Search clinical trials for: median effective dose

Total 34326 results

Purdue Pharma LP

Completed

Safety and Effectiveness of Buprenorphine Transdermal System in Elderly Subjects With Chronic Pain: Pilot Study.

Chronic Pain

United States
International Centre for Diarrhoeal Disease Research...
Karolinska Institutet

Completed

Zinc Supplementation in Shigella Patients

Testing Effect of Intervention
Kaiser Permanente

Completed

The Efficacy of Oral Steroids in the Treatment of Acute Sciatica

Sciatica

United States
University of Edinburgh
Pfizer

Completed

Effect of Regular Sildenafil on Blood Pressure and Arterial Function in Hypertension

Hypertension

United Kingdom
Corautus Genetics

Unknown

To Find the Best Dose of pVGI.1(VEGF2) to Benefit Angina Patients When Given With an Experimental Injection Catheter

Angina Pectoris

United States
Celgene Corporation
Prologue Research International

Terminated

Phase I/II Open-Label, Dose Escalation Study To Determine The Maximum Tolerated Dose And To Evaluate The Safety Profile of Lenalidomide (Revlimid® CC-5013) With Liposomal Doxorubicin In Subjects With Advanced Ovarian and Primary Peritoneal Carcinoma

Ovarian Cancer

United States
Université de Sherbrooke
Canadian International Development Agency

Completed

Study of the Management of Vaginal Discharge in West African Using Single Dose Treatments

Candidiasis | Vaginitis | Bacterial Vaginosis

Ghana, Guinea, Togo
Assistance Publique - Hôpitaux de Paris

Terminated

IMPROVE: Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy in ANCA Associated Systemic Vasculitis

ANCA Associated Systemic Vasculitis Including Wegener's | Granulomatosis and Microscopic Polyangiitis and | Renal Limited Vasculitis

France, United Kingdom
Medical University of Vienna

Completed

Effect of High-Dose Prednisolone (Solu Dacortin®) Treatment on Choroidal and Optic Nerve Head Blood Flow in Humans

Regional Blood Flow | Optic Disk

Austria
Halozyme Therapeutics

Completed

A Phase IIIB Dose Comparison Study of Subcutaneous Hydration With and Without Human Recombinant Hyaluronidase (HYLENEX) in Volunteer Subjects

Healthy

United States
University of Wuerzburg

Unknown

VELCADE as Maintenance Treatment in Patients With Multiple Myeloma Following Autologous Peripheral Blood Stem Cell Transplantation (PBSCT)

Multiple Myeloma

Austria, Germany, Italy
Samaritan Pharmaceuticals, Inc

Completed

A Dose Response and Safety Study of Procaine HCl in HIV-Infected Patients

HIV Infections

United States
Hamamatsu University
Maruyama Memorial General Hospital; Seirei Hamamatsu General Hospital; Iwata... and other collaborators

Completed

Study of the Relationship Between rHuEPO Dose, Serum ADPN, and Mortality in Patients Beginning Hemodialysis (HD)

Renal Dialysis
National Institute of Environmental Health Sciences...

Completed

Ozone Exposure and Dose Delivered to Human Lungs

Lung Disease

United States
Hacettepe University

Completed

Effectiveness of Physiotherapy on Postcesarean Pain and Functional Activities

Cesarean Section

Turkey
National Institute of Arthritis and Musculoskeletal...

Completed

Protective Brace to Prevent Hand and Arm Injuries

Carpal Tunnel Syndrome | Cumulative Trauma Disorders

United States
KK Women's and Children's Hospital
National Healthcare Group, Singapore

Completed

Trial Of Misoprostol And Dinoprostone Vaginal Pessaries for Cervical Priming (TROMAD Study)

Induction of Labour

Singapore
Weill Medical College of Cornell University
Schering-Plough

Completed

Comparison of PEG-Intron and Two Different Doses of Ribavirin for the Treatment of Chronic Hepatitis C In Treatment Naïve Subjects

Chronic Hepatitis C
Academy of Finland
Tampere University; Hospital District of Helsinki and Uusimaa; Coxa, Hospital... and other collaborators

Unknown

Study on Costs and Effects of Waiting Time in Total Hip and Knee Replacements

Osteoarthritis, Knee | Osteoarthritis, Hip

Finland
Cyberonics, Inc.

Terminated

Effectiveness Study Comparing Treatment With Drug(s) or Adjunctive VNS Therapy for Pharmacoresistant Partial Seizures

Epilepsies, Partial

United States
NeurogesX

Completed

Pilot Study of High-Dose Capsaicin Patches to Treat Postherpetic Neuralgia Pain

Pain | Peripheral Nervous System Diseases | Neuralgia | Herpes Zoster

United States
University of Otago
Australian and New Zealand College of Anaesthetists

Completed

Comparison of Two Different Doses of Paracetamol for Post-Operative Pain Relief

Adult Patients Scheduled for 3rd Molar Teeth Extractions

New Zealand
Agarwal, Pinky, M.D.
GlaxoSmithKline; Colorado Neurology

Unknown

Open Label High Dose Ropinirole (Requip) Study for Patients With Parkinson's Disease

Parkinson's Disease

United States
University of Texas Southwestern Medical Center

Completed

Impact of Low Dose Naloxone on Fentanyl Requirements in Pediatric ICU Patients

Opioid Tolerance

United States
Cell Genesys

Terminated

Intravenous CG7870 in Combination With Docetaxel in Patients With Metastatic Hormone-Refractory Prostate Cancer

Prostate Cancer

United States
The University of Hong Kong
The Health Care and promotion Fund, the Governement of the Hong Kong SAR.

Completed

Effectiveness of Screening and Counselling for Elderly With Psychological Problems

Mental Illness
Kwong Wah Hospital

Completed

Effects of 2 Different Doses of Pantoprazole on Gastric pH and Recurrent Bleeding in Patients Who Bled From Peptic Ulcers

Peptic Ulcer Hemorrhage

China
London School of Hygiene and Tropical Medicine
Medical Research Council; National Malaria Control Programme, The Gambia

Completed

Trial of the Effectiveness of AQ/AS, SP/AQ and SP/CQ for Uncomplicated Malaria in Gambian Children

Malaria

Gambia
Daiichi Sankyo, Inc.

Completed

A Comparison of the Effect of Olmesartan Medoxomil, Losartan Potassium, and Atenolol on the Ability of Overweight Patients With High Blood Pressure to Respond to Insulin

Hypertension | Metabolic Syndrome | Insulin Resistance

United States
National Taiwan University Hospital

Completed

Minimal Erythema Dose of UV-B in Normal Population of Taiwan

Human Volunteers

Taiwan
St George Hospital, Australia

Unknown

Boost Use in Breast Conservation Radiotherapy

Breast Neoplasms

Australia
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Randomized Trial Of Platelet Transfusion Policies After Blood Stem Cells Transplantation In Young Children: Reduction Of Number Of Single Platelet Concentrate Donors Per Child

Children Treated With High-Dose Chemotherapy (HDC) Followed by Haematopoietic Stem Cell Transplantation (HSCT)

France
Herlev Hospital

Unknown

Low-Dose Endotoxemia and the Acute Phase Response

Sepsis | Endotoxemia

Denmark
Chiron Corporation

Unknown

Kinetic of Immune Memory Response After Re-Vaccination With Meningococcal Vaccine

Meningococcal Disease; Meningococcal Meningitis

United Kingdom
University Hospital, Angers

Unknown

High Dose Hyperoncotic Serum Albumin for the Treatment of the Acute Phase of Severe Head Injury

Severe Head Injury

France
University of Padova
IL Sogno di Stefano; Regione Veneto

Unknown

Evaluation of the Effectiveness of Antibiotic Prophylaxis in Children With a Previous Urinary Tract Infection

Urinary Tract Infections

Italy
National Taiwan University Hospital

Unknown

Establishing Novel Detection Techniques for Various Genetic-Related Diseases by Applying DHPLC Platform.

Colon Cancer | Spinal Muscular Atrophy | Neonatal Hyperbilirubinemia

Taiwan
Poitiers University Hospital
Novartis; Ministry of Health, France

Terminated

Safety and Efficacy of Imatinib in Combination With High Dose Chemotherapy for Acute Phase Chronic Myelogenous Patients

Chronic Myeloid Leukemia

France
CONRAD

Completed

Contraceptive Effectiveness Trial of Cellulose Sulfate Gel

Contraception

United States
Gilead Sciences

Completed

Study Safety/Efficacy of AmBisome Loading Dose Regimen Versus Standard AmBisome Regimen for Initial Treatment

Invasive Aspergillosis | Other Fungal Infections
Centers for Disease Control and Prevention
Universidad del Valle, Guatemala

Completed

Effectiveness of Combined Albendazole and Ivermectin Treatment for Intestinal Worm Infections

Pediculosis | Strongyloidiasis | Ascariasis | Trichuriasis | Hookworm Infection

Guatemala
University of British Columbia

Completed

A Randomized Study to Compare Polysomnography With Overnight Home Oximetry and Auto - CPAP for Sleep Apnea

Obstructive Sleep Apnea

Canada
Hoffmann-La Roche
Trimeris

Completed

A Study to Compare Three Doses of T-20 When Given in Combination With Abacavir, Amprenavir, Ritonavir, and Efavirenz to HIV-Infected Adults

HIV Infections

United States
Zeneus Pharma

Unknown

Myocet, Docetaxel & Trastuzumab as 1st Line Treatment of Patients With HER-2/Neu Positive Metastatic Breast Cancer

Metastatic Breast Cancer

Italy
Celgene Corporation
Prologue Research International

Terminated

Phase I Open-Label, Dose Escalation Study To Determine The Maximum Tolerated Dose And To Evaluate The Safety Profile Of Lenalidomide (Revlimid®, CC-5013) With Pemetrexed In Subjects With Advanced Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

United States
London School of Hygiene and Tropical Medicine
British Council for Prevention of Blindness; Tanzanian Society for the Blind

Completed

Effectiveness of Alternative Approaches to Providing Spectacles in Tanzanian Secondary School Students

Under- and Uncorrected Significant Refractive Errors

Tanzania
Zeneus Pharma

Unknown

Open Label, Single Arm, Phase II Study Using R-COMP in Elderly Patients With Aggressive NHL.

Aggressive Non-Hodgkin's Lymphoma in the Elderly.

France, Germany, Spain, United Kingdom, Italy
Assistance Publique - Hôpitaux de Paris
Etablissement Français du Sang

Terminated

Study of the Effectiveness of Rituximab in Adults With Chronic and Severe Immune Thrombocytopenic Purpura and Candidate for a Splenectomy

Autoimmune Thrombocytopenic Purpura

France
iTech Medical, Inc.

Unknown

Study to Demonstrate That Muscle Pattern Recognition (MPR) is an Effective Evaluation Tool for Musculoskeletal Neck or Back Pain

Low Back Pain | Neck Pain

United States, Canada
North Bronx Healthcare Network

Completed

An Effective Alternative to the Standard Referral System for HIV Testing in the Emergency Department During Off Hour Tours: A Randomized Trial

HIV Infections | HIV Counseling and Testing

United States

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