS | Contraception

Uganda
ViiV Healthcare
GlaxoSmithKline

Completed

Comparative Efficacy and Safety Study of Dolutegravir and Lopinavir/Ritonavir in Second-line Treatment

HIV Infections

Argentina, Thailand, Russian Federation, Mexico, South Africa, Romania, China, Chile, Ukraine, Colombia, Peru, Brazil, Kenya
Thai Red Cross AIDS Research Centre

Active, not recruiting

Differentiated Service Delivery for Antiretroviral Therapy

HIV Infections

Thailand
Thai Red Cross AIDS Research Centre

Active, not recruiting

Same-Day Antiretroviral Therapy Initiation

HIV Infections

Thailand
Celularity Incorporated

Active, not recruiting

CYNK-101 in Combination With Trastuzumab and Pembrolizumab in Patients With Locally Advanced Unresectable or Metastatic HER2-Positive Gastric or Gastroesophageal Junction (G/GEJ) Adenocarcinoma

Metastatic HER2 Positive Gastroesophageal Junction Cancer

United States
Carman Giacomantonio
Nova Scotia Health Authority

Withdrawn

The Response to Intralesional IL-2 and/or BCG Treatment for Cutaneous Metastatic Melanoma

Cutaneous Metastatic Melanoma
Association de Recherche en Virologie et Dermatologie
ViiV Healthcare

Completed

Dynamics of Drug Resistance-associated Mutations in HIV-1 DNA Reverse Transcriptase Clearance During Effective Antiretroviral Therapy (MUTARESERVOIR)

HIV-1-infection

France
Professor Francois Venter

Completed

ADVANCE Study of DTG + TAF + FTC vs DTG + TDF + FTC and EFV + TDF+FTC in First-line Antiretroviral Therapy (ADVANCE)

HIV-1 Infection

South Africa
French National Agency for Research on AIDS and...
Gilead Sciences; Pharmasset

Terminated

ANRS HB 05 Multicenter Study Evaluating Efficacy and Safety of Clevudine Monotherapy Versus Tenofovir Monotherapy Versus Combination Therapy of Clevudine and Tenofovir for 96 Weeks in HBeAg Negative Patients With Chronic Hepatitis B, naïve to Anti-VHB Therapy

HBe Negative Chronic Hepatitis B | Hepatitis B Viral Infection

France
Dana-Farber Cancer Institute
Massachusetts General Hospital; Beth Israel Deaconess Medical Center

Terminated

CHOEP + High Dose Therapy + Auto SCT for T-Cell Lymphoma

T-cell Non-Hodgkin Lymphoma

United States
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb; Iovance Biotherapeutics, Inc.; Prometheus Inc.

Completed

Combining PD-1 Blockade, CD137 Agonism and Adoptive Cell Therapy for Metastatic Melanoma

Skin Cancer | Melanoma (Skin)

United States
National Cancer Institute (NCI)

Completed

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Melanoma

Metastatic Melanoma

United States
Karolinska University Hospital
Karolinska Institutet; University of Witten/Herdecke; Ekhagastiftelsen; Regional... and other collaborators

Completed

Mistletoe Therapy in Primary and Recurrent Inoperable Pancreatic Cancer (MISTRAL)

Pancreatic Cancer

Sweden
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

An Integrated Strategy to Support Antiretroviral Therapy and Pre-exposure Prophylaxis Adherence for HIV Prevention in Pregnant and Breastfeeding Women

HIV-1-infection | Antenatal Care

Malawi
University of California, San Diego
National Institute of Mental Health (NIMH); GlaxoSmithKline; Gilead Sciences; ViiV... and other collaborators

Active, not recruiting

Digital Health Feedback System for Longitudinal Measurement of Medication Adherence During Anti-Retroviral (ARV)Therapy

HIV

United States
NEAT ID Foundation
ViiV Healthcare

Completed

An Open-Label, Multi-Centre, Randomised, Switch Study to Evaluate the Virological Efficacy Over 96 Weeks Of 2-Drug Therapy With DTG/RPV FDC in Antiretroviral Treatment-Experienced HIV-1 Infected Subjects Virologically Suppressed With NNRTIs Resistance Mutation K103N (WISARD)

HIV-1-infection

Spain, Belgium, France, Germany, Italy, United Kingdom
American Gene Technologies International Inc.

Enrolling by invitation

An Antiretroviral Treatment Interruption (ATI) Study to Evaluate the Impact of Genetically Modified Autologous Cells (AGT103-T) to Suppress Human Immunodeficiency Virus Replication in the Absence of Antiretroviral Therapy

HIV

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Efficacy and Safety of Dolutegravir-Containing Versus Efavirenz-Containing Antiretroviral Therapy Regimens in HIV-1-Infected Pregnant Women and Their Infants (VESTED)

HIV Infections

United States, South Africa, Thailand, Botswana, Brazil, Tanzania, Zimbabwe, India, Uganda
Ottawa Hospital Research Institute
Gilead Sciences; CIHR Canadian HIV Trials Network

Completed

HIV Drug Switch Followed by HCV Therapy in HIV-HCV Co-Infection (CTN289)

Hepatitis C, Chronic | Human Immunodeficiency Virus

Canada
Boston University
Bill and Melinda Gates Foundation; University of Witwatersrand, South Africa

Withdrawn

Evaluation of Six-month HIV Treatment Dispensing in South Africa

HIV

South Africa
University of Cape Town
Wellcome Trust; Médecins Sans Frontières, Belgium

Completed

Tenofovir-lamivudine-dolutegravir Combination as Second-line ART: a Randomised Controlled Trial (ARTIST)

HIV Infections

South Africa
New York University
National Institute of Mental Health (NIMH); Beth Israel Medical Center; St. Luke...

Completed

Timely Initiation of HIV Antiretroviral Therapy Among Those Who Delay/Decline (Heart to Heart)

HIV | Antiretroviral Therapy

United States
CytoDyn, Inc.

Completed

Randomized, Double-Blind, Placebo-Controlled Trial, Followed by Single-Arm Treatment of PRO 140 (PRO140)

HIV

United States, Puerto Rico
New York University
Penn State University; Binghamton University

Completed

Using MOST to Optimize an HIV Care Continuum Intervention for Vulnerable Populations (HTH2-MOST)

HIV

United States
New York University

Completed

Supporting Health Behavior Among Persons Living With HIV Using Tech, MOST, and Behavioral Economics (SCAP2)

HIV Seropositivity | Adherence, Medication

United States
ViiV Healthcare
GlaxoSmithKline

Completed

ING200336, Pharmacokinetic and Safety Study in Pregnant Women With Human Immuno Virus Infection

HIV Infections | Arthralgia | Infection, Human Immunodeficiency Virus

Spain, Russian Federation
St. Jude Children's Research Hospital
Assisi Foundation; Cookies for Kids' Cancer

Completed

Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and Lymphoma

Recurrent B-Cell Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood B-Lymphoblastic Lymphoma

United States
RAND
Universidad Autonoma de Santo Domingo; Ministerio de Salud Publica, Dominican...

Completed

Improving Antiretroviral Therapy Adherence Through Urban Gardening and Nutritional Counseling in the Dominican Republic (ProMeSA)

HIV

Dominican Republic
MacroGenics
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

MGD014 in HIV-Infected Individuals on Suppressive Antiretroviral Therapy

HIV-1-infection

United States
Muhimbili University of Health and Allied Sciences
Fogarty International Center of the National Institute of Health; Kumamoto...

Suspended

The Effect of Aspirin on HIV Disease Progression Among HIV- Infected Individuals Initiating Anti- Retroviral Therapy

Cardiovascular Diseases | Hiv

Tanzania
HIV Prevention Trials Network
London School of Hygiene and Tropical Medicine; National Institute on Drug... and other collaborators

Completed

Population Effects of Antiretroviral Therapy to Reduce HIV Transmission (PopART) (PopART)

HIV

Zambia, South Africa
University of California, Berkeley
National Institute of Mental Health (NIMH); Health for a Prosperous Nation; R... and other collaborators

Completed

Optimizing the Efficiency and Implementation of Cash Transfers to Improve Adherence to Antiretroviral Therapy

HIV/AIDS | Adherence, Medication | Adherence, Patient

Tanzania
PACT Pharma, Inc.

Suspended

A Study of Gene Edited Autologous Neoantigen Targeted TCR T Cells With or Without Anti-PD-1 in Patients With Solid Tumors

Solid Tumor

United States
University of Cincinnati
Gilead Sciences; Abbott

Completed

Immune Reconstitution as a Determinant of Adverse Effects to New Antiretroviral Therapy in Persons With Advanced HIV Infection

HIV Infections

United States
University of Maryland, Baltimore
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Daily Trimethoprim-sulfamethoxazole or Weekly Chloroquine Among Adults on ART in Malawi (TSCQ)

HIV

Malawi
Albert Einstein College of Medicine
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Long Term Outcomes of Therapy in Women Initiated on Lifelong ART Because of Pregnancy in DR Congo (CQI-PMTCT)

HIV/AIDS | Antiretroviral Therapy | Pregnancy Outcomes | HIV-exposed Infants

Congo, The Democratic Republic of the
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy

HIV Infections

United States, Puerto Rico, Thailand, Botswana, Argentina, Brazil, Tanzania, South Africa
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Laboratory-Treated T Cells in Treating Patients With High-Risk Relapsed Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia Previously Treated With Donor Stem Cell Transplant

Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Recurrent Acute Myeloid Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Therapy-Related Acute Myeloid Leukemia | Donor | Hematopoietic Cell Transplant Recipient | HLA-A*0201 Positive Cells Present

United States
Valme University Hospital
Hospital General Universitario Elche; Hospital del SAS de Jerez; Clinica Universidad... and other collaborators

Completed

Efficacy and Safety of Therapy Against HCV Based on Direct-acting Antivirals in Real-life Conditions (FPSMON201401)

Chronic Hepatitis C Infection

Spain

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