Search clinical trials for: AL Amyloidosis

Total 475190 results

Boston Medical Center
Spectrum Pharmaceuticals, Inc

Terminated

Propylene Glycol-Free Melphalan Hydrochloride (Evomela) in AL Amyloidosis Patients

Amyloidosis; Systemic

United States
Medical College of Wisconsin

Terminated

Cardiac Uptake of 18F Florbetapir in Patients Undergoing Chemotherapy

Cardiac Amyloidosis

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Terminated

First-line Pomalidomide, Bortezomib, and Dexamethasone For AL Amyloidosis or LCDD

Primary Systemic Amyloidosis | Light Chain Deposition Disease

United States, Canada
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Suspended

3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
Columbia University

Completed

SGLT2 Inhibitors in Transthyretin Amyloid Cardiomyopathy

Transthyretin Amyloid Cardiomyopathy

United States
Sorrento Therapeutics, Inc.

Withdrawn

An Open-Label Study of the Safety of an Anti-CD38 Antibody Drug Conjugate (STI-6129) in Patients With AL Amyloidosis

Light Chain (AL) Amyloidosis
Pfizer

Completed

Burden of Disease Study In Patients With Transthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP) orTransthyretin Cardiomyopathy (TTR-CM) And Caregivers

Transthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP) | Transthyretin Cardiomyopathy (TTR-CM) | Familial Amyloid Cardiomyopathy | Senile Systemic Amyloidosis (SSA)
Oncology Institute of Southern Switzerland
University of Kiel; Ente Ospedaliero Cantonale, Bellinzona

Completed

Prevalence of Wild Type ATTR

Wild-type Transthyretin Amyloidosis

Switzerland
Pfizer

Completed

Vyndaqel Drug Use Investigation (Regulatory Post Marketing Commitment Plan)

Transthyretin Familial Amyloid Poluneuropathy
Alnylam Pharmaceuticals

Completed

Phase 2 Study to Evaluate ALN-TTRSC (Revusiran) in Patients With Transthyretin (TTR) Cardiac Amyloidosis

TTR-mediated Amyloidosis

United States, United Kingdom
European Myeloma Network
Janssen Pharmaceutica

Active, not recruiting

A Study of Daratumumab Monotherapy in Previously Untreated Patients With Stage 3B Light Chain (AL) Amyloidosis

Light Chain (AL) Amyloidosis, Stage 3B

Netherlands, Greece, France, Italy
Advice Pharma Group srl

Completed

MargheRITA (Remote Intelligence for Therapeutic Adherence) (MargheRITA)

Acute Myeloid Leukemia | Multiple Myeloma | Hodgkin Lymphoma | Amyloidosis | Chronic Lymphocytic Leukemia | Chronic Myeloid Leukemia | Treatment Adherence | Myelodysplasia | Lymphocytic Lymphoma | Treatment Adherence and Compliance | T Cell Non-Hodgkin Lymphoma | B-cell Non Hodgkin Lymphoma | Solitary Plasmacytoma and other conditions

Italy
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Transthyretin-Related Familial Amyloidotic Polyneuropathy (BioTRAP) (BioTRAP)

Transthyretin Amyloidosis | Transthyretin Amyloid Cardiopathy | Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy

India, Germany
First Affiliated Hospital Xi'an Jiaotong University

Enrolling by invitation

The Diagnostic Pattern and Prognosis of Multiple Myeloma Patients With Myocardial Amyloidosis Were Evaluated by NMR Based Metabolomics

Multiple Myeloma | Amyloidosis Cardiac

China
AZ Sint-Jan AV

Active, not recruiting

Cardiac Amyloidosis in Spinal Stenosis: the CASS-study (CASS)

Cardiac Amyloidosis

Belgium
Takeda
Takeda Development Center Americas, Inc.

Active, not recruiting

Ixazomib Rollover Study

Lymphoma | Multiple Myeloma | Amyloidosis

United States, China, Belgium, Canada, Poland, Spain, Korea, Republic of, Greece, Singapore, Japan, Sweden
Barbara Ann Karmanos Cancer Institute
Bristol-Myers Squibb; National Cancer Institute (NCI); Multiple Myeloma Research...

Active, not recruiting

Lenalidomide, Dexamethasone, and Elotuzumab With or Without Cyclophosphamide in Treating Patients With Relapsed Primary Amyloidosis

Recurrent Primary Amyloidosis

United States
Tufts Medical Center
Sanofi

Withdrawn

Isatuximab and Bendamustine in Systemic Light Chain Amyloidosis

Amyloidosis | Light Chain (AL) Amyloidosis
Ionis Pharmaceuticals, Inc.

Completed

Evaluate the Safety and Tolerability, as Well as the Pharmacokinetic and Pharmacodynamic Profiles of Single and Multiple Doses of Eplontersen Administered Subcutaneously to Healthy Volunteers and Patients With Hereditary Transthyretin-Mediated Amyloidosis (hATTR ).

Healthy Volunteers | hATTR Amyloidosis

Canada
University Hospital Inselspital, Berne

Active, not recruiting

ATTR Amyloidosis in Elderly Patients With Aortic Stenosis

Aortic Stenosis Symptomatic | Amyloidosis Cardiac

Switzerland
Massachusetts General Hospital

Completed

Combined Bone Marrow and Renal Transplantation for Hematologic Disorders With End Stage Renal Disease

Multiple Myeloma | Amyloidosis

United States
Assistance Publique - Hôpitaux de Paris

Completed

Early Diagnosis of TTR Amyloidosis by Use of Molecular Biology (ADDITION)

Diagnosis | Polyneuropathy | Idiopathic Progressive Neuropathy

France
Centre hospitalier de l'Université de Montréal...

Completed

Comparing the Hemodiafiltration On-line and Conventional Hemodialysis in Terms of Cost-benefit (PHARMACO-$)

Hemodialysis | Chronic Renal Failure

Canada
Centre Hospitalier Universitaire de Nīmes

Completed

Cerebellar Superficial Siderosis in Cerebral Amyloid Angiopathy (CSS)

Cerebral Amyloid Angiopathy | Siderosis

France
Weill Medical College of Cornell University
Karyopharm Therapeutics Inc

Withdrawn

Selinexor for Treatment of Light Chain Amyloidosis With Relapsed/Refractory Disease (STARR)

AL Amyloidosis | Amyloidosis | Amyloid

United States
Assistance Publique Hopitaux De Marseille

Completed

Expanding the Biomarkers in Familial Amyloid Neuropathy: MRI and Motor Unit Estimation by Electrophysiological Study

Amyloid Neuropathies | Transthyretin Amyloidosis

France
Icahn School of Medicine at Mount Sinai
Millennium Pharmaceuticals, Inc.

Completed

Ixazomib In Combination With Cyclophosphamide And Dexamethasone for Newly Diagnosed AL Amyloidosis

AL Amyloidosis

United States
European Myeloma Network

Completed

A Study on the Management and Outcome of Patients With Systemic AL Amyloidosis in Europe

AL Amyloidosis

Netherlands, Czechia, Austria, France, Germany, Greece, Italy, Portugal, Spain, United Kingdom
Neurozen Inc.
Chonnam National University Hospital; Chosun University Hospital

Completed

Evaluating the Efficacy of Artificial Intelligence-based Computer Aided Diagnosis Software That Assists in Determining Whether or Not to Conduct Amyloid PET for the Diagnosis of Alzheimer's Disease by Predicting Amyloid PET Positivity in Mild Cognitive Impairment Patients

Alzheimer Disease | Mild Cognitive Impairment

Korea, Republic of
Attralus, Inc.

Completed

A Study to Characterize the Biodistribution of 124I-Labeled AT-03 in Patients With Systemic Amyloidosis (AT03-001)

Amyloidosis; Systemic

United States
Attralus, Inc.

Active, not recruiting

A Study to Evaluate Organ Level Uptake Repeatability of 124I AT-01 in Subjects With Systemic Amyloidosis (AT01-001)

Amyloidosis

United States
Centre Hospitalier Universitaire de Nīmes

Completed

Study of Cerebral MRI Anomalies in Mutated Transthyretin Amyloidosis Patients (TTR-SNC)

Transthyretin Amyloidosis

France
Pusan National University Hospital

Completed

Comparison of OCTA Factors in Patients With or Without Amyloid Pathology: A Prospective Study

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Amyloid Angiopathy | Macular Ischemia

Korea, Republic of
Nantes University Hospital
Pfizer

Completed

Assessment of the Prevalence of TTR Amyloid Neuropathy in a Population of Patients With Neuropathy of Unknown Aetiology (PRE-TRANS)

Transthyretin Amyloidosis | Familial Amyloid Neuropathy

France
Stanford University

Withdrawn

Mixed Chimeric Transplantation for Primary Amyloidosis

Amyloidosis
CENTOGENE GmbH Rostock

Completed

Screening for the Transthyretin-Related Familial Amyloidotic Polyneuropathy (TTR FAP) (TRAP2-1)

Neuropathic Pain | Orthostatic Hypotension | Cardiac Failure | Gastrointestinal Disorders | Polyneuropathy, Amyloid

Spain, Austria, Hungary, North Macedonia, Poland, Serbia
Alnylam Pharmaceuticals

Completed

A Multicenter Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A Mutation

Polyneuropathy | Hereditary Transthyretin-mediated (ATTRv) Amyloidosis

United States
Selayang Hospital

Completed

A Randomised, Open-Label, Cross Over Group, Single-Centre Controlled Study To Evaluate The Clinical Performance Of Medium Cut-Off Membrane Dialyser Compared With High Flux Dialyser Among Patients With Chronic Haemodialysis (HD-1)

Quality of Life | Dialysis Amyloidosis | Hemodialysis-Associated Amyloidosis

Malaysia
Washington University School of Medicine

Completed

Sleep Quality and Amyloid-Beta Kinetics

Amyloid-beta

United States
Margarida Magalhaes-Silverman
National Cancer Institute (NCI)

Completed

Autologous Stem Cell Transplant Followed By Maintenance Therapy in Treating Elderly Patients With Multiple Myeloma

Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Primary Systemic Amyloidosis | Light Chain Deposition Disease | Extramedullary Plasmacytoma | Isolated Plasmacytoma of Bone

United States
Peking Union Medical College Hospital
Xian-Janssen Pharmaceutical Ltd.

Active, not recruiting

Daratumumab Combined With Bortezomib and Dexamethasone in Mayo 04 Stage III Light Chain Amyloidosis

Amyloidosis; Systemic

China
Brigham and Women's Hospital

Terminated

Imaging Cardiac Amyloidosis: A Pilot Study Using F-18 Florbetapir Positron Emission Tomography

Cardiac Amyloidosis

United States
Oncopeptides AB
PRA Health Sciences

Terminated

A Clinical Study of Melphalan Flufenamide (Melflufen) and Dexamethasone for Patients With Immunoglobulin Light Chain (AL) Amyloidosis

AL Amyloidosis

Spain, United Kingdom, Germany, Norway, Israel, France, United States, Czechia, Greece
University of Tennessee Graduate School of Medicine

Completed

124I-p5+14 Injection Safety in Subjects With Systemic Amyloidosis

Systemic Amyloidosis

United States
Eidos Therapeutics, a BridgeBio company

Completed

A Single Dose Study to Evaluate the Pharmacokinetics of Acoramidis Modified Release Formulations in Healthy Subjects

Amyloidosis

United Kingdom
Eidos Therapeutics, a BridgeBio company

Withdrawn

Efficacy and Safety of Acoramidis (AG10) in Subjects With Transthyretin Amyloid Polyneurophathy (ATTRibute-PN)

Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy
National Cancer Institute (NCI)

Completed

Melphalan and Dexamethasone With or Without Bortezomib in Treating Patients With Previously Untreated Systemic Light-Chain Amyloidosis

Primary Systemic Amyloidosis | Light Chain Deposition Disease

United States
Sherif S. Farag

Withdrawn

Analysis of Oral Mucositis in Patient's Undergoing Melphalan Conditioning and Autologous Stem Cell Transplant

Multiple Myeloma | Amyloidosis | Mucositis | Oral Mucositis

United States
The Cleveland Clinic

Completed

Carpal Tunnel Syndrome and Amyloid Cardiomyopathy

Carpal Tunnel Syndrome | Amyloidosis | Transthyretin Amyloidosis | Cardiomyopathy | Senile Systemic Amyloidosis

United States
The Cleveland Clinic

Completed

Screening for Systemic Amyloidosis Via the Ligamentum Flavum (ALF)

Amyloidosis | Spinal Stenosis | Amyloid | Transthyretin Amyloidosis | Primary Amyloidosis of Light Chain Type

United States

Search clinical trials for: AL Amyloidosis

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