Clinical Trials Sponsored by EMD Serono

Total 6664 results

EMS

Withdrawn

Efficacy and Safety of Lima Association in the Control of Type II Diabetes Mellitus.

Type2 Diabetes Mellitus
EMS

Completed

Efficacy and Safety of Saturno IIB Association on the Control of Ocular Inflammation Post-phacoemulsification

Ocular Inflammation | Cataract

Brazil
EMS

Withdrawn

Safety And Efficacy Study Of Topic Mucopolysaccharide Polysulfate Cream In The Superficial Varicose Veins Treatment

VARICOSE VEINS

Brazil
EMS

Withdrawn

Efficacy and Safety of Leningrado 5 Association in the Treatment of Hypertension

Arterial Hypertension
EMS

Withdrawn

Fixed-dose Combination of Valsartan + Rosuvastatin Versus Their Isolated Components for Hypertension and Dyslipidemia.

Hypertension | Dyslipidemia
EMS

Withdrawn

Non-Inferiority Comparison of Migrane® Versus Parcel ® For Treatment of Tensional Cephaleia

Tensional-type Headache
EMS

Completed

Efficacy Study of Methenamine + Methylthioninium Chloride vs Phenazopyridine for the Symptomatic Control of Dysuria

Dysuria

Brazil
EMS

Completed

Evaluation of Orlistat as Adjuvant Treatment of Obesity in Adults

Obesity

Brazil
EMS

Completed

Efficacy of Oral Famciclovir Versus Aciclovir Treatment in Patients With Herpes Zoster

Herpes Zoster

Brazil
EMS

Completed

Comparison of Desloratadine Associated With Prednisolone Oral Solution Versus Dexchlorpheniramine Associated With Betamethasone for Persistent Allergic Rhinitis Treatment

Allergic Rhinitis
EMS

Unknown

Comparison of Desloratadine Associated With Prednisolone (Tablet)Versus Dexchlorpheniramine Associated With Betamethasone (Tablet) for Adult Persistent Allergic Rhinitis Treatment

Allergic Rhinitis

Brazil
Aaron Brody, MD, MPH
Mar-Med

Unknown

Derma-Stent Novel Abscess Packing Device

Cutaneous Abscess

United States
Gazi University
Seroxo Ltd

Completed

Can Measurement of Neutrophil-derived ROS Production be a Novel Biomarker of Sepsis? (LIT-sepsis)

Infections | Sepsis | Septic Shock

Turkey
Hadassah Medical Organization
Merck Serono International SA

Terminated

Cetuximab Therapy for Third Line Rechallenge in Metastatic Colorectal Cancer

Cancer of Colon

Israel
AIO-Studien-gGmbH
Merck Serono GmbH, Germany

Terminated

Neoadjuvant Bintrafusp Alfa in Patients With Resectable Biliary Tract Cancer (NEOBIL)

Cholangiocarcinoma | Biliary Tract Cancer

Germany
Universitair Ziekenhuis Brussel
Merck Serono International SA

Completed

Endometrial Advancement After Rec or u-HCG Triggering

Infertility

Belgium
Nordica Fertility Clinic
Merck Serono International SA

Unknown

A Prospective Randomized Multicentre Study to Compare Crinone 8% Once Daily Versus Other Vaginal Progesterone.

IVF - Luteal Phase Support After Embryo Transfer

Denmark, Sweden
University of Malaya
Merck Serono International SA

Terminated

Induction and Concurrent Chemoradiotherapy With Cetuximab for Patients With Locally Advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

Malaysia
Universitair Ziekenhuis Brussel
Merck Serono International SA

Unknown

Luteal Supplementation With Rec-LH After GnRH-agonist Triggering in In Vitro (IVF)

Pregnancy | Pregnancy Loss

Belgium
Universitair Ziekenhuis Brussel
Merck Serono International SA

Unknown

Pregnancy Rates in IVF After Ovulation Triggering With Recombinant or Urinary Human Chorionic Gonadotrophin (HCG)

Pregnancy | Embryonic Development | VEGF

Belgium
French Cardiology Society
Merck Serono International SA

Completed

Assessment of Endothelial Vasomotricity After Treatment by Nicotinic Acid in Acute Coronary Syndrome (EVANACS)

Acute Coronary Syndrome (ACS)

France
Istituto Clinico Humanitas
Merck Serono International SA

Completed

Retrospective Trial on Low Prognosis Infertile Patients

Infertility, Female | Fertility Disorders
Merck KGaA, Darmstadt, Germany
Merck Serono Norway

Completed

A Phase IV, Prospective, Observational, Open Label, Single Centre Cohort Trial to be Conducted in Norway During One Year to Assess the Cumulative Pregnancy Rate in a New Series of In-vitro Fertilization (IVF) Treatment Cycles Following Three or More Previous IVF Treatment Cycles Without Live Birth

Infertility

Norway
Merck KGaA, Darmstadt, Germany
EMD Inc., Canada

Completed

Treatment Adherence When Using RebiSmart™ in Relapsing Multiple Sclerosis Subjects (MEASURE)

Multiple Sclerosis | MS

Canada
Sejong General Hospital
Sejong Research Institute

Completed

Decompression Sickness in Divers With or Without Patent Foramen Ovale (DIVER-PFO)

Foramen Ovale, Patent | Decompression Sickness

Korea, Republic of
Verona Pharma Inc

Completed

Pilot Study of Ensifentrine or Placebo Delivered Via pMDI in Hospitalized Patients With COVID-19

Coronavirus Infection | Covid-19 | SARS-CoV-2

United States
Serina Therapeutics

Active, not recruiting

A Study of Weekly Subcutaneous Injections of SER-214 in Subjects With Parkinson's Disease (PD), to Determine the Safety, Tolerability and Pharmacokinetic (PK) Profile of SER-214

Parkinson's Disease

United States
Second Genome

Terminated

Study of SGM-1019 in Patients With Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis

United States
Cure CMD

Recruiting

Congenital Muscle Disease Study of Patient and Family Reported Medical Information (CMDPROS)

Emery-Dreifuss Muscular Dystrophy | Congenital Myasthenic Syndrome | Limb-Girdle Muscular Dystrophy | Congenital Muscular Dystrophy With ITGA7 (Integrin Alpha-7) Deficiency | Alpha-Dystroglycanopathy (Congenital Muscular Dystrophy and Abnormal Glycosylation of Dystroglycan With Severe Epilepsy) and other conditions

United States
ART Fertility Clinics LLC
Merck Serono International SA

Completed

Step Down FSH Approach and Late Follicular Phase in Progesterone Level (FSH)

Progesterone Resistance

United Arab Emirates
Merck KGaA, Darmstadt, Germany
Merck Serono S.P.A., Italy

Completed

Dietary Supplement of Curcumin in Subjects With Active Relapsing Multiple Sclerosis Treated With Subcutaneous Interferon Beta 1a (CONTAIN)

Multiple Sclerosis

Italy
Merck KGaA, Darmstadt, Germany
Merck Serono S.P.A., Italy

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in Italy (ECOS ITA)

Growth Disorders

Italy
Merck KGaA, Darmstadt, Germany
Merck Serono S.A.S, France

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in France (ECOS FRA)

Growth Disorders

France
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

Drug-Drug Interaction of Cladribine and Pantoprazole in Multiple Sclerosis Subjects

Multiple Sclerosis
Merck KGaA, Darmstadt, Germany
Merck Serono GmbH, Germany

Completed

Determine the Improvement in Activity Status/Quality of Life (QoL) of Patients With Rheumatoid Arthritis (RA) During Treatment With Lodotra (Prednisone) (LODOTRA)

Arthritis, Rheumatoid

Germany
Merck KGaA, Darmstadt, Germany
Merck Serono Limited, UK

Completed

Assessment of Patient Use of a New Device: RebiSmart

Multiple Sclerosis
Merck KGaA, Darmstadt, Germany
Merck Serono S.A.S, France

Completed

Analysis of Two Therapeutic With Cetrotide® in Polycystic Ovarian (PCO) Women in Assisted Reproductive Technology (ART) (ATTAC-PCO)

Polycystic Ovarian Syndrome

France
Merck KGaA, Darmstadt, Germany
Merck Serono S.P.A., Italy

Completed

A Pilot Trial of Interferon Beta-1a in Alzheimer's Disease (REAL)

Alzheimer's Disease

Italy
Merck KGaA, Darmstadt, Germany
Merck Serono Limited, UK

Completed

Assessment of Subject Use of the Rebiject II Injection Device According to Nurse Examination of Subject Accuracy in 10 Steps as a Dummy Demonstration

Multiple Sclerosis
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

First Year Growth Response Associated Genetic Markers Validation Phase IV Open-label Study in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children: the PREDICT Pharmacogenetics Validation Study

Turner Syndrome | Idiopathic Growth Hormone Deficiency

Spain, France, Canada, United Kingdom, Czech Republic, Argentina, Germany, Italy, Sweden
Merck KGaA, Darmstadt, Germany
Merck Serono S.P.A., Italy

Terminated

A Trial to Evaluate the Correlation Between Spontaneous Catch-up Growth, Clinical Response to Saizen (Recombinant Human Growth Hormone, r-hGH) and Gene Expression Profiling in Children Small for Gestational Age (SGA) (SAIZEN in SGA)

Infant, Small for Gestational Age

Italy
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

An Observational Study for the Assessment of Adherence, Effectiveness and Convenience of Rebif® Treatment in Relapsing Multiple Sclerosis Patients Using RebiSmart™. (SMART)

Multiple Sclerosis, Relapsing-Remitting

Netherlands
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd.

Terminated

Efficacy and Safety of Crinone Versus Combination Medication (ACCESS)

Infertility

China
Merck KGaA, Darmstadt, Germany
Merck Serono Limited, UK

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in the UK (ECOS UK)

Growth Disorders

United Kingdom
Merck KGaA, Darmstadt, Germany
Merck Serono S.P.A., Italy

Terminated

Clinical Performance and Safety Investigation of ENDOmetrial Washing MEdical DEvice Forielle (ENDOMEDE)

Infertility

Italy
Merck KGaA, Darmstadt, Germany
Merck Serono S.A.S, France

Completed

Efficacy and Safety Evaluation of Recombinant Human Growth Hormone (r-hGH), Saizen®, on a Population of Children With Hypochondroplasia, Treated at Least 3 Years or Until Near Final Height, When Applicable, in Comparison With a Historic Cohort of Non-treated Children

Hypochondroplasia

France
Merck KGaA, Darmstadt, Germany
Merck Serono S.A.S, France

Completed

A Multicentre Study of the Efficacy and Safety of Supplementary Treatment With Cholecalciferol in Patients With Relapsing Multiple Sclerosis Treated With Subcutaneous Interferon Beta-1a 44 µg 3 Times Weekly (CHOLINE)

Multiple Sclerosis

France
University Hospital, Basel, Switzerland
Merck Serono International SA

Completed

Comparing Ovarian Stimulation for Assisted Reproduction With Two Different Forms of Pituitary Suppression (Pergoveris)

Complications Associated With Artificial Fertilization | Female Infertility Due to Nonimplantation of Ovum

Switzerland
Centre Hospitalier Universitaire, Amiens
Merck Serono International SA

Completed

May Metformin be Used in Renal Failure?

Renal Disorder Associated With Type II Diabetes Mellitus

France
Merck KGaA, Darmstadt, Germany
Merck Serono S.A.S, France

Completed

A Pharmaco-epidemiological Study of Short Patients Born Small for Gestational Age (SGA), Treated With Saizen® (Recombinant Somatropin) (SEPAGE)

Infant, Small for Gestational Age

France

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