Clinical Trials Sponsored by VertiFlex, Incorporated

Total 1171 results

Bausch & Lomb Incorporated

Completed

Safety and Efficacy Study of Topical Bromfenac Versus Placebo to Treat Ocular Inflammation After Cataract Surgery

Postoperative Complications | Cataract

United States
Gen-Probe, Incorporated

Withdrawn

Clinical Evaluation of the APTIMA® Assay for Chlamydia Trachomatis Using the PANTHER™ System

Chlamydia Trachomatis

United States
Bausch & Lomb Incorporated

Completed

Efficacy Study of Bromfenac Ophthalmic Solution in Patients Undergoing Cataract Surgery

Pain | Inflammation

United States
Bausch & Lomb Incorporated

Completed

Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery

Cataract

United States
Salient Pharmaceuticals Incorporated

Unknown

The Efficacy of CASAD in Patients With Diarrhea Related to Medullary Thyroid Cancer

Diarrhea | Medullary Thyroid Cancer

United States
Gen-Probe, Incorporated

Completed

Clinical Evaluation of the PROGENSA(Registered Trademark) Prostate Cancer Gene 3 (PCA3) Assay in Men With a Previous Negative Biopsy Result (PCA3)

Prostatic Neoplasms

United States
Bausch & Lomb Incorporated

Completed

Indomethacin Eyedrops Compared With Ketorolac Eyedrops for Ocular Inflammation Following Cataract Surgery

Inflammation | Cataract

Germany
Bausch & Lomb Incorporated

Completed

Corneal Endothelial Cell Density Changes In Healthy Subjects, When Administered ISV-403 for 5 Days

Healthy

United States
Pneuma Pharmaceuticals Incorporated

Terminated

Calfactant for Direct Acute Respiratory Distress Syndrome (CARDS)

Respiratory Distress Syndrome, Adult

Korea, Republic of, United States, Canada, New Zealand, Australia, Israel
Cook Group Incorporated

Completed

EVOLUTION® Duodenal Stent for Duodenal or Gastric Outlet Obstruction Caused by Malignant Neoplasms

Gastric Outlet Obstruction | Duodenal Obstruction

Australia, Netherlands, Canada, Czech Republic, Italy
Bausch & Lomb Incorporated

Completed

Loteprednol Ophthalmic Base Compared to Loteprednol Ophthalmic Suspension vs Placebo in an Allergen Challenge

Allergic Conjunctivitis

United States
Bausch & Lomb Incorporated

Completed

Co-Axial Micro-Incision Versus Co-Axial Small Incision Cataract Surgery Using the Stellaris Enhancement System

Cataract | Aphakia
Vertex Pharmaceuticals Incorporated

Approved for marketing

VX-770 Expanded Access Program

Cystic Fibrosis
Cook Group Incorporated

Completed

The ASPECT Study - Asian Paclitaxel-Eluting Stent Clinical Trial

Coronary Artery Disease

United States
Cook Group Incorporated

Completed

The ELUTES Clinical Trial (ELUTES I)

Coronary Artery Disease

United States
Cook Group Incorporated

Completed

In Stent ELUTES Study (ELUTES II)

Coronary Artery Disease

United States
Bausch & Lomb Incorporated

Completed

Loteprednol Etabonate Versus Vehicle for the Treatment of Inflammation and Pain Following Cataract Surgery

Pain | Inflammation

United States
Bausch & Lomb Incorporated

Completed

Assessment of the Concentrations of Besifloxacin, Moxifloxacin, or Gatifloxacin in the Aqueous Humor of Subjects

Cataract Extraction

United States
Bausch & Lomb Incorporated

Completed

Comparative Performance of a Bausch & Lomb Multipurpose Solution and Alcon OptiFree Replenish Multipurpose Solution

Adverse Effect of Contact Lens Solution

Malaysia
Bausch & Lomb Incorporated

Completed

Product Performance of a Toric Contact Lens

Astigmatism | Myopia

Malaysia
Bausch & Lomb Incorporated

Completed

Comparative Performance of PureVision Lens Designs

Myopia

Philippines, Malaysia
Bausch & Lomb Incorporated

Completed

Clinical Evaluation of a New Aspheric Intraocular Lens.

Cataract
Bausch & Lomb Incorporated

Completed

Comparative Performance of PureVision, Acuvue Oasys and O2Optix

Myopia

United States
Bausch & Lomb Incorporated

Completed

A Study to Investigate the Safety and Effectiveness of Aspheric Laser Refractive Surgery Treatments for Myopia

Astigmatism | Myopia
Bausch & Lomb Incorporated

Completed

A Study to Evaluate the Clinical Performance of a Novel Multipurpose Solution

Ocular Discomfort

United States
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-770 in Subjects With Moderate Hepatic Impairment and in Matched Healthy Subjects

In Development for Cystic Fibrosis

Czech Republic, Slovakia
Ideal Implant Incorporated

Completed

Upright Magnetic Resonance Imaging (MRI) Study - Breast Implant Shell Geometry and Edge Scalloping

Breast Augmentation
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-770 on Midazolam and Rosiglitazone and the Effect of Fluconazole on VX-770

Cystic Fibrosis

United States
Biosynexus Incorporated
GlaxoSmithKline

Completed

Safety and Pharmacokinetics Study in VLBW Neonates With BSYX-A110 (N002)

Neonatal Staphylococcal Sepsis

United States
Vertex Pharmaceuticals Incorporated

Completed

VX-950 and Peginterferon for Hepatitis C

Hepatitis C

Germany, Netherlands
Vertex Pharmaceuticals Incorporated

Completed

Phase 2 Study of VX-950, Pegasys and Copegus in Hepatitis C

Hepatitis C

United States, Puerto Rico
Vertex Pharmaceuticals Incorporated

Completed

Phase 2 Clinical Study in Psoriasis With Oral Investigational Drug VX-765

Psoriasis
Cook Group Incorporated

Completed

Randomized, Prospective Controlled Trial of Paraesophageal Hernia Repair With Small Intestinal Submucosa (SIS)

Hernia | Paraesophageal Hernia

United States
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of VX-407 in Healthy Participants

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

United States
Bausch & Lomb Incorporated

Not yet recruiting

A Study to Evaluate the enVista® Aspire (EA) Intraocular Lens in Subjects Undergoing Cataract Extraction

Cataract

United States
Bausch & Lomb Incorporated

Not yet recruiting

Study to Evaluate the Safety and Effectiveness of the enVista® Beyond (EY) EDF Intraocular Lens in Subjects Undergoing Cataract Extraction

Cataract

United States, Canada
Lexington Health Incorporated

Recruiting

Establishing a Correlation Between HRM and UGI MM Studies (MMvsMANO)

Esophageal Motility Disorders

United States
Bausch & Lomb Incorporated

Not yet recruiting

A Study to Evaluate the Safety and Efficacy of the Bausch + Lomb Myopia Control Lens for the Correction of Myopic Ametropia and Slowing the Progression of Myopia in Children

Myopia

China
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1 Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics, of VX-993

Pain

United States
Tvardi Therapeutics, Incorporated

Recruiting

A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

Hepatocellular Carcinoma

United States
Vertex Pharmaceuticals Incorporated

Recruiting

Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1- Mediated Proteinuric Kidney Disease Mediated Proteinuric Kidney Disease (AMPLITUDE)

Proteinuric Kidney Disease

United States, Spain, Ghana, France, United Kingdom, Belgium, Brazil, Colombia, Portugal, Canada, Puerto Rico, Netherlands
Vertex Pharmaceuticals Incorporated

Recruiting

A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

Diabetes Mellitus, Type 1 | Impaired Hypoglycemic Awareness | Severe Hypoglycemia

United States, Norway, Italy, Canada, France, United Kingdom, Switzerland, Netherlands, Germany
Cook Biotech Incorporated

Recruiting

Post-market Study of the Biodesign Hernia Graft

Ventral Hernia

United States, Canada
Vertex Pharmaceuticals Incorporated

Completed

A Phase 1 Dose Escalation Study of VX-973 in Healthy Adults

Pain

United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Renal Impairment

Pain

United States
Vertex Pharmaceuticals Incorporated

Active, not recruiting

Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis (CF) Participants 2 Years and Older

Cystic Fibrosis

United States, United Kingdom, Canada, Australia, Germany
Bausch & Lomb Incorporated

Completed

Clinical Study to Evaluate the Safety and Performance of the enVista® One-Piece Hydrophobic Acrylic Trifocal Intraocular Lens in Subjects Undergoing Cataract Extraction

Cataract

Canada
Bausch & Lomb Incorporated

Completed

Biotrue ONEday Contact Lenses With EPG03 Packaging Solution Compared to Biotrue ONEday Contact Lenses

Contact Lens Wearer

United States
Bausch & Lomb Incorporated

Completed

A Study to Evaluate the Safety and Effectiveness of a Contact Lens Cleaning and Disinfecting Solution

Refractive Ametropia

United States
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Relative Bioavailability and Food Effect of a New Tablet Formulation of VX-548

Pain

United States

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