Clinical Trials Sponsored by Hoffmann-La+Roche

Total 2458 results

Hoffmann-La Roche

Terminated

A Study of Capecitabine In Combination With Docetaxel vs Capecitabine Followed by Docetaxel As First-Line Treatment For Metastatic Breast Cancer

Breast Cancer

United States
Hoffmann-La Roche

Completed

A Study of RG7314 to Investigate Efficacy and Safety in Individuals With Autism Spectrum Disorders (ASD)

Autism Spectrum Disorder

United States
Hoffmann-La Roche

Completed

A Study to Determine Biopsy Rate in Participants With a First Relapse of Breast Cancer

Breast Cancer

Argentina
Hoffmann-La Roche

Completed

A Long-Term Extension Study of WA19926 on the Safety of Tocilizumab (RoActemra/Actemra) in Participants With Early Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

France
Hoffmann-La Roche

Completed

The Individualized Management With Pegylated-interferon Alfa-2a (Pegasys) and Ribavirin (Copegus) Offering Viral Eradication: A Study of Pegylated-interferon Alfa-2a Plus Ribavirin in Participants With Chronic Hepatitis C (CHC) Non-genotype 2/3 (IMPROVE) (IMPROVE)

Hepatitis C, Chronic

Canada, United States
Hoffmann-La Roche

Terminated

A Study of RO6885247 in Adult and Pediatric Patients With Spinal Muscular Atrophy (MOONFISH)

Muscular Atrophy, Spinal

France, Turkey, Canada, United States, Italy, Netherlands, Sweden, Switzerland, United Kingdom
Hoffmann-La Roche

Completed

A Dose-Finding Study of Subcutaneous Herceptin (Trastuzumab) in Healthy Male Volunteers and Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Females

Breast Cancer

New Zealand, Australia
Hoffmann-La Roche

Completed

A Study of Tocilizumab in Participants With Active Rheumatoid Arthritis (RA) and an Inadequate Response to Non-Biological Disease-modifying Anti-rheumatic Drugs (DMARDs)

Rheumatoid Arthritis

Montenegro
Hoffmann-La Roche

Completed

A Study of Subcutaneous C.E.R.A. for the Treatment of Anemia in Pre-Dialysis Patients.

Anemia

Russian Federation
Hoffmann-La Roche

Completed

A Long-Term Extension Study of WA22762 to Evaluate Safety and Efficacy of Subcutaneous Tocilizumab in Participants With Moderate to Severe Rheumatoid Arthritis (RA).

Rheumatoid Arthritis

France
Hoffmann-La Roche

Terminated

A Study of Herceptin (Trastuzumab) in Combination With Cisplatin/Capecitabine Chemotherapy in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Gastric or Gastro-Esophageal Junction Cancer (HELOISE)

Gastric Cancer

Germany, Spain, China, Korea, Republic of, United Kingdom, Philippines, Russian Federation, United States, New Zealand, Hungary, Italy, South Africa, Turkey, Bosnia and Herzegovina, Serbia, Czech Republic, Poland, Portugal, ... and more
Hoffmann-La Roche

Terminated

A Study of Erlotinib (Tarceva) in Participants With Resected Head and Neck Squamous Cell Cancer

Head and Neck Cancer

Spain
Hoffmann-La Roche

Completed

Effect of TRO19622 in the Treatment of Patients With Chemotherapy Induced Peripheral Neuropathy (CIPN)

Chemotherapy-Induced Peripheral Neuropathy

France
Hoffmann-La Roche

Terminated

A Study of Whole Brain Radiation Therapy and Capecitabine in Breast Cancer Participants With Newly Diagnosed Brain Metastasis (XERAD)

Breast Cancer

France
Hoffmann-La Roche

Completed

A Study To Assess the Quality and Strength of Bone in Women Participants With Osteoporosis Taking Oral Ibandronate Versus Placebo

Osteoporosis

United States
Hoffmann-La Roche

Completed

Study of Therapeutic Monitoring of Mycophenolate Mofetil (MMF/CellCept) After Kidney Transplantation

Kidney Transplantation

United States
Hoffmann-La Roche

Completed

A Long-Term Safety Extension Study of WA19926 in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

Hungary
Hoffmann-La Roche

Terminated

A Study of Subcutaneous Mircera, Versus no Erythropoiesis-Stimulating Agent (ESA) Therapy, in the Treatment of Anemia in Patients With Chronic Kidney Disease After Kidney Transplant

Anemia

France, United Kingdom, Germany, Spain, Belgium, Italy
Hoffmann-La Roche

Completed

A Non-Interventional Study of RoActemra/Actemra (Tocilizumab) Treatment in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Panama, Costa Rica, Dominican Republic, Guatemala
Hoffmann-La Roche

Completed

A Study of RO5095932 in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus Type 2

United States
Hoffmann-La Roche

Completed

A Study of The Effects of Multiple Doses of Ketoconazole on Single Dose Pharmacokinetics of RO4602522 in Healthy Male Volunteers

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Study of the Effect of Fluvoxamine on the Pharmacokinetics of RO4917523 in Healthy Volunteers

Healthy Volunteer

France
Hoffmann-La Roche

Completed

An Observational Study on the Safety Profile of MabThera/Rituxan (Rituximab) in Combination With Chemotherapy in Patients With B Cell-lineage Chronic Lymphocytic Leukaemia (MABERYC)

Lymphocytic Leukemia, Chronic

Spain
Hoffmann-La Roche

Completed

A Single Center Study to Evaluate the Penetration of RO7033877 Into the Lung in Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

An Observational Study of Tarceva (Erlotinib) in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer With Wild-Type Epidermal Growth Factor Receptor (EGFR) Gene (WILT)

Non-Squamous Non-Small Cell Lung Cancer

Spain
Hoffmann-La Roche

Completed

A Study of Combination Treatment With Pegasys (Peginterferon Alfa) and Copegus (Ribavirin)in Patients With Chronic Hepatitis C

Hepatitis C, Chronic

Israel
Hoffmann-La Roche

Completed

A Study of Hepatitis C Virus (HCV) Polymerase Inhibitor Pro-Drug in Combination With PEGASYS With or Without COPEGUS in Patients With Chronic Hepatitis C (CHC) Genotype 1 Infection.

Hepatitis C, Chronic

United States, Puerto Rico
Hoffmann-La Roche

Completed

Safety of Herceptin/Trastuzumab in Metastatic Breast Cancer

Breast Cancer, Metastatic Breast Cancer

Serbia
Hoffmann-La Roche

Completed

A Study on The Potential of Aleglitazar to Reduce Cardiovascular Risk in Patients With Stable Cardiovascular Disease and Glucose Abnormalities

Cardiovascular Disease, Diabetes Mellitus Type 2

Germany, Spain, Korea, Republic of, United States, Colombia, Mexico, Hungary, Canada, Austria, Estonia, Malaysia, Australia, Poland, Thailand, Czech Republic, Latvia, Italy, Romania, Russian Federation, Chile, Lithuania, Sweden, United... and more
Hoffmann-La Roche

Completed

A Long-Term Extension Study of RoActemra/Actemra (Tocilizumab) in Patients With Juvenile Idiopathic Arthritis Who Completed WA19977 Core Study

Juvenile Idiopathic Arthritis

Germany
Hoffmann-La Roche

Completed

A Study of P38 Inhibitor (4) in Patients With Active Rheumatoid Arthritis (RA) on Stable Methotrexate Therapy

Rheumatoid Arthritis

Germany, Poland, United States, Australia, Brazil, Canada, Estonia, Greece, Ireland, Mexico, New Zealand, South Africa, Spain, United Kingdom
Hoffmann-La Roche

Completed

A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO5545965 in Healthy Volunteers

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Study of Xeloda (Capecitabine) in Breast Cancer Patients With Central Nervous System (CNS) Progression

Breast Cancer

France
Hoffmann-La Roche

Completed

A Study of Xeloda (Capecitabine) in Patients With Advanced and/or Metastatic Colorectal Cancer

Colorectal Cancer

United States
Hoffmann-La Roche

Completed

An Observational Study of Tarceva (Erlotinib) in First Line in Patients With Advanced EGFR Mutation-Positive Non-Small Cell Lung Cancer (GERTAC)

Non-Squamous Non-Small Cell Lung Cancer

Germany
Hoffmann-La Roche

Terminated

A Non-Interventional Study of RoActemra/Actemra (Tocilizumab) in Monotherapy in Patients With Rheumatoid Arthritis (MONACO)

Rheumatoid Arthritis

Portugal
Hoffmann-La Roche

Completed

A Study of RO5285119 in Healthy Volunteers

Healthy Volunteer

France
Hoffmann-La Roche

Completed

A Study Comparing Mircera and Epoetin Beta for the Treatment of Anemia in Dialysis Patients With Chronic Kidney Disease.

Anemia

China, Hong Kong
Hoffmann-La Roche

Completed

A Study of the Effect of Taspoglutide on Gastric Emptying in Patients With Type 2 Diabetes

Diabetes Mellitus Type 2

Germany, United Kingdom
Hoffmann-La Roche

Completed

TESRA: (Treatment of Emphysema With a Gamma-Selective Retinoid Agonist)

Emphysema

United States, South Africa, Hungary, Poland, Bulgaria, Latvia, Israel, Italy, Czech Republic, United Kingdom, Ukraine, Iceland
Hoffmann-La Roche

Completed

A Study on the Effect of Renal Function on the Pharmacakokinetics of RO5024048 (Parent of Prodrug RO5024048) Following Multiple Oral Dose Administration of RO5024048

Healthy Volunteer

New Zealand, United States
Hoffmann-La Roche

Completed

A Study on the Effects of Valproate on the Pharmacokinetics of RO4917838 in Healthy Volunteers

Healthy Volunteer

France
Hoffmann-La Roche

Completed

A Study of Hepatitis C Virus (HCV) Polymerase Inhibitor Pro-Drug in Combination With PEGASYS Plus COPEGUS Compared With PEGASYS Plus COPEGUS in Patients With Chronic Hepatitis C Genotype 1 Infection.

Hepatitis C, Chronic

Australia, France, Italy, Spain, Germany, United States, Canada, Austria, Puerto Rico
Hoffmann-La Roche

Completed

A Study of Ibandronate (Bondronat) in Participants With Malignant Bone Disease

Pain; Bone Neoplasms; Neoplasm Metastasis

Bulgaria
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Monotherapy

Diabetes Mellitus Type 2

Korea, Republic of, China
Hoffmann-La Roche

Completed

A Pharmacokinetic Study of RO4917838 in Healthy Chinese Volunteers

Healthy Volunteer

China
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Oral Contraceptive Healthy Volunteers

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Retrospective Chart Review on the Use of Biologics in Monotherapy for the Treatment of Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

United Kingdom
Hoffmann-La Roche

Terminated

An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With Chronic Hepatitis B Who Have Failed Antiviral Treatment With Nucleoside (Nucleotide) Analogues

Hepatitis B, Chronic

Poland
Hoffmann-La Roche

Completed

A Study of Ibandronate (Bonviva) in Patients With Post-Menopausal Osteoporosis

Postmenopausal Osteoporosis

United States

3

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