Search clinical trials for: First in man

Total 467944 results

Jiangsu Simcere Pharmaceutical Co., Ltd.
Shanghai Xianxiang Medical Technology Co., Ltd.; Simcere Zaiming

Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of SIM0237 in Adult Participants With Advanced Solid Tumors

Locally Advanced Unresectable or Metastatic Solid Tumor

United States, China
First Affiliated Hospital of Zhejiang University
Zhejiang University; Huzhou Third People's Hospital; Wenzhou Seventh People's... and other collaborators

Recruiting

Early Identification of TRD and Construction and Clinical Validation of NTBS Precision Technology

Treatment-Resistant Depression

China
The Affiliated Nanjing Drum Tower Hospital of Nanjing...
Xian-Janssen Pharmaceutical Ltd.

Not yet recruiting

Adjutant Apalutamide Plus ADT in Post-RP Patients With High Risk of Recurrence (ARES Study) (ARES)

Prostate Cancer | Biochemical Recurrence | High Risk

China
Sun Yat-sen University

Recruiting

Efficacy and Safety of Triweekly Cetuximab in Combination With Capecitabine as First-line Maintenance Treatment for KRAS/BRAF Wild-type Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

China
Keymed Biosciences Co.Ltd

Recruiting

Clinical Study of CM338 in the Treatment of Immunoglobulin A Nephropathy

IgA Nephropathy

China
Jianhua Zhou
LinkDoc Technology (Beijing) Co. Ltd.

Recruiting

The Efficacy and Safety of Prednisone Combined With Huaiqihuang Granule for Primary Nephrotic Syndrome in Children

Nephrotic Syndrome in Children

China
Lili Jia

Recruiting

Advanced Analgesia on the Quality of Recovery After General Anesthesia in Elderly Patients

General Anesthetics，Emergence Agitation

China
Scorpion Therapeutics, Inc.

Recruiting

First-in-Human Study of STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

Breast Cancer | Gynecologic Cancer | HNSCC | Solid Tumors, Adult

United States, Spain, France, Italy
Neuronostics Ltd

Recruiting

A Prospective Diagnostic Belief Updating Study to verIfy the Utility of BioEP in First Seizure Clinics. (PRISTINE)

Epilepsy

United Kingdom
Children's Hospital of Fudan University
First Affiliated Hospital, Sun Yat-Sen University; Shandong Provincial Hospital and other collaborators

Recruiting

Effects of Traditional Chinese Medicine (GSJYF) in Children With Inherited Proteinuric Kidney Disease

Kidney Diseases | Proteinuria | Hereditary Nephropathy

China
Janssen Research & Development, LLC
Bristol-Myers Squibb

Recruiting

A Study of Milvexian Versus Apixaban in Participants With Atrial Fibrillation (LIBREXIA-AF)

Atrial Fibrillation

United States, Belgium, Italy, Japan, Taiwan, South Africa, Korea, Republic of, Poland, Chile, Serbia, Israel, France, Netherlands, Denmark, Hungary, Argentina, Australia, China, Spain, New Zealand, Czechia, Bulgaria, Croatia, Malaysia, German... and more
Janssen Research & Development, LLC
Bristol-Myers Squibb

Recruiting

A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome (LIBREXIA-ACS)

Acute Coronary Syndrome

United States, Taiwan, Korea, Republic of, Italy, South Africa, Belgium, Argentina, Israel, Malaysia, Romania, Serbia, China, Australia, Netherlands, United Kingdom, Denmark, Czechia, Hungary, Japan, France, Canada, Bulgaria, Spain, T... and more
Incyte Corporation

Recruiting

A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN) (TRuE-PN1)

Prurigo

United States, Spain, France, Poland, Germany, Belgium, Netherlands, Argentina, Canada, Chile, Italy, Brazil
Peking University Sixth Hospital
Peking University First Hospital; Sichuan Provincial People's Hospital; Shenzhen... and other collaborators

Recruiting

Software-delivered CBT-I for Insomnia Disorder

Insomnia Disorder

China
Shanghai Hengrui Pharmaceutical Co., Ltd.

Recruiting

Phase Ⅱ Study of Intercostal Nerve Block With HR18034 for Postsurgical Pain Management

Thoracoscopic Lobectomy

China
Spanish Breast Cancer Research Group
AstraZeneca

Recruiting

Trastuzumab Deruxtecan in First-line HER2-positive Locally Advanced/MBC Patients Resistant to Trastuzumab+Pertuzumab (TRANSCENDER)

Metastatic Breast Cancer | Locally Advanced Breast Cancer

Spain
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Recruiting

A Study to Evaluate Treatment Preferences for Japanese Participants With Muscle-invasive Urothelial Carcinoma of the Bladder (SNUGGLE)

Urinary Bladder Neoplasms

United States
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Registry Study for Optimal Management of Liver Failure in the Chinese Population (RESOLVE-C)

Liver Failure

China
Amgen

Recruiting

Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancer (DeLLphi-304)

Small Cell Lung Cancer (SCLC)

China, United States, Australia, Netherlands, Taiwan, Spain, Canada, Korea, Republic of, Turkey, Israel, Austria, Japan, France, United Kingdom, Germany, Belgium, Denmark, Czechia, Switzerland, Italy, Hungary, Ireland, Argentina, Brazil, Malays... and more
Ironwood Pharmaceuticals, Inc.

Recruiting

A Phase 2 Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome

Interstitial Cystitis | Bladder Pain Syndrome

United States
Eli Lilly and Company

Recruiting

A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease (TRAILBLAZER-ALZ 6)

Mental Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Neurocognitive Disorders | Neurodegenerative Diseases | Dementia | Alzheimer's Disease

United States, United Kingdom
Eli Lilly and Company

Recruiting

A Study to Assess the Long-Term Safety and Efficacy of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis (ADorable-2)

Eczema | Atopic Dermatitis

United States, Taiwan, Spain, Mexico, Japan, Brazil, Australia, Canada, Czechia, France, Germany, Argentina, Poland
RemeGen Co., Ltd.

Recruiting

Study of Telitacicept in Generalized Myasthenia Gravis

Myasthenia Gravis, Generalized

China
Byondis B.V.

Recruiting

First-in-human Dose Escalation and Expansion Study With the SIRPα-directed Monoclonal Antibody BYON4228

Lymphoma

Spain, United Kingdom, Netherlands, Italy
Biocad

Recruiting

A Clinical Study of BCD-217 (Nurulimab + Prolgolimab) Followed by Anti-PD-1 Compared to Anti-PD-1 Monotherapy as First-Line Treatment in Subjects With Unresectable/Metastatic Melanoma (OCTAVA)

Melanoma | Melanoma (Skin) | Melanoma Stage IV | Melanoma Stage III | Melanoma Metastatic | Melanoma Unresectable | Melanoma Advanced

India, Russian Federation, Belarus
Shanghai Unicar-Therapy Bio-medicine Technology...
The First Affiliated Hospital of Soochow University

Recruiting

PD-1 Silent PSMA/PSCA Targeted CAR-T for the Treatment of Prostate Cancer

Prostate Cancer

China
Biocad

Recruiting

Efficacy and Safety of Divozilimab in Patients With Neuromyelitis Optica Spectrum Disorders (AQUARELLE) (AQUARELLE)

Neuromyelitis Optica Spectrum Disorders

Russian Federation
Hangzhou Dinova EP Technology Co., Ltd

Recruiting

First in Man Study of Left Atrial Appendage Pulsed Field Ablation Occluder

Nonvalvular Atrial Fibrillation

China
Yu jiren

Recruiting

Perioperative Chemotherapy Plus Toripalimab for dMMR Locally Advanced Gastric or Esophagogastric Junction Adenocarcinoma

Adenocarcinoma of the Stomach | Mismatch Repair Deficiency | Adenocarcinoma of Esophagogastric Junction

China
Dr. Gavin Winston
Canadian Institutes of Health Research (CIHR); Nova Scotia Health Authority

Recruiting

Seizure Recurrence After Unprovoked First Seizure

Epilepsy | Single Seizure

Canada
Second Affiliated Hospital, School of Medicine,...
Shaoxing People's Hospital; Shaoxing Second Hospital; Huizhou Municipal Central... and other collaborators

Recruiting

Ixazomib Plus Low-dose Lenalidomide Versus Ixazomib Alone for Maintenance Treatment of High Risk Multiple Myeloma

Multiple Myeloma

China
Second Affiliated Hospital, School of Medicine,...
The First Affiliated Hospital of Zhejiang Chinese Medical University; Hangzhou... and other collaborators

Not yet recruiting

MG Granules Improve COVID-19 Efficacy and Safety of Convalescent Exercise Tolerance

COVID-19
Su Guohai
Shandong First Medical University

Recruiting

A Cohort of Patients Undergoing Percutaneous Coronary Intervention (APCIcohort)

Myocardial Infarction | Acute Coronary Syndrome | Percutaneous Coronary Intervention | Unstable Angina

China
Xiaoyan Jia

Recruiting

Neutrophil Gelatinase-associated Lipocalin VS Vascular Calcification in Maintenance Hemodialysis Patients (NGAL)

Chronic Kidney Disease-Mineral and Bone Disorder

China
Institute of Hematology & Blood Diseases Hospital...
Henan Cancer Hospital; Beijing Children's Hospital; Tianjin Medical University... and other collaborators

Recruiting

TPO-RAs Combining Anti-CD 20 Monoclonal Antibody Versus TPO-RAs in the Management of Pediatric Primary Immune Thrombocytopenia (ITP)

Primary Immune Thrombocytopenia (ITP)

China
Guangzhou Lupeng Pharmaceutical Company LTD.

Recruiting

A Study of LP-168 in Participants With Relapse or Refractory Mantle Cell Lymphoma

Mantle Cell Lymphoma (MCL)

China
Xinjiang Medical University
First Affiliated Hospital of Xinjiang Medical University

Recruiting

Renal Denervation in Patients With Chronic Heart Failure With Preserved Ejection Fraction (RDN-HFPEF)

Heart Failure With Preserved Ejection Fraction | Renal Denervation

China
Janssen Research & Development, LLC

Recruiting

A Study of TAR-200 in Combination With Cetrelimab or TAR-200 Alone Versus Intravesical Bacillus Calmette-Guérin (BCG) in Participants With BCG-naïve High-risk Non-muscle Invasive Bladder Cancer (HR-NMIBC) (SunRISe-3)

Bladder Cancer

United States, Belgium, Korea, Republic of, Italy, Taiwan, China, United Kingdom, Germany, France, Argentina, Brazil, Poland, Spain, Czechia, Japan, Netherlands, India, Canada, Mexico, Australia, Portugal
I.M. Sechenov First Moscow State Medical University

Recruiting

Optimization of Total Knee Arthroplasty Using Robotic Systems

Knee Osteoarthritis

Russian Federation
Lisata Therapeutics, Inc.

Recruiting

A Study of LSTA1 When Added to Standard of Care Versus Standard of Care Alone in Patients With Advanced Solid Tumors (BOLSTER)

Cholangiocarcinoma | Bile Duct Cancer | Intrahepatic Cholangiocarcinoma | Gallbladder Carcinoma | Gallbladder Cancer | Gall Bladder Cancer | Extrahepatic Cholangiocarcinoma | Gall Bladder Carcinoma

United States, Spain
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Use of BRAF-Targeted Therapy After Surgery and Usual Chemotherapy for BRAF-Mutated Colon Cancer

Stage III Colon Cancer AJCC v8 | Colon Adenocarcinoma | Microsatellite Stable Colon Carcinoma | Stage IIB Colon Cancer AJCC v8 | Stage IIC Colon Cancer AJCC v8

United States
BeiGene

Recruiting

A Study to Evaluate the Safety and Efficacy of Zanubrutinib in Participants With Primary Membranous Nephropathy

Primary Membranous Nephropathy

China, United Kingdom, United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

A Multicenter Randomized Controlled Study of Pulse Magnetotherapy Combined Medication in Anxiety Combined With Insomnia

Insomnia | Anxiety Disorder

China
NRG Oncology
National Cancer Institute (NCI); Alliance for Clinical Trials in Oncology; Eastern... and other collaborators

Recruiting

Testing Radiation and HER2-targeted Therapy Versus HER2-targeted Therapy Alone for Low-risk HER2-positive Breast Cancer (HERO)

HER2-positive Breast Cancer

United States, Puerto Rico
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Airway Management During Deep Sedation in Hysteroscopy

Deep Sedation

China
Janssen Research & Development, LLC
Bristol Myers Squibb Company (BMS)

Recruiting

A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE (LIBREXIA-STROK)

Ischemic Stroke; Ischemic Attack, Transient

Italy, United States, Hong Kong, Japan, Taiwan, South Africa, Korea, Republic of, Israel, United Kingdom, Argentina, Belgium, New Zealand, Canada, Germany, Czechia, Denmark, Mexico, Croatia, France, Australia, Brazil, China, Hungary, ... and more
The First Affiliated Hospital with Nanjing Medical...
National Natural Science Foundation of China

Not yet recruiting

Anticoagulation Using Rivaroxaban on Top of Aspirin in Intracranial Atherosclerotic Stenosis (AA-ICAS)

Ischemic Stroke | Stenosis | Intracranial Atherosclerosis
The University of Texas Health Science Center,...

Recruiting

Randomized Trial of Enteral Vitamin D Supplementation in Infants < 28 Weeks Gestational Age or <1000 Grams Birth Weight

Vitamin D Deficiency

United States
AstraZeneca
Parexel

Recruiting

A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA) (DOMINICA)

Asthma

Korea, Republic of, Spain, United States, Argentina, France, Italy, Taiwan, Germany, United Kingdom, Poland, Canada
AstraZeneca

Recruiting

Phase III, Open-label, First-line Study of Dato-DXd in Combination With Durvalumab and Carboplatin for Advanced NSCLC Without Actionable Genomic Alterations (AVANZAR)

NSCLC

China, United States, United Kingdom, Korea, Republic of, Italy, Hungary, Spain, Vietnam, France, Brazil, Canada, Japan, Taiwan, Germany, Austria, Turkey, India, Peru, Poland, Sweden, Bulgaria, Greece, Mexico, Denmark

Search clinical trials for: First in man

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