Search clinical trials for: PHASE II

Total 43593 results

National Institute on Drug Abuse (NIDA)
University of Vermont

Completed

Alternate Day Buprenorphine Administration, Phase XII - 17

Opioid-Related Disorders

United States
The Japanese Society of Hypertension

Unknown

Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) Trial of Cardiovascular Events in High-Risk Hypertensive Patients

Cardiovascular Diseases | Hypertension

Japan
Advanz Pharma

Completed

Oxypurinol Compared With Placebo for Class III-IV NYHA Congestive Heart Failure

Congestive Heart Failure

United States
Pharmasset

Completed

A 14-Day Study of Racivir When Used in Combination in HIV-Infected Males

HIV Infections
Pharmasset

Completed

A Study of DPC 817 in HIV-Infected Males

HIV Infections

United States, Germany
Glaxo Wellcome

Completed

A Study of Zidovudine and T Lymphocyte Transfer in the Treatment of HIV Type III in Patients With AIDS

HIV Infections

United States
Sequus Pharmaceuticals

Completed

Randomized, Comparative Trial of DOX-SL (Stealth Liposomal Doxorubicin Hydrochloride) Versus Bleomycin and Vincristine in the Treatment of AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
Genentech, Inc.

Completed

A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Patients With AIDS and AIDS-Related Complex

HIV Infections

United States
Chiron Corporation

Completed

A Phase I Study of Subcutaneously Administered Proleukin (Aldesleukin) in HIV-Infected Patients

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.

Completed

A Phase I Study of the Safety and Pharmacokinetics of Recombinant Human CD4 Immunoglobulin (rCd4-IgG) Administered by Intravenous Bolus in Patients With AIDS and AIDS Related Complex

HIV Infections

United States
National Center for Research Resources (NCRR)
University of Texas

Completed

Phase I Study of Heme Arginate With or Without Tin Mesoporphyrin in Patients With Acute Attacks of Porphyria

Porphyria
Glaxo Wellcome

Completed

A Phase I Study to Evaluate the Pharmacokinetics, Safety and Antiviral Effects of Concurrent Administration of Zidovudine (AZT) and 2'3'-Dideoxyinosine (ddI) in Patients With Human Immunodeficiency Virus (HIV)

HIV Infections

United States
Sequus Pharmaceuticals

Unknown

A Comparison of DOX-SL Versus Adriamycin Plus Bleomycin Plus Vincristine in the Treatment of Severe AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
University of Minnesota

Unknown

Phase I Pilot Study of CD34 Enriched, Fanconi's Anemia Complementation Group C Gene Transduced Autologous Peripheral Blood Stem Cell Transplantation in Patients With Fanconi's Anemia

Fanconi's Anemia
National Institute on Drug Abuse (NIDA)
University of Vermont

Completed

Alternate-Day Buprenorphine Administration. Phase I - 3

Opioid-Related Disorders

United States
Otsuka America Pharmaceutical

Completed

A Phase I Study of Three Doses of OPC-8212 (Vesnarinone) in HIV-Infected Persons With CD4+ Cell Number > 300 Cells/mm3

HIV Infections

United States
Enzon Pharmaceuticals, Inc.

Terminated

Phase I Study of PEG-Paclitaxel In Patients With Advanced Solid Tumors & Lymphomas

Neoplasm Metastasis | Neoplasm | Lymphomas
Sandoz

Completed

An Open Label Phase I Study of Subcutaneously Administered Recombinant Human GM-CSF in Patients With AIDS Virus Infection and Leukopenia

HIV Infections | Cytopenias

United States
CancerVax Corporation

Unknown

Vaccine Therapy for Patients With Stage III Melanoma

Malignant Melanoma

United States, France, Australia, Canada, Germany, United Kingdom, Switzerland, Brazil, Ireland, Israel, Italy, Netherlands, New Zealand
National Institute on Drug Abuse (NIDA)
University of Vermont

Completed

Alternate-Day Buprenorphine. Phase V - 6

Opioid-Related Disorders

United States
Medical Research Laboratories International

Terminated

Implitapide in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) on Maximal Concurrent Lipid-Lowering Therapy

Familial Hypercholesterolemia

Netherlands, United States, Norway
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Trial To Evaluate the Safety and Immunogenicity of the UBI HIV-1MN PND Peptide Immunogen, Given by IM Injection, in Combination With the UBI Microparticulate Monovalent HIV-1 MN Branched Peptide Given Orally, in HIV-1 Uninfected Volunteers.

HIV Infections

United States
Hoffmann-La Roche

Completed

A Phase I Pharmacokinetic Study in HIV-Positive Subjects of Oral Ganciclovir and Concomitant Antiretroviral Zidovudine and Didanosine

HIV Infections | Cytomegalovirus Infections

United States
Glaxo Wellcome

Completed

An Oral Dose-Ranging Finding Study in Patients With HIV Disease, CDC Classification Groups IIB, III, and IV-C2

HIV Infections

United States
Northwestern Memorial Hospital

Completed

Phase I Study of High-Dose Cyclophosphamide and Total Body Irradiation With T Lymphocyte-Depleted Autologous Peripheral Blood Stem Cell or Bone Marrow Rescue in Patients With Multiple Sclerosis

Multiple Sclerosis

United States
University Hospital, Saarland

Unknown

Primary Prevention Study: Study on Obesity, Cardiovascular and Psycho-Social Characteristics in the City of Merzig

Depression | Obesity | Cardiovascular Disease | Stress

Germany
Glaxo Wellcome

Completed

A Phase I Trial to Evaluate the Safety, Pharmacokinetics and Antiviral Activity of 141W94 After Multiple Dosing in Patients With HIV Infection

HIV Infections

United States
Wellstat Therapeutics

Terminated

Phase I Study of PN401, Fluorouracil, Leucovorin and CPT-11 in Patients With Solid Tumors

Solid Tumors

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Safety and Immunogenicity Trial of UBI HIV Lipopeptide Vaccine Component P3C541b in HIV-1 Seronegative Human Subjects

HIV Infections

United States
Melbourne Health

Completed

Using the Drug Spironolactone to Test If It Reduces Protein Leakage From the Kidney

Diabetic Nephropathy | Proteinuria | Glomerulonephritis | Kidney Disease

Australia
National Center for Research Resources (NCRR)
University of Texas

Completed

Studies in Porphyria III: Heme and Tin Mesoporphyrin in Acute Porphyrias

Porphyria

United States
Astra USA

Completed

Safety and Efficacy of Intravenous Magnesium Sulfate in Modulating Changes in Symptoms and Divalent Cation Levels Associated With Foscavir Therapy: A Phase IV Randomized, Double-Blind, Placebo-Controlled, Cross-Over, Pilot Study

HIV Infections | Hypocalcemia | Cytomegalovirus Infections

United States
Genentech, Inc.

Completed

A Phase I Study of Recombinant Human CD4 Immunoglobulin G (rCD4-lgG) in Patients With HIV-Associated Immune Thrombocytopenic Purpura

HIV Infections | Immune Thrombocytopenic Purpura ( ITP )

United States
National Institute of Allergy and Infectious Diseases...
United Biomedical

Completed

A Phase I Safety and Immunogenicity Trial of UBI Microparticulate Monovalent HIV-1 MN Peptide Immunogen in HIV-1 Seronegative Human Subjects

HIV Infections

United States
Sequus Pharmaceuticals

Completed

Use of Stealth Liposomal Doxorubicin HCl ( DOX-SL ) in the Treatment of Moderate to Severe AIDS-Related Kaposi's Sarcoma.

HIV Infections | Sarcoma, Kaposi

United States
Lexigen Pharmaceuticals

Completed

Phase I Trial of S-1153 in Patients With HIV Infection

HIV Infections

United States
Northwestern Memorial Hospital

Unknown

Phase I Study of Immune Ablation and CD34+ Peripheral Blood Stem Cell Support in Patients With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States
Texas Biotechnology Corporation

Completed

Pharmacokinetics/Pharmacodynamics of Argatroban Injection in End-Stage Renal Disease Patients Undergoing Hemodialysis

Kidney Failure, Chronic | Renal Disease, End-Stage

United States
Parke-Davis

Completed

A Phase I Maximum Tolerated Dose Study of CI-1012 in Late-Stage HIV+ Patients

HIV Infections

United States
Daiichi Pharmaceuticals

Completed

A Phase I Trial of Tecogalan Sodium (DS-4152) Administered as an Infusion Every 21 Days

HIV Infections | Sarcoma, Kaposi

United States
Aronex Pharmaceuticals

Unknown

Aroplatin and Gemcitabine in Patients With Advanced Pancreatic Cancer Resistant to Standard Therapies

Pancreatic Neoplasms
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.

Completed

A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 Immunoglobulin G (rCD4-IgG) in Infants and Children With Documented HIV-1 Infection

HIV Infections

United States
National Institute on Drug Abuse (NIDA)
University of Vermont

Completed

Alternate-Day Buprenorphine Administration. Phase VII - 8

Opioid-Related Disorders

United States
U.S. Bioscience
Jacobus Pharmaceutical

Completed

Randomized Phase I Study of Trimetrexate Glucuronate (TMTX) With Leucovorin (LCV) Protection Plus Dapsone Versus Trimethoprim / Sulfamethoxazole (TMP/SMX) for Treatment of Moderately Severe Episodes of Pneumocystis Carinii Pneumonia

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
National Center for Research Resources (NCRR)
Stanford University

Completed

A Maintenance Extension of Phase I Pilot Study of Chimeric Anti-CD4 Antibody M-T412 in Patients With Multiple Sclerosis

Multiple Sclerosis
National Center for Research Resources (NCRR)

Unknown

Ingested Interferon Alpha: Prolongation or Permanence of the "Honeymoon" Phase in Newly Diagnosed Type 1 Diabetes Mellitus

Diabetes Mellitus, Type 1

United States
PhytoCeutica

Terminated

Safety Study of the Chemotherapy Modulator PHY906 in Patients With Advanced Colorectal Cancer

Diarrhea | Colorectal Neoplasms

United States
Genentech, Inc.

Completed

A Phase I Study of Recombinant CD4(rCD4) in Patients With AIDS and AIDS-Related Complex

HIV Infections

United States
Aronex Pharmaceuticals

Unknown

A Safety and Effectiveness Study of Aroplatin in Patients With Advanced Colorectal Cancer Resistant to Standard Therapies

Colorectal Neoplasms

United States
United Biomedical

Completed

A Phase I Safety and Immunogenicity Trial of UBI HIV Lipopeptide Immunotherapeutic P3C541b in HIV-1 Seropositive Human Subjects

HIV Infections

United States

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