Clinical Trials Sponsored by Synexus(UK)

Total 1317 results

Paion UK Ltd.
Premier Research Group plc

Completed

A Phase III Study of Remimazolam in Patients Undergoing Bronchoscopy

Bronchoscopy

United States
University of Oxford
Novartis; Cancer Research UK

Completed

Palliative Thoracic Radiotherapy Plus BKM120 (BKM120)

Carcinoma, Non-Small-Cell Lung

United Kingdom
Reckitt Benckiser Healthcare (UK) Limited
Simbec Research

Completed

Naproxen Sodium (2 x 220 mg) Fasted Comparative Bioavailability Study

Healthy
Generic Devices Consulting, Inc.
Biocompatibles UK Ltd

Terminated

Chemoembolization, Irinotecan Bead, Second Line Chemotherapy Treatment of Unresectable Metastatic Colorectal Cancer (PARAGON)

Unresectable Metastatic Colo-rectal Cancer

United States
University College, London
AstraZeneca; Cancer Research UK

Withdrawn

Phase I Trial of Vandetanib Combined With 131I-mIBG to Treat Patients With Advanced Phaeochromocytoma and Paraganglioma (VIBRaNT)

Paraganglioma | Phaeochromocytoma

United Kingdom
Macmillan Research Group UK
Sonal Foundation, India

Completed

Role of Psychoanalysis in Prevention of Girl Child Maltreatment and Neglect

Abuse Neglect | Social; Deprivation, Maltreatment Syndrome (Infant or Child)

India
University College, London
AstraZeneca; Cancer Research UK

Completed

Saracatinib and Paclitaxel in Platinum-resistant Ovarian Cancer (SaPPrOC)

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer

United Kingdom
Macmillan Research Group UK
Saibliss Healthcare Vision

Completed

Periodontal Therapy in a Primary Prevention of Cardiovascular Disease

Coronary Disease | Periodontitis

India
Cancer Research UK

Unknown

Study of Blood and Tissue Samples From Patients Receiving Androgen Deprivation for Newly Diagnosed Prostate Cancer

Prostate Cancer

United Kingdom
Cancer Research UK

Unknown

Study of Genes and the Environment in Patients With Ovarian Cancer in the East Anglia, Oxford, Trent, or West Midlands Regions of the United Kingdom

Ovarian Cancer

United Kingdom
Cancer Research UK

Unknown

Study of Genes and the Environment in Patients With Colorectal Cancer in the East Anglia Region of the United Kingdom

Colorectal Cancer

United Kingdom
Cancer Research UK

Unknown

Study of Genes and the Environment in Patients With Endometrial Cancer in the East Anglia, Oxford, Trent, or West Midlands Regions of the United Kingdom

Endometrial Cancer

United Kingdom
Cancer Research UK

Unknown

Combination Chemotherapy and Rituximab in Treating Patients With Diffuse Large B-Cell Non-Hodgkin Lymphoma

Lymphoma

United Kingdom
Cancer Research UK

Completed

Capecitabine and Oxaliplatin or Standard Follow-Up Care in Treating Patients Who Have Undergone Surgery for Locally Advanced Rectal Cancer

Colorectal Cancer

United Kingdom
University of Reading
Jordans Cereals (Biggleswade, UK)

Completed

Health Benefits of Whole Grain Oats in Population at Risk of Cardio-metabolic Disease

Cardiovascular Disease | Hypercholesterolemia

United Kingdom
Cancer Research UK

Unknown

Study of Blood and Tissue Samples From Patients With Stomach Cancer, Esophageal Cancer, or Gastroesophageal Junction Cancer

Gastric Cancer | Esophageal Cancer | Adenocarcinoma of the Gastroesophageal Junction

United Kingdom
Cancer Research UK

Unknown

Carmustine, Etoposide, Cytarabine, Melphalan, and Alemtuzumab Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

Lymphoma
Cancer Research UK

Completed

Combination Chemotherapy With or Without Rituximab in Treating Patients With Previously Treated Chronic Lymphocytic Leukemia

Leukemia

United Kingdom
Cancer Research UK

Unknown

Donor Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma

Lymphoma
Cancer Research UK

Completed

Radiation Therapy With or Without Chemotherapy in Treating Patients With Advanced Head and Neck Cancer

Head and Neck Cancer

United Kingdom, India
Cancer Research UK

Completed

Bryostatin 1 In Treating Patients With Progressive Kidney Cancer

Kidney Cancer

United Kingdom
Cancer Research UK

Completed

Gemcitabine With or Without Capecitabine in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

Pancreatic Cancer

United Kingdom
British Columbia Cancer Agency
Biocompatibles UK Ltd

Completed

Ability of a New Design of Iodine 125 Seed to Maintain Intended Position When Implanted in the Prostate (FAST)

Prostate Cancer

Canada
Zealand University Hospital
Holbaek Sygehus

Completed

Obstructive Sleep Apnea in Obese Children and Teenagers - Occurrence and Importance of Intervention

Sleep Apnea, Obstructive | Pediatric Obesity

Denmark
Karen Hoejmark Hansen

Completed

The Effect of Tranexamic Acid. A Randomised Study of Patients Undergoing Elective Lumbar Spine Surgery.

Pharmacological Action

Denmark
Sygehus Lillebaelt
Odense University Hospital

Completed

Vertebroplasty Compared With a Sham-procedure for Painful Acute Osteoporotic Vertebral Fractures (VOPE)

Osteoporotic Fractures

Denmark
Holbaek Sygehus
Odense University Hospital

Unknown

Clavicular Shortening Post-fracture - Does it Change? - a Prospective Study of 70 Patients

Stability of Clavicular Fractures Within the First 3 Weeks

Denmark
Kolding Sygehus
Hvidovre University Hospital

Unknown

Gene-Polymorphies in the P2X7 Gene in Patients With Osteoporotic Fractures

Hip Fracture

Denmark
King's College London
UK Research and Innovation

Not yet recruiting

Structured Tailored Rehabilitation After Hip Fragility Fracture (STRATIFY)

Hip Fractures
University of Leeds
Takeda; Cancer Research UK

Recruiting

The Role of Ixazomib in Autologous Stem Cell Transplant in Relapsed Myeloma - Myeloma XII (ACCoRd)

Multiple Myeloma

United Kingdom
Kiniksa Pharmaceuticals (UK), Ltd.

Completed

Study to Assess the Efficacy and Safety of Rilonacept Treatment in Participants With Recurrent Pericarditis (RHAPSODY)

Recurrent Pericarditis

United States, Israel, Australia, Italy
University of Liverpool
Metabolic Health Solutions UK

Completed

Energy Expenditure From ECAL Indirect Calorimeter in a Multicomponent Weight Management Service (ECAL)

Obesity | Severe Obesity | Sleep Apnoea

United Kingdom
King's College London
Mental Health Research UK

Withdrawn

Imagine a Brighter Future: An Intervention to Improve Positive Emotions in Young People (IMAGINE-P)

Depression | Anhedonia

United Kingdom
Imperial College London
Incyte Biosciences UK Ltd

Active, not recruiting

Itacitinib in Advanced Hepatocellular Carcinoma (JAKaL)

Advanced Hepatocellular Carcinoma

United Kingdom
University College, London
Pfizer; Cancer Research UK

Completed

Treatment of Patients With Diffuse Large B Cell Lymphoma Who Are Not Suitable for Anthracycline Containing Chemotherapy (INCA)

Diffuse Large B Cell Lymphoma

United Kingdom
Cancer Research UK
BioInvent International AB; Bloodwise

Completed

BI-1206 and an Anti-CD20 Antibody in Patients With CD32b Positive B-cell Lymphoma or Leukaemia

B-cell Lymphoma | Waldenström Macroglobulinemia | Chronic Lymphocytic Leukaemia

United Kingdom
Reckitt Benckiser Healthcare (UK) Limited
proDERM GmbH

Completed

A Clinical Investigation Into the Effectiveness and Safety of Five Water Based Personal Lubricants.

Vaginal Dryness | Dyspareunia

Germany
Queen Mary University of London
LAPresearch UK

Unknown

Dynamic Liver Tests in Liver Disease

Hepatitis B | Hepatitis C

United Kingdom
Paion UK Ltd.
Premier Research Group plc

Completed

Multiple Dose Safety and Efficacy Study Evaluating CNS 7056 Versus Midazolam in Patients Undergoing Colonoscopy

Sedation

United States
Reckitt Benckiser Healthcare (UK) Limited
Simbec Research

Completed

Ibuprofen Bioavailability Study

Healthy

United Kingdom
Queen Mary University of London
Headspace UK

Completed

Mindfulness Meditation for Chronic Pelvic Pain Management (MEMPHIS)

Chronic Pelvic Pain

United Kingdom
Singapore Eye Research Institute
UK Network Medical

Completed

The SNEC DSAEK EndoGlide Clinical Trial

Bullous Keratopathy

Singapore
Velindre NHS Trust
AstraZeneca; Cancer Research UK

Unknown

Fulvestrant +/- Vandetanib in Advanced Aromatase Inhibitor Resistant Breast Cancer (FURVA)

Neoplasms

United Kingdom
Reckitt Benckiser Healthcare (UK) Limited
Simbec Research

Completed

Ibuprofen and Paracetamol Pharmacokinetic Study

Healthy Volunteer Study
Universitaire Ziekenhuizen KU Leuven
Biocompatibles UK Ltd

Withdrawn

Chemoembolisation With CPT11 Loaded DC Bead With Cetuximab and 5FU/LV in First Line in Patients With KRAS Wildtype mCRC

Colorectal Cancer | Liver Metastases
Cancer Research UK

Unknown

Blood Samples From Healthy Volunteers for Genetic Studies in the East Anglia Region of the United Kingdom

Healthy, no Evidence of Disease

United Kingdom
Cancer Research UK

Unknown

High-Dose Chemotherapy Given Together With Peripheral Blood Stem Cell Transplant in Treating Patients With Intestinal T-Cell Lymphoma

Lymphoma | Small Intestine Cancer

United Kingdom
Cancer Research UK

Unknown

Study of Genes and the Environment in Patients With Prostate Cancer Residing in the East Anglia, Trent, or West Midlands Regions of the United Kingdom

Prostate Cancer

United Kingdom
Cancer Research UK

Unknown

Study of Genes and Environment in Patients With Cancer in East Anglia, Trent, or West Midlands Regions of the United Kingdom

Lymphoma | Kidney Cancer | Pancreatic Cancer | Esophageal Cancer | Brain and Central Nervous System Tumors | Bladder Cancer | Intraocular Melanoma | Melanoma (Skin) | Transitional Cell Cancer of the Renal Pelvis and Ureter

United Kingdom
Cancer Research UK

Unknown

Study of Genes and Environment in Patients With Breast Cancer in the East Anglia Region of the United Kingdom

Breast Cancer

United Kingdom

Clinical Trials Sponsored by Synexus(UK)

Sponsors and Collaborators

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