Clinical Trials Sponsored by Royal Free Hospital NHS Foundation Trust

Total 2521 results

Royal Devon and Exeter NHS Foundation Trust

Completed

Trial to Compare Femoral Nerve Block With Local Anaesthetic Injection for Post-operative Pain After Knee Replacement. (LIFT)

Arthritis Knee

United Kingdom
Royal Devon and Exeter NHS Foundation Trust

Withdrawn

Post-void Bladder Scanning in Acute Cauda Equina Syndrome

Polyradiculopathy

United Kingdom
Royal Devon and Exeter NHS Foundation Trust

Completed

Hydrodilatation Versus Arthroscopic Capsular Release for Frozen Shoulder

Frozen Shoulder

United Kingdom
Royal Devon and Exeter NHS Foundation Trust

Completed

Intrathecal Diamorphine Versus Femoral Nerve Block in Primary Total Knee Arthroplasty

Osteoarthritis

United Kingdom
Royal Marsden NHS Foundation Trust
Aventis Pharmaceuticals

Completed

A Phase II Trial Evaluating Irinotecan Plus 5FU/LV in Patients With Relapsed/Refractory Upper GI Tumours

Upper Gastrointestinal Tumours
Royal Brompton & Harefield NHS Foundation Trust
Actelion

Unknown

Bosentan in Pulmonary Hypertension in Interstitial Lung Disease Treatment Study (B-PHIT)

Idiopathic Pulmonary Fibrosis | Pulmonary Hypertension | Interstitial Lung Disease | Nonspecific Interstitial Pneumonia

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
London School of Hygiene and Tropical Medicine; King's College London; King's... and other collaborators

Completed

A Randomised Trial of Expedited Transfer to a Cardiac Arrest Centre for Non-ST Elevation Out-of-hospital Cardiac Arrest (ARREST)

Out-Of-Hospital Cardiac Arrest

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Royal Brompton & Harefield NHS Foundation Trust

Unknown

FIBRotic Interstitial Lung Disease and Nocturnal OXygen (FIBRINOX)

Obstructive Sleep Apnea | Idiopathic Pulmonary Fibrosis | Sleep Disturbance | Sleep Hypoventilation

United Kingdom
University of Sheffield
Sheffield Children's NHS Foundation Trust; Alder Hey Children's Hospital NHS... and other collaborators

Completed

Impact of Parental Perfectionistic Cognitions Self-compassion Intervention Effects on Shame in Child Health Context

Epilepsy | Diabetes Mellitus, Type 1 | Stress | Asthma | Shame | Self-Compassion | Perfectionistic Cognitions

United Kingdom
Royal Marsden NHS Foundation Trust
Imperial College London; Royal Brompton & Harefield NHS Foundation Trust; Royal...

Recruiting

'Lung Health Check' Biomarker Study

Cancer | Lung Cancer

United Kingdom
South Tyneside and Sunderland NHS Foundation Trust
Newcastle-upon-Tyne Hospitals NHS Trust; South Tees Hospitals NHS Foundation... and other collaborators

Completed

ObeSity Related Colorectal Adenoma Risk (OSCAR)

Obesity | Colorectal Cancer | Metabolic Syndrome | Colorectal Neoplasm | Colorectal Adenoma | Liver Fibrosis | Non-Alcoholic Fatty Liver Disease

United Kingdom
Royal Marsden NHS Foundation Trust
Imperial College London; St. George's NHS Foundation Trust

Unknown

Lab-on-a-chip Detection of Cervical Cancer Tumour Markers (MODULAR)

Cervical Cancer
The Leeds Teaching Hospitals NHS Trust
Cambridge University Hospitals NHS Foundation Trust; Nottingham University... and other collaborators

Completed

Hospital Onset Diarrhoea Investigation (HOODINI)

Diarrhea

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Ben Williams Trust

Unknown

Families' Experiences of Paediatric ICC Diagnosis (FEPICCD)

Inherited Cardiac Conditions
Guy's and St Thomas' NHS Foundation Trust
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

Optimisation of Mechanical Insufflation:Exsufflation (MIE2)

Neuromuscular Diseases

United Kingdom
Imperial College Healthcare NHS Trust
Chelsea and Westminster NHS Foundation Trust; Royal Brompton & Harefield NHS...

Completed

Testosterone Patch's Effects on the Cardiovascular System and Libido

Hypoactive Sexual Desire Disorder

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Nottingham University Hospitals NHS Trust; Barts & The London NHS Trust and other collaborators

Recruiting

The BARCODE 2 Study - The Use of Genetic Profiling to Guide Prostate Cancer Treatment (BARCODE2)

Hormone Refractory Prostate Cancer

United Kingdom
Sheffield Hallam University
Chesterfield Royal Hospital NHS Foundation Trust

Not yet recruiting

What Are Persistent Lower Back Pain Patients' Views of Sleep Health Within an Outpatient Musculoskeletal Physiotherapy Setting?

Lower Back Pain | Chronic Low-back Pain | Sleep Disturbance | Persistent Lower Back Pain
Fevzi Shakir

Unknown

Standard Carbon Dioxide Gas Versus Heated Humidified Gas in Gynaecological Laparoscopy

Heated Humidified Carbon Dioxide in Gynaecological Laparoscopic Surgery

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council; The Hillingdon Hospitals NHS Foundation Trust; West...

Completed

Do the SPPB and 4-metre Gait Speed Predict Hospital Readmission in Patients Hospitalised for Acute Exacerbation if COPD?

Respiratory Tract Diseases | Lung Diseases | Disease Progression | Lung Diseases, Obstructive | Pulmonary Disease, Chronic Obstructive | Pulmonary Emphysema | Bronchitis, Chronic

United Kingdom
University of Manchester
Manchester University NHS Foundation Trust; Hull University Teaching Hospitals... and other collaborators

Completed

Saving Babies' Lives Project Impact and Results Evaluation: a Mixed Methodology Study (SPiRE)

Stillbirth

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Brighton and Sussex University Hospitals NHS Trust; Liverpool Heart and Chest...

Completed

Long-term Outcomes in Long Standing Persistent Atrial Fibrillation (LoTO_CASA_AF)

Long Standing Persistent Atrial Fibrillation

United Kingdom
Imperial College London
The Leeds Teaching Hospitals NHS Trust; Norfolk and Norwich University Hospitals... and other collaborators

Completed

Idiopathic Pulmonary Fibrosis Job Exposures Study (IPFJES)

Idiopathic Pulmonary Fibrosis | IPF

United Kingdom
University of Oxford
King's College Hospital NHS Trust; Nottingham University Hospitals NHS Trust; Guy's and St Thomas' NHS Foundation Trust and other collaborators

Enrolling by invitation

Echocardiography: Value and Accuracy at REst and STress (EVAREST)

Coronary Artery Disease | Angina Pectoris | Ischaemic Heart Disease
Royal Brompton & Harefield NHS Foundation Trust
Chelsea and Westminster NHS Foundation Trust; Imperial College Healthcare NHS...

Unknown

Oral Verses Patch Trial In Menopausal Women - Individualisation of Oestrogen Therapy (OPTIMISE)

Venous Thrombosis | Insulin Resistance

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council; The Hillingdon Hospitals NHS Foundation Trust

Terminated

Post-hospitalisation Nutritional Support and Gait Speed in COPD

Respiratory Tract Diseases | Lung Diseases, Obstructive | Pulmonary Disease, Chronic Obstructive | Pulmonary Emphysema | Bronchitis, Chronic

United Kingdom
AJAY YERRAMASU
Royal Free Hospital NHS Foundation Trust; Barnet and Chase Farm Hospitals NHS... and other collaborators

Unknown

Role of Cardiac CT in Rapid Access Chest Pain Clinics (RADICAL) (RADICAL)

Coronary Artery Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
British Heart Foundation

Completed

Programme to Optimise Risk Factors in Patients Waiting for Coronary Artery Bypass Surgery

Coronary Artery Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
AHEPA University Hospital

Completed

a-Klotho in Relation to Calcification in the Coronary Arteries and Aortic Valve in Patients With Chronic Kidney Disease

Chronic Kidney Diseases | Vascular Calcification
Royal Brompton & Harefield NHS Foundation Trust
University Hospital Tuebingen

Terminated

Evaluating Additional Platelet Inhibition in Patients With High Platelet Reactivity Undergoing Percutaneous Coronary Intervention (APACS-HPR)

Cardiovascular Disease | Acute Coronary Syndrome

Germany
AHEPA University Hospital
Royal Brompton & Harefield NHS Foundation Trust

Completed

Post-operative Thoracic Epidural Analgesia and Incidence of Major Complications: a Large Retrospective Dual Center Experi-ence

Chronic Pain | Thoracic Cancer | Neuropathic Pain

Greece
Royal Devon and Exeter NHS Foundation Trust
Derriford Hospital

Completed

Video Laryngoscopy in Newborn Babies V1

Respiratory Distress Syndrome

United Kingdom
Royal United Hospitals Bath NHS Foundation Trust
University of Bath; Great Western Hospitals NHS Foundation Trust

Recruiting

Development of a Drill Guidance System to Aid Intra-operative Surgical Drilling

Orthopaedic Surgery

United Kingdom
Chelsea and Westminster NHS Foundation Trust
Royal Brompton & Harefield NHS Foundation Trust; British Heart Foundation

Unknown

Early Cardiac Computed Tomography (CT) In Patients Admitted With Acute Chest Pain (EXACCT)

Acute Chest Pain

United Kingdom
Nottingham University Hospitals NHS Trust
Northern Care Alliance NHS Foundation Trust; Barts & The London NHS Trust; University... and other collaborators

Not yet recruiting

Neurological Recovery Following NOS-SACD

Paresthesia | Neurologic Symptoms | B12 Deficiency Vitamin | Nitrous Oxide Abuse | Subacute Combined Cord Degeneration
Royal National Orthopaedic Hospital NHS Trust

Recruiting

Feasibility and Acceptability of Collaborative Care for People With Musculoskeletal and Mental Problems (CCOPER)

Musculoskeletal Diseases | Mental Disorder

United Kingdom
The Royal Orthopaedic Hospital NHS Trust

Completed

The Experiences of Patients With Greater Trochanteric Pain Syndrome.

Greater Trochanteric Pain Syndrome

United Kingdom
The Royal Orthopaedic Hospital NHS Trust

Completed

Acellular Dermis in Rotator Cuff Repair

Rotator Cuff Injuries | Rotator Cuff Tears

United Kingdom
Royal National Orthopaedic Hospital NHS Trust

Unknown

Musculoskeletal Imaging of Runners

Musculoskeletal Injury

United Kingdom
Papworth Hospital NHS Foundation Trust
Cambridge University Hospitals NHS Foundation Trust

Not yet recruiting

Validation of UK Protocols to Exclude Brain Blood Flow During Normothermic Regional Perfusion (NRP)

Cerebral Blood Flow
Moorfields Eye Hospital NHS Foundation Trust
Brighton and Sussex University Hospitals NHS Trust; University Hospitals Bristol... and other collaborators

Completed

Multicentre Randomised Clinical Trial Comparing Fixed vs Pro re Nata (PRN) Dosing of 700 μg Dexamethasone (OZDRY)

Diabetic Macular Edema

United Kingdom
University of Cambridge
Guy's and St Thomas' NHS Foundation Trust; Manchester University NHS Foundation... and other collaborators

Completed

Observational Cohort Study of a National Extracorporeal Membrane Oxygenation Service for Adults With Respiratory Failure: the NHS ECMO Study. (NHS ECMO)

Acute Respiratory Failure
Royal National Orthopaedic Hospital NHS Trust

Unknown

Blood Titanium Analysis of Patients With MAGEC Spine Rods in the COVID-19 Environment

MAGEC Rod

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Heidelberg University; Chelsea and Westminster NHS Foundation Trust

Withdrawn

EBUS-TBNA Versus EBUS-TBNB

Lymphoma | Carcinoma | Sarcoidosis | Mediastinal Lymphadenopathy | Hilar Lymphadenopathy | Mycobacterial Disease

United Kingdom, Germany
East and North Hertfordshire NHS Trust
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Assessment of Thrombotic Status in Patients With Atrial Fibrillation

Atrial Fibrillation
University of Oxford
Oxford University Hospitals NHS Trust; South Central Ambulance Service NHS... and other collaborators

Completed

Computer Assisted Lessening of Intrusive Memories in the Emergency Department (CALM-ED)

Post Traumatic Stress Disorder

United Kingdom
The Royal Orthopaedic Hospital NHS Trust

Recruiting

Patient Specific Guides and Surgical Planning for Periacetabular Osteotomy; Post Marketing Evaluation Study (MyPAO)

Acetabular Dysplasia | Periacetabular Osteotomy | Pelvic Osteotomy

United Kingdom
The Royal Orthopaedic Hospital NHS Trust

Completed

Protocol of Accelerated Rehabilitation Following Surgical Correction of Adolescent Idiopathic Scoliosis (PARIS)

Scoliosis Idiopathic

United Kingdom
Royal National Orthopaedic Hospital NHS Trust

Terminated

To Compare Conservative Management Vs. Balloon Kyphoplasty in the Treatment of VCFs in Patients With Multiple Myeloma (MELODY)

Multiple Myeloma

United Kingdom
University of Southampton
Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust; Southern...

Completed

Treatment Burden in Parkinson's

Parkinson Disease | Parkinson

United Kingdom

Clinical Trials Sponsored by Royal Free Hospital NHS Foundation Trust

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