Search clinical trials for: complement dose

Total 23305 results

Closed Loop Medicine
Pharmanovia

Recruiting

Personalised Dose Optimisation of Zestril Supported by the Digital Blood Pressure Diary in a Primary Care Environment in England: Pragmatic Observational Pilot Study for Remote Hypertension Treatment (OptiZest)

Uncomplicated Hypertension

United Kingdom
Shanghai Synergy Pharmaceutical Sciences Co., Ltd.

Not yet recruiting

A Single Dose Escalation Study of HHT201 in Healthy Subjects

Alzheimer Disease

China
Hao Tang

Recruiting

Deep Learning Reconstruction Algorithms in Dual Low-dose CTA

Deep Learning

China
Apollo Therapeutics Ltd

Not yet recruiting

A Study to Investigate APL-4098 Alone and/or in Combination With Azacitidine in R/R AML and High-Risk MDS

Myelodysplastic Syndrome With Excess Blasts | Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory | Myelodysplastic Syndrome Acute Myeloid Leukemia
Ting Chang, MD

Not yet recruiting

Safety and Efficacy of CD19-BCMA Targeted CAR-T Therapy for Refractory Generalized Myasthenia Gravis

Myasthenia Gravis

China
Eilean Therapeutics

Not yet recruiting

Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated Relapsed or Refractory Acute Myeloid Leukemia

AML With Gene Mutations

Australia
Ain Shams University

Recruiting

Assessment Of Dose-Dependent Immunomodulatory Effect Of Alveofact With or Without Steroisd In Neonatal RDS

Inflammatory Response | Preterm Birth | Premature Lungs | Neonatal Respiratory Distress Syndrome | Neutrophil Extracellular Trap Formation

Egypt
Jessica Merlin
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Pain Self-Management and Patient-Oriented Dosing for Pain and in Retention Opioid Treatment (TREETOP)

Chronic Pain | Opioid Use Disorder

United States
Children's Oncology Group

Not yet recruiting

A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

Central Nervous System Germinoma | Diabetes Insipidus | Pineal Region Germinoma | Suprasellar Germinoma
Brigham and Women's Hospital
Open Medicine Foundation

Not yet recruiting

LIFT: Life Improvement Trial (LIFT)

ME/CFS
Jafar Bakhshaie
National Center for Complementary and Integrative Health (NCCIH)

Not yet recruiting

Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use

Substance Use | Orthopedic Disorder | Upper Extremity Problem | Nontraumatic Injury

United States
CT Glaucoma Associates

Recruiting

How Much Does Reduced Dosing of Latanoprost and Dorzolamide-timolol Affect Pressure?

Glaucoma, Open-Angle | Glaucoma; Drugs

United States
University of California, Berkeley

Not yet recruiting

Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults

Aging
Universidad Peruana Cayetano Heredia
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

One and Two Doses of Oxfendazole Versus a Schedule of Two Doses of Triclabendazole in Chronic Fascioliasis

Fascioliasis
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

Pharmacology of Mupirocin in Nasal Application in Healthy Volunteers: Monocentric Study (MUPIPHARM)

Healthy | Staphylococcus Aureus Infection

France
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Phase Ib/II Trail of Neoadjuvant of Tislelizumab Combined With Palbociclib in Patients With Platinum-refractory Bladder Urothelial Carcinoma

Bladder Cancer

China
Taipei Veterans General Hospital, Taiwan

Recruiting

Evaluate the Efficacy of Adding Intraluminal Brachytherapy After CCRT for Local-regional Thoracic Esophageal Cancer.

Digestive System Diseases | Gastrointestinal Diseases | Neoplasms | Neoplasms by Site | Gastrointestinal Neoplasms | Digestive System Neoplasms | Head and Neck Neoplasms | Esophageal Neoplasms | Esophageal Diseases

Taiwan
Astellas Pharma Inc

Recruiting

A Study to Find a Suitable Dose of ASP4396 in Adults With Solid Tumors

Solid Tumor

United States
Andrea DeCensi
Herbert Irving Comprehensive Cancer Center; Breast Cancer Research Foundation; Istituto Europeo di Oncologia and other collaborators

Not yet recruiting

Low Dose Tamoxifen vs Low Dose Exemestane in Post-menopausal Women at High Risk for Breast Cancer. (BabyTears)

Breast Cancer

Italy
ITB-Med LLC

Recruiting

A Dose Escalation Study of TCD601 Compared to ATG in de Novo Renal Transplantation

Kidney Transplantation

Spain, Sweden, Austria
Kylonova (Xiamen) Biopharma co., LTD.

Recruiting

Dose Escalation Study of Kylo-0603 in Healthy Subjects

Nonalcoholic Steatohepatitis

China
University Health Network, Toronto

Not yet recruiting

Ultra-high Dose Radiation for Liver Metastasis Using MR-guided TReatment With Stereotactic Ablative Single-fraction (ULTRAS)

Liver Metastases
Anhui Provincial Hospital

Not yet recruiting

The Efficacy and Safety of Desensitation Regimen for Patients With High Titers of Anti-HLA Antibodies Prior to Allo-HSCT

High Titers of Anti-HLA Antibody (MFI ≥5000)

China
Al-Azhar University
Sphinx university

Not yet recruiting

The Efficacy of Selenium as an Alternative or Complementary Topical Treatment of Oral Lichen Planus (RCT)

Lichen Planus, Oral

Egypt
Octapharma

Recruiting

Study of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-procedure Preventing of Acute Hereditary Angioedema Attacks

Acute Hereditary Angio Edema

Romania
Kylonova (Xiamen) Biopharma co., LTD.

Not yet recruiting

Single-ascending Dose Study of Kylo-11 in Healthy Subjects

Cardiovascular Diseases

China
Sonoma Biotherapeutics, Inc.

Recruiting

Study of Single Doses of SBT777101 in Subjects With Hidradenitis Suppurativa (Regulate-HS)

Hidradenitis Suppurativa

United States
Tanta University

Not yet recruiting

Different Doses of Dexmedetomidine in External Oblique Intercostal Plane Block in Splenectomy

Dexmedetomidine | Splenectomy | External Oblique Intercostal Plane Block

Egypt
Zhejiang Hanmai Pharmaceutical Technology Co.,...

Not yet recruiting

Multiple-Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of YJ001 for Spray Use in Patients With Diabetic Peripheral Neuropathic Pain

Diabetic Peripheral Neuropathic Pain

United States
The Hong Kong Polytechnic University
The University of Hong Kong

Not yet recruiting

Combination Effect of Optical Defocus and Low Dose Atropine in Myopia Control

Myopia

Hong Kong
Haaglanden Medical Centre
Takeda; Leiden University Medical Center

Not yet recruiting

Complement Inhibition: Attacking the Overshooting Inflammation @Fter Subarachnoid Hemorrhage (CIAO@SAH) (CIAO@SAH)

Subarachnoid Hemorrhage, Aneurysmal
University of Zurich

Recruiting

Ultra Low Dose CT and Use of Iomeron 400 in PCD-CT

Pneumonia | Lung Cancer | Radiation Exposure | Lung Embolism

Switzerland
KARANAHAN

Recruiting

Clinical Study of Personalized Chemotherapy for Breast Cancer With Low Doses of Cyclophosphamide

Stage IV Breast Cancer

Russian Federation
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Study of the Evolution of the Expression of the LAMP-2 Protein During the Advance in Age

Aging

France
M.D. Anderson Cancer Center
Bellicum Pharmaceuticals, Inc.

Not yet recruiting

Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)

Colorectal Cancer | Minimal Residual Disease

United States
AstraZeneca

Recruiting

A Study to Investigate the Pharmacokinetics of Baxdrostat When Given Alone and in Combination With Itraconazole in Healthy Participants

Healthy Participants

United States
Hospital for Special Surgery, New York

Not yet recruiting

Opioid Dispenser for Microdiscectomy/Laminectomy

Pain, Postoperative | Opioid Use | Medical Device | Laminectomy | Diskectomy

United States
Capital Medical University
The Second People's Hospital of Dali Bai Autonomous Prefecture; Wuhu Fourth... and other collaborators

Not yet recruiting

Esketamine Treatment for Depressive Episodes With Suicidal Ideation in Mood Disorders

Mood Disorders | Suicidal Ideation | Depressive Episode
GlaxoSmithKline

Recruiting

A Study to Investigate the Pharmacokinetics of a Combined Oral Contraceptive When Given Alone and in Combination With GSK3036656 in Female Participants of Non-childbearing Potential Aged 18 to 65 Years of Age

Tuberculosis

Spain
Johns Hopkins University
National Center for Complementary and Integrative Health (NCCIH)

Recruiting

Psilocybin in Chronic Low Back Pain and Depression

Depression | Chronic Low-back Pain

United States
Jasper Therapeutics, Inc.

Recruiting

A Dose Escalation Trial of Safety, Pharmacokinetic/Pharmacodynamic and Preliminary Clinical Activity of Briquilimab in Adult Patients With Chronic Inducible Urticaria (CIndU) Who Remain Symptomatic Despite Treatment With H1- Antihistamines (SPOTLIGHT)

Chronic Inducible Urticaria

Germany
University Hospital, Limoges

Not yet recruiting

Evaluation of the Benefits of Administering Immunosuppressive Drugs as Single Daily Doses Over the First Year After Liver Transplantation (EASY) (EASY)

Liver Transplantation | Immunosuppression

France
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Dietary Supplementation and Cognitive Functions in the Elderly (ESPINS)

Cognitive Impairment | Old Age; Debility

Italy
The George Institute
University of Calgary; Berry Consultants

Not yet recruiting

ACT-GLOBAL Adaptive Platform Trial for Stroke (ACT-GLOBAL)

Stroke
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance

Cognitive Impairment | Cannabis Use | Impaired Driving

United States
Boehringer Ingelheim

Recruiting

A Study to Test How Well Different Doses of BI 3034701 Are Tolerated by Healthy Men and People With Overweight or Obesity

Healthy

Germany
Sichuan University

Not yet recruiting

Safety and Tolerability of LDRT Plus Concurrent Partial SBRT and Tislelizumab in Patients With Bulky Tumors

Solid Tumor
Equilibra Bioscience LLC

Recruiting

A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B)

Hemophilia A | Hemophilia B | Healthy Participants

United States
Peking University Third Hospital

Not yet recruiting

A Clinical Pharmacological Study of Dose Halving of Dexamethasone in Pregnant Women With Preterm Labour With Preterm Birth at Greater Than or Equal to 34 Gestational Weeks (34GW+)

Respiratory Distress Syndrome of Newborn
Takeda

Not yet recruiting

A Study of Lanadelumab (Takhzyro) and Icatibant (Firazyr®) in Persons With HAE in China

Hereditary Angioedema (HAE)

China

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