Search clinical trials for: Dose response

Total 32945 results

Mirjana Cihoric

Completed

Preoperative High-dose Dexamethasone and Emergency Laparotomy

Sepsis | Inflammatory Response | Pathophysiology | Intestinal Obstruction and Ileus | Perforated Viscus

Denmark
Ain Shams University

Completed

Outcome of High Dose Vitamin D on Prognosis of Sepsis Requiring Mechanical Ventilation

Sepsis

Egypt
Rush University Medical Center

Completed

Levodopa Response and Gut Microbiome in Patients With Parkinson's Disease

Parkinson Disease

United States
Longeveron Inc.

Completed

Lomecel-B on Vaccine-Specific Antibody- Response in Subjects With Aging Frailty (HERA)

Aging Frailty

United States
Monument Therapeutics Limited
ICON plc

Completed

Safety & PK of Single Doses of MT1980

Neuroinflammatory Response

Netherlands
Azidus Brasil
Cellavita Pesquisa Científica Ltda

Completed

Dose-response Evaluation of the Cellavita HD Product in Patients With Huntington's Disease (ADORE-DH)

Huntington Disease

Brazil
Sun Yat-sen University

Completed

A Dose-response Study of Dietary Resveratrol on Lipid Metabolism Disorder

Dyslipidemias

China
Virginia Commonwealth University
University of Rwanda

Withdrawn

High-dose Intravenous Vitamin C as an Adjunctive Treatment for Sepsis in Rwanda

Sepsis

Rwanda
Guangzhou Women and Children's Medical Center

Completed

ED50 and ED95 of Intranasal Dexmedetomidine in Pediatric Patients Undergoing Transthoracic Echocardiography Study

Patients for Transthoracic Echocardiography | Unknown Diagnosis

China
Centre for Addiction and Mental Health

Completed

Dose-response of Cannabis and Driving

Cognitive Impairment | Driving Impaired | Abuse Cannabis

Canada
Johns Hopkins Bloomberg School of Public Health
Qidong Liver Cancer Institute

Completed

Broccoli Supplement Dose Response

Healthy Volunteers

China
Osivax
Centre for vaccinology (CEVAC), University of Ghent

Completed

Safety and Immune Response of One Dose of OVX836 at Two Dose Levels, in Comparison to Influvac TetraTM, After Intramuscular Administration in Healthy Subjects Aged 18-65 Years

Influenza

Belgium
Osivax
Aepodia

Completed

Safety and Immune Response of Increasing Doses of OVX836 After Intramuscular or Intranasal Administrations in Healthy Subjects

Influenza

Belgium
Fresenius Medical Care Deutschland GmbH

Terminated

Observation of the Immune Response After COVID-19 Additional Vaccine Doses in Chronic Patients in Hemodialysis Therapy (COVID-thIRd)

COVID-19 | Chronic Kidney Diseases | Hemodialysis

Spain, Portugal
Pennington Biomedical Research Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Dose-Response to Exercise in Women Aged 45-75 Years (DREW) (DREW)

Cardiovascular Diseases | Hypertension | Postmenopausal | Overweight or Obese

United States
AryoGen Pharmed Co.

Completed

Study on the Dose-response Relationship of Pharmacodynamic Parameters in Patients With Hemophilia With Inhibitors

Hemophilia A With Inhibitor | Hemophilia B With Inhibitor

Iran, Islamic Republic of
Albert Einstein College of Medicine

Completed

Sodium Bicarbonate Supplementation in Chronic Kidney Disease Evaluation of Dose Response, Safety and Beneficial Effects

Chronic Kidney Disease

United States
Heart Institute, Ministry of Health of Ukraine

Active, not recruiting

Anesthesia Standard Operating Procedure During On-pump Coronary Artery Bypass Grafting

Coronary Artery Disease | Postoperative Complications | Atrial Fibrillation | Low Cardiac Output Syndrome

Ukraine
Wake Forest University Health Sciences

Terminated

Fluid Resuscitation in Septic Shock Patients With BMI Elevation (FRISSBE)

Sepsis | Obesity | Septic Shock

United States
Mylan Inc.

Completed

Dose-Response Study of MR-107A-01 in The Treatment of Post-Surgical Dental Pain

Pain | Postoperative Pain | Pain, Acute

United States
GlaxoSmithKline

Completed

A Study to Assess the Safety, Reactogenicity and Immune Response of GlaxoSmithKline (GSK) Biologicals' Investigational Respiratory Syncytial Virus (RSV) Vaccine (GSK3844766A) in Older Adults

Respiratory Syncytial Virus Infections

United States, Belgium
Marion Trousselard

Terminated

Is Initial Response to Low Dose Risperidone Predictive for Outcome in Anxiety?

Anxiety State

France
University Health Network, Toronto

Completed

Third Dose of Moderna COVID-19 Vaccine in Transplant Recipients

Covid19 | Vaccine Response Impaired | Immune Suppression

Canada
Chang Gung Memorial Hospital
Medigen Vaccine Biologics Corp.

Active, not recruiting

The Immune Response of Heterologous Boost Third Dose of mRNA and Protein COVID-19 Vaccine

COVID-19 | Breakthrough Infection

Taiwan
Ain Shams University
Misr International University

Completed

Clinical Outcomes of High Dose Vitamin D Versus Standard Dose in COVID-19 Egyptian Patients

Covid19 | Vitamin D Deficiency | Corona Virus Infection | Cytokine Storm

Egypt
Procter and Gamble

Completed

Evaluation of the Fluoride Dose Response Using In Situ Caries Model

Caries

United States
Hanmi Pharmaceutical Company Limited

Completed

A Phase 2 Study to Assess Dose-response Relationship of HCP1803 in Patients With Essential Hypertension (HM_APOLLO)

Hypertension

Korea, Republic of
Vanderbilt University Medical Center

Completed

Senescent Immunity in Elders and Vaccine Responses (SILVER)

Flu Vaccine

United States
PepsiCo Global R&D

Completed

Dose Response Effect of Chia Seeds on Subjective Appetite and Glycemic Response

Nutrition, Healthy

Canada
Aventure AB

Completed

Second Meal Effects of a Wholegrain Cereal Product on Blood Glucose Response

Blood Glucose Response

Sweden
University of Bergen
Haukeland University Hospital

Active, not recruiting

Predictors for Response to Dose-dense Docetaxel and Epirubicin Breast Cancer (DDP)

Stage III Breast Cancer AJCC V7

Norway
Kindeva Drug Delivery

Completed

Single Blind Cross-over Dose Response Study in Subjects of Two Inhalers of Salmeterol and Fluticasone Propionate

Healthy

United Kingdom
Pfizer

Completed

A Double-blind Study to Assess 2 Doses of an Investigational Product for 16 Weeks in Participants With Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus

Non-alcoholic Steatohepatitis

United States, Canada
GlaxoSmithKline

Terminated

Safety, Tolerability, Efficacy and Dose-response of GSK2831781 in Ulcerative Colitis

Colitis, Ulcerative

United States, Netherlands, Ukraine, Estonia, Poland, France, Japan, Russian Federation, Slovakia, South Africa, United Kingdom, India, Bulgaria, Czechia, Serbia
Hvidovre University Hospital

Completed

Quadriceps Exercise Before Total Knee Arthroplasty (The QUADX-1 Trial) (QUADX-1)

Osteoarthritis, Knee

Denmark
Pentax Medical

Completed

Evaluation of Safety and Dose Response Using C2 CryoBalloon™ Swipe Ablation System for Barrett's Esophagus

Barrett Esophagus

Netherlands
Indiana University

Completed

Dose-response Effect of Dietary Nitrate on Muscle Function in Older Individuals

Sarcopenia | Aging

United States
Centre Hospitalier Universitaire de Nīmes

Completed

MIROCALS: Modifying Immune Response and OutComes in ALS (MIROCALS)

Amyotrophic Lateral Sclerosis

France, United Kingdom
Sanofi Pasteur, a Sanofi Company

Completed

Study to Assess the Immune Response and the Safety Profile of a High-Dose Quadrivalent Influenza Vaccine (QIV-HD) Compared to a Standard-Dose Quadrivalent Influenza Vaccine (QIV-SD) in Taiwanese Adults 65 Years of Age and Older

Influenza (Healthy Volunteers)

Taiwan
Fundacion GenesisCare
Hospital La Milagrosa; Hospital Vithas Valencia Consuelo

Suspended

Ultra Low Doses of Therapy With Radiation Applicated to COVID-19 (ULTRA-COVID)

Pneumonia, Viral | Cytokine Storm

Spain
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA)

Completed

Efficacy, Safety and Dose-Response Study Followed by Open-Label Study of Lofexidine Treatment of Opioid Withdrawal

Opioid Dependence | Acute Opioid Withdrawal Syndrome

United States
Wake Forest University Health Sciences
Lucerno Dynamics, LLC

Terminated

Infiltration Effect on SUV

Dose Response Relationship, Drug

United States
Centre Hospitalier Universitaire de Saint Etienne
Merck Sharp & Dohme LLC

Completed

Golimumab in Ulcerative Colitis (UC) Patients With Loss of Response (LOR) Followed by Dose Optimization (GOLILOR)

Ulcerative Colitis

France
Washington University School of Medicine

Completed

Assessing the Dose Response of a Lead Fiber Snack Prototype (FDR)

Microbiota | Gastrointestinal Microbiome

United States
Dr. Diane Lougheed
The Ontario Thoracic Society of the Ontario Lung Association; Queen's University...

Completed

Physiology of Cough in Asthma: Comparison of Sensory-Mechanical Responses to Mannitol and Methacholine Challenge Tests

Asthma | Cough Variant Asthma

Canada
Stony Brook University
University of North Carolina, Chapel Hill

Completed

Flu Vaccine Response in Patients on Biologic Therapies

Inflammatory Bowel Diseases | Immune Complex Diseases | Rheumatologic Disorder

United States
Organon and Co

Completed

A Phase 2, Trial to Investigate the Dose-Response Relationship of a Single Injection of Org 36286 (Corifollitropin Alfa) to Initiate Multiple Follicular Growth in a Controlled Ovarian (Study 38826)(P06055)(COMPLETED)

Fertilization
Epicentre
Kenya Medical Research Institute

Completed

Immunogenicity and Safety of Fractional Doses of Yellow Fever Vaccines (YEFE) (YEFE)

Yellow Fever

Uganda, Kenya
University of Washington
National Institute of Nursing Research (NINR)

Completed

Audio-visual Stimulation: Sleep Dose Response

Osteoarthritis | Pain, Chronic | Insomnia Chronic

United States
Pontificia Universidad Catolica de Chile

Completed

Immune Response to Third Dose of COVID-19 Vaccine in Solid Organ Transplant

COVID-19 | SARS-CoV-2 Infection | Solid Organ Transplant | Vaccine Response Impaired

Chile

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