Search clinical trials for: United Kingdom

Total 191795 results

Leucid Bio

Recruiting

LEU01101: Safety and Preliminary Efficacy of LEU011 in Solid Tumours. (AERIAL)

Tumor, Solid

United Kingdom
Causeway Therapeutics

Recruiting

Efficacy and Safety of TenoMiR in Lateral Epicondylitis

Tennis Elbow

United Kingdom
Quince Therapeutics S.p.A.
Biotrial

Not yet recruiting

To Evaluate the Effects of EryDex in Patients With A-T (NEAT)

Ataxia Telangiectasia

Belgium, United States, Denmark, Germany, Italy, Norway, Poland, Spain, United Kingdom
Bordeaux Colorectal Institute Academy

Recruiting

Lumeneye Rectoscope for Assessment on Tumor Response After Total Neoadjuvant Treatment in Rectal Cancer (LUMEVAL)

Rectal Cancer

Netherlands, France, Italy, United Kingdom, Spain
Owlstone Ltd

Recruiting

Diagnostic Accuracy Study for OWL-EVO1 as a Lung Cancer EVOC® Probe (Evolution Phase 2)

Lung Cancer

United Kingdom, Czechia, Hungary
Celcuity Inc

Recruiting

Gedatolisib in Combination With Darolutamide in Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer | Prostatic Neoplasms, Castration-Resistant | Genital Diseases, Male | Prostatic Disease | mCRPC (Metastatic Castration-resistant Prostate Cancer) | Urogenital Diseases, Male

United States, France, Spain, United Kingdom
Population Health Research Institute
Canadian Institutes of Health Research (CIHR)

Recruiting

Evaluation of A Clinical Diagnostic Test for CRDS (DIAGNOSE CRDS)

Calcium Release Deficiency Syndrome (CRDS)

United States, Israel, Canada, Belgium, Denmark, France, United Kingdom
The Leeds Teaching Hospitals NHS Trust

Recruiting

The Use of Ventriject to Assess V02Max in Patients Admitted to Hospital in the Emergency Surgery Setting (LESS)

Emergencies | Surgery

United Kingdom
GlaxoSmithKline

Not yet recruiting

A First Time in Human Study to Evaluate the Safety and Tolerability of GSK3996401 Following Dosing With GSK4347859 in Healthy Participants

Systemic Lupus Erythematosus

United Kingdom
University of Aberdeen

Recruiting

Home Semen Analysis Tests as a Screening Tool for Fertility Patients

Male Infertility

United Kingdom
Northumbria Healthcare NHS Foundation Trust
GlaxoSmithKline; Newcastle University; Chiesi UK

Recruiting

Eosinopenia in Severe COPD Exacerbation (A-TREC)

Chronic Obstructive Pulmonary Disease

United Kingdom
AstraZeneca

Recruiting

A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors (CYCAD-1)

ER+ HER2- Advanced Breast Cancer | High-grade Serous Ovarian Cancer (HGSOC)

United Kingdom, Korea, Republic of, Australia, United States, Spain
University College, London
Place2Be; Anna Freud

Recruiting

Evaluating Knowledge Insight Tools (KIT) for Reducing Anxiety and Low Mood in UK Secondary School Students

Depression | Anxiety | Low Mood | Internalizing Problems

United Kingdom
Wave Life Sciences Ltd.

Recruiting

A Phase 1 Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1) (RestorAATion-1)

Alpha-1 Antitrypsin Deficiency

United Kingdom
Cardiff and Vale University Health Board
The European Vascular Research Collaborative (EVRC)

Not yet recruiting

Validating GLASS Score in Predicting Acute Limb Events in CLTI Patients (PROMOTEGLASS)

Chronic Limb-Threatening Ischemia

United Kingdom
University of Oxford

Recruiting

Hypertension Explored in Long-term Postpartum Follow-up in Later Life (HELPFUL)

Cardiovascular Diseases | Vascular Diseases | Cerebrovascular Disorders | Hypertension

United Kingdom
London North West Healthcare NHS Trust

Recruiting

SECURE Trial: Stress Echocardiography With Carotid Ultrasound vs Routine CT Coronary Angiography in Chronic Coronary Syndrome for Endpoints (SECURE)

Coronary Artery Disease | Coronary Disease | Chronic Coronary Syndrome

United Kingdom
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1) (Galileo)

Myotonic Dystrophy Type 1 (DM1)

United Kingdom, Canada
Alexion Pharmaceuticals, Inc.

Recruiting

Study of ALXN2220 Versus Placebo in Adults With ATTR-CM (DepleTTR-CM)

Transthyretin Amyloid Cardiomyopathy

United States, Spain, United Kingdom, Norway, Israel, Korea, Republic of, Belgium, France, Germany, Italy, Japan, China, Australia, Argentina, Austria, Taiwan, Switzerland, Canada, Sweden, Poland, Denmark, Turkey, Brazil, Netherlands, G... and more
University of Reading
Naturex

Recruiting

Enhancement of Calmness and Mood Following Acute Lemon Balm Supplementation During Cognitive Demand in Adults (LemCog)

Stress | Mood Disturbance

United Kingdom
University Health Network, Toronto
University College London Hospitals; Brigham and Women's Hospital; University... and other collaborators

Recruiting

The STOP-MED CTRCD Trial (STOP-MED)

Heart Failure | Cancer | Cardiotoxicity | Cardiac Toxicity | Antineoplastics Toxicity

Canada, United States, United Kingdom, Australia
Imperial College London
Imperial College Healthcare NHS Trust

Recruiting

Diagnostics in the Leg Ulcer Pathway

Venous Leg Ulcer

United Kingdom
Bolt Medical

Recruiting

Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACTURE) (FRACTURE)

Coronary Artery Disease | Coronary Artery Calcification

Netherlands, United Kingdom
Agomab Spain S.L.

Recruiting

Phase I Study to Assess Safety, Tolerability, PK and PD of AGMB-447 in Healthy Participants and Participants With IPF

IPF

United Kingdom
Ourotech, Inc.
Barts & The London NHS Trust; Imperial College Healthcare NHS Trust; Hampshire... and other collaborators

Recruiting

Prospective Evaluation of AI R&D Tool for Patient Stratification - MoA Evaluation in Triple Negative Breast Cancer (PEAR-MET) (PEAR-MET)

Breast Cancer | Triple Negative Breast Cancer

United Kingdom
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)

Dermatitis Atopic

Japan, China, Spain, United States, Argentina, United Kingdom, Denmark, Sweden, Turkey
Imperial College London

Recruiting

The Use and Reproducibility of Duplex Ultrasound to Provide Indices of Left Common Iliac Vein Diameter

May-Thurner Syndrome

United Kingdom
University Hospitals, Leicester
Jafron Biomedical Company Limited

Not yet recruiting

Pilot Study on HA380 Column Use in Critically Ill Patients Receiving Extracorporeal Support. (HACEC)

Inflammation | Acute Kidney Injury | ARDS | Extracorporeal Circulation; Complications

United Kingdom
Liverpool School of Tropical Medicine
Fred Hutchinson Cancer Center; University of Oxford; University of Liverpool; Malawi-Liverpool-Wellcome... and other collaborators

Not yet recruiting

A Controlled Human Infection Model (CHIM) With Intradermal BCG in Malawi (MLWBCGCHIM)

Tuberculosis

Malawi
Robert Jones and Agnes Hunt Orthopaedic and District...

Recruiting

A Novel Study Evaluating Patients Awaiting Total Hip Arthroplasty (PRIORITEES) (PRIORITEES)

Hip Replacement

United Kingdom
University of Roehampton

Recruiting

Efficacy of Cholesterol-lowering L. Plantarum on Cardiometabolic Health Biomarkers in Coeliac Disease Patients (ProCoChoL)

Celiac Disease

Italy, United Kingdom
The Leeds Teaching Hospitals NHS Trust

Recruiting

Neurostimulation in Intermittent Claudication

Claudication

United Kingdom
Daiichi Sankyo
AstraZeneca

Recruiting

A Study to Provide Continued Access to and Assess Long-Term Safety of the Study Drug(s)

Metastatic Cancer | Advanced Cancer

Spain, Korea, Republic of, Belgium, France, Italy, United States, Australia, Japan, Taiwan, United Kingdom
University Hospitals of North Midlands NHS Trust

Not yet recruiting

Trans-radial Superior Rectal Artery Embolisation for Haemorrhoids

Hemorrhoids

United Kingdom
ACADIA Pharmaceuticals Inc.

Recruiting

Study of Carbetocin Nasal Spray for the Treatment of Hyperphagia in Prader-Willi Syndrome

Hyperphagia in Prader-Willi Syndrome

United States, Canada, United Kingdom
Autolus Limited

Recruiting

A Study of CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL)

Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia | Relapsed or Refractory B Cell Non-Hodgkin Lymphoma

United Kingdom
Alexion Pharmaceuticals, Inc.

Recruiting

A Study to Evaluate Potential Drug Interactions Between ALXN2080 and Itraconazole, Fluconazole & Carbamazepine in Healthy Adults

Healthy

United Kingdom
University of Portsmouth

Not yet recruiting

The Effect of Chlorhexidine on the Oral Microbiome and Saliva in Dental Erosion

Dental Erosion

United Kingdom
King's College Hospital NHS Trust

Recruiting

Low-dose Tolvaptan for Inpatient Hyponatraemia.

Hyponatremia | SIADH

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Recruiting

Evaluation of the Implementation of Personalised Follow-up in Head and Neck Cancer (EMPOWER)

Head and Neck Cancer

United Kingdom
University Hospitals of North Midlands NHS Trust

Recruiting

What is the Experience of the Professional Nurse Advocates (PNAs) Application of the A-EQUIP Model Into Practice

Professional Role | Staff Attitude

United Kingdom
Enanta Pharmaceuticals, Inc
hVIVO Services Limited

Recruiting

A Controlled Phase 2a Study to Evaluate the Efficacy of EDP-323 Against Respiratory Syncytial Virus Infection in a Virus Challenge Model

RSV Infection

United Kingdom
GlaxoSmithKline
Medicines for Malaria Venture

Recruiting

A Study to Investigate the Safety of GSK4024484 in Healthy Adult Participants

Malaria, Falciparum

United Kingdom
Keele University
Norfolk and Norwich University Hospitals NHS Foundation Trust; University of... and other collaborators

Recruiting

Developing Allogeneic Musculoskeletal Therapies

Osteoarthritis

United Kingdom
Imperial College London
Imperial College Healthcare NHS Trust

Recruiting

Volatile Organic Compounds as Breath Biomarkers in Squamous Oesophageal Neoplasms (ViSON)

Oesophageal Squamous Cell Carcinoma | Oesophageal Cancer

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Not yet recruiting

The Psychological Impact of GTN on Women Who Have Completed Chemotherapy Treatment (PI-GTN)

Gestational Trophoblastic Neoplasia

United Kingdom
AstraZeneca

Recruiting

A Study to Investigate the Effect of Baxdrostat on Ambulatory Blood Pressure in Participants With Resistant Hypertension (Bax24)

Resistant Hypertension

Spain, Argentina, United States, Belgium, Czechia, Vietnam, Thailand, Australia, Turkey, Philippines, Greece, Taiwan, United Kingdom, Poland, South Africa, Canada, Germany, Hungary, Malaysia, Bulgaria, Saudi Arabia, Slovakia
ViiV Healthcare

Recruiting

A Study to Investigate the Relative Bioavailability and Food Effect of an Oral Capsid Inhibitor Tablet Formulation Compared With Other Oral Tablet Formulations in Male and Female Healthy Participants

HIV Infections

United Kingdom
Chiesi Farmaceutici S.p.A.

Recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled CHF6333 After Single Doses in Healthy Volunteers and After Single and Repeated Doses in Subjects With Bronchiectasis

Bronchiectasis

United Kingdom
Imperial College London
National Institute for Health Research, United Kingdom

Recruiting

GRACE: Evaluating Compression Stockings in Patients That Require Extended Duration Pharmacological Thromboprophylaxis (GRACE)

Surgery | Venous Thromboembolism

United Kingdom

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