Search clinical trials for: Human Animal Interaction

Total 28557 results

Boehringer Ingelheim

Completed

Drug-drug Interaction (DDI) With a P-gp Inhibitor, Organic Anion Transporting Polypeptide OATP-inhibitor, Food Effect

Healthy

Germany
Yale University
National Institute on Drug Abuse (NIDA); VA Office of Research and Development

Completed

Dronabinol Interactions With Cognitive Enhancing Drug in Humans

Marijuana Abuse | Cannabis

United States
ViiV Healthcare
GlaxoSmithKline

Completed

A Phase IV, Open Label, 4-period Cross-over Study to Investigate a Drug Interaction Between Lamivudine and Sorbitol Oral Solutions in Healthy Volunteers

Infection, Human Immunodeficiency Virus

United States
Istituto Clinico Humanitas
Agenzia Italiana del Farmaco

Unknown

Two Therapeutic Strategies for the Maintenance of Remission in Patients With Ulcerative Colitis (SCILLA)

Colitis, Ulcerative

Italy
GlaxoSmithKline

Completed

First Time in Human (FTIH) Study of GSK3008348 in Healthy Volunteers and Idiopathic Pulmonary Fibrosis Patients

Idiopathic Pulmonary Fibrosis

United Kingdom
Johns Hopkins University
University of Colorado, Denver; GlaxoSmithKline

Completed

Drug Interaction Study With Ribavirin and Abacavir in Male Subjects With Hepatitis C Who Have Failed Ribavirin Treatment

Hepatitis C | HIV

United States
University of Washington
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Early Connections, Early Detection and Intervention in Infants at Risk for Autism

Autism Spectrum Disorder

United States
Hypoglycaemia Research Group
Rigshospitalet, Denmark

Completed

The Impact of Renin-angiotensin System on Brain Activation During Hypoglycaemia in Healthy Men, a PET Study

Hypoglycemia | Cognitive Impairment

Denmark
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

A Study to Evaluate the Effect of Boceprevir and Telaprevir on Dolutegravir Pharmacokinetics in Healthy Adult Subjects (ING115697).

Infection, Human Immunodeficiency Virus

United States
University Hospital, Clermont-Ferrand
Neuromed IRCCS; Centre de Recherche en Nutrition Humaine d'Auvergne; Mediterranean...

Unknown

Diet Interactions With Human Gut Microbiota. The Potential Role of Mediterranean Diet Adherence. DIAGRAM, a Pilot Study (DIAGRAM)

Human Gut Microbiota

France
ViiV Healthcare
GlaxoSmithKline

Completed

GSK1349572 Drug Interaction Study With Fosamprenavir/Ritonavir

Infections, Human Immunodeficiency Virus and Herpesviridae

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Home Stimulation for Brain-Asphyxiated Infants

Hypoxia, Brain | Hypoxia-Ischemia, Brain

United States
Centre for Addiction and Mental Health
Brainsway

Completed

Does the Insula Control Smoking-Induced Dopamine Release? A TMS/[11C]-PHNO Study in Humans.

Healthy

Canada
Institut Pasteur
German Cancer Research Center; Versailles Saint-Quentin-en-Yvelines University and other collaborators

Completed

Dynamics of Human PApilloma Virus Interactions; Internet-based Students HeAlth Research Enterprise (DyPAVIR)

Infection by Human Papilloma Virus

France
Astellas Pharma Europe B.V.

Completed

First-in-human: Single Ascending Dose, Food Effect, Drug-drug Interaction, Multiple Ascending Dose, Proof of Pharmacology

Healthy Volunteers

United Kingdom, Germany
University of Copenhagen

Completed

Acute Effect of Animal and Vegetable Protein Rich Meals With Comparable Dietary Fibers Content on Appetite Sensation and Energy Intake (PAVA-II)

Obesity

Denmark
Bial - Portela C S.A.

Completed

Pharmacokinetic-pharmacodynamic Interaction Between BIA 3-202 and Levodopa/Benserazide

Parkinson's Disease (PD)

Portugal
Boehringer Ingelheim

Completed

Drug Drug Interaction Study Between BI 201335 and BI 207127 in Chronic Hepatitis C Infected Patients

Hepatitis C, Chronic

United States, Canada, Germany
Bial - Portela C S.A.

Completed

Pharmacokinetic-pharmacodynamic Interaction Between BIA 3-202 and Levodopa/Carbidopa

Parkinson's Disease

Portugal
National Taiwan University Hospital

Unknown

The Effect of Platelet Lysate on Corneal Epithelial Wound healing---the Collection of Human Serum From Volunteers

Comparison of Epitheliotrophic Ability Between Human Serum and Commercialized Human Platelet- Cell and Animal Model

Taiwan
Bial - Portela C S.A.

Completed

Pharmacokinetic-Pharmacodynamic Interaction Between Four Different Single Doses of BIA 3-202 and a Single Dose of Levodopa/Carbidopa (100/25 mg)

Parkinson's Disease

Portugal
Bial - Portela C S.A.

Completed

Pharmacokinetic-Pharmacodynamic Interaction Between Four Different Single Doses of BIA 3-202 and a Single Dose of Levodopa/Benserazide (100/25 mg)

Parkinson's Disease

Portugal
Marek Straczkowski

Completed

Beta-glucan and Insulin Sensitivity in Obese Humans

Obesity

Poland
University of Ulster
University College Dublin; University College Cork

Completed

Effect of Consuming Pork From Seaweed Extract Fed Animals on Antioxidant Status

Antioxidant Status, Inflammation

United Kingdom
Merck Sharp & Dohme LLC
Janssen Research & Development, LLC

Completed

Drug-Drug Interaction Between IDX719, Simeprevir, TMC647055 and Ritonavir When Administered in Combination in Healthy Participants (MK-1894-007)

Hepatitis C, Chronic
Merck Sharp & Dohme LLC

Completed

Study to Evaluate Drug-Drug Interaction Between IDX719 and Simeprevir in Healthy Participants (MK-1894-004)

Chronic Hepatitis C Infection
Merck Sharp & Dohme LLC

Completed

A Drug-Drug Interaction Study Evaluating the Combination of IDX320 and IDX184 in Healthy Participants (MK-6844-002)

Chronic Hepatitis C
Gitte Moos Knudsen
Center for Integrated Molecular Brain Imaging, Copenhagen, Denmak; Fertility... and other collaborators

Completed

Neuropsychobiological Correlates of Sex-steroid Hormone Manipulation in Healthy Women: a Risk Model for Depression (GnRHa)

Schizophrenia | Postpartum Depression | Menopause | Major Depressive Disorder | Neurodegeneration | Postpartum Psychosis

Denmark
ViiV Healthcare
GlaxoSmithKline

Completed

Effect of Rifampin (RIF) on the Pharmacokinetics (PK) of Oral Cabotegravir (CAB) in Healthy Subjects

Infection, Human Immunodeficiency Virus

United States
Wayne State University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Randomized Control Trial of an Animal-Assisted Intervention With Adjudicated Youth

Depression | Anxiety | Conduct Disorder

United States
Bial - Portela C S.A.

Completed

Pharmacokinetic-pharmacodynamic Interaction Between Three Different Single Doses of BIA 9-1067 and a Single-dose of Controlled-release 100/25 mg Levodopa/Benserazide

Parkinson's Disease (PD)

Portugal
European Organisation for Research and Treatment...

Unknown

Evaluation of FLT-PET and DWI-MRI in Patients With NSCLC Treated With a Platinum-based Doublet as Preoperative Chemo (EVIDENCE)

Non-small Cell Lung Carcinoma

Italy, United Kingdom
Parc de Salut Mar
Instituto de Salud Carlos III

Completed

Mephedrone and Alcohol Interactions in Humans

Alcohol-Related Disorders | Amphetamine-Related Disorders

Spain
University Hospital, Caen

Unknown

Interaction of Otolith Stimulation and Carotid Baroreflex in Humans (OTOBAR)

Healthy Volunteers

France
Medicago
Health Sciences Centre, Winnipeg, Manitoba; Syneos Health; Public Health Agency...

Completed

Safety, Tolerability and Immunogenicity of a Plant-made H7 Virus-like Particle (VLP) Influenza Vaccine in Adults.

RNA Virus Infections | Virus Diseases | Respiratory Tract Infections | Respiratory Tract Diseases

Canada
Boehringer Ingelheim

Completed

Drug Interaction Study With BI 201335 and Methadone or Buprenorphine/Naloxone

Hepatitis C

United States
Boehringer Ingelheim

Completed

Drug-drug Interaction of BI 201335 and Microgynon

Hepatitis C, Chronic

Germany
City of Hope Medical Center

Completed

Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2

Glioblastoma | Brain Tumor | Gliosarcoma | Anaplastic Astrocytoma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Giant Cell Glioblastoma | Anaplastic Meningioma | Mixed Glioma | Brain Stem Glioma | Ependymoblastoma | Grade III Meningioma | Meningeal Hemangiopericytoma | Pineal Gland Astrocytoma

United States
National Institute of Allergy and Infectious Diseases...

Completed

Effects of Ribavirin on Zidovudine or Stavudine

HIV Infections | Hepatitis C

United States
University of California, San Francisco

Completed

Pharmacokinetic Interactions Between an Herbal Medicine (African Potato) and Antiretroviral Agents (Lopinavir/Ritonavir) (AP6142)

Human Immunodeficiency Virus | Drug Interactions

United States
German Institute of Human Nutrition
University Hospital Tuebingen; Ernst von Bergmann Hospital; Ministry of Food... and other collaborators

Completed

Comparison of a Plant Protein Diet to a Animal Protein Diet Emphasized in Type 2 Diabetics (LeguAN)

Metabolic Diseases | Obesity | Diabetes Mellitus, Type 2 | Nutrition Disorders | Body Weight | Metabolic Syndrome x

Germany
Arne Astrup

Completed

Effect of Protein From Animal and Vegetable Sources on Appetite (PAVA)

Focus of Study: Appetite

Denmark
Environmental Protection Agency (EPA)

Completed

Interaction Effects of Temperature and Ozone (TROPICOZ)

Exposure to Environmental Pollution, Non-occupational

United States
Ottawa Hospital Research Institute
Merck Sharp & Dohme LLC

Withdrawn

A Drug Interaction Study of Boceprevir in Combination With Amlodipine or Diltiazem in Healthy Volunteers

Hypertension | Hepatitis C

Canada
Enanta Pharmaceuticals, Inc

Completed

Two-way Interaction Between Alisporivir and EDP239

Hepatitis C Virus

Germany
ViiV Healthcare
GlaxoSmithKline

Withdrawn

A Drug Interaction Study Evaluating Plasma GSK2248761 and GSK1349572 Pharmacokinetics in Healthy Adult Subjects.

Infection, Human Immunodeficiency Virus I

United States
Tufts University

Completed

Soybean Based Diets and CVD Risk Factors

Hypercholesterolemia

United States
Society of Indian Human & Animal Mycologist

Completed

SIHAM Candidemia Network:An Observational Study

Candidemia

India
Bayer

Completed

Effect of Ketoconazole on Regorafenib (BAY73-4506) Pharmacokinetics

Pharmacokinetics

United States
Gilead Sciences

Completed

Part A: Drug Interaction Study of Sofosbuvir and Antiretroviral Therapy (ART) Combinations in HIV and Hepatitis C Virus (HCV) Co-infected Patients. Part B: Efficacy and Safety of Sofosbuvir for 12 Weeks in HIV/HCV Co-infected Patients.

Hepatitis C | HIV

Puerto Rico

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