Search clinical trials for: biologic,

Total 540 results

Stanford University

Active, not recruiting

Radical-Dose Image Guided Radiation Therapy in Treating Patients With Metastatic Non-small Cell Lung Cancer Undergoing Immunotherapy

Stage IV Non-Small Cell Lung Cancer

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Collection and Analysis of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers

Healthy Volunteers

United States
National Cancer Institute, Naples
Mario Negri Institute for Pharmacological Research

Active, not recruiting

Bevacizumab Beyond Progression in Platinum Sensitive Ovarian Cancer (MITO16MANGO2b)

Recurrent Ovarian Cancer

France, Italy, Switzerland, Monaco, Greece
National Institute of Arthritis and Musculoskeletal...

Completed

Monoclonal Antibody Treatment for Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States
Joshua Zeichner
Astellas Pharma Inc

Terminated

A Pilot Study of Alefacept for the Treatment of Pityriasis Rubra Pilaris

Pityriasis Rubra Pilaris

United States
Helsinki University Central Hospital
Foundation for Paediatric Research, Finland; Päivikki and Sakari Sohlberg Foundation... and other collaborators

Completed

Aggressive Combination Drug Therapy in Very Early Polyarticular Juvenile Idiopathic Arthritis (ACUTE-JIA)

Juvenile Idiopathic Arthritis

Finland
Centocor, Inc.

Completed

A Study of the Safety and Efficacy of Ustekinumab (CNTO 1275) in Participants With Crohn's Disease

Crohn Disease

United States, Canada, Belgium
The University of Texas Health Science Center,...
CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCES

Recruiting

BIOlogic Augmented Repair of Complex Anal Fistula Using Acellular Matrix and/or Autologous Platelet-rich Plasma (BIO RAMP)

Anal Fistula

United States
Aeris Therapeutics

Withdrawn

Phase 3 Study of the Biologic Lung Volume Reduction (BLVR) System in Advanced Upper Lobe Predominant (ULP) Emphysema

Advanced Upper Lobe Predominant Emphysema
James Stannard

Completed

A Biologic Joint Replacement Strategy to Treat Patients With Severe Knee Trauma and Post-Traumatic Knee Osteoarthritis

Post-traumatic Osteoarthritis

United States
Celgene Corporation

Terminated

Study to Determine the Optimal Biologic Dose of CC-401 in Subjects With High-Risk Myeloid Leukemia

Myeloid Leukemia

United States
St. Petersburg Research Institute of Vaccines and...

Completed

Tolerability, Safety and Immunogenicity Trial of the Flu-M Quadro, Tetravalent Inactivated Split Influenza Vaccine

Vaccine Reaction | Influenza | Influenza, Human | Vaccination; Infection | Influenza Viral Infections

Russian Federation
Cancer Research UK

Terminated

Boron Phenylalanine With or Without Mannitol in Treating Patients With Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United Kingdom
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
First Affiliated Hospital Bengbu Medical College

Completed

Recombinant Omicron-Delta COVID-19 Vaccine (CHO Cell)

COVID-19

China
National Cancer Institute (NCI)

Enrolling by invitation

Prospective Procurement of Tumor Tissue to Identify Novel Therapeutic Targets and Study the Tumor Microenvironment

Melanoma | Pancreatic Cancer | Lung Cancer | Solid Tumors | Gastrointestinal Cancer | Hematologic Malignancy | Liver Cancer | Pre-Malignancy

United States
Universidade Nova de Lisboa

Completed

Biomarkers Identification of Anti-tumor Necrosis Factor (TNF) α Agent's Efficacy in Ankylosing Spondylitis Patients

Ankylosing Spondylitis

Portugal
Bausch Health Americas, Inc.

Completed

A Study of Brodalumab (SILIQ®) in Psoriasis Participants With Inadequate Response to Their Current Biologic Agent Regimen

Psoriasis

Canada
University of Pittsburgh
LEO Pharma

Completed

A Study to Determine the Efficacy of Taclonex Topical Suspension as a Supplement to Non-biologic Systemic Therapy

Psoriasis

United States
Seoul National University Hospital

Recruiting

Korean College of Rheumatology Biologics and Targeted Therapy Registry (KOBIO)

Rheumatoid Arthritis | Psoriatic Arthritis | Ankylosing Spondylitis

Korea, Republic of
Baxter Healthcare Corporation
Synovis Surgical Innovations

Terminated

Veritas in Non-Bridging Ventral Hernia Repair (VIBE)

Hernia

United States
Shanghai Virogin Biotech Co., Ltd.

Recruiting

A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Biologic Effect of VG2025 in Patients With Solid Tumors

Advanced Malignant Solid Tumor

China
Yonsei University

Not yet recruiting

Efficacy and Safety of Vedolizumab in Biologic-naïve Korean Patients With Moderate to Severe Inflammatory Bowel Disease (VEDOKO-IIT)

Crohn's Disease and Ulcerative Colitis

Korea, Republic of
Hoffmann-La Roche

Completed

A Study of Tocilizumab in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to Current Non-Biologic DMARDs

Rheumatoid Arthritis

Finland
University Health Network, Toronto
The Leukemia and Lymphoma Society

Completed

Study Evaluating the Tolerance and Biologic Activity of Oral Ciclopirox Olamine in Patients With Relapsed or Refractory Hematologic Malignancy

Acute Myeloid Leukemia | Chronic Lymphocytic Leukemia | Acute Lymphocytic Leukemia | Hematologic Malignancy | Chronic Myelogenous Leukemia | Myelodysplasia | Hodgkin's Disease

Canada
Rambam Health Care Campus
Technion, Israel Institute of Technology

Unknown

The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin (RING UB LIGASE)

Group 1: Trauma Operation for Otherwise Healthy Patients | Group 2: Primary Tumors of Mesenchymal Origin

Israel
Bristol-Myers Squibb

Completed

Economic Burden in Adult Patients Diagnosed With Rheumatoid Arthritis (RA) Receiving Treatment With Biologic Disease-modifying Antirheumatic Drugs (bDMARDs)

Rheumatoid Arthritis
Boehringer Ingelheim

Terminated

Nintedanib (BIBF 1120) in Mesothelioma

Mesothelioma

United States, Spain, Canada, United Kingdom, Belgium, Czechia, Sweden, Australia, Germany, Italy, Japan, Russian Federation, Israel, Poland, France, Netherlands, Austria, Mexico, Portugal, Egypt, Argentina, Croatia, Chile, Denmark, Norway and more
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Collection of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Laboratory Research Studies

Healthy Volunteers

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Systemically Administered Hydrocortisone on the Immune System in Healthy Volunteers

Healthy | Healthy Subjects | Immunosuppression

United States
Cumberland Pharmaceuticals

Terminated

A Phase 3 Telavancin Staphylococcus Aureus (S. Aureus) Bacteremia Trial

Bacteremia

United States
Georg Aue, M.D.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Lenalidomide in Previously Treated Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Chronic Lymphocytic Leukemia (CLL) | Small Lymphocytic Lymphoma

United States
National Cancer Institute (NCI)

Recruiting

Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation

Bronchiolitis Obliterans Syndrome | Chronic Graft vs Host Disease | Chronic Graft-Versus-Host Disease

United States
Wageningen University and Research

Completed

Exploring the Potential of Finger Prick Blood for Assessment of BIOmarkers for LOw Grade Inflammation and CVD Risk (BIOLOGIC)

Biomarker

Netherlands
Argos Therapeutics

Completed

Study Testing the Biologic Activity and Safety of an Immunotherapeutic in Patients With Newly Diagnosed Stage IV Kidney Cancer

Renal Cell Carcinoma

Canada, United States
Mashhad University of Medical Sciences
Roche Pharma AG

Completed

Low Dose Rituximab as a First Line Biologic Therapy for the Treatment of DMARD Resistant Patients With Rheumatoid Arthritis

DMARD Resistant Rheumatoid Arthritis

Iran, Islamic Republic of
Biologics & Biosimilars Collective Intelligence...
Henry Ford Health System; HealthPartners Institute; Amgen; Aetna, Inc.; Harvard Pilgrim... and other collaborators

Completed

Descriptive Analysis of G-CSF Use in Patients With Breast Cancer, Lung Cancer, or Lymphoma Treated

Breast Cancer | Lung Cancer
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Recruiting

Molecular Predictors of Cancer in Patients at High Risk of Lung Cancer

Lung Cancer

United States
Sabine Dieperink
University of Copenhagen; University of Aarhus; Statens Serum Institut

Completed

Bloodstream Infections in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis | Staphylococcus Aureus Bacteremia
Pfizer

Completed

Study to Evaluate Safety and Effects of Tofacitinib and Biologic Disease Modifying Antirheumatic Drugs in People Treated for Rheumatoid Arthritis

Arthritis, Rheumatoid

Japan
Bristol-Myers Squibb

Completed

A Study to Determine the Risk of Cancer in Rheumatoid Arthritis (RA) Patients Who Use Abatacept and Other Biologic Agents

Rheumatoid Arthritis

United States
Hoffmann-La Roche

Completed

A Retrospective, Observational Chart Review of Biologics in Monotherapy Versus the Combination Biologic Plus Methotrexate in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

United Kingdom
National Institute of Allergy and Infectious Diseases...

Completed

Daclizumab to Treat Wegener's Granulomatosis

Wegener's Granulomatosis

United States
National Cancer Institute (NCI)

Completed

LMB-2 to Treat Hairy Cell Leukemia

Hairy Cell Leukemia

United States
Zimmer Orthobiologics, Inc.

Completed

Post Market Study of DeNovo NT, Natural Tissue Graft

Cartilage Repair

United States
University of Crete

Recruiting

Role of Epithelial Barrier Integrity in Biologic Treatment Response of Severe Asthmatics With/Out Chronic Rhinosinusitis With Nasal Polyps (CRSwNP).

Severe Eosinophilic Asthma w/wo CRSwNP

Greece
U.S. Army Medical Research and Development Command
The PATH Malaria Vaccine Initiative (MVI)

Withdrawn

A Phase I Clinical Trial Immunizing Healthy Adults With the NMRC-M3V-Ad-PfCA Vaccine to Generate Biologic Reagents (AdBa)

Healthy | Malaria

United States
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Hunan Provincial Center for Disease Control and Prevention

Not yet recruiting

Omicron BA.4/5-Delta COVID-19 Vaccine Phase I Clinical Trial

COVID-19
Vanderbilt University Medical Center
National Cancer Institute (NCI)

Recruiting

Gastrointestinal Biomarkers in Tissue and Biological Fluid Samples From Colorectal Cancer Patients

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Precancerous Condition

United States
University of California, Irvine

Withdrawn

Evaluation of Vitamin D Levels in Psoriasis Patients

Psoriasis

United States
National Cancer Institute (NCI)

Active, not recruiting

Development of a Biologic Specimen Bank for the Study of Early Markers of Lung Cancer Among Tin Miners in Yunnan, China

Lung Cancer

China

Search clinical trials for: biologic,

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Burundi

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations