Search clinical trials for: leucin

Total 317 results

National Cancer Institute (NCI)

Completed

A Phase II Study of PROSTVAC-V (Vaccinia)/TRICOM and PROSTVAC-F (Fowlpox)/TRICOM With GM-CSF in Patients With PSA Progression After Local Therapy for Prostate Cancer

Recurrent Prostate Carcinoma | Stage I Prostate Cancer | Stage III Prostate Cancer | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
University of Kentucky
Bayer

Withdrawn

Randomized Phase 2 Trial of Pre-chemotherapy Leukine vs. Leukine-Dexamethasone in Combination With Gemzar & 5-FU in Patients With Metastatic Renal Cell Carcinoma

Renal Cell Carcinoma
University of Florida

Terminated

Pharmacotoxicology of Trichloroethylene Metabolites

Healthy

United States
National Cancer Institute (NCI)

Completed

Vaccine Therapy, GM-CSF, and Interferon Alfa-2b in Treating Patients With Locally Advanced or Metastatic Cancer That Expresses Carcinoembryonic Antigen (CEA)

Adult Solid Neoplasm

United States
Federal Scientific Clinical Centre of Pediatric...

Unknown

L-leucine in Diamond Blackfan Anemia Patients

Diamond Blackfan Anemia

Russian Federation
Emory University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Granulocyte-Macrophage Stimulating Factor in the Treatment of Peripheral Arterial Disease (GPAD-2)

Peripheral Arterial Disease

United States
University of Oregon
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Muscle Regrowth During Physical Rehabilitation and Amino Acid Supplementation

Osteoarthritis

United States
University of Nottingham
Biotechnology and Biological Sciences Research Council

Completed

Effect of Obesity-derived Cytokines on Protein Turnover and Carbohydrate Metabolism in Human Skeletal Muscle

Obesity | Sarcopenia

United Kingdom
Maastricht University Medical Center

Completed

Habitual Protein Intake and Muscle Protein Synthesis (Pro-Hab)

Sarcopenia

Netherlands
University of Aarhus

Completed

Leucine and Beta-hydroxy-beta-methylbutyrate (HMB) as Anabolic Nutrients After 36 Hours of Fasting

Fasting | Metabolism | Nutrition Support

Denmark
Hospital Clinic of Barcelona

Completed

Study to Assess the Effect of Leucine Along With Resistance Exercise on Muscle Strength and Quality of Life in Elders

Ageing

Spain
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Children With Neuroblastoma

Neuroblastoma

United States, Canada, Australia, Switzerland, Puerto Rico, Netherlands, New Zealand
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell Tumors

Brain Tumor | Central Nervous System Tumor

United States, Canada, Puerto Rico, Australia, Netherlands, Switzerland
Immatics Biotechnologies GmbH
National Cancer Institute (NCI)

Terminated

Peptide-based Glioma Vaccine IMA950 in Patients With Glioblastoma

Glioblastoma

United States
M.D. Anderson Cancer Center

Terminated

Study of Azacytidine Followed by GM-CSF in Patients With Myelodysplastic Syndrome (MDS)

Leukemia

United States
National Cancer Institute (NCI)

Terminated

Vaccine Therapy and Sargramostim With or Without Docetaxel in Treating Patients With Metastatic Lung Cancer or Metastatic Colorectal Cancer

Extensive Stage Small Cell Lung Cancer | Recurrent Small Cell Lung Cancer | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

United States
Tanta University

Completed

Clinical Evaluation of Nanoionomer Filling in Primary Teeth (CENFPT)

Dental Caries

Egypt
Yonsei University

Completed

Effects of Long Term Calorie Restriction on Sphingomyelin and Amino Acids

Overweight | Obese

Korea, Republic of
University of Nottingham
Ajinomoto Co., Inc.

Unknown

Modulation of Muscle Protein Metabolism by Essential Amino Acids (Aj1B)

Old Age

United Kingdom
Genzyme, a Sanofi Company

Terminated

Comparison Study of Rituximab Plus Sargramostim to Rituximab Alone for Relapsed Follicular B-cell Lymphoma, a Form of Non-Hodgkin's Lymphoma (PREMIER)

Lymphoma, Follicular

United States, Puerto Rico
Emory University

Terminated

A Randomized Study of the Site for Growth Factor Injection for Patients Undergoing Autologous Stem Cell Transplantation

Cytokines

United States
Indiana University
Michael J. Fox Foundation for Parkinson's Research

Completed

PROGENI (Parkinson's Research: The Organized Genetics Initiative) Family Study of LRRK2 (Leucine-rich Repeat Kinase 2) (PROGENI)

Parkinson Disease

United States, Canada
Genzyme, a Sanofi Company

Terminated

Efficacy (Induction of Response/Remission) and Safety Study in Patients With Moderate to Severe Crohn's Disease

Crohn Disease

Israel, United States, Romania, Ukraine, South Africa, Canada, Australia, Bulgaria, Russian Federation, New Zealand, Brazil
Genzyme, a Sanofi Company

Terminated

Study of Sargramostim in Moderately to Severely Active Crohn's Disease

Crohn's Disease
Genzyme, a Sanofi Company

Terminated

Efficacy Study of Sargramostim in the Retreatment of Patients Who Have Crohn's Disease Who Have Previously Responded to Treatment With Sargramostim

Crohn Disease

United States
Genzyme, a Sanofi Company

Completed

Efficacy (Induction of Response/Remission) and Safety Study in Patients With Moderate to Severe Crohn's Disease

Crohn Disease

Switzerland, New Zealand, Canada, Australia, Brazil, Argentina, United Kingdom, Ukraine, Russian Federation
Genzyme, a Sanofi Company

Terminated

Safety and Efficacy Study in the Treatment of Pediatric Crohn's Disease

Crohn Disease

United States
Genzyme, a Sanofi Company

Terminated

Open-label Trial of Leukine in Active Crohn's Disease

Crohn Disease

Switzerland, United States, New Zealand, Canada, Australia, Brazil, United Kingdom, Ukraine, Russian Federation, Argentina
Vanderbilt University
Nutraceutical Discoveries, Inc.

Completed

Resveratrol-Leucine Metabolite Synergy in Pre-diabetes

Impaired Glucose Tolerance

United States
Imperial College London
Medical Research Council

Terminated

Novel Interventions in HIV-1 Infection (IMIRC1003)

HIV-1 Infection

United Kingdom
M.D. Anderson Cancer Center
Bayer

Completed

G-CSF Versus G-CSF Plus GM-CSF for Stem Cell Mobilization in NHL Patients

Lymphoma

United States
McMaster University

Completed

Effect of Supplementing a Mixed Macronutrient Beverage With Graded Doses of Leucine on Myofibrillar Protein Synthesis

Muscle Protein Synthesis

Canada
The Hospital for Sick Children

Completed

Upper Limit of Leucine Intake in Adults

Healthy

Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Previously Untreated Rhabdomyosarcoma

Stage III Adult Soft Tissue Sarcoma | Stage I Adult Soft Tissue Sarcoma | Stage II Adult Soft Tissue Sarcoma | Adult Rhabdomyosarcoma | Adult Malignant Mesenchymoma | Alveolar Childhood Rhabdomyosarcoma | Embryonal Childhood Rhabdomyosarcoma | Embryonal-botryoid Childhood Rhabdomyosarcoma | Previously... and other conditions

United States
Immatics Biotechnologies GmbH

Completed

IMA910 Plus GM-CSF With Low-dose Cyclophosphamide Pre-treatment in Advanced Colorectal Carcinoma Patients Following a Successful 12 Week First-line Treatment With Oxaliplatin-based Chemotherapy (IMA910-101) (IMA910-101)

Colorectal Carcinoma

United Kingdom, Romania, Belgium, Bulgaria, Germany, Hungary, Latvia, Poland, Serbia
National Cancer Institute (NCI)

Terminated

Vaccine Therapy With or Without Sargramostim in Treating Patients With Cancer

Unspecified Adult Solid Tumor, Protocol Specific

United States
University of Florida
National Institutes of Health (NIH)

Completed

Vitamin B6 Dependence of One-Carbon Metabolism

Vitamin B6 Deficiency

United States
Columbia University

Completed

The Effects of Leucine on Body Weight

Obesity | Overweight

United States
University of Sao Paulo

Completed

Leucine Supplementation and Skeletal Muscle Disuse

Disuse Atrophy

Brazil
University of Sao Paulo

Completed

Branched-chain Amino Acids, and Resistance Exercise on Skeletal Muscle Signaling Pathways

Healthy

Brazil
University of Sao Paulo

Suspended

Effects of Chronic Leucine Supplemetion on Glucose Homeostasis, Body Compositin, Muscle Mass and Strength of Healthy and Young Subjects

Effect of Chronic Leucine Supplementation on Glucose Homeostasis, Lipid Profile, Body Composition, and Muscle Mass and Strenght

Brazil
National Cancer Institute (NCI)

Completed

Vaccine Therapy and Sargramostim in Treating Patients With Stage IV Malignant Melanoma

Recurrent Melanoma | Stage IV Melanoma

United States
National Cancer Institute (NCI)

Completed

Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer

Ovarian Endometrioid Adenocarcinoma | Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Recurrent Breast Cancer | Stage IV Colon Cancer | Stage IV Rectal Cancer and other conditions

United States
National Cancer Institute (NCI)

Completed

Comparison of Chemotherapy Regimens in Treating Children With Relapsed or Progressive Rhabdomyosarcoma

Recurrent Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Alveolar Childhood Rhabdomyosarcoma | Embryonal Childhood Rhabdomyosarcoma | Embryonal-botryoid Childhood Rhabdomyosarcoma

United States
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy With Sargramostim and Interleukin-2 in Treating Children With Neuroblastoma

Recurrent Neuroblastoma | Disseminated Neuroblastoma | Regional Neuroblastoma

United States
National Cancer Institute (NCI)

Completed

Chemotherapy Plus Sargramostim in Treating Patients With Refractory Myeloid Cancer

Thrombocytopenia | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13... and other conditions

United States
National Cancer Institute (NCI)

Completed

Vaccine Therapy Plus Immune Adjuvant in Treating Patients With Chronic Myeloid Leukemia, Acute Myeloid Leukemia, or Myelodysplastic Syndrome

Adult Acute Myeloid Leukemia in Remission | Accelerated Phase Chronic Myelogenous Leukemia | Chronic Phase Chronic Myelogenous Leukemia | Previously Treated Myelodysplastic Syndromes | Relapsing Chronic Myelogenous Leukemia | Refractory Anemia With Excess Blasts | Refractory Anemia With Excess...

United States
M.D. Anderson Cancer Center
Bayer

Completed

Herceptin and GM-CSF for Metastatic Breast Cancer

Breast Cancer

United States
M.D. Anderson Cancer Center
Bayer

Completed

Immuno-Augmentation With GM-CSF of Pneumococcal Vaccine in Chronic Lymphocytic Leukemia Patients

Leukemia

United States
Texas A&M University

Completed

Hydrolyzed Casein and Whey Protein Supplementation and the Addition of Leucine to Induce Protein Anabolism in Malnourished COPD Patients

Chronic Obstructive Pulmonary Disease

United States

Search clinical trials for: leucin

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