Search clinical trials for: first-line therapy

Total 51850 results

Boston Medical Group

Recruiting

Effectiveness and Safety of TENS Therapy for Premature Ejaculation (TENSPE2)

Premature Ejaculation | TEN | Sex Disorder

Mexico
Hospices Civils de Lyon

Not yet recruiting

Macrohemodynamic Impact of Fluid Removal With Net Ultrafiltration in Patients With Continuous Renal Replacement Therapy

Fluid Overload | Critically Ill | Continuous Renal Replacement Therapy | Fluid Removal

France
Stanford University
American Heart Association

Not yet recruiting

Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries (MVP-ANOCA)

Angina Pectoris | Microvascular Angina | Vasospastic Angina | Myocardial Bridge of Coronary Artery

United States
University Hospital, Rouen

Not yet recruiting

Evaluation of the Influence of Aromatherapy and Music Therapy on Stress During the Management of Cerebral Arteriography (HERMES)

Patients Scheduled for Cerebral Arteriography for Diagnostic or Therapeutic Purposes
Boston Medical Group

Recruiting

Effectiveness of Pelvic Floor Therapy for the Management of Erectile Dysfunction and Premature Ejaculation.

Erectile Dysfunction | Premature Ejaculation | Pelvic Floor; Weak | Premature (Early) Ejaculation

Colombia
Dartmouth-Hitchcock Medical Center
Dartmouth College; University of Massachusetts, Worcester

Not yet recruiting

Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application (SONATA)

Epilepsy | Refractory Epilepsy | Music

United States
Cook Children's Health Care System

Recruiting

Massage Therapy After Thoracic or Lumbar Surgery

Scoliosis; Adolescence | Adolescent Idiopathic Scoliosis, Thoracic Region | Adolescent Idiopathic Scoliosis, Lumbar Region

United States
Ohio State University Comprehensive Cancer Center

Not yet recruiting

A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients

Low Anterior Resection Syndrome | Rectal Carcinoma

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Not yet recruiting

Study of Avelumab and Tuvusertib in Participants With Advanced Urothelial Cancer That Has Progressed on Prior Anti-PD-(L)1 Therapy (JAVELIN DDRiver Bladder)

Urothelial Carcinoma

United States, Germany
Fondation Hôpital Saint-Joseph

Not yet recruiting

Impact of Performing a Rapid Antibiotic Susceptibility Test on Antibiotic Therapy Adaptation in Adult Patients With Enterobacterales Bacteremia (MHR-Blood)

Bacteremia
Beijing Cancer Prevention & Treatment Society
Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Recruiting

A Prospective, Multicenter, Non-interventional, Real-world Study to Characterize Changes in Molecular Markers After Three Weeks of Targeted Therapy With Oxitinib in EGFRm NSCLC (pre-FLAME)

Non Small Cell Lung Cancer

China
Fudan University

Not yet recruiting

Fruquintinib Plus Camrelizumab and HAIC in the Treatment of Non-MSI-H Advanced Colorectal Cancer

Colorectal Cancer

China
Neurona Therapeutics

Not yet recruiting

Effect of NRTX-1001, a Cellular Therapy Product, for the Treatment of Refractory Bilateral TLE

Epilepsy, Temporal Lobe
Ibn Haldun University

Not yet recruiting

The Effectiveness of Transdiagnostic CBT Protocol on Anxiety Disorders

Anxiety Disorders | Generalized Anxiety Disorder | Social Anxiety Disorder | Panic Disorder | Anxiety Disorder NOS

Turkey
Gaffree & Guinle Universitary Hospital
Rio de Janeiro State Research Supporting Foundation (FAPERJ)

Recruiting

Efficacy of Photobiomodulation in the Rehabilitation of Olfactory Dysfunctions Induced by Long COVID-19

COVID-19 | Rehabilitation | Anosmia | Laser Therapy | Ageusia

Brazil
Shanghai Zhongshan Hospital

Not yet recruiting

PD-1/PD-L1 Inhibitors and Anti-angiogenic Therapy Combined With/Without TACE/HAIC in Patients With BCLC B/C Hepatocellular Carcinoma Beyond Up-to-7

Hepatocellular Carcinoma
Adai Technology (Beijing) Co., Ltd.

Recruiting

Digital Cognitive Behavioral Therapy for Depressive Disorders

Depression | Anxiety

China
Çankırı Karatekin University

Recruiting

Comparison of Maternal Role Preparation and Awareness-Centred Occupational Therapy Trainings in Pregnant Women

Pregnancy Related | Postpartum Complication

Turkey
University of Southern California
National Cancer Institute (NCI)

Not yet recruiting

Access to Genetic Testing in Underserved Patients With Cancer

Malignant Solid Neoplasm | Breast Carcinoma | Metastatic Prostate Carcinoma | Ovarian Carcinoma | Triple-Negative Breast Carcinoma | Male Breast Carcinoma | Pancreatic Exocrine Neoplasm | Stage IVB Prostate Cancer American Joint Committee on Cancer v8

United States
Bostal Drug Delivery Co., Ltd

Not yet recruiting

A Study to Evaluate Safety, Tolerability and pK of Semaglutide ER Injectable Suspension in Healthy, Adult Human Subjects

Diabetes Mellitus, Type 2
Rocket Pharmaceuticals Inc.

Not yet recruiting

Clinical Trial to Evaluate the Efficacy of Gene Therapy for Pyruvate Kinase Deficiency

Pyruvate Kinase Deficiency

Spain, United States
Claudia Aristizábal
Sanitas University

Not yet recruiting

Music Therapy Songwriting and Mental Health in Neonatel Intensive Care Unit (NICU) Parents

Mental Health Impairment

Colombia, Poland
Universidad Católica San Antonio de Murcia

Not yet recruiting

Upper Limb Blood Flow Restriction in Handball Players

Sports Physical Therapy

Spain
Takeda

Recruiting

A Study Evaluating Soticlestat in Participants With Dravet Syndrome or Lennox-Gastaut Syndrome Who Have Been Exposed to Fenfluramine

Dravet Syndrome (DS) | Lennox-Gastaut Syndrome (LGS)

United Kingdom, Denmark
Universidad Católica San Antonio de Murcia

Not yet recruiting

Plyometric and Stability Exercise Protocol in Female Basketball Players

Sports Physical Therapy

Spain
AstraZeneca
Premier HealthCare Solutions Inc.

Recruiting

Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on Health Outcomes in Routine Care (ANCHOR)

Asthma

United States
NeuFit - Neurological Fitness and Education

Recruiting

Impact of Direct Current Electrical Stimulation on Treatment of Lumbosacral Radiculopathy

Radiculopathy Lumbar | Radiculopathy Sacral | Radiculopathy Multiple Sites

United States
Chen Xiaoping

Not yet recruiting

Neoadjuvant Therapy in Patients With Resectable HCC Screened by a Multimodal Deep Learning Model

HCC
McGill University

Recruiting

Accuracy of a Continuous Ketone Monitoring (CKM) System in Individuals With Type 1 Diabetes on Insulin Pump Therapy. (CKM 1)

type1diabetes

Canada
First Affiliated Hospital of Fujian Medical University

Not yet recruiting

FAPI and FDG PET/MRI in Diagnosis and Therapy Prediction of Bladder Cancer

Urinary Bladder Neoplasms
King's College Hospital NHS Trust
Chiesi Limited

Not yet recruiting

Less Invasive Surfactant Administration in Late Preterm or Early Term Born Infants

Respiratory Distress Syndrome | Surfactant Deficiency Syndrome Neonatal | Preterm Pregnancy
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Induction Chemoimmunotherapy Combined With Chemoradiotherapy in Esophageal Cancer

Esophageal Cancer | Surgery | Immunotherapy | Chemoradiotherapy | Induction Therapy

China
Peking University Third Hospital
Biotech Pharmaceutical Co., Ltd.

Not yet recruiting

SBRT Combined With Nimotuzumab and Mono-chemotherapy in Locally Advanced Pancreatic Cancer (Nim-PC-28)

Advanced Pancreatic Cancer
Bristol-Myers Squibb

Recruiting

Observational Study in Japanese Patients With Peripheral T-Cell Lymphoma Who Received Second-Line Therapy

Peripheral T-cell Lymphoma

Japan
The Christie NHS Foundation Trust
Royal Marsden NHS Foundation Trust; University College London Hospitals

Not yet recruiting

Investigating the Role of Adjuvant Proton Beam Therapy in Patients With Parotid Carcinoma (PRONTO)

Parotid Cancer
GeneCradle Inc

Recruiting

Evaluation of Safety and Efficacy of Gene Therapy Drug in the Treatment of Spinal Muscular Atrophy (SMA) Type 3 Patients

Spinal Muscular Atrophy Type 3

China
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Descriptive Analysis of Changes in Hepatitis B Markers in People Living With HIV on Injectable Therapy.

Hepatitis B | Hiv Infection

France
Alexandria University

Recruiting

Motivational Enhancement Therapy's Impact on d COPD Outcomes in Geriatric Patient (METgeriatri)

COPD

Egypt
Hebei Medical University Fourth Hospital

Not yet recruiting

Adebrelimab Combined With Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC)

Esophageal Squamous Cell Carcinoma
Cairo University

Not yet recruiting

Post Operative Pain and Oral Health Related Quality of Life Following Pulpotomy VS Extraction of Permanent First Molar

Irreversible Pulpitis

Egypt
Universidad de la Sabana
Universidad de Boyacá; Hospital Universitario de La Samaritana; Universidade...

Not yet recruiting

Maternal Self-efficacy and Motor Development in Premature Infants: Clinical Trial Protocol

Premature Birth | Mothers of Newborn Infants
National Research Center for Hematology, Russia
St. Petersburg State Pavlov Medical University; Federal State Budgetary Institution...

Recruiting

IMPACT-AML: Randomized Pragmatic Clinical Trial for Relapsed or Refractory AML

Refractory Acute Myeloid Leukemia | Early Relapses of Acute Myeloid Leukemia

Russian Federation
Essen Biotech

Not yet recruiting

Sequential CAR-T Cells Therapy for CD5/CD7 Positive T-cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma Using CD5/CD7-Specific CAR-T Cells (BAH246)

T Cell Lymphoma | T Cell Prolymphocytic Leukemia | T-cell Acute Lymphoblastic Leukemia | T Cell Leukemia | T-Cell Lymphoma of CNS | T Cell Childhood ALL

China
Cairo University

Not yet recruiting

Efficacy of High Power Laser Versus Low Level Laser in Ultrasonographic and Functional Outcomes in Patients With Knee Osteoarthritis (OA)

Knee Osteoarthritis
Fundación para la Investigación del Hospital Clínico...

Recruiting

Compression Therapy of the Lower Limbs in Patients With Decompensated Heart Failure

Heart Failure

Spain
The University of Texas Medical Branch, Galveston

Recruiting

Weighted Blanket to Treat Anxiety Related to Trying New Foods the Pediatric Population (Food Anxiety)

Anxiety State | Avoidant Restrictive Food Intake Disorder | Picky Eating | Food Neophobia

United States
Indonesia University

Not yet recruiting

Mobile Apps Enhancing Acupressure Therapy Compliance and Efficacy for Asthenopia

Asthenopia
University of Oxford
Oxford Brookes University; Oxford University Hospitals NHS Trust; Scholar Rock... and other collaborators

Recruiting

Acceptability, Feasibility, Safety and Efficacy of a Optimized Rehabilitation Program for Treated Patients With Spinal Muscular Atrophy (SMA). (ACE SMA)

Spinal Muscular Atrophy

United Kingdom
N.N. Petrov National Medical Research Center of...

Recruiting

High-dose Chemotherapy as Second-line Drug Therapy for Relapsed Germ Cell Tumors (GERMAN)

Germ Cell Tumor

Russian Federation
Bronx VA Medical Center

Not yet recruiting

Dose Optimization of MDMA-Assisted Therapy for PTSD (DosOp)

Posttraumatic Stress Disorder

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