Search clinical trials for: Protective efficacy

Total 44340 results

Maltepe University

Completed

Assessment of the Efficacy of Injectable Hyaluronic Acid for Genitourinary Syndrome of Menopause

Genitourinary Syndrome of Menopause

Turkey
AstraZeneca
Syneos Health

Completed

Study to Assess the Safety and Preliminary Efficacy of AZD0156 at Increasing Doses Alone or in Combination With Other Anti-cancer Treatment in Patients With Advanced Cancer (AToM)

Advanced Solid Tumours

United States, Spain, Korea, Republic of, United Kingdom
Universiti Kebangsaan Malaysia Medical Centre
Institue of Microengineering and Nanoelectronics (IMEN), Universiti Kebangsaan... and other collaborators

Completed

Efficacy of Transdermal Microneedle Patch for Topical Anesthesia Enhancement in Paediatric Thalassemia Patients

Thalassemia in Children

Malaysia
Walter Reed National Military Medical Center

Terminated

Evaluation of Methylprednisolone or Ibuprofen on Efficacy of Nerve Blocks With Symptomatic Irreversible Pulpitis

Irreversible Pulpitis

United States
Galderma R&D

Completed

Safety and Efficacy of Treatment With Azzalure, Restylane/Emervel Filler and Restylane Skinbooster

Facial Aesthetic Treatment

Sweden, France
Galderma R&D

Completed

Study to Evaluate Efficacy, Safety and Injection Technique of Restylane Lip Volume and Restylane Lip Refresh

Injection Techniques

Sweden
Galderma R&D

Completed

Efficacy and Safety of Restylane Perlane Compared to Restylane for Correction of Moderate and Severe Nasolabial Folds

Nasolabial Folds in Chinese Population

China
Monash University Malaysia
Institut Jantung Negara

Completed

Safety and Efficacy of Tocotrienols in Post-CABG Atrial Fibrillation

Atrial Fibrillation

Malaysia
KLSMC Stem Cells, Inc.

Completed

Efficacy and Safety Study of Intra-Articular Injections of Autologous Peripheral Blood Stem Cells Following Subchondral Drilling Surgery for the Treatment of Articular Cartilage Injury in the Knee

Articular Cartilage Disorder of Knee | Articular Cartilage; Degeneration

United States, Malaysia
Chuncheon Sacred Heart Hospital

Terminated

Efficacy and Safety of G-CSF in Patients With Severe Alcoholic Hepatitis With Null or Partial Response to Steroid (GraCiAH)

Alcoholic Hepatitis

Korea, Republic of
Beijing Tiantan Hospital

Completed

Efficacy and Safety of Butylphthalide for Acute Ischemic Stroke Patients Receiving Intravenous Thrombolysis or Endovascular Treatment (BAST)

Acute Ischemic Stroke

China
Farjad Zafar

Completed

Comparison of Preoperative Analgesics on the Efficacy of Inferior Alveolar Nerve Block.

Symptomatic Irreversible Pulpitis

Pakistan
Baqiyatallah Medical Sciences University

Withdrawn

Efficacy and Safety of Mucoadhesive Sustained Release, Mucodentol, in Comparison With Hydroxychloroquine to Prevent COVID-19

COVID-19

Iran, Islamic Republic of
Galderma R&D

Completed

Efficacy and Safety of Therapy With Tri-Luma® Cream in Sequence With Glycolic Acid Peels for Melasma

Melasma

United States
Institut Cancerologie de l'Ouest

Completed

Efficacy and Tolerance Evaluation in FOLFIRINOX Dose Adjusted in Elderly Patients With a Metastatic Pancreatic Cancer (PAMELA70)

Toxicity | Pancreatic Metastatic Cancer

France
Eyenovia Inc.

Completed

Study of the Safety, Efficacy and PK of EYN-1601 in Dilation of the Pupil

Mydriasis

United States
State University of New York at Buffalo
National Center for Advancing Translational Sciences (NCATS)

Withdrawn

Dose-Ranging Study to Assess the Safety and Efficacy of Melatonin in Outpatients Infected With COVID-19

COVID-19

United States
Fundación Pública Andaluza para la Investigación...
Delos Clinical

Completed

Clinical Trial for Asses the Safety and Efficacy of Vitamin C and Vitamin E in Combination Versus Placebo for Treating Cognitive and Behavior Disorder in Children With Fragile X Syndrome (SXF2-8)

X Fragile Syndrome

Spain
King Abdulaziz University

Completed

The Efficacy of Pre-procedural Mouth Rinses on COVID-19 Saliva Viral Load

COVID-19 | Covid19 | SARS-CoV-2 | Coronavirus | Saliva | Viral Load | Polymerase Chain Reaction | Mouthwashes

Saudi Arabia
National Institute of Allergy and Infectious Diseases...

Completed

Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcipa...

Malaria

Mali
Sir Takhtasinhji General Hospital

Completed

First-day High Dose Vitamin C, E in Severe Birth Asphyxia (CEBA)

Birth Asphyxia

India
Hoffmann-La Roche

Completed

A Study Evaluating the Safety and Efficacy of Rituximab in Combination With Glucocorticoids in Participants With Wegener's Granulomatosis or Microscopic Polyangitis

Wegener's Granulomatosis or Microscopic Polyangiitis

India
Lithuanian University of Health Sciences

Completed

Efficacy of Proanthocyanidins in Non-Surgical Periodontal Therapy

Periodontitis, Adult

Lithuania
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Study of Evaluating the Efficacy and Safety of SHR4640 in Subjects With Gout

Gout

China
Thirty Respiratory Limited

Completed

A Study to Assess Efficacy and Safety of RESP301 Plus Standard of Care (SOC) Compared to SOC Alone in Hospitalized Participants With COVID-19

COVID-19

United Kingdom
Xiangya Hospital of Central South University

Completed

Efficacy and Economic Evaluation of Nonbiological Artificial Liver Therapy in Acute-on-chronic Hepatitis B Liver Failure.

Chronic-on-acute Liver Failure

China
Azienda Unità Sanitaria Locale Reggio Emilia

Completed

Evaluation of the Efficacy of High Doses of Methylprednisolone in SARS-CoV2 ( COVID-19) Pneumonia Patients

Covid19

Italy
Taipei Veterans General Hospital, Taiwan

Completed

The Efficacy of Ultrasound-guided Hydrodilatation With Hyaluronic Acid for Patients With Adhesive Capsulitis

Adhesive Capsulitis

Taiwan
University Hospital, Bonn
Charite University, Berlin, Germany; Heinrich-Heine University, Duesseldorf; University... and other collaborators

Terminated

"Multimodal Prevention of Psychosis - Investigating Efficacy of N-Acetylcysteine and Psychotherapy in CHR-Patients" (ESPRIT-B1)

Prodromal Schizophrenia

Germany
Massachusetts General Hospital

Suspended

A Pilot Study Investigating the Efficacy of Minocycline and N-Acetyl Cysteine for Bipolar Depression

Bipolar Disorder | Bipolar Depression

United States
Diffusion Pharmaceuticals Inc

Completed

Safety and Efficacy of Trans Sodium Crocetinate (TSC) in SARS-CoV-2 (COVID-19) Infected Subjects

SARS-CoV-2 (Covid19)

Romania
Chonbuk National University Hospital

Active, not recruiting

the Efficacy and Safety of Curcuma Longa Extract Mixture on Immune Enhancement

Immunity

Korea, Republic of
Universidad Europea de Madrid

Completed

Antioxidants Vitamins and Muscle Damage (Antioxidant)

Oxidative Stress

Spain
AMAG Pharmaceuticals, Inc.

Terminated

Study of the Efficacy and Safety of AMAG-423 (Digoxin Immune Fab) in Antepartum Subjects With Severe Preeclampsia

Severe Preeclampsia

United States, Poland, South Africa
Aristotle University Of Thessaloniki

Completed

Efficacy and Safety of Mydriatic Microdrops Compared With Standard Drops for Retinopathy of Prematurity (ROP) Screening: a Pilot Randomized Clinical Trial

Retinopathy of Prematurity

Greece
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Approved for marketing

Thymus Transplantation Safety-Efficacy

DiGeorge Syndrome | DiGeorge Anomaly | Complete DiGeorge Anomaly | Complete DiGeorge Syndrome

United States
Hospital Sao Domingos

Terminated

Tocilizumab Versus Methylprednisolone in the Cytokine Release Syndrome of Patients With COVID-19

Covid-19 | Cytokine Release Syndrome

Brazil
Genzyme, a Sanofi Company

Completed

Randomized Study of the Efficacy and Safety of a Single Dose of Synvisc-One® in Chinese Patients With Symptomatic Osteoarthritis of the Knee (C-SOUND)

Osteoarthritis

China
Hovid Berhad

Active, not recruiting

Efficacy and Safety of Tocotrienols in CADASIL

Cadasil

France
Eyenovia Inc.

Completed

Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation (MIST-2)

Mydriasis

United States
Eyenovia Inc.

Completed

Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation (MIST-1)

Mydriasis

United States
Reven Pharmaceuticals, Inc.

Active, not recruiting

Tolerability and Efficacy of RJX in Patients With COVID-19 (RJX)

COVID-19 | Acute Respiratory Distress Syndrome | SARS-CoV-2 | Hypoxemia

United States
Revision Skincare
Stephens & Associates, Inc.

Completed

A Clinical Study to Evaluate the Efficacy of an Anti-Aging Serum

Wrinkle | Photoaging | Fine Lines

United States
Radboud University Medical Center
Erasmus Medical Center; The PATH Malaria Vaccine Initiative (MVI); Havenzieke...

Completed

Safety and Protective Efficacy of Pb(PfCS@UIS4) (PbVac)

Plasmodium Falciparum | Malaria,Falciparum | Plasmodium Berghei | Controlled Human Malaria Infection (CHMI)

Netherlands
Bone Therapeutics S.A
Nordic Bioscience A/S

Completed

Phase III Study on the Safety and Efficacy of a Single Intra-articular Administration of JTA-004 in Symptomatic Knee Osteoarthritis (JTA-KOA2)

Symptomatic Osteoarthritis of the Knee

Denmark, Belgium, United Kingdom, Czechia, Hong Kong, Moldova, Republic of, Poland
University of North Carolina, Chapel Hill
Colgate Palmolive

Terminated

Antiviral Efficacy and Acceptability of Mouth Rinses for Inactivation of COVID-19 (COL)

Coronavirus Infection | COVID19 | SARS CoV-2 Infection

United States
The First Affiliated Hospital of Soochow University

Completed

A Safety and Efficacy Study of NAC in Patients With TA-TMA

Hematologic Diseases | Thrombotic Microangiopathies

China
University of Baghdad

Completed

The Efficacy of Oral Melatonin in Preventing Postoperative Delirium for Patients Undergoing Orthopedic Surgery Under General Anesthesia

Delirium | Delirium, Anesthesia Emergence

Iraq
MEDA Pharma GmbH & Co. KG

Completed

Assessment of Efficacy and Safety of Thioctic Acid in the Oral Treatment of Symptomatic Diabetic Neuropathy (SYDNEY 2)

Diabetic Polyneuropathy

Israel, Russian Federation
MEDA Pharma GmbH & Co. KG
Quintiles, Inc.; Ergomed; Clinquest, Inc.

Completed

Assessment of Efficacy and Safety of Thioctic Acid in the Oral Treatment of Diabetic Polyneuropathy (Stage 1 or 2) (NATHAN1)

Diabetic Polyneuropathy

United States, Spain, Croatia, Denmark, France, Italy, Netherlands, Sweden, United Kingdom

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