Search clinical trials for: bleeding risk, acute coronary syndrome, platelet agregation,

Total 41307 results

Sanofi

Completed

Study of Otamixaban Versus Unfractionated Heparin (UFH) and Eptifibatide in Non-ST Elevation Acute Coronary Syndrome (SEPIA-ACS1)

Coronary Disease

United States, France, Brazil, Poland, Romania, Russian Federation, Germany, Italy, Netherlands, Portugal, Spain, Switzerland, Turkey, Bulgaria, India, Malaysia, Singapore, Slovakia, Taiwan, Czech Republic, Mexico, Argentina, Croatia, Austri... and more
University of Pecs

Completed

Prasugrel Versus Clopidogrel to TREAT High Platelet Reactivity (TREAT-HPR)

Acute Coronary Syndrome

Hungary
Biotronik France
European Cardiovascular Research Center; Allies in Cardiovascular Trials Initiatives...

Completed

Genotyping Infarct Patients to Adjust and Normalize Thienopyridine Treatment (GIANT)

Coronary Artery Disease | Acute Coronary Syndrome | Genetic Resistance to Clopidogrel | Compliance to Thienopyridine Treatment

France
Shenyang Northern Hospital

Completed

BivaliRudin in Acute Myocardial Infarction vs Glycoprotein IIb/IIIa and Heparin :a Randomised Controlled Trial. (BRIGHT)

Percutaneous Coronary Intervention | Acute Myocardial Infarction

China
Fundación Pública Andaluza para la gestión de la...
Andaluz Health Service

Completed

VERifynow in DIabetes Non-responsiveness: a Study on Switching From Clopidogrel to Prasugrel (VERDI)

Acute Coronary Syndrome | Diabetes Mellitus Type II

Spain
Royal Brompton & Harefield NHS Foundation Trust
University Hospital Tuebingen

Terminated

Evaluating Additional Platelet Inhibition in Patients With High Platelet Reactivity Undergoing Percutaneous Coronary Intervention (APACS-HPR)

Cardiovascular Disease | Acute Coronary Syndrome

Germany
Johnson & Johnson Pharmaceutical Research & Development...
Bayer

Completed

An Efficacy and Safety Study for Rivaroxaban in Patients With Acute Coronary Syndrome

Myocardial Infarction | Myocardial Ischemia | Acute Coronary Syndrome | Unstable Angina

United States, France, Poland, Ukraine, United Kingdom, China, Belgium, Germany, Spain, Argentina, Chile, Colombia, Israel, Mexico, Portugal, Bulgaria, India, Malaysia, Romania, Russian Federation, Serbia, Turkey, Korea, Republic of, ... and more
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Positive Psychology to Improve Cardiac Health Behaviors (PEACE)

Acute Coronary Syndrome | Emotions | Patient Compliance

United States
Italian Society of Invasive Cardiology
Eustrategy

Unknown

Customized Choice of Oral P2Y12 Receptor Blocker (PRU-MATRIX)

Acute Coronary Syndrome | Coronary Angioplasty

Italy
Assistance Publique Hopitaux De Marseille

Completed

Evaluation of Ticagrelor Anti Platelet and Pleiotropic Effects in Patients Undergoing Percutaneous Coronary Intervention for an Acute Coronary Syndrome

Acute Coronary Syndrome

France
University of Zagreb
Clinical Hospital Centre Zagreb; Ministry of Science, Education and Sport,...

Completed

Continuous Clopidogrel Dose Adjustment in Acute Coronary Syndrome Patients With High On-treatment Platelet Reactivity

Acute Coronary Syndrome

Croatia
Medstar Health Research Institute

Unknown

African-American Pharmacogenetics (AA Genetic)

Acute Coronary Syndrome

United States
RenJi Hospital

Unknown

Efficacy of Ticagrelor vs Clopidogrel in High-risk NSTE-ACS Patients Undergoing Early PCI

Acute Coronary Syndrome

China
AstraZeneca

Completed

Study to Assess Safety and Efficacy of Ticagrelor (AZD6140) Versus Clopidogrel in Asian/Japanese Patients With Non-ST or ST Elevation Acute Coronary Syndromes (ACS)

Acute Coronary Syndrome | Percutaneous Coronary Intervention

Korea, Republic of, Japan, Taiwan
Dexa Medica Group

Completed

Efficacy of DLBS1033 in Patients With Acute Ischemic Stroke

Acute Ischemic Stroke

Indonesia
Massachusetts General Hospital
AstraZeneca

Withdrawn

Effect of Pretreatment With Ticagrelor on Residual Thrombus After PCI in Patients Presenting With ACS in Comparison With Delayed Treatment at the Time of PCI: an OCT Study

Coronary Artery Disease | Acute Coronary Syndrome

United States
The Medicines Company

Terminated

A Clinical Trial to Demonstrate the Efficacy of Cangrelor (PCI)

Myocardial Infarction (MI) | Acute Coronary Syndromes (ACS)

United States
The Medicines Company

Terminated

Cangrelor Versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition. (Platform)

Atherosclerosis | Acute Coronary Syndrome (ACS)

United States
Medical University of Vienna

Completed

The Effect of Clopidogrel and Ticagrelor With and Without Acetylsalicylic Acid (ASA) on Hemostatic System Activation at the Site of Plug Formation in Vivo in Man

Acute Coronary Syndrome

Austria
The Medicines Company

Completed

Maintenance of Platelet Inhibition With Cangrelor (Bridge)

Acute Coronary Syndrome (ACS)

United States
Hôpital de la Timone

Unknown

Timing of Optimal Platelet Inhibition After Acute Coronary Syndrome (TOPIC)

Acute Coronary Syndrome | Antiplatelet Therapy | Coronary Stenting

France
Boehringer Ingelheim
Uppsala University

Completed

RE-DEEM Dose Finding Study for Dabigatran Etexilate in Patients With Acute Coronary Syndrome

Coronary Disease

United States, Belgium, Bulgaria, Canada, Czech Republic, Denmark, Finland, France, Georgia, Germany, Hungary, India, Ireland, Italy, Korea, Republic of, Netherlands, Norway, Poland, Romania, Russian Federation, Spain, Sweden, Ukraine, United Kingdom
Medical University of Vienna

Completed

Antithrombotic Triple Therapy in Humans

Atrial Fibrillation | Acute Coronary Syndrome

Austria
Eli Lilly and Company
Daiichi Sankyo Co., Ltd.

Completed

A Comparison of Prasugrel at PCI or Time of Diagnosis of Non-ST Elevation Myocardial Infarction (ACCOAST)

Acute Coronary Syndromes

Israel, Italy, Germany, Belgium, Poland, France, Austria, Netherlands, Turkey, Hungary, Lithuania, Romania, Canada, Slovakia, Czech Republic, Finland, Latvia, Portugal, Sweden
Ajou University School of Medicine
Dong-A Pharmaceutical

Completed

Point-of-Care Measurements of Platelet Inhibition After Clopidogrel Loading in Patients With Acute Coronary Syndrome: Comparison of Generic Clopidogrel Bisulfate (Plavitor®) With Original Clopidogrel Bisulfate (Plavix®)

Acute Coronary Syndrome

Korea, Republic of
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France

Completed

Identification of Clopidogrel CYP2C19 Metabolizer and Thienopyridine Treatment After an Acute Coronary Syndrome (GAMMA)

Acute Coronary Syndrome

France
The Medicines Company

Completed

A Clinical Trial Comparing Cangrelor to Clopidogrel Standard Therapy in Subjects Who Require Percutaneous Coronary Intervention (PCI) (CHAMPION PHOENIX) (CHAMPION)

Atherosclerosis | Acute Coronary Syndrome | Percutaneous Coronary Intervention

United States
Hopital Lariboisière

Unknown

Persistent Platelet Reactivity in Acute Coronary Syndrome

Acute Coronary Syndrome

France
Azienda Policlinico Umberto I

Unknown

Assessment of Coronary Flow Reserve by Doppler Flow WIre in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Differences Between the Loading Dose of Prasugrel and Ticagrelor .

ST Elevation Myocardial Infarction | Acute Coronary Syndrome | Unstable Angina | Non ST Elevation Myocardial Infarction

Italy
Azienda Policlinico Umberto I

Unknown

Assessment of Coronary Flow Reserve by Doppler Flow Wire in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention Differences Between the Loading Dose of Ticagrelor and Clopidogrel

ST Elevation Myocardial Infarction | Unstable Angina | Non ST Elevation Myocardial Infarction | Acute Coronary Syndrome:

Italy
University of Roma La Sapienza

Unknown

"Pharmacodynamic Comparison of Omeprazole Versus Pantoprazole on Platelet Reactivity in Patients With Acute Coronary Syndromes on Dual Antiplatelet Therapy With New P2Y12 Inhibitors" -Trial dOPPLER- (dOPPLER)

Coronary Artery Disease

Italy
Medical University of Vienna

Unknown

Platelet Function in Patients With an Acute Coronary Syndrome (ATLANTIS-ACS)

Acute Coronary Syndrome (ACS)

Austria
Chinese PLA General Hospital

Unknown

Clopidogrel Pharmacogenetic Score System (CPASS)

Acute Coronary Syndrome

China
Medical University of Silesia

Completed

Clinical Effects of Eptifibatide Administration in High Risk Patients Presenting With Non-ST Segment Elevation Acute Coronary Syndrome (NSTE-ACS) Requiring Urgent Coronary Artery Bypass Graft Surgery in Short- and Long-Term Follow-up

Non ST Elevation Myocardial Infarction

United States, Poland
University of Mississippi Medical Center

Terminated

Does An Abnormal PFA 100 Predict Bleeding After Renal Biopsy?

Hemorrhage | Kidney Failure, Chronic | Blood Platelet Disorders | Kidney Failure, Acute

United States
Drexel University College of Medicine

Completed

Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation or Isotretinoin in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Acute Lymphocytic Leukemia

Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Thrombocytopenia

United States
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo; Accumetrics, Inc.; Helena... and other collaborators

Completed

Platelet Hyperreactivity to Aspirin and Stroke (PLARAS)

Ischemia | Cardiovascular Diseases | Vascular Diseases | Stroke | Thrombosis | Atherosclerosis | Acute Coronary Syndrome | Cerebral Infarction

Brazil
Eisai Co., Ltd.

Completed

A Double-Blind Study of E5555 in Japanese Patients With Acute Coronary Syndrome

Acute Coronary Syndrome

Japan
Olivier F. Bertrand
Eli Lilly and Company; Cordis Corporation

Completed

A Randomized Trial of Early Discharge After Trans-radial Stenting of Coronary Arteries in Acute MI and Rescue-PCI (EASY-RESCUE)

Myocardial Infarction | Ischemia

Canada
Eli Lilly and Company
Duke Clinical Research Institute; Daiichi Sankyo Co., Ltd.

Completed

A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome Subjects (TRILOGY ACS)

Acute Coronary Syndrome

Argentina, Brazil, Canada, Italy, China, Puerto Rico, Australia, Romania, Russian Federation, France, Germany, United States, Belgium, Bulgaria, Poland, Ukraine, United Kingdom, Colombia, Hungary, Philippines, Croatia, Denmark, India, Chil... and more
Assistance Publique - Hôpitaux de Paris
Bristol-Myers Squibb; Sanofi; Institut National de la Santé Et de la Recherche... and other collaborators

Completed

Double Randomization of a Monitoring Adjusted Antiplatelet Treatment Versus a Common Antiplatelet Treatment for DES Implantation, and Interruption Versus Continuation of Double Antiplatelet Therapy (ARCTIC)

Coronary Artery Disease | Acute Coronary Syndrome

France
University of Patras

Completed

Standard (180mg) Versus Double (360mg) Loading Dose of Ticagrelor in Patients With ST-elevation Myocardial Infarction (STEMI), Undergoing Primary Percutaneous Coronary Intervention (PCI)

ST-elevation Myocardial Infarction

Greece
University of Sao Paulo General Hospital
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Residual Platelet Activity Despite Aspirin Utilization in Coronary Heart Disease

Coronary Heart Disease | Non ST-elevation Acute Coronary Syndromes

Brazil
Ruhr University of Bochum

Completed

The Bochum Optimizing Clopidogrel-Aspirin Therapy and MORTality Study (BOCLA-Mort) (BOCLA-Mort)

Coronary Artery Disease

Germany
University of Arizona

Unknown

Clopidogrel Resistance and Platelet Reactivity in Women Undergoing Percutaneous Coronary Intervention

Coronary Artery Disease | Acute Coronary Syndrome

United States
University Magna Graecia

Completed

Platelet Aggregation During the Shift From Clopidogrel to Ticagrelor (SHIFT-OVER)

Acute Coronary Syndrome

Italy
Gennaro Sardella

Unknown

Standard Clopidogrel Versus Prasugrel Low Dose Therapy in Elderly Patients With Acute Coronary Syndrome (RESET ELDERLY)

Coronary Artery Disease

Italy
University of Patras

Completed

Differential Effect of Ticagrelor Versus Prasugrel on the Adenosine-induced Coronary Vasodilatory Responses in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention

Acute Coronary Syndrome

Greece
University of Patras

Completed

Τicagrelor Versus Prasugrel in Diabetic Patients: a Pharmacodynamic Study

Coronary Artery Disease | Acute Coronary Syndrome

Greece
R&D Cardiologie

Completed

WOEST ( What is the Optimal antiplatElet & Anticoagulant Therapy in Patients With Oral Anticoagulation and Coronary StenTing) (WOEST)

Atrial Fibrillation | Stents | Anticoagulants | Platelet Aggregation Inhibitors

Netherlands, Belgium

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